国元证券股份有限公司 关于安徽峆一药业股份有限公司 关联交易的核查意见 国元证券股份有限公司（以下简称"保荐机构"或"国元证券"）作为安徽峆一 药业股份有限公司（以下简称"峆一药业"或"公司"）本次向不特定合格投资者公 开发行股票并在北京证券交易所上市的保荐机构，根据《证券发行上市保荐业务 管理办法》《北京证券交易所上市公司持续监管办法（试行）》《北京证券交易所 证券发行上市保荐业务管理细则》《北京证券交易所股票上市规则（试行）》等相 关法律、法规和规范性文件的规定，对峆一药业关联交易事项进行核查，具体核 查情况如下： 一、关联交易基本情况 根据峆一药业及合资控股子公司安徽峆一达善医药有限公司（以下简称"峆 一达善"）经营需要，拟委托沈阳达善医药科技有限公司（以下简称"沈阳达善"） 开发制剂合同，合计总金额 595 万元，具体内容以最终签署的合同为准。 | 名称 | 沈阳达善医药科技有限公司 | | --- | --- | | 住所 | 辽宁省沈阳市浑南区上深沟村 860-6 号（F9）310 房间 | | 注册地址 | 辽宁省沈阳市浑南区上深沟村 860-6 号（F9）310 房间 | | 企业类型 | 有 ...

RSM | 容诚 审计报告 安徽哈一药业股份有限公司 容诚审字[2025]230Z0376 号 容诚会计师事务所(特殊普通合伙) 中国 · 北京 您可使用手机"扫一扫"或进入"注册会计师行业统一监管平台（http://ac.mof.gov.cn）"进行查测 "社 目 录 | 序号 | 内 容 | 页码 | | --- | --- | --- | | 1 | 审计报告 | 1-6 | | 2 | 合并资产负债表 | 1 | | 3 | 合并利润表 | 2 | | 4 | 合并现金流量表 | 3 | | 5 | 合并所有者权益变动表 | 4 - 5 | | 6 | 母公司资产负债表 | 6 | | 7 | 母公司利润表 | 7 | | 8 | 母公司现金流量表 | 8 | | 9 | 母公司所有者权益变动表 | 9 - 10 | | 10 | 财务报表附注 | 11 - 115 | 审 计 报 告 容诚审字[2025]230Z0376 号 安徽哈一药业股份有限公司全体股东: 一、审计意见 我们审计了安徽哈一药业股份有限公司(以下简称哈一药业)财务报表,包 括 2024 年 12 月 31 日的合并及母公司资产负债 ...

国元证券股份有限公司 关于安徽峆一药业股份有限公司 使用闲置募集资金购买理财产品的核查意见 国元证券股份有限公司（以下简称"保荐机构"或"国元证券"）作为安徽峆一 药业股份有限公司（以下简称"峆一药业"或"公司"）本次向不特定合格投资者公 开发行股票并在北京证券交易所上市的保荐机构，根据《证券发行上市保荐业务 管理办法》《北京证券交易所上市公司持续监管办法（试行）》《北京证券交易所 证券发行上市保荐业务管理细则》《北京证券交易所股票上市规则（试行）》等相 关法律、法规和规范性文件的规定，对峆一药业使用闲置募集资金购买理财产品 的事项进行核查，具体核查情况如下： 一、募集资金基本情况 2023 年 2 月 13 日，安徽峆一药业股份有限公司发行普通股 880 万股，发行 方式为向不特定合格投资者公开发行，发行价格为 12.62 元/股，募集资金总额为 11,105.60 万元，扣除发行费用 1,600.15 万元（不含税），募集资金净额为 9,505.45 万元，到账时间为 2023 年 2 月 16 日并由容诚会计师事务所（特殊普通合伙）进 行验资，出具了《验资报告》（容诚验字〔2023〕230Z0040 号 ...

【RSM | 容 诚 内部控制审计报告 安徽哈一药业股份有限公司 容诚审字|2025|230Z0377 号 容诚会计师事务所(特殊普通合伙) 中国 · 北京 您可使用手机"扫一扫"或进入"注册会计师行业统一监管平台（http://ac.mof.gov.cn）"进行查 ：" 内部控制审计报告 按照《企业内部控制基本规范》、《企业内部控制应用指引》、《企业内部 控制评价指引》的规定,建立健全和有效实施内部控制,并评价其有效性是哈一 药业董事会的责任。 二、注册会计师的责任 我们的责任是在实施审计工作的基础上,对财务报告内部控制的有效性发表 审计意见,并对注意到的非财务报告内部控制的重大缺陷进行披露。 三、内部控制的固有局限性 内部控制具有固有局限性,存在不能防止和发现错报的可能性。此外,由于 情况的变化可能导致内部控制变得不恰当,或对控制政策和程序遵循的程度降低, 根据内部控制审计结果推测未来内部控制的有效性具有一定风险。 四、财务报告内部控制审计意见 我们认为，哈一药业于 2024 年 12 月 31 日按照《企业内部控制基本规范》和 相关规定在所有重大方面保持了有效的财务报告内部控制。 容诚审字[2025]2 ...

证券代码：430478 证券简称：峆一药业 公告编号：2025-030 2024 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承 担个别及连带法律责任。 本人潘平作为安徽峆一药业股份有限公司（以下简称"公司"）的独立董 事，在任职期间严格按照《公司法》《证券法》《公司章程》《北京证券交易 所股票上市规则（试行）》《北京证券交易所上市公司持续监管指引第 1 号— —独立董事》《上市公司独立董事管理办法》等法律法规的规定和要求，谨慎、 认真、勤勉、独立地履行职责，持续关注公司规范运作、重大生产经营活动、财 务状况等，积极出席2024年度的相关会议，认真审议各项议案，对重大事项发 表了独立意见，维护了公司整体利益和全体股东尤其是中小股东的合法权益。现 就2024年度任职期间内履行职责情况汇报如下： 一、独立董事独立性情况 作为公司的独立董事，本人及本人直系亲属均不在公司或其附属企业担任 除独立董事之外的其他职务，也未在公司主要股东处担任任何职务；没有为公 司或其附属企业提供财务、法律、咨询等服务。除独立董事津贴外，没有从公 司及其主 ...

证券代码：430478 证券简称：峆一药业 公告编号：2025-032 2024 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承 担个别及连带法律责任。 本人杨模荣作为安徽峆一药业股份有限公司（以下简称"公司"）的独立 董事，在任职期间严格按照《公司法》《证券法》《公司章程》《北京证券交 易所股票上市规则（试行）》《北京证券交易所上市公司持续监管指引第1号— —独立董事》《上市公司独立董事管理办法》等法律法规的规定和要求，谨慎、 认真、勤勉、独立地履行职责，持续关注公司规范运作、重大生产经营活动、财 务状况等，积极出席 2024年度的相关会议，认真审议各项议案，对重大事项发 表了独立意见，维护了公司整体利益和全体股东尤其是中小股东的合法权益。现 就2024年度任职期间内履行职责情况汇报如下： 一、独立董事独立性情况 作为公司的独立董事，本人及本人直系亲属均不在公司或其附属企业担任 除独立董事之外的其他职务，也未在公司主要股东处担任任何职务；没有为公 司或其附属企业提供财务、法律、咨询等服务。除独立董事津贴外，没有从公 司及其主 ...

证券代码：430478 证券简称：峆一药业 公告编号：2025-031 2024 本公司及董事会全体成员保证公告内容的真实、准确和完整，没有虚假 记载、误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承 担个别及连带法律责任。 本人冯乙巳作为安徽峆一药业股份有限公司（以下简称"公司"）的独立 董事，在任职期间严格按照《公司法》《证券法》《公司章程》《北京证券交 易所股票上市规则（试行）》《北京证券交易所上市公司持续监管指引第1号— —独立董事》《上市公司独立董事管理办法》等法律法规的规定和要求，谨慎、 认真、勤勉、独立地履行职责，持续关注公司规范运作、重大生产经营活动、财 务状况等，积极出席 2024年度的相关会议，认真审议各项议案，对重大事项发 表了独立意见，维护了公司整体利益和全体股东尤其是中小股东的合法权益。现 就 2024年度任职期间内履行职责情况汇报如下： 一、独立董事独立性情况 作为公司的独立董事，本人及本人直系亲属均不在公司或其附属企业担任 除独立董事之外的其他职务，也未在公司主要股东处担任任何职务；没有为公 司或其附属企业提供财务、法律、咨询等服务。除独立董事津贴外，没有从公 司及其 ...

Share Repurchase and Equity Incentive - The company repurchased 514,900 shares, accounting for 0.9159% of the total share capital, for the purpose of an equity incentive plan[7]. - The 2024 equity incentive plan was approved, granting 514,900 restricted stocks at a price of 9.10 RMB per share to 37 individuals[9]. - The total amount paid for the share repurchase reached 6,001,548.78 CNY, accounting for 60.02% of the planned repurchase budget[132]. - The share repurchase plan aims to buy back between 375,000 and 625,000 shares, representing 0.67% to 1.11% of the total share capital[130]. - The company completed the 2024 equity incentive plan, granting 514,900 restricted shares at a price of 9.10 CNY per share[129]. Financial Performance - The company's operating revenue for 2024 reached ¥270,466,229.84, representing a year-over-year increase of 19.54% compared to ¥226,253,170.32 in 2023[28]. - The net profit attributable to shareholders for 2024 was ¥49,664,051.16, a 2.25% increase from ¥48,572,460.01 in 2023[28]. - The net profit after deducting non-recurring gains and losses increased by 35.18% to ¥45,245,491.34 in 2024 from ¥33,470,776.11 in 2023[28]. - Total assets at the end of 2024 amounted to ¥561,586,391.04, reflecting a growth of 5.29% from ¥533,395,393.75 in 2023[29]. - The company's total liabilities slightly decreased by 0.22% to ¥66,072,077.85 in 2024 from ¥66,215,014.88 in 2023[29]. - The weighted average return on equity based on net profit attributable to shareholders was 10.54% in 2024, down from 11.62% in 2023[28]. - The basic earnings per share for 2024 was ¥0.89, a decrease of 2.20% compared to ¥0.91 in 2023[28]. - The operating cash flow for 2024 was ¥41,462,010.43, showing a slight increase of 0.04% from ¥41,446,334.08 in 2023[29]. - The company's inventory turnover ratio improved to 1.89 in 2024 from 1.82 in 2023[30]. - The company's main business income increased by 20.20% to ¥269,420,880.33, compared to ¥224,150,865.51 in the previous year[68]. Research and Development - The company obtained several invention patents, including a low-impurity content synthesis method for vortioxetine and a preparation method for 4-amino-2,6-dichloropyridine[8]. - The company is recognized as a national high-tech enterprise, holding 13 invention patents and 19 utility model patents, indicating strong R&D capabilities[40]. - The company's R&D expenses grew by 29.69% to ¥20,513,979.77, reflecting increased investment in personnel and materials[67]. - The company has completed several R&D projects, including the optimization of production processes for various pharmaceutical intermediates, which are expected to enhance product quality and reduce costs[98][99]. - The company emphasizes technology innovation by increasing investment in R&D resources and closely monitoring industry trends to enhance product performance and functionality[117]. Market and Business Strategy - The company focuses on the research and sales of advanced pharmaceutical intermediates and raw materials[22]. - The company operates in the pharmaceutical manufacturing industry, specifically in the production of chemical drug raw materials[22]. - The company maintains a stable long-term cooperation with downstream clients, including well-known pharmaceutical companies in South Korea and Japan[40]. - The company’s business model remains unchanged, focusing on the R&D, production, and sales of high-end pharmaceutical intermediates and APIs[48]. - The company plans to expand its market presence through strategic investments and new product development initiatives[92]. Compliance and Governance - The company has a commitment to maintaining the accuracy and completeness of its financial reporting, as confirmed by its management[13]. - The company has no significant litigation or arbitration matters during the reporting period[127]. - There are no instances of shareholders or related parties occupying or transferring company funds or assets[127]. - The company has committed to avoid competition with its controlling shareholders and related parties[134]. - The company will ensure that all related transactions are conducted in accordance with market principles to protect the interests of all shareholders[156]. Shareholder and Management Information - The company has a total of 9 board members and 3 supervisors, with 4 senior management personnel[184]. - The total remuneration paid to directors, supervisors, and senior management during the reporting period amounted to CNY 2.9944 million[193]. - The company has a total of 29,131,485 shares held by directors, accounting for 51.82% of total shares[186]. - The company’s independent directors have not changed during the reporting period[189]. - The company’s major shareholders agreed that any profits from violations of commitments would be returned to the company, and they would not transfer their shares until the violations are rectified[162]. Employee and Workforce Development - The total number of employees increased from 424 to 439, with a net addition of 19 employees during the reporting period[197]. - The number of technical personnel rose from 76 to 91, reflecting a growth of 19.74%[197]. - The company has implemented a comprehensive employee training program to enhance professional skills and management levels[199]. - The company maintains a full labor contract system for all employees, ensuring compliance with social insurance and tax regulations[199]. - The number of employees with a doctoral degree increased from 2 to 4, representing a 100% increase[198].

一、主要会计数据和财务指标 | 报告期指标 | 2024年年报 | 2023年年报 | 本年比上年增减(%) | 2022年年报 | | --- | --- | --- | --- | --- | | 基本每股收益（元） | 0.8900 | 0.9100 | -2.2 | 1.8800 | | 每股净资产（元） | 8.61 | 11.35 | -24.14 | 10.29 | | 每股公积金(元) | 2.09 | 3.34 | -37.43 | 1.14 | | 每股未分配利润(元) | 5.19 | 6.53 | -20.52 | 7.65 | | 每股经营现金流(元) | - | - | - | - | | 营业收入(亿元) | 2.7 | 2.26 | 19.47 | 2.59 | | 净利润(亿元) | 0.5 | 0.49 | 2.04 | 0.57 | | 净资产收益率(%) | 10.54 | 11.62 | -9.29 | 19.83 | 前十大流通股东累计持有： 870.56万股，累计占流通股比： 25.83%，较上期变化： -23.36万股。 | 名称 持有数量(万股) | | 占总 ...

Investment Rating - The report assigns an "Accumulate" rating for the company for the first time [1]. Core Views - The company, Fangyi Pharmaceutical, focuses on high-value-added areas such as anti-allergy, anti-thrombotic, and antioxidant products, with a significant portion of its revenue coming from overseas markets [5][11]. - The company has established a CDMO (Contract Development and Manufacturing Organization) business, which is expected to drive future growth alongside its core pharmaceutical products [5][27]. - The financial forecast indicates steady revenue and profit growth, with projected revenues of 270.46 million, 324.56 million, and 398.62 million yuan for 2024, 2025, and 2026 respectively, reflecting growth rates of 19.54%, 20.00%, and 22.82% [4][5]. Summary by Sections Company Overview - Fangyi Pharmaceutical was founded in 2007 and is a leading domestic enterprise in specialty APIs and pharmaceutical intermediates, focusing on high-value areas [5][11]. - The company has a high concentration of ownership, with the largest shareholder, Dong Laishan, holding 39.20% of the shares, which enhances decision-making efficiency [1][5]. Product and Business Layout - The company specializes in high-end pharmaceutical intermediates and APIs, with products used in various therapeutic areas including anti-allergy and anti-thrombotic [27][28]. - The CDMO business, initiated in 2021, is showing promising results and is expected to become a new growth engine for the company [27][28]. Financial Performance - The company reported total revenue of 258.70 million yuan in 2022, with a projected increase to 270.46 million yuan in 2024, representing a growth rate of 19.54% [4][5]. - The net profit attributable to shareholders is expected to grow from 49.63 million yuan in 2024 to 74.74 million yuan in 2026, with growth rates of 2.17% and 22.11% respectively [4][5]. Industry Analysis - The global pharmaceutical market is projected to exceed 1.9 trillion USD by 2027, with China being a leading consumer market, driven by aging population and trends in innovative drug outsourcing [5][11]. - The CDMO market is expected to expand significantly, providing opportunities for companies with technological advantages and international presence [5][11].