智通财经APP讯，博安生物(06955)发布公告，配售事项于2025年8月14日落实完成。合共4800万股新股 份(相当于经配发及发行配售股份扩大的已发行股份总数约7.71%)已按配售价每股配售股份16.42港元配 售予不少于六名承配人。公司就配售事项收取的所得款项净额合共约为7.80亿港元。 ...

格隆汇8月14日丨博安生物(06955.HK)公告，公司宣布，配售事项于2025年8月14日落实完成。合共4800 万股新股份(相当于经配发及发行配售股份扩大已发行股份总数约7.71%)已按配售价每股配售股份16.42 港元配售予不少于六名承配人。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 就 因 本 公 告 的全部或任何部份內容而產生或因倚賴該等內容而引致的任何損失承擔任何 責 任。 本公告或其任何副本概不得直接或間接在美國或在刊發或派發本公告屬違法 的 任 何 其 他 司 法 權 區 內 刊 發 或 派 發。 本 公 告 僅 供 參 考，並 不 構 成 收 購、購 買 或 認 購 任 何 證 券 的 邀 請 或 要 約。 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6955） 完成根據一般授權配售新股份 茲提述 山東博安生物技術 股份有限公司（「本公司」）日期為2025年8月7日之公告 （「該公告」），內 容 有 關 配 售 本 公 司 之 新 股 份。除 本 公 告 另 有 界 定 者 外，本 公 告 所 用 詞 彙 與 該 公 告 所 界 定 者 具 相 同 涵 義。 – 1 – 完成根據一般授權配售新股份 本 公 司 宣 佈，配 售 事 項 於2025年8月14日 ...

Core Insights - The stock of Boan Biotech (06955) has increased by over 3%, currently trading at 18.88 HKD with a transaction volume of 313 million HKD [1] Group 1: Product Approval - Boan Biotech announced that its self-developed product, Bo You Ping® (Dulaglutide injection), has received approval from the National Medical Products Administration for market launch, aimed at blood sugar control in adult patients with type 2 diabetes [1] - Bo You Ping® is the world's first and currently the only approved biosimilar to Trulicity® (the English brand name), with no other domestic dulaglutide injections having entered the Biologics License Application (BLA) stage in China [1] Group 2: Commercialization and Collaboration - The commercialization of Bo You Ping® in mainland China will be conducted in collaboration with Shanghai Pharmaceuticals Holding Co., Ltd [1] Group 3: Technical Expertise - The development of dulaglutide, as a peptide-Fc fusion protein, involves complex processes, and the biosimilar's pharmaceutical (CMC) development is challenging [1] - The company possesses extensive technical expertise and experience in the CMC field, with an advanced process development platform that effectively controls critical quality attributes [1] - The innovative analytical platform has successfully developed control methods for key quality attributes, overcoming CMC technical challenges and facilitating the early approval of Bo You Ping® [1] Group 4: Clinical Trials - Beyond the Chinese market, Bo You Ping® has also been approved to conduct clinical trials in the United States [1]

Core Insights - The company Boan Biotech has received approval from the National Medical Products Administration for its self-developed drug, Boyouping (Dulaglutide Injection), aimed at blood sugar control in adult patients with type 2 diabetes [1] - Boyouping is a long-acting GLP-1 receptor agonist, and its commercialization in mainland China will be conducted in collaboration with Shanghai Pharmaceuticals [1] Distribution and Marketing - Shanghai Pharmaceuticals has a comprehensive distribution network covering 25 provinces and over 70,000 medical institutions, supported by nearly 1,000 professional marketing personnel [1] - The company will leverage its integrated marketing services and extensive market coverage to accelerate the distribution of Boyouping across hospitals, retail pharmacies, and DTP specialty pharmacies nationwide [1] Company Overview - Boan Biotech operates with an integrated "R&D-production-sales" model and is a local biopharmaceutical company [1] - The company has developed innovative antibody drugs based on three technology platforms: antibody-drug conjugate technology, bispecific T-cell engager technology, and fully human antibody transgenic mice and phage display technology [1] - In the biosimilar drug sector, the company has successfully launched four products [1] Financial Performance - For the year 2024, the company is projected to achieve a revenue of 730 million yuan, representing a year-on-year growth of 17.5% [1] - The net profit is expected to be 73.19 million yuan, marking a turnaround from previous losses [1]

Core Viewpoint - The company Boan Biotech (06955.HK) has received approval from the National Medical Products Administration for its self-developed product, Boyouping® (Dulaglutide Injection), aimed at blood sugar control in adult patients with type 2 diabetes. This product is the world's first and currently the only approved biosimilar to Trulicity® and is the only domestic dulaglutide injection that has not entered the Biologics License Application (BLA) stage in China [1]. Group 1 - Boan Biotech's Boyouping® is the first and only approved biosimilar to Trulicity® globally [1] - The product is specifically designed for blood sugar control in adult type 2 diabetes patients [1] - The commercialization of Boyouping® in mainland China will be conducted in collaboration with Shanghai Pharmaceuticals Holding Co., Ltd [1]

Core Viewpoint - The company has received approval from the National Medical Products Administration for its self-developed product, Boyouping® (Dulaglutide Injection), which is the first and only biosimilar to Trulicity® approved for the treatment of type 2 diabetes in adults in China [1][3] Group 1: Product Development and Approval - Boyouping® is a long-acting GLP-1 receptor agonist that can improve pancreatic beta-cell function and effectively lower blood glucose and HbA1c levels [1] - The product's development process adhered to biosimilar guidelines from China, the US, and the EU, confirming its overall similarity to Trulicity® in quality, efficacy, safety, and immunogenicity [3] - The company has overcome complex CMC challenges in developing the biosimilar, leveraging its advanced technical expertise and analysis platforms [2] Group 2: Market Potential and Commercialization - China has the highest number of diabetes patients globally, with projections of approximately 148 million adults with diabetes in 2024, expected to rise to 168 million by 2050 [4] - The GLP-1 drug market in China is projected to reach approximately 6.376 billion RMB in 2024, driven by the increasing patient demand [4] - The company has granted exclusive commercialization rights of Boyouping® in mainland China to Shanghai Pharmaceuticals, which has a vast distribution network covering over 70,000 medical institutions [4]

Core Insights - The company has received approval from the National Medical Products Administration for its self-developed product, Boyouping (Dulaglutide Injection), aimed at blood sugar control in adult patients with type 2 diabetes, making it the first and only approved biosimilar of Trulicity globally [1][3] - Boyouping is developed in collaboration with Shanghai Pharmaceuticals Holding Co., Ltd., which will handle its commercialization in mainland China [1][4] Company Development - The complexity of the manufacturing process for Dulaglutide, a peptide-Fc fusion protein, presents significant challenges in developing its biosimilar, but the company has leveraged its expertise in Chemistry, Manufacturing, and Controls (CMC) to overcome these hurdles [2] - The company has established advanced platforms for process development and quality control, enabling it to successfully navigate CMC technical challenges and achieve market approval for Boyouping [2] Clinical Research - The development of Boyouping adhered to the biosimilar guidelines of China, the US, and the EU, confirming its overall similarity to Trulicity through a series of rigorous studies [3] - Key clinical studies comparing Boyouping and Trulicity in China demonstrated that Boyouping effectively lowers blood sugar and weight, with no clinically significant differences in safety and immunogenicity [3] Market Potential - China has the highest number of diabetes patients globally, accounting for over 25% of the total, with projections indicating approximately 148 million adult diabetes patients in China and 589 million worldwide by 2024 [4] - The GLP-1 drug market in China is expected to reach approximately 6.376 billion RMB in 2024, driven by the increasing patient demand [4] - The global sales of Trulicity are projected to be around 5.25 billion USD in 2024, highlighting the significant market opportunity for Boyouping [4]

Core Viewpoint - The company announced that its self-developed product, BoYouPing® (Dulaglutide Injection), has received approval from the National Medical Products Administration for use in blood sugar control in adult patients with type 2 diabetes, marking it as the first and only approved biosimilar of Trulicity® globally [1][2]. Group 1: Product Approval and Market Position - BoYouPing® is the first and currently the only approved biosimilar of Trulicity® in the market, with no other domestic dulaglutide injections having entered the BLA stage in China [1]. - The commercialization of BoYouPing® in mainland China will be conducted in collaboration with Shanghai Pharmaceuticals Holding Co., Ltd [1]. Group 2: Product Characteristics and Benefits - Dulaglutide is a long-acting GLP-1 receptor agonist administered once a week, which improves pancreatic beta-cell function and effectively lowers blood sugar and HbA1c levels [1]. - In addition to good blood sugar control, dulaglutide offers multiple clinical benefits, including reducing major cardiovascular adverse events, weight loss, renal protection, and a low incidence of hypoglycemia and gastrointestinal adverse reactions [1]. - The weekly administration frequency enhances patient compliance by reducing medication inconvenience [1]. Group 3: Development and Clinical Research - The development of BoYouPing® adhered strictly to biosimilar guidelines from China, the US, and the EU, confirming its overall similarity to Trulicity® through a series of studies [3]. - Key clinical studies in China demonstrated that BoYouPing® can rapidly, stably, and persistently lower blood sugar while also reducing weight, showing consistent efficacy with Trulicity® in treating adult patients with type 2 diabetes [3]. - The results of the Phase I and Phase III clinical studies have been published in international academic journals, confirming the high similarity in quality, efficacy, safety, and immunogenicity between BoYouPing® and Trulicity® [3].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 就 因 本 公 告 的全部或任何部份內容而產生或因倚賴該等內容而引致的任何損失承擔任何 責 任。 Shandong Boan Biotechnology Co., Ltd. 山東博安生物技術股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6955） 自願性公告 度拉糖肽注射液 博優平®在中國獲批上市 山東博安生物技術 股份有限公司（「本公司」）董事會（「董事會」）宣 佈，本 公 司 自 主開發的 博優平® （度 拉 糖 肽 注 射 液）已 獲 得 國 家 藥 品 監 督 管 理 局 的 上 市 批 准， 用於成人2型 糖 尿 病 患 者 的 血 糖 控 制。該 產 品 是 全 球 首 個 且 當 前 唯 一 獲 批 上 市 的度易 達（英 文 商 品 名： ® Trulicity®）的 生 物 類 似 藥，國 內 尚 無 其 他 國 產 度 拉 糖 肽 注射液進入上市許可申請( ...