Core Viewpoint - WuXi Biologics (02269.HK) is set to participate in the 44th Annual J.P. Morgan Healthcare Conference on January 14, 2024, where it will present updates on its business operations and financial performance [1] Group 1: Business Performance - The company reported a strong business and financial performance, with 209 new projects expected in 2025, bringing the total to 945 projects, including 74 in Phase III clinical trials and 25 CMO (Contract Manufacturing Organization) projects [1] - The research platform continues to show robust momentum, with record upfront and total payments in 2025, and new research contracts with potential milestone payments exceeding $4 billion [1] Group 2: Market Opportunities - Two-thirds of the new projects are focused on bispecific antibodies, multispecific antibodies, and ADCs (Antibody-Drug Conjugates), which are expected to drive innovation and open exciting market opportunities for the company [1] - The company completed 28 PPQ (Process Performance Qualification) projects in 2025, with 34 PPQ projects confirmed as of the announcement date in 2024, indicating a continuous increase in project activity [1] Group 3: Future Outlook - The company expresses confidence in maintaining growth momentum into 2026 and remains optimistic about its future prospects [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因倚賴該等內容而引致的任何損失承擔任何責任。 內幕消息 二零二六年度醫療健康大會簡報 本公告由WuXi Biologics (Cayman) Inc.藥明生物技術有限公司*（「本公司」）根據 香港聯合交易所有限公司證券上市規則（「上市規則」）第13.09條及香港法例第 571章《證券及期貨條例》第XIVA部項下內幕消息條文（定義見上市規則）而作出。 本公司將於二零二六年一月十四日（美國太平洋時間）出席第44屆年度摩根大 通醫療健康大會（「年度醫療健康大會」），會上將進行包含本公司業務營運的 若干資訊的簡報（「簡報」）。為確保本公司所有股東及潛在投資者能夠公平及 時地取得該等信息，本公司於本公告納入簡報全文。本公司股東及潛在投資者 務請注意，簡報可能包含前瞻性陳述，該等陳述就其性質而言存在風險及不確 定性，簡報中陳述的任何估計及未來建議均基於若干假設及估計以及管理層 僅根據當前可得資料作出的判斷。 – 1 – 誠如簡報中所披露，本集團業務及財務表現依 ...

Group 1 - BlackRock increased its holdings in Haier Smart Home, WuXi Biologics, Midea Group, and Bank of China on January 2, 2026 [1][3] - The shareholding percentage of WuXi Biologics increased from 5.32% to 6.14%, Midea Group from 5.15% to 6.75%, Bank of China from 5.98% to 6.11%, and Haier Smart Home from 7.72% to 8.34% [3] - Previously, on December 29, 2025, BlackRock had reduced its holdings in Midea Group from 7.03% to 5.16% and in Bank of China from 6.07% [3] Group 2 - Goldman Sachs released a report predicting that China's GDP growth in 2026 will exceed market expectations, recommending an overweight position in Chinese stocks [4][5] - The report anticipates a continuation of the bull market in Chinese stocks, with annual growth rates of 15% to 20% in 2026 and 2027, supported by earnings growth and valuation re-rating [5] - UBS Wealth Management expressed optimism for the Chinese market, highlighting advanced manufacturing and technological self-reliance as new growth engines, with a projected 37% earnings growth for the Hang Seng Tech Index in 2026 [5]

Market Overview - On January 7, Hong Kong's major stock indices showed a downward trend, with the Hang Seng Index closing at 26,458.95 points, down 0.94% [1] - The Hang Seng Tech Index also ended its previous week's gains, falling 1.49% to 5,738.52 points [1] - The market turnover exceeded HKD 276 billion, ending the upward momentum of the three major indices from the previous trading day [1] Sector Performance - The biopharmaceutical sector showed significant activity towards the end of the trading session, with notable gains in several stocks [1] - Rongchang Biopharmaceutical (09995.HK) rose over 12%, while 3SBio (01530.HK) and WuXi Biologics (02269.HK) closed with gains of over 7% and 5%, respectively [1] - Other sectors such as paper, non-ferrous metals, and coal also saw some individual stocks increase in value [1] Brokerages - In contrast, brokerage stocks faced pressure, with Guotai Junan International (01788.HK) declining over 5% [1] - Both China Merchants Securities (06099.HK) and Everbright Securities (06178.HK) also experienced declines of over 2% [1]

本文源自：金融界AI电报 据香港交易所披露，贝莱德对药明生物技术有限公司的多头持仓比例于2026年1月2日从5.32%增至 6.14%。 ...

Market Overview - The Hong Kong stock market experienced a downward trend, with the Hang Seng Index closing down 0.94% at 26,458.95 points and a total trading volume of HKD 2,761.34 million [1] - The Hang Seng China Enterprises Index fell by 1.14% to 9,138.75 points, while the Hang Seng Tech Index decreased by 1.49% to 5,738.52 points [1] - Zheshang International noted that the market fundamentals remain weak, with a decline in the funding environment, while policy focus is on new productivity and expanding domestic demand [1] Blue Chip Performance - WuXi Biologics (02269) led blue-chip stocks, rising 5.92% to HKD 36.12, contributing 11.87 points to the Hang Seng Index [2] - Other notable blue-chip performers included Innovent Biologics (01801) up 5.38% and WuXi AppTec (02359) up 4.91%, while Alibaba (09988) fell 3.25%, dragging the index down by 65.17 points [2] Sector Highlights Pharmaceutical Sector - The pharmaceutical sector continued its upward trend, with notable gains from Rongchang Biologics (09995) up 12.93% and Tigermed (03347) up 8.88% [3] - The National Medical Products Administration reported that 76 innovative drugs are expected to be approved by 2025, significantly surpassing the 48 approved in 2024, indicating a strong growth trajectory for the sector [4] Nickel Sector - Nickel stocks showed strong performance, with Xinjiang Xinxin Mining (03833) rising 12.28% and Zhongwei New Materials (02579) up 10% [4] - Nickel prices surged over 20% in the past two weeks, driven by supply constraints from Indonesia, which plans to reduce nickel mining quotas by 2026 [4] Paper Sector - The paper sector saw significant gains, with Nine Dragons Paper (02689) up 8.97% and Lee & Man Paper (02314) up 6.92% [5] - Several paper companies announced price increases, indicating a reduction in production pressure and a more favorable pricing environment [5] Coal Sector - Coal stocks generally rose, with Shougang Resources (00639) up 5.98% and China Qinfa (00866) up 5.92% [6] - The Dalian Commodity Exchange saw a surge in coking coal and coke futures, with expectations of improved supply-demand dynamics in 2026 [6] Optical Communication Sector - Optical communication stocks rebounded, with Yangtze Optical Fibre and Cable (06869) up 6.75% [6] - The sector is expected to benefit from advancements in AI technology and increased demand for high-performance components [7] Notable Stocks - Yadea Group Holdings (01585) announced a profit increase forecast, leading to a 4.63% rise in stock price [8] - JinkoSolar (06680) remained active with a 3.65% increase, driven by potential export restrictions on rare earth materials to Japan [9] - Jitu Express (01519) reached a new high, with a 3.39% increase, reporting significant growth in package volume [10] - GF Securities (01776) faced pressure, declining 4.09% after announcing a share placement and convertible bond issuance to raise funds for international business development [11]

Market Overview - The Hong Kong stock market indices experienced a collective adjustment, with the Hang Seng Index down by 0.94% to 26,458.95 points, the Hang Seng Tech Index down by 1.49% to 5,738.52 points, and the National Enterprises Index down by 1.14% to 9,138.75 points, ending a three-day upward trend [1] - Market sentiment is overly pessimistic, as indicated by a low turnover rate of 0.21% for the Hang Seng Index and a volatility index of 18.98, both at low percentiles for the year [1] Sector Performance Pharmaceuticals - Pharmaceutical stocks showed strong performance, particularly CRO and CDMO related stocks, with notable gains: Kelaiying up 8.92%, Tigermed up 8.88%, and WuXi Biologics up 5.92% [3][4] - The CRO and CDMO sectors are experiencing positive changes driven by both domestic and international demand, with an improving investment environment expected as overseas interest rate cuts begin in Q4 2024 [5] Metals - The metals sector, particularly nickel-related stocks, saw significant gains, with Lihua Resources up 4.92%, Rusal up 4.91%, and Jinke Permanent Magnet up 3.65% [6][7] - The price movements are influenced by Indonesia's announced reduction in nickel production, cutting its 2026 output target from 379 million tons in 2025 to 250 million tons, a decrease of 34% [6] Coal - Coal stocks also performed well, with Shougang Resources up 5.98%, China Qinfa up 5.92%, and Yanzhou Coal up 5.86% [9][10] - The coal industry is seeing an optimization in demand structure, with a projected annual electricity demand growth of about 5% over the next five years, supported by new manufacturing and digital computing needs [11] Automotive - Automotive stocks faced downward pressure, with BYD down 3.93%, NIO down 3.34%, and Xpeng down 2.19% [12][13] - Concerns stem from policy changes and weak demand, with predictions of a 7% decline in China's automotive market sales in 2026, marking the first annual negative growth since 2020 [12] Technology - Technology and internet stocks also underperformed, with Tencent Music down 5.50%, Alibaba down 3.25%, and Bilibili down 1.59% [15] - New regulatory measures aimed at strengthening oversight in the live-streaming e-commerce sector are impacting market sentiment [15] Individual Stock Movements - Nanhua Futures saw a rise of 5.07% as it is set to be included in the Hong Kong Stock Connect on January 19 [16] - ASMPT increased by 6.16%, driven by expectations of accelerated growth in the semiconductor industry due to a storage supercycle, with global storage market growth projected at 39.4% in 2026 [17]

Group 1 - The CRO (Contract Research Organization) sector in the Hong Kong stock market has shown strong performance, with notable gains across various companies [1] - Specifically, Kailaiying has increased by over 7%, while Tigermed and Zhaoyan Pharmaceutical have risen by over 5% [1] - Other companies such as WuXi AppTec and Kanglong Chemical have seen increases of over 3%, and WuXi Biologics and Kingsoft have gained over 2% [1]

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年12月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: WuXi Biologics (Cayman) Inc. 藥明生物技術有限公司*（於開曼群島註冊成立的有限公司）*僅供識別 呈交日期: 2026年1月6日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 02269 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 6,000,000,000 | USD | 0.000008333333 | USD | | 50,000 | | 增加 / 減少 (-) | | | 0 | | | USD | | 0 | | 本月底結存 | | | 6,000,000,000 | ...

Summary of Key Points from the Conference Call Industry Overview - The pharmaceutical sector is currently in a left-side layout phase after adjustments in 2025, with both institutional holdings and valuations positioned for upward elasticity, particularly in innovative drugs and their supply chains for 2026, benefiting from China's strengthening innovation competitiveness [1][4] - The recovery of the innovative industry chain is expected to continue, with CDMO orders and performance starting to recover from 2024, further improving in 2025 and expected to sustain into 2026 [1][9] Core Insights and Arguments - The driving forces behind the enhancement of China's innovation competitiveness include the successful implementation of business development (BD), overseas clinical progress, and commercialization, along with breakthroughs in new technologies such as XDC, dual antibodies, and small nucleic acids [5] - Investment opportunities in 2026 are concentrated in globally competitive assets, including innovative drugs, high-end manufacturing, and domestic demand-related sectors, particularly those with recovery logic [2] - The domestic demand recovery trend is clear, strengthening quarter by quarter in 2025, driven by high domestic innovation BD, a warming primary and secondary market, and an increase in IPOs in both A-shares and Hong Kong stocks [20] Notable Companies and Technologies - Key companies to watch include Innovent Biologics, Botai Biological Products, and Engen Biologics, which are core recommended assets due to their potential for significant data readouts and BD catalysts [6][10] - In the CRO sector, companies like Tigermed and Zhaoyan New Drug are expected to see performance turning points in 2026, supported by a recovery in domestic demand [3][21] - The CDMO sector is projected to continue its growth trajectory, with leading companies such as WuXi AppTec and Kelun Biotech expected to perform well due to increasing orders from overseas [22][23] Emerging Technologies and Investment Opportunities - Emerging technologies such as brain-computer interfaces and AI in pharmaceuticals are anticipated to bring new investment opportunities, with potential IPOs in these areas [12][29] - The central OTC sector is expected to see marginal recovery in 2026, with key companies like China Resources and Dong'e Ejiao being highlighted for their potential growth [13][30] Upcoming Catalysts and Key Events - Important upcoming events include the JPMorgan conference, which may provide data updates and BD changes, and significant data readouts expected in Q1 and April from major conferences [8][10] - The performance of companies in the first quarter of 2026 is anticipated to show significant elasticity and fundamental support, particularly in the CRO and innovative drug sectors [11][20] Conclusion - The pharmaceutical industry is positioned for a recovery phase with significant investment opportunities in innovative drugs, CDMO, and CRO sectors, driven by domestic demand recovery and technological advancements. Key companies and upcoming events will play a crucial role in shaping the market dynamics in 2026 [1][2][4][20]