Repligen Conference Call Summary Company Overview - **Company**: Repligen (NasdaqGS:RGEN) - **Date**: November 11, 2025 - **Key Performance**: Achieved 18% organic growth in Q3, with all key product areas showing double-digit growth [1][2] Core Insights Financial Performance - **Q3 Results**: Non-COVID organic growth of 16% year-to-date [2] - **Operating Margins**: 14.2%, a decrease of 70 basis points [1] - **Earnings Beat**: Exceeded market expectations by $0.05 on the bottom line [1] Product Portfolio and Market Segments - **Diverse Portfolio**: Emphasized the broad and innovative product range, with analytics and protein franchises outperforming expectations [3] - **Market Recovery**: Notable recovery in biopharma and CDMO sectors, with small biotech showing a significant rebound in sales and orders [4] - **Emerging Biotech**: Defined as biotech companies without commercial products; funding increased to approximately $12 billion in Q3, up from $8.9 billion in Q2 [6] Geographic Insights - **China Market**: Primarily driven by established pharma companies rather than emerging biotech; order intake slowed due to inventory buildup [8][54] Growth Projections - **Filtration Outlook**: Expected growth of 10-12%, with a focus on fluid management and delays in order deliveries affecting projections [12][15] - **Chrome Segment**: Experienced significant growth due to successful conversions of big pharma customers [18] - **Protein Segment**: Transitioned to a more autonomous business model, with expectations for double-digit growth driven by custom and catalog resins [21][25] New Modalities and Future Opportunities - **New Modalities**: Positive outlook for new modalities, including cell therapy and antibody-drug conjugates, with a diversified portfolio mitigating risks from specific programs [28][29] - **Cell Therapy**: Strong demand anticipated, particularly for ATF technology, with plans to expand product offerings [32] Operational and Margin Considerations - **Operational Expenses**: Organic OpEx growth of 14%, with a target to align OpEx growth with top-line growth in the coming years [48][49] - **Margin Goals**: Aiming for 30% EBITDA by 2030 and mid-50s gross margin in the next few years [51][52] Strategic Initiatives - **Onshoring Trends**: Anticipated RFPs related to onshoring expected to emerge by mid-2026, presenting significant opportunities for bioprocessing companies [38][39] - **Hardware Growth**: Hardware revenue increased by 20%, with expectations for continued growth driven by differentiated product offerings [42] Conclusion - **Market Positioning**: Repligen aims to maintain a growth rate of 5% above market growth, leveraging its innovative portfolio and clinical exposure to drive demand [57][58]

Financial Data and Key Metrics Changes - For Q3 2025, the company reported net income of $11.9 million or $0.17 per share, down from $48.2 million or $0.69 per diluted share in Q3 2024 [8] - Revenue for the quarter was $508.5 million, a decrease of 22.8% year over year, attributed to exiting ethanol marketing for Tarleton and placing the Fairmont ethanol asset on cold maintenance [9] - Adjusted EBITDA for Q3 2025 was $52.6 million, slightly down from $53.3 million in Q3 2024 [8][9] - The company strengthened its balance sheet by retiring approximately $130 million of high-cost debt and refinancing most of its 2027 convertible debt with a new $200 million facility due in 2030 [5][9] Business Line Data and Key Metrics Changes - The operational performance of the plants reached over 101% capacity utilization, the highest level reported in over a decade, driven by operational excellence programs [6][18] - The company recognized $25 million in production tax credit value during the quarter and anticipates an additional $15-$25 million benefit in Q4 2025 [7][20] Market Data and Key Metrics Changes - Ethanol prices increased by approximately $0.25-$0.30 per gallon in August and September, while corn prices remained subdued due to favorable weather supporting larger yields [19] - The overall margin structure improved significantly in the second half of Q3 and early Q4, driven by tighter ethanol supplies and lower input costs [19] Company Strategy and Development Direction - The company has restructured its business to focus on value creation and strong cash flows, with a clear capital allocation strategy prioritizing operational excellence and reducing carbon intensity [5][17] - The carbon capture strategy is operational, with all three Nebraska facilities capturing CO2 and generating credits, marking a significant step in the company's decarbonization efforts [21] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to deliver sustainable, profitable results and highlighted the importance of executing on carbon program opportunities [4][23] - The company anticipates a solid Q4 performance, with margins remaining attractive despite expected seasonal volatility [20] Other Important Information - The company has no significant debt maturities for the next several years, allowing it to focus on operational initiatives [16] - Capital expenditures for Q3 were $4 million, with expectations of $5-10 million for the remainder of 2025, excluding fully financed carbon capture equipment [13] Q&A Session Summary Question: Key challenges for the next 9-12 months - Management highlighted the focus on managing costs and ensuring plant assets remain competitive, while also emphasizing the need to monetize tax credits and run the plants efficiently [23] Question: Uses of cash generation in 2026 and 2027 - Management indicated that cash would be used to maintain operating assets, reduce carbon intensity, and potentially return value to shareholders [26][27] Question: Incremental unlocks beyond Advantage Nebraska strategy - Management adjusted the expected EBITDA contribution from non-Nebraska assets to around $38 million, focusing on improving efficiency and reducing carbon intensity [34] Question: Rationale behind convertible debt restructuring - The rationale was to eliminate debt overhang and allow the organization to focus on day-to-day operations [37] Question: Changes at the plants and low CapEx - Management noted that improvements in capacity utilization were driven by operational focus rather than significant new investments [41][42] Question: Contribution of 45Z credits in Q4 - Management confirmed that the range of $15 million-$25 million in credits is based on execution and capture efficiency, with ongoing efforts to improve performance [45] Question: Status of clean sugar technology and commercialization path - Management indicated that while the technology is functional, additional CapEx is required to unlock its full potential, and a reevaluation will occur mid-2026 [66][67]

Summary of Gevo Conference Call - September 25, 2025 Company Overview - Gevo is focused on producing renewable resource-based fuels, including jet fuel, gasoline, and diesel, from renewable carbon sources, aiming for carbon-negative footprints [1][2] - The company has a team with extensive experience in both agricultural and petrochemical sectors, having previously developed biodegradable plastics [2] Business Model and Operations - Gevo's production process involves converting carbohydrates into hydrocarbons through alcohols like ethanol and isobutanol, utilizing established petrochemical industry methods [3] - The company operates four business segments, with Gevo Fuels being a key area, including a recently acquired ethanol plant in North Dakota, currently operating at 12% capacity [3][4] - The company emphasizes the economic benefits of using corn as a raw material, clarifying that the corn used is not for human consumption but rather for ethanol and protein production [5][6] Carbon Management and Market Opportunities - Gevo is involved in carbon capture and removal, generating Carbon Dioxide Removal (CDR) credits, which are sold in voluntary carbon markets [4][10] - The company distinguishes between CDRs and the 45Z tax credit, highlighting the potential revenue from CDRs ranging from $100 to $300 per ton [10][11] - Current adjusted EBITDA is approximately $20 million annually, with projections to reach $40 million and potentially $110 million in the near future through optimized operations [11][12] Market Demand and Future Growth - U.S. jet fuel demand is projected to increase, with a significant shortfall expected by 2035, creating opportunities for renewable jet fuel (SAF) commercialization [14][15] - Gevo's production costs for renewable jet fuel are competitive with traditional jet fuel, positioning the company favorably in the market [16] - The company plans to build Alcohol-to-Jet (ATJ) plants, which are expected to significantly enhance EBITDA by approximately $150 million per site [17][18] Strategic Initiatives - Gevo aims to optimize cash flow and expand capacity at its North Dakota site, with plans to build ATJ plants using a modular approach to reduce execution risks [20][21] - The company is focused on creating a reproducible model for plant deployment, emphasizing the importance of financing and operational efficiency [29] Economic and Environmental Impact - Gevo's operations are positioned to contribute to rural economic development, creating jobs and generating significant regional economic impact [18] - The company aligns with energy security goals, providing economical hydrocarbon products while addressing carbon emissions [18][19] Conclusion - Gevo is strategically positioned in the renewable fuels market, leveraging its expertise in agriculture and petrochemicals to capitalize on growing demand for sustainable energy solutions while managing carbon emissions effectively [19][20]

Financial Data and Key Metrics Changes - Sysco reported $81 billion in sales for the most recent year, with over 60% of revenue coming from restaurants, reflecting a 3% year-on-year growth in the restaurant segment [2][41] - The company expects FY 2026 sales growth of 3% to 5% and EPS growth of 1% to 3%, with adjusted EPS growth projected at 5% to 7% [38][50] - Sysco achieved a gross margin of 18.4%, which is 1.3 times higher than the average core peer, and an adjusted operating margin of over 4%, approximately 1.5 times higher than peers [45][46] Business Line Data and Key Metrics Changes - Sysco's specialty business, valued at $9 billion, is more than three times the size of its next biggest competitor in that space [5] - The U.S. Broadline business has shown positive inflection, with expectations for continued growth in Q1 [17][60] - The FreshPoint produce business experienced a drag due to exiting a business line, impacting the overall U.S. Foodservice (USFS) performance [18][56] Market Data and Key Metrics Changes - Sysco's international business is growing faster than its domestic core business, with a significant opportunity for expansion valued at over $10 billion [12][13] - The company has seen double-digit growth in its international segment for seven consecutive quarters [71] - The local case growth is improving, with Sysco's local business performing better than large national chains [56][64] Company Strategy and Development Direction - Sysco aims to leverage its size and scale to maintain its market leadership and drive profitability across various segments [4][40] - The company is focused on expanding its specialty business and enhancing its operational efficiencies through strategic sourcing and total team selling [45][46] - Sysco is committed to a balanced capital allocation strategy, investing in growth while maintaining an investment-grade balance sheet [48][82] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving FY 2026 guidance based on self-help initiatives and momentum in local case growth [68][70] - The overall consumer health is stabilizing, with improvements in foot traffic to restaurants noted [74][75] - Sysco is cautiously optimistic about the full year, expecting to grow by taking market share profitably [76][78] Other Important Information - Sysco has implemented new initiatives such as the Perks loyalty program and AI360 sales tool to enhance customer service and sales productivity [28][34] - The company plans to invest approximately $1 billion in share repurchases under current market conditions [83] Q&A Session Summary Question: Local case growth and momentum - Management highlighted that local business is outperforming national chains, with positive expectations for USBL in Q1 [56][60] - The retention and productivity of the sales workforce have improved, contributing to the positive momentum [57][61] Question: Confidence in FY 2026 guidance and consumer health - Management emphasized that guidance is based on self-help initiatives and momentum across various business segments, including international growth [68][70] - The consumer health is stabilizing, with improvements noted in restaurant traffic and performance in non-commercial sectors [74][76]

Financial Data and Key Metrics Changes - For Q2 2025, the company reported a net loss of $72.2 million or $1.09 per share, compared to a loss of $24.4 million or $0.38 per share in Q2 2024, reflecting a significant increase in losses [16][19] - Revenue for the quarter was $552.8 million, down 10.7% year-over-year, primarily due to exiting ethanol marketing and placing the Fairmont ethanol asset on care and maintenance [18][19] - Adjusted EBITDA for Q2 2025 was $16.4 million, compared to $5 million in Q2 2024, indicating improved operational performance despite the overall revenue decline [19] Business Line Data and Key Metrics Changes - The company has focused on core operations and has executed several non-core asset sales, including the GP Ferrelson joint venture, which has improved liquidity and operational focus [12][13] - The operational execution has led to 99% capacity utilization across the fleet of operating assets, with the highest ethanol yields in company history [24][26] Market Data and Key Metrics Changes - The market has seen improvements due to strong ethanol exports and supportive policies regarding renewable volume obligations, which have expanded ethanol crush margins [29][30] - The company is currently 65% crushed for Q3, indicating strong operational performance and market conditions [29][100] Company Strategy and Development Direction - The company is narrowing its focus to core operations and enhancing profitability through a carbon strategy, with significant progress in constructing CCS infrastructure [9][10] - The recent legislation, including the One Big Beautiful Bill Act, has extended the 45Z clean fuel production tax credit through 2029, positively impacting the company's strategic investments [11][12] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to improve profitability and cash flows, particularly with the anticipated startup of carbon monetization in Q4 2025 [33][39] - The company expects to achieve an annualized EBITDA contribution of over $150 million from its decarbonization strategy by 2026 [12][49] Other Important Information - The company has successfully extended the maturity of its junior mezzanine notes and is evaluating various financing solutions to support long-term growth [14][15] - Continuous improvement initiatives have led to a $50 million cost reduction target being met, with further efficiencies being identified [12][34] Q&A Session All Questions and Answers Question: Can you help frame the EBITDA potential in the back half of the year and into 2026? - Management indicated a stronger EBITDA margin outlook supported by rising corn oil prices and strong ethanol exports, with carbon monetization expected to contribute $20-25 million in Q4 [39] Question: What was the thought process behind the sale of the stake in the Darrelson JV? - The asset was deemed non-core, and data-driven decisions indicated it was sensible to exit at this time [41][42] Question: Can you clarify cash flows and the impact of RIN sales? - The $22.6 million from RIN sales was included in operating cash, and the proceeds from the Darrelson sale were collected in July, contributing positively to Q3 cash flow [46][47] Question: What is the expected impact of the 45Z credits? - The carbon opportunity has increased to $150 million for 2026 due to favorable policy changes, with all plants expected to qualify for the 45Z tax credits [49][51] Question: How should investors think about the capital structure and cash flows from carbon monetization? - Significant cash flows from carbon monetization are expected to accrue directly to the company, providing free cash flows for capital allocation [55][58] Question: What is the current state of the export market? - The export market is strong, with projections to reach 2.1 billion gallons, supported by increased demand from Canada, India, and the EU [108][110]

Financial Data and Key Metrics Changes - The company reported a net loss of $72.9 million or a loss of $1.14 per share for Q1 2025, compared to a net loss of $51.4 million or $0.81 per share in Q1 2024 [23] - Revenue for the quarter was $601.5 million, up 0.7% year over year [24] - Adjusted EBITDA excluding restructuring charges was a loss of $24.2 million, compared to a negative $21.5 million in Q1 last year [26] - SG&A totaled $42.9 million, an increase of $11.1 million from the prior year due to restructuring and severance charges [27] Business Line Data and Key Metrics Changes - The company achieved a record 100% utilization rate across its nine operating plants, demonstrating strong asset performance [25] - The anticipated consolidated SG&A run rate is expected to decline from $118 million in 2024 to approximately $93 million by year-end 2025 [8][27] - The company has achieved $30 million in annualized cost savings and expects an additional $15 million from a recently announced ethanol marketing partnership [7] Market Data and Key Metrics Changes - U.S. ethanol exports are expected to surpass last year's record of nearly 2 billion gallons in 2025 [18] - Ethanol margins have strengthened heading into Q2 and Q3, supported by firmer corn oil fundamentals and anticipated increases in renewable volume obligations [18] - Current ethanol inventory levels are at 25 million barrels, with expectations to drop towards 23 million as the driving season begins [81] Company Strategy and Development Direction - The company is focused on returning to sustained profitability through disciplined execution and operational excellence [5][6] - A strategic marketing partnership with EcoEnergy has been established to enhance scale and optimize transportation and marketing economics [19] - The company is pausing its clean sugar technology initiative to maximize ethanol production and improve profitability at the Shenandoah site [15][108] Management's Comments on Operating Environment and Future Outlook - Management acknowledges that performance has not met expectations but is committed to improving operational efficiency and profitability [5] - The company is optimistic about the carbon platform and is actively engaged in monetizing carbon credits [31][33] - Management expects to achieve positive EBITDA for the remainder of the year based on current market conditions and actions taken [34] Other Important Information - The company has executed a $30 million line of credit to enhance liquidity and is actively pursuing non-core asset sales [28][71] - Capital expenditures in Q1 were $16.7 million, with expectations of approximately $20 million for the remainder of 2025 [29] - The company is undergoing a strategic review, considering various paths including a potential sale or asset divestitures [32] Q&A Session Summary Question: Can you elaborate on the hedging framework and its reestablishment? - Management emphasized that hedging is a good practice for managing risk and is based on market opportunities, with a systematic approach supported by analytics [39][41] Question: What is the status of the CEO search? - The process is ongoing, nearing final stages, with a focus on candidates who can bring relevant industry experience [44] Question: Can you provide updates on carbon capture construction timelines? - Construction is on track for early Q4 startup, with no anticipated major delays [48] Question: What are the impacts of potential tariffs on product exports? - Currently, there has been no adverse impact from tariffs, and the company is optimistic about potential trade opportunities [49][52] Question: How is the company addressing the protein market dynamics? - The domestic protein market is expected to be flat, but the company is focusing on higher-margin segments like pet food and aqua feed [62]

Financial Data and Key Metrics Changes - The company reported a net loss of $72.9 million or a loss of $1.14 per share for Q1 2025, compared to a net loss of $51.4 million or $0.81 per share in Q1 2024 [23] - Revenue for the quarter was $601.5 million, up 0.7% year over year [24] - Adjusted EBITDA excluding restructuring charges was a loss of $24.2 million, compared to a negative $21.5 million in Q1 last year [26] - SG&A totaled $42.9 million, an increase of $11.1 million from the prior year due to restructuring and severance charges [27] Business Line Data and Key Metrics Changes - The company achieved a record 100% utilization rate across its nine operating plants, demonstrating strong asset performance [25] - The anticipated consolidated SG&A run rate is expected to decline from $118 million in 2024 to approximately $93 million by year-end 2025 [8][27] - The company has achieved $30 million in annualized cost savings and expects to reach a total of $50 million in cost reductions [6][7] Market Data and Key Metrics Changes - U.S. ethanol exports are expected to surpass last year's record of nearly 2 billion gallons in 2025 [18] - Ethanol market fundamentals showed typical seasonal weakness in Q1, but margins have strengthened heading into Q2 and Q3 [17] - Current ethanol inventory levels are at 25 million barrels, with expectations to drop towards 23 million as the driving season begins [81] Company Strategy and Development Direction - The company is focused on returning to sustained profitability and has executed a zero-based approach to its cost structure [5][6] - A strategic marketing partnership with EcoEnergy has been established to enhance scale and optimize transportation and marketing economics [19] - The company is pausing its clean sugar technology initiative to maximize ethanol production and improve operational efficiency [15][30] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving positive EBITDA for the remainder of the year based on current market conditions and actions taken [34] - The carbon strategy remains on track, with construction of carbon compression infrastructure advancing as planned [30] - Management acknowledged the challenges faced in the protein business but remains committed to executing the strategy [91] Other Important Information - The company has strengthened its liquidity position, with $126.6 million in cash equivalents and restricted cash at quarter-end [28] - Capital expenditures in Q1 were $16.7 million, with expectations for the remainder of 2025 to be around $20 million [29] - The company is actively engaged in a strategic review, considering various paths including a company sale or asset divestitures [32] Q&A Session Summary Question: Can you provide insight into the hedging framework and its reestablishment? - Management emphasized that hedging is a good practice for managing risk and that they are locking in margins when market opportunities arise [39][41] Question: What is the status of the CEO search? - The process is ongoing, nearing final stages, with a focus on candidates who can bring relevant industry experience [44] Question: Can you provide updates on carbon capture construction timelines? - Construction is on track for early Q4 startup, with no major delays anticipated [48] Question: What are the potential impacts of tariffs on product exports? - Currently, there has been no adverse impact from tariffs, but the situation remains unpredictable [49][52] Question: How is the company addressing the protein market dynamics? - The domestic protein market is expected to be flat, but the company is focusing on higher-margin segments like pet food and aquaculture [62]