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PD1×VEGF双抗SSGJ707
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三生制药(01530.HK):天价DEAL刷记录 临床开发再加速
Ge Long Hui· 2025-05-23 17:51
Group 1 - The company signed a licensing agreement with Pfizer for the PD1×VEGF dual antibody SSGJ707, granting Pfizer global rights (excluding mainland China) for development, production, and commercialization, with an upfront payment of $1.25 billion and potential milestone payments of $4.8 billion [1] - The $1.25 billion upfront payment sets a record for Chinese innovative drug licensing out, indicating strong market validation for the PD1×VEGF dual antibody sector [1] - The clinical development speed of SSGJ707 in the U.S. is expected to be rapid due to Pfizer's robust clinical development platform and commercialization system [1] Group 2 - The company has four mid-to-late stage clinical assets (IL17, IL1β, IL4R, IL5 monoclonal antibodies), each projected to generate over $1 billion in revenue, with IL17 expected to commercialize in 2025 [2] - The company forecasts revenue growth from 2025 to 2027, estimating revenues of 10.201 billion, 11.494 billion, and 13.153 billion yuan, with year-on-year growth rates of 12.0%, 12.7%, and 14.4% respectively [2] - The company anticipates net profit growth during the same period, projecting net profits of 2.345 billion, 2.648 billion, and 3.027 billion yuan, with growth rates of 12.2%, 12.9%, and 14.3% respectively [2]
三生国健(688336):母公司天价DEAL刷记录 临床开发再加速
Xin Lang Cai Jing· 2025-05-23 10:32
Core Insights - The company has signed a licensing agreement with Pfizer for the PD1×VEGF dual antibody SSGJ707, granting Pfizer global rights (excluding mainland China) for development, production, and commercialization, with an upfront payment of $1.25 billion and potential milestone payments of up to $4.8 billion [1] - The PD1×VEGF dual antibody market is validated, with significant clinical results from competitors enhancing expectations for IO dual antibodies as alternatives to PD1 [2] - The company is expected to achieve substantial revenue growth from its main business, with several late-stage clinical assets projected to generate significant sales [2] Company Developments - The upfront payment of $1.25 billion is the largest for a Chinese innovative drug license out, setting a new record [1] - The company retains a 30% stake in the SSGJ707 project, indicating a strong interest in its future success [1] - The company is positioned as a leader in the domestic autoimmune field, with robust R&D capabilities and a pipeline of clinical assets nearing commercialization [3] Financial Projections - Revenue forecasts for 2025-2027 are projected at 1.37 billion, 1.57 billion, and 1.94 billion yuan, respectively, with net profits expected to be 300 million, 333 million, and 416 million yuan [3] - The company is anticipated to commercialize its IL17 monoclonal antibody by 2025 and submit an NDA for its IL1β monoclonal antibody in the same year, targeting a market with limited competition [2][3]