Summary of the Conference Call for Xinwei Medical Industry and Company Overview - The conference call discusses Xinwei Medical's focus on **interventional brain-machine interfaces (BMIs)**, leveraging its existing technology in the **neurovascular field**. The company aims to address complex issues such as paralysis through advanced medical devices [2][5]. Key Points and Arguments 1. **Product Development Timeline**: - Xinwei Medical plans to complete product optimization by **2025**, conduct preclinical tests and animal experiments in **2026**, and initiate non-blind clinical trials by the end of **2026** to early **2027**. The entire process to finalize reports is expected to take **two to three years** [2][10]. 2. **Market Potential**: - Approximately **1.5 to 2 million** new stroke patients are reported annually in China, with a cumulative patient population exceeding **30 million**. This presents a significant demand for rehabilitation solutions [4][18]. 3. **Technical Advantages**: - The interventional approach offers a signal acquisition strength comparable to semi-invasive methods while maintaining lower infection risks and higher safety [3][5]. The existing technology from Xinwei Medical's thrombectomy stents facilitates easier entry into this market [5]. 4. **Clinical Trial Costs**: - The estimated cost for clinical trials is around **200,000 to 300,000 RMB** per patient, with a minimum of **100 patients** required for trials [12][13]. 5. **Regulatory and Reimbursement Landscape**: - Currently, there are no clear regulations for interventional BMIs in the national medical insurance directory. However, future alignment with interventional methods is anticipated as technology matures [14]. 6. **Commercialization Strategy**: - The product will be marketed through hospitals, requiring inclusion in reimbursement directories. The pricing strategy will consider production costs and potential reimbursement to alleviate patient financial burdens [15][19]. 7. **Competitive Landscape**: - Domestic competitors include **Zhonghua Brain Machine**, while international players like **Zenko** have initiated small-scale clinical studies. However, most companies are still in early development stages [2][7]. 8. **Technical Barriers**: - Significant challenges exist in hardware design, particularly for the electrode stent and subcutaneous signal transmission systems. Xinwei Medical's experience over the past nine years provides a competitive edge in overcoming these barriers [8][9]. 9. **Future Adaptations**: - The initial focus is on stroke patients, but there is potential for expanding indications based on technological advancements and market needs [16][17]. 10. **Surgical Considerations**: - The surgical procedure is complex, positioned between interventional and surgical methods, with neurosurgery being the most suitable field for these operations [21]. Additional Important Insights - The current prototype has a high domestic production rate, with core components being locally sourced, indicating a robust domestic supply chain [11]. - The industry is still in its nascent stages, with significant time required for product validation and market introduction, potentially taking **3 to 5 years** for mature products to emerge [25][26]. - The impact of national medical insurance policies on neuro-interventional products is evolving, with a focus on maintaining competitive pricing while ensuring quality care [27].

（股份代號：6609） 就2025年第二次臨時股東大會暫停辦理H股過戶登記 上海心瑋醫療科技股份有限公司（「本公司」）董事會謹此宣佈，為釐定有權出 席將於2025年8月29日（星期五）舉行的2025年第二次臨時股東大會（「臨時股東 大會」）並於會上投票的本公司H股（「H股」）持有人清單，本公司將於2025年7月 30日（星期三）至2025年8月29日（星期五）（包括首尾兩日）暫停辦理H股過戶登 記。於2025年8月29日（星期五）名列本公司H股股東名冊的H股股東將有權出席 臨時股東大會並於會上投票。於該期間內概不會登記任何股份轉讓。為符合資 格出席臨時股東大會並於會上投票，所有H股轉讓文件連同相關股票必須不遲 於2025年7月29日（星期二）下午四時三十分送達本公司的香港H股股份過戶登記 處香港中央證券登記有限公司，地址為香港灣仔皇后大道東183號合和中心17 樓1712–1716號舖，以作登記。一份載有擬於臨時股東大會提呈的決議案詳情 之通函，連同該大會的通告，將適時寄發予本公司股東。 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示， ...

Market Overview - The Hang Seng Index fell by 0.45%, down 107 points, closing at 23,808 points, while the Hang Seng Tech Index decreased by 0.15% [1] - Early trading volume in Hong Kong stocks reached HKD 109.5 billion [1] Stablecoin Regulation - The Hong Kong Monetary Authority plans to release guidelines for stablecoin regulations this month, aiming to issue licenses within the year [1] - Stocks related to stablecoins saw significant gains, with Guotai Junan International rising by 8.2%, ZhongAn Online increasing by 5.64%, and Yike rising over 9% [1] New Tea Beverage Market - A subsidy war in the takeaway market has ignited the new tea beverage sector, with Guming and Cha Baidao both rising over 9% [1] Digital Health Services - Health Road saw its stock rise over 9% as its controlling shareholder voluntarily extended the lock-up period, focusing on a digital health service platform [1] Gaming Industry - Morgan Stanley reported that Macau's gaming revenue in June increased by 19% year-on-year to MOP 21.1 billion, exceeding analyst predictions by 9% [1] - Gaming stocks continued their upward trend, with Amax Holdings up 3.7%, Melco International Development up 1.6%, and MGM China up 2.1% [1] Medical Device Sector - In response to China's reciprocal restrictions on EU medical devices, the National Medical Products Administration issued support for high-end medical devices [1] - Medical device stocks experienced broad gains, with Spring Medical up 1.86%, Yongsheng Medical up 7.27%, and Xinwei Medical-B up 5.5% [1] Company Developments - China Rare Earth Holdings plans to spin off its gold business for independent listing on the Hong Kong Stock Exchange, potentially seeking financing before the spin-off [2] - Jihong Co. saw its stock rise over 10%, with a projected over 55% year-on-year increase in net profit attributable to shareholders for the first half of the year [3] - H&H International Holdings is expected to see a decline in net profit by 45% to 65% for the first half of the year, resulting in a drop of over 6% in its stock price [4]

Market Overview - The US stock market was closed on July 4th for Independence Day [1] Hong Kong Stock Market Highlights - Yum China (09987) rose over 3% after announcing the establishment of an innovation fund to convert operational needs into practical applications [2] - H&H International Holdings (01112) fell over 7%, expecting a 45% to 65% decline in net profit for the first half of the year [2] - China Rare Earth Holdings (03788) surged nearly 9% as it plans to spin off its gold business for independent listing on the Hong Kong Stock Exchange, potentially seeking financing before the spin-off [2] - Health Road (02587) jumped over 18% as its controlling shareholder voluntarily extended the lock-up period, focusing on digital health services [2] - Smoore International (06969) increased over 5% with the launch of Glo Hilo in Japan, maintaining high profit margins [2] - Tencent Music (01698) rose nearly 3% as institutions noted that recent acquisition plans would enhance overall content supply [2] - Jihong Co., Ltd. (02603) surged over 7%, with a projected net profit increase of over 55% year-on-year for the first half [2] - Solar stocks collectively declined, with Xinyi Solar (00968) down 4.86%, Fuyao Glass (06865) down 3.88%, New Energy (01799) down 3.19%, and Xinyi Glass (00868) down 2.64% [2] Other Notable Movements - Kuaishou-W (01024) rose over 3% as it plans to launch a live streaming initiative across multiple cities to create a collaborative ecosystem [3] - Gold stocks faced pressure, with Shandong Gold (01787) down 5.09%, China Gold International (02099) down 3.44%, Lingbao Gold (03330) down 2.68%, and Chifeng Jilong Gold (06693) down 2.33% [3] - China Shipbuilding Defense (00317) increased over 3% after the approval of a merger and acquisition restructuring plan, optimizing resources in the shipbuilding industry [3] - Medical device stocks saw a broad increase, with Spring Medical (01858) up 6.36%, Yongsheng Medical (01612) up 7.27%, Xinwei Medical-B (06609) up 3.55%, and Microneuroscience (02172) up 1.12% [3] - Some stablecoin concept stocks rose, with Victory Securities (08540) up 6.9%, Guotai Junan International (01788) up 5.15%, Yika (09923) up 2.59%, and China Everbright Holdings (00165) up 1.96% [3] - SF Express City (09699) rose nearly 7% amid intensified competition in the food delivery sector, with expectations of increased order volume [3] - HSSP International (03626) fell over 20% after being named by the Hong Kong Securities and Futures Commission for high stock concentration [3] Strategic Partnerships and New Listings - Shengye (06069) opened nearly 15% higher after forming a strategic partnership with Stand Robot to enhance its robotics industry chain [4] - Beverage stocks opened high, with Cha Bai Dao (02555) up 15%, Nayuki's Tea (02150) up 9.87%, Gu Ming (01364) up 5.77%, Hu Shang Ayi (02589) up 2.99%, and Mixue Group (02097) up 2.92% [4] - FWD Group (01828) had a flat opening on its first day of listing, being a life insurance company under Li Zeqiang's control [4]

Group 1: Breakthrough in Visual Prosthetics - Chinese scientists have developed the world's first visual prosthetic with ultra-wide spectral response capabilities, enabling blind animals to regain visible light vision and expand their visual functions [1] - The retinal prosthetic, based on tellurium nanowire networks (TeNWNs), covers a spectral range from visible light (470nm) to near-infrared (1550nm), surpassing the natural human vision range of 380-780nm [1] - This technology avoids the risks associated with invasive brain surgeries and breaks the physiological limits of human vision, allowing users to perceive infrared light and accurately locate infrared light sources [1] Group 2: Growth of Brain-Computer Interface (BCI) Market - The global brain-computer interface technology is rapidly advancing, with significant attention from tech companies, medical institutions, academic research organizations, and government departments [2] - McKinsey predicts that the BCI medical application market could reach $40 billion by 2030 and $145 billion by 2040, with serious medical applications for central nervous system diseases estimated at $15 billion in 2030 and $85 billion in 2040 [2] - The domestic BCI companies are expected to gradually achieve commercialization due to technological innovations and favorable policies promoting industry development [2] Group 3: Related Companies in the BCI Sector - Micron Brain Science (02172) is a leading company in the domestic neuro-interventional medical device field, covering hemorrhagic stroke, atherosclerosis, and acute ischemic stroke, maintaining the top position in the domestic market share [3] - Xinwei Medical-B (06609) successfully completed animal trials for China's first interventional brain-computer interface, developed in collaboration with Nankai University's AI team [3] - Nanjing Panda Electronics (00553) is involved in the development of a multimodal human-computer interaction system based on BCI technology, which has been included in Jiangsu Province's key research and development plan [3]

董事會欣然宣佈，股東週年大會及臨時股東大會於2025年5月26日（星期一）上 午十時正假座中國上海市自由貿易試驗區臨港新片區正博路356號8幢4層思脉 德廳首先舉行股東週年大會，緊接股東週年大會結束後舉行臨時股東大會。股 東週年大會及臨時股東大會通告所載提呈決議案以投票表決方式獲通過。本 公司於香港的H股股份登記處香港中央證券登記有限公司獲委聘為於股東週年 大會及臨時股東大會上點票的監票人。 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不就因本公告全部或任何部分內容所產生或 因依賴該等內容而引致的任何損失承擔任何責任。 Shanghai HeartCare Medical Technology Corporation Limited 上 海 心 瑋 醫 療 科 技 股 份 有 限 公 司 （ 於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司 ） （股份代號：6609） 於2025年5月26日舉行的2024年度股東週年大會及臨時股東大會 投票表決結果 茲提述(i)上海心瑋醫療科技股份有限公司（「本公司」）日 ...

（ 於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司 ） （股份代號：6609） 於2025年5月26日舉行的2024年度股東週年大會及臨時股東大會 投票表決結果 茲提述(i)上海心瑋醫療科技股份有限公司（「本公司」）日期為2025年4月23日的 2024年度股東週年大會（「股東週年大會」）通告；(ii)日期為2025年5月7日的臨 時股東大會（「臨時股東大會」）通告；及(iii)本公司日期分別為2025年4月23日及 2025年5月7日的通函（「該等通函」）。除非另有指明，否則本公告所用詞彙與該 等通函所界定者具有相同涵義。 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不就因本公告全部或任何部分內容所產生或 因依賴該等內容而引致的任何損失承擔任何責任。 Shanghai HeartCare Medical Technology Corporation Limited 上 海 心 瑋 醫 療 科 技 股 份 有 限 公 司 董事會欣然宣佈，股東週年大會及臨時股東大會於2025年5月26日（星期一）上 午十 ...

Core Viewpoint - The spotlight in the global neurointervention field is shifting towards China, with significant innovations showcased by Xinwei Medical at the OCIN 2025 and WLNC conferences, highlighting the strength of "Made in China" products [1][3] Group 1: Product Innovations - Xinwei Medical introduced the first domestic intracranial aneurysm embolization assistive stent "Great Wall," which fills a technological gap in the domestic market and represents a leap in domestic neurointerventional devices [6] - The "Ruyi" coated mesh stent, as the first of its kind in China, utilizes a breakthrough phospholipid coating to enhance blood flow-directed therapy, significantly improving biocompatibility and treatment efficacy [7] - The CATCH cascade aspiration technology, based on a large-caliber aspiration catheter design, enhances thrombus removal efficiency and redefines surgical safety boundaries [8] Group 2: Market Performance - Xinwei Medical's revenue reached 277.9 million RMB in 2024, a 19.6% increase year-on-year, marking a historical high, while pre-tax losses narrowed significantly by 88.3% to 12 million RMB [11][12] - The company has seen a 45.5% year-on-year increase in sales of acute ischemic stroke treatment devices, indicating the effectiveness of its clinical demand-driven R&D strategy [13] Group 3: International Expansion - Xinwei Medical's overseas revenue surged by 684% to 8.4 million RMB in 2024, with Taiwan and India being key contributors, validating its international strategy [13] - The company has obtained CE or FDA certifications for several products and is actively pursuing registrations in over 40 countries, aiming to establish a global distribution network [14] Group 4: Industry Trends - The Chinese high-end medical device sector is experiencing a transformation driven by policy support, technological breakthroughs, and market expansion, reshaping the value growth curve for companies like Xinwei Medical [16][22] - The recent establishment of a high-end medical device industry alliance in Shenzhen aims to streamline the certification and registration process, enhancing the competitive landscape for domestic companies [18][19]

香港交易及結算所有限公司及香港聯合交易所有限公司對本通告的內容概不負責， 對其準確性或完整性亦不發表任何聲明，並明確表示，概不就因本通告全部或任何部 分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 Shanghai HeartCare Medical Technology Corporation Limited 上 海 心 瑋 醫 療 科 技 股 份 有 限 公 司 （ 於 中 華 人 立 限 公 司 ） 民 共 和 國 註 冊 成 的 股 份 有 （股份代號：6609） 董事長 臨時股東大會通告 王國輝 上海，2025年5月7日 – 1 – 1. 就2025年H股激勵計劃而言，各為一項獨立決議案： 1.1 審議及批准2025年H股激勵計劃；及 1.2 審議及批准計劃授權限額；及 2. 審議及批准授權董事會及其授權人士處理2025年H股激勵計劃有關事宜。 附註： 茲通告上海心瑋醫療科技股份有限公司（「本公司」）謹訂於2025年5月26日上午十時 三十分（或於緊隨本公司將於上午十時正召開及舉行的股東週年大會結束後）假座中國 上海市自由貿易試驗區臨港新片區正博路356號8幢4層思脉德廳舉行臨時股東大會 ...

此乃要件 請即處理 閣下如對本通函任何方面或將採取的行動有任何疑問，應諮詢 閣下之股票經紀或其他註冊證券交易商、銀行經 理、律師、專業會計師或其他獨立專業顧問。 閣下如已售出或轉讓名下所有上海心瑋醫療科技股份有限公司股份，應立即將本通函交予買主或承讓人，或經 手買賣或轉讓的銀行、股票經紀或其他代理商，以便轉交買主或承讓人。 香港交易及結算所有限公司及香港聯合交易所有限公司對本通函的內容概不負責，對其準確性或完整性亦不發 表任何聲明，並明確表示，概不就因本通函全部或任何部分內容所產生或因依賴該等內容而引致的任何損失承 擔任何責任。 本通函僅作參考用途，並不構成收購、購買或認購證券的邀約或邀請。 （股份代號：6609） (1)建議採納2025年H股激勵計劃 (2)建議授權董事會及 其授權人士處理2025年H股激勵計劃有關事宜 及 (3)臨時股東大會通告 本封面頁所用詞彙與本通函「釋義」一節所界定者具相同涵義。 董事會函件載於本通函第6至19頁。謹訂於2025年5月26日（星期一）上午十時三十分（或於緊隨股東週年大會結束後） 假座中國上海市自由貿易試驗區臨港新片區正博路356號8幢4層思脉德廳舉行臨時股東大會的通告 ...