对于一家成立仅四年的biotech企业而言，要想获得资本的青睐，离不开创新产品的加持。经过数十年的 发展，小核酸药物的药物设计和递送技术日益成熟，经历了从概念验证到人体临床试验的验证过程，其 适应证范围也从罕见病逐渐扩展到常见病领域。 在创新药资本寒冬中，一家成立仅四年的中国生物技术公司凭借三款临床阶段的小核酸药物，逆势完成 近5000万美元融资，专注于心血管代谢疾病市场，特别是在心血管慢病管理领域，这一领域在近两年成 为投资者关注的热点。 近日，靖因药业宣布成功完成近5000万美元B2轮融资，以加速其心血管代谢疾病的新型小干扰 RNA(siRNA)疗法的临床开发，并持续创新其下一代RNA递送技术。本轮融资由全球知名产业投资机构 领投，博远资本与现有投资者奥博资本，泓元资本和汉康资本共同参与。靖因药业累计融资已达1.5亿 美元，这一成绩在2025年上半年中国创新药公司融资普遍活跃的背景下显得尤为突出。 靖因药业的成就远不止于此。在成功融资后不久，该公司即宣布与CRISPR Therapeutics达成战略合作， 双方将共同开发并商业化新一代长效凝血因子XI（FXI）靶向小干扰RNA（siRNA）疗法SRSD1 ...

Financing Overview - A total of 11 financing events occurred in Shanghai this week, with 9 disclosing amounts totaling approximately 1.98 billion yuan [5][8] - The majority of financing events were concentrated in the Pudong New Area and Songjiang District, each with 2 events, while other areas had 1 event each [5] - Angel round financing was the most common, with 5 events, followed by 2 events each in Series B and strategic financing [8] Company Financing Dynamics - Xiangdao Travel announced the completion of over 1.3 billion yuan in Series C financing, aimed at expanding its market presence and enhancing its service offerings [14][15] - Jingyin Pharmaceutical completed nearly 50 million USD in B+ round financing, which will be used to advance its clinical pipeline and product development [16][18] - Pait Fresh Life secured 25 million USD in angel round financing to enhance its supply chain and product innovation in the pet food sector [19][20] - Kaan Chuang Neng completed several million yuan in Pre-A+ round financing, focusing on the development of hydrogen liquefaction systems [21][22] - Qianjue Robotics raised several million yuan in angel round financing to accelerate technology development and product iteration [23][24] - Aokun Technology completed several million yuan in angel round financing, which will be used for aviation measurement and control product development [25][26] - Baiyi Yuan Biotechnology received several million yuan in strategic financing from Kangzhe Pharmaceutical to support product development and market expansion [27][28] Industry Focus - The advanced manufacturing sector saw 3 financing events this week, focusing on aerospace, sensors, and communication technologies [29] - The Shanghai Institute of Microsystem and Information Technology made significant progress in developing high-performance MEMS fast-response mirrors for satellite laser communication [29][30] - Shanghai is committed to enhancing its manufacturing capabilities through policies aimed at supporting enterprise development and achieving high-quality growth in the manufacturing sector [30]