Financial Performance - In 2020, the company's operating revenue was approximately RMB 1.32 billion, a decrease of 4.90% compared to RMB 1.39 billion in 2019[25]. - The net profit attributable to shareholders of the listed company for 2020 was a loss of approximately RMB 126.86 million, a decline of 355.29% compared to a profit of RMB 49.69 million in 2019[25]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was a loss of approximately RMB 211.75 million, a decrease of 844.60% compared to a profit of RMB 28.44 million in 2019[25]. - Basic earnings per share for 2020 was -0.27 yuan, a decrease of 345.45% compared to 2019[26]. - Net profit attributable to shareholders decreased by 355.29% year-on-year, primarily due to a goodwill impairment loss of 265 million yuan[26]. - The company reported a cumulative undistributed profit of approximately RMB -227 million as of December 31, 2020, leading to no profit distribution to shareholders[6]. - The company has indicated that it will not implement capital reserve transfers to increase share capital or other forms of distribution due to the negative cumulative undistributed profit[6]. - The company reported a net profit margin of 0% for the years 2018, 2019, and 2020, indicating no profit distribution to shareholders[121]. Cash Flow and Investments - The net cash flow from operating activities for 2020 was approximately RMB 244.35 million, an increase of 1.19% compared to RMB 241.49 million in 2019[25]. - The company’s cash and cash equivalents increased by 67.85% compared to the beginning of the period, primarily due to the maturity of structured deposits[50]. - The company reported a significant improvement in cash flow from investment activities, with a net cash inflow of 308.09 million RMB, compared to a net outflow of 555.14 million RMB in the previous year[68]. - Cash flow from investing activities saw a significant increase of 155.50%, totaling ¥308,090,854.44, primarily due to the maturity of structured deposits[85]. - The company recognized an investment income of ¥43,300,143.33 from its subsidiary's investment in Aceso Biotech Venture Fund[87]. Business Operations and Strategy - The company operates in the "precision medicine" industry, focusing on cell detection preparation and storage, in vitro diagnostic materials, and gene testing services[36]. - The company has established cell resource banks across over 2/3 of the regions and 3/4 of the population in China, providing extensive coverage for stem cell detection and preparation services[36]. - The company has diversified its business model to include both newborn and adult cell storage services, catering to health-conscious adults and research institutions[36]. - The company aims to enhance its core businesses in cell storage and in vitro diagnostic reagents, focusing on expanding product lines and increasing R&D investment[111]. - The company will continue to enrich its cell storage offerings, including various types of stem cells and immune cells, while expanding its diagnostic testing products[111]. - The company is committed to promoting the clinical application of cell therapies and advancing related product development in collaboration with top-tier hospitals[111]. Research and Development - The company continued to invest in R&D, with R&D expenses increasing by 4.36% to 114.43 million RMB, reflecting a commitment to sustainable business growth[68]. - The company launched 18 self-developed projects in the in vitro diagnostic business, obtaining 19 registration certificates, indicating a strong focus on innovation[67]. - The number of R&D personnel increased to 174, accounting for 7.79% of the total workforce[83]. - The company completed 18 out of 42 major stem cell research and product development projects during the reporting period[84]. Market and Industry Trends - The domestic in vitro diagnostic industry is experiencing significant growth, driven by factors such as population aging and rising cancer incidence[43]. - The government has been actively promoting policies to support the development of the stem cell industry, indicating a favorable environment for growth[43]. - The "14th Five-Year Plan" emphasizes biotechnology as a strategic emerging industry, aiming to strengthen the bio-economy and optimize resource allocation for innovation[110]. Risk Factors and Compliance - The company has detailed risk factors that it may face in the report, which investors should review carefully[8]. - The company faces potential risks from industry policies, technology advancements, talent retention, and currency fluctuations, which could impact its operations and financial performance[117]. - The company has established a commitment to fair and transparent governance practices in all related transactions[139]. Environmental Responsibility - The company has implemented a self-monitoring plan for environmental emissions, ensuring compliance with pollution discharge standards[186]. - The company has established an emergency response plan for environmental incidents to minimize potential damage and ensure public safety[185]. - The company’s wastewater discharge met the standards with COD at 96 mg/L, significantly below the limit of 500 mg/L, and no exceedances reported[182]. Shareholder Relations and Commitments - The company has not distributed profits for 2019 and 2020 due to accumulated losses, with a net profit of 6.33 million yuan in 2020[120]. - The company has committed to not engaging in any business that competes with its subsidiaries, ensuring no direct or indirect competition[126]. - The company has established a commitment to avoid any illegal occupation of funds or assets, ensuring compliance with relevant laws and regulations[142].

Financial Performance - Net profit attributable to shareholders increased by 644.70% to CNY 45,553,625.54 year-on-year[12] - Operating revenue rose by 32.44% to CNY 366,683,497.82 compared to the same period last year[12] - Basic and diluted earnings per share both reached CNY 0.10, up 900.00% from CNY 0.01 in the previous year[12] - The significant increase in net profit was primarily due to the full waiver of the "PPP loan" approved by the SBA during the reporting period[18] - The net profit for Q1 2021 was ¥45,810,334.85, compared to a net profit of ¥5,889,050.84 in Q1 2020, representing a significant increase[45] - The comprehensive income total for Q1 2021 was ¥198,919,770.59, compared to ¥12,329,379.82 in Q1 2020, indicating strong growth[45] Cash Flow - Net cash flow from operating activities surged by 1,491.49% to CNY 49,151,166.35 year-on-year[12] - Cash flow from operating activities for Q1 2021 was ¥49,151,166.35, a significant increase from ¥3,088,365.70 in Q1 2020[55] - The net cash flow from operating activities for Q1 2021 was -8,926,947.28 RMB, an improvement from -20,879,853.57 RMB in Q1 2020[57] - Total cash inflow from operating activities was 58,829,999.63 RMB, compared to 46,385,745.41 RMB in the same period last year, representing a 26.8% increase[57] Assets and Liabilities - Total assets increased by 5.05% to CNY 5,126,007,661.74 compared to the end of the previous year[12] - Total liabilities reached ¥1,424,710,159.88, up from ¥1,377,191,804.90, marking a growth of around 3.44%[33] - Current liabilities rose to ¥1,324,843,654.87, compared to ¥1,300,015,430.19, indicating an increase of approximately 1.91%[31] - The company’s long-term borrowings decreased by 28.56% compared to the beginning of the year, due to the full exemption of previously applied loans[22] - The total assets as of Q1 2021 amounted to 4,879,569,536.17 RMB, a decrease from 4,935,894,374.98 RMB in the previous year[61] Shareholder Information - The number of shareholders at the end of the reporting period was 35,892[15] - The total equity attributable to shareholders increased to ¥3,595,012,040.38 from ¥3,396,348,979.10, reflecting a growth of about 5.85%[33] Expenses - Sales expenses increased by 47.93% year-on-year, mainly due to increased operating income during the reporting period[25] - Financial expenses decreased significantly by 1053.00% year-on-year, primarily due to increased interest income from deposits[25] - Research and development expenses for Q1 2021 were ¥29,769,464.49, slightly up from ¥27,897,123.35 in Q1 2020[44] Government Support - The company received government subsidies amounting to CNY 13,133,781.52, which are included in the current profit and loss[15] - Other income increased by 1690.68% year-on-year, mainly due to the full exemption of the "U.S. PPP Guarantee Program Loan" approved by the SBA[25] Investment Activities - Investment activities generated a net cash outflow of approximately 69.07 million, a decrease of 191.29% year-on-year, mainly due to structural deposits[28] - The company reported investment income losses of ¥2,564,779.24 in Q1 2021, compared to a gain of ¥2,314,299.99 in Q1 2020, indicating a downturn in investment performance[50] Changes in Financial Position - Other receivables increased by 142.83% to CNY 68,566,787.22 compared to the beginning of the year[19] - Other receivables rose significantly to ¥173,528,094.16 from ¥131,063,690.60, indicating an increase of approximately 32.5%[37] - Cash and cash equivalents decreased to ¥449,653,162.93 from ¥486,133,836.39, a decline of approximately 7.51%[33]

Financial Performance - The company reported operating revenue of RMB 969.37 million for the first nine months of 2020, a decrease of 3.58% compared to the same period last year[18]. - Net profit attributable to shareholders of the listed company reached RMB 133.10 million, an increase of 42.35% year-on-year[18]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was RMB 52.73 million, down 26.42% from the previous year[18]. - Total operating revenue for Q3 2020 was CNY 349,874,853.88, a 3% increase from CNY 337,027,026.17 in Q3 2019[53]. - Net profit for Q3 2020 reached CNY 52,393,785.04, compared to CNY 32,194,645.05 in Q3 2019, representing a 62.7% increase[57]. - The total comprehensive income for the first three quarters of 2020 was CNY 133,093,977.65, up from CNY 104,980,318.52 in the same period of 2019[57]. - The total comprehensive income attributable to the parent company's owners for the current period is CNY 23,534,610.23, compared to CNY 35,137,921.60 in the same period last year, reflecting a decrease of approximately 33.5%[60]. - The company reported a net loss of ¥450,885,928.09, an improvement from a loss of ¥583,988,877.39 in the previous period[44]. Assets and Liabilities - The total assets of the company at the end of the reporting period were RMB 5.13 billion, reflecting an increase of 4.85% compared to the end of the previous year[18]. - The company’s total equity attributable to shareholders was RMB 3.61 billion, an increase of 7.77% from the end of the previous year[18]. - Total current assets increased to ¥1,942,380,637.21 as of September 30, 2020, up from ¥1,905,868,878.58 on December 31, 2019, representing a growth of 1.9%[38]. - Total non-current assets reached ¥3,183,407,926.35, compared to ¥2,982,669,581.79, reflecting a growth of 6.7%[42]. - Total liabilities decreased slightly to ¥1,400,241,654.71 from ¥1,427,816,142.75, a reduction of 1.9%[44]. - The total cash and cash equivalents at the end of the period amounted to ¥1,010,203,787.47, compared to ¥990,675,535.57 at the end of the same period last year[71]. Cash Flow - The company generated a net cash flow from operating activities of RMB 151.62 million, a decrease of 3.24% compared to the same period last year[18]. - Net cash flow from investing activities increased by 394.26% compared to the same period last year, mainly due to the recovery of structured deposits[33]. - Net cash flow from financing activities decreased by 120.59% compared to the same period last year, primarily due to the absence of funds raised from a previous equity issuance[33]. - The net cash flow from operating activities for the first three quarters of 2020 was ¥151,618,311.80, a decrease from ¥156,699,220.70 in the same period of 2019[71]. - Cash inflow from investment activities reached ¥1,041,263,969.05, significantly higher than ¥16,764,934.16 in the previous year[71]. - The net cash flow from investment activities was ¥306,040,337.65, a recovery from a negative cash flow of ¥104,003,678.31 in the same period of 2019[71]. - The net cash flow from financing activities was -¥72,575,923.72, contrasting with a positive cash flow of ¥352,456,237.59 in 2019[71]. Shareholder Information - The number of shareholders at the end of the reporting period was 31,827[24]. - Shareholders' equity increased to ¥3,725,546,908.85 from ¥3,460,722,317.62, showing a growth of 7.7%[44]. - Basic earnings per share for the current period is CNY 0.11, an increase from CNY 0.07 in the previous quarter, while diluted earnings per share also stands at CNY 0.11[62]. Investment and Expenses - The company confirmed an investment income of RMB 50.07 million from its U.S. subsidiary's investment in Aceso Biotech Venture Fund, L.P.[27]. - Investment income increased by 527.13% compared to the same period last year, primarily due to the recognition of investment income from subsidiaries[32]. - Research and development expenses for Q3 2020 were CNY 38,377,550.11, a 42.6% increase from CNY 26,913,020.93 in Q3 2019[53]. - The company’s long-term investments in equity decreased to ¥213,491,419.30 from ¥220,661,067.04, a decline of 3.9%[38]. - The cash outflow for purchasing fixed assets and intangible assets was ¥75,168,226.98, an increase from ¥54,658,612.47 in the previous year[71]. Other Financial Metrics - The weighted average return on equity increased to 3.85%, up 0.67 percentage points from the previous year[18]. - Other comprehensive income increased by 326.86% compared to the beginning of the year, mainly due to the recognition of fair value changes of investments[31]. - The company reported a gross profit margin of approximately 13.2% for Q3 2020, compared to 11.5% in Q3 2019[53]. - The company experienced a foreign currency translation loss of CNY -15,800,337.66 in the current period, impacting overall comprehensive income[60]. Future Outlook - The company plans to continue expanding its market presence and investing in new technologies to drive future growth[53]. - The company has not reported any net profit from the merged entity prior to the merger, indicating a focus on future growth opportunities[62]. Accounting Standards - The company implemented new revenue and leasing standards starting January 1, 2020, which are not expected to significantly impact revenue recognition or net profit[76]. - The company did not make retrospective adjustments to prior period financial statements under the new standards[77].

Financial Performance - The company achieved operating revenue of RMB 619.50 million, a decrease of 7.31% compared to the same period last year[21]. - The net profit attributable to shareholders was RMB 81.33 million, an increase of 28.82% year-on-year[21]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was RMB 23.59 million, a decrease of 53.81% compared to the previous year[21]. - The net cash flow from operating activities was RMB 84.58 million, down 9.49% from the same period last year[21]. - The total assets at the end of the reporting period were RMB 5.11 billion, an increase of 4.52% from the end of the previous year[21]. - The net assets attributable to shareholders at the end of the reporting period were RMB 3.59 billion, an increase of 7.07% year-on-year[21]. - Basic earnings per share were RMB 0.17, up 21.43% from RMB 0.14 in the same period last year[22]. - The weighted average return on net assets was 2.37%, an increase of 0.13 percentage points compared to the previous year[22]. Investment and Acquisitions - The company recognized an investment income of RMB 50.07 million from its U.S. subsidiary and the acquisition of Zhongyuan Weikang[25]. - The company aims for global expansion through strategic investments and acquisitions, enhancing its operational efficiency and service capabilities[31]. - The company made a significant equity investment of ¥35 million in Heze Biotechnology, acquiring a 100% stake in stem cell storage technology services[61]. - The company reported a profit impact of ¥44.97 million from the sale of its entire stake in Hebecell Corp. to Aceso Biotech Venture Fund, L.P.[67]. - The company’s investment in Aceso Biotech Venture Fund, L.P. was ¥35.40 million, representing a 53.33% equity stake[63]. Research and Development - The company’s R&D expenses increased by 11.47% to ¥54.66 million from ¥49.03 million year-on-year, reflecting a commitment to innovation[47]. - The company has completed six clinical trial registrations for stem cell projects, showcasing its active involvement in advanced medical research[46]. - The company has initiated clinical trials for two new drugs in the immunotherapy sector, indicating progress in its precision treatment initiatives[46]. - The company has established a certain technological lead in cell preservation, separation, and extraction, with several patents obtained and pending, but must continuously invest in R&D to maintain its competitive edge[78]. Market Position and Strategy - The main business focuses on "precision medicine," covering cell detection, preparation, storage, and gene testing services, with significant contributions from stem cell applications[28]. - The company has established a comprehensive cell resource network, serving over 2/3 of the regions and 3/4 of the population in China, enhancing its market presence[31]. - The company emphasizes internal growth and integration of production, research, and sales to improve operational efficiency and innovation[33]. - The company has developed a digital marketing strategy leveraging new media platforms to enhance brand exposure and value[46]. - The company is actively promoting innovative marketing and product development strategies to ensure steady growth[34]. Financial Stability and Risks - The company's trading financial assets decreased by 25.18% to approximately 300.52 million yuan due to the maturity of structured deposits[38]. - Other equity investments increased by 54.00% to approximately 600.94 million yuan, primarily due to fair value changes from overseas investments[38]. - The company faces foreign exchange risks due to its global operations, with sales denominated in multiple currencies, which may impact future financial results[80]. - The company acknowledges the risk of talent shortages and turnover, implementing strategies such as equity incentives and performance-based compensation to align interests and retain key personnel[78]. - The company has committed to closely monitoring national policy developments and adjusting its business and product structures to mitigate potential impacts from regulatory changes[78]. Compliance and Governance - The company reported a significant focus on compliance with legal regulations and corporate governance, emphasizing the protection of minority shareholders' rights[96]. - The company guarantees that any necessary related party transactions will be conducted at fair market prices and in compliance with relevant laws and regulations[92]. - The company has established a framework to address any potential asset impairment issues related to the profit commitments made[89]. - The company has committed to avoiding any form of competition with its subsidiaries, ensuring no similar business activities are conducted that could harm shareholder interests[95]. Shareholder Information - The total number of common shareholders at the end of the reporting period was 32,801[127]. - The largest shareholder, Tianjin Development Zone Deyuan Investment Development Co., Ltd., held 84,064,327 shares, representing 17.96% of total shares[127]. - The total number of shares held by the top ten shareholders includes significant pledges, with Tianjin Development Zone Deyuan Investment having 81,233,260 shares pledged[127]. - The report indicates that there were no changes in the controlling shareholder or actual controller during the reporting period[133]. Legal Matters - The company has ongoing significant litigation regarding the transfer of state-owned land use rights, with a judgment requiring Singapore Huide Investment Holdings Co., Ltd. to repay CNY 71.21 million[104]. - In a separate case, the company is pursuing enforcement of a civil mediation agreement for a share transfer payment of CNY 30 million, of which only CNY 1 million has been received to date, leaving a balance of CNY 29 million unpaid[104].

证券代码：600645 证券简称：中源协和 公告编号：2020-038 中源协和细胞基因工程股份有限公司 关于举行"投资者网上集体接待日"活动公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大 遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： ●召开时间：2020年6月10日（星期三）15:00-16:30 ●召开方式：网络方式召开 一、说明会类型 中源协和细胞基因工程股份有限公司（以下简称"公司"）于2020年4月29 日发布了2019年年度报告。为便于广大投资者更深入全面地了解公司情况，公司 将在全景网以网络方式举行"投资者网上集体接待日"活动。 二、召开时间和方式 时间：2020年6月10日（星期三）15:00-16:30 方式：网络方式召开 三、公司出席人员 公司出席本次"投资者网上集体接待日"活动的人员有：公司董事、总经理 王勇先生，副总经理、董事会秘书杨新喆先生，财务总监王鹏先生（如有特殊情 况，出席人员会有调整）。 四、投资者参加方式 投资者可以登录" 全景·路演天下"（http://rs.p5w.net）参与交流。 欢迎广大投资者积极参 ...

Financial Performance - Net profit attributable to shareholders decreased by 80.17% year-on-year, amounting to CNY 6,117,082.04, primarily due to a decline in revenue caused by the pandemic [19]. - Operating revenue for the period was CNY 276,875,463.42, representing a decrease of 13.82% compared to the same period last year [12]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was CNY 2,343,106.78, a decrease of 92.33% year-on-year [12]. - Net profit for Q1 2020 was $5.89 million, a decline of 84.5% compared to $37.89 million in Q1 2019 [46]. - The total profit for Q1 2020 was $14.34 million, down 72.6% from $52.38 million in Q1 2019 [44]. - The total comprehensive income for the period was reported at -¥5,059,820.62, compared to -¥9,676,426.99 in the previous year, indicating an improvement in financial performance [55]. Cash Flow - The net cash flow from operating activities was CNY 3,088,365.70, down 39.01% from CNY 5,063,415.77 in the previous year [12]. - Net cash flow from operating activities decreased by 39.01% to 3,088,365.70 from 5,063,415.77, mainly due to reduced cash received from sales [26]. - In Q1 2020, the company reported a net cash flow from operating activities of ¥3,088,365.70, a decrease of 39.1% compared to ¥5,063,415.77 in Q1 2019 [55]. - Total cash inflow from operating activities was ¥305,374,759.16, down from ¥330,905,299.64 in the previous year, reflecting a decline of 7.7% [55]. - The net cash flow from financing activities improved by 26.58% to -13,757,596.89 from -18,738,301.82, as the repayment of loans decreased compared to the previous year [26]. - The net cash flow from financing activities was -4,367,079.95, compared to a positive cash flow of 529,894.61 in the previous period [59]. Assets and Liabilities - Total assets at the end of the reporting period were CNY 4,878,884,727.41, a decrease of 0.20% compared to the end of the previous year [12]. - Total liabilities amounted to approximately ¥1,405.83 billion, a decrease of 1.5% from ¥1,427.82 billion in the previous period [39]. - Non-current liabilities decreased to 1,330,679,579.61 from 1,350,003,407.69, reflecting a reduction in short-term borrowings [32]. - The total current assets were ¥662.05 million, a decrease of 1.3% from ¥670.43 million [38]. - The total assets decreased slightly to ¥4,197.23 billion from ¥4,209.13 billion, a decline of 0.3% [39]. Equity and Earnings - Basic earnings per share were CNY 0.01, a decrease of 85.71% compared to CNY 0.07 in the previous year [12]. - The weighted average return on equity decreased by 93.00 percentage points to 0.18% [12]. - The total equity attributable to shareholders reached ¥3,366.26 billion, an increase from ¥3,353.70 billion, reflecting a growth of 0.4% [39]. - The company’s total equity reached ¥3,473.05 billion, an increase from ¥3,460.72 billion, reflecting a growth of 0.4% [39]. Expenses - Employee compensation payable decreased by 48.29% to CNY 28,429,704.00, mainly due to the payment of 2019 annual performance bonuses [21]. - Research and development expenses increased to $27.90 million in Q1 2020, up 16.4% from $23.99 million in Q1 2019 [44]. - The company experienced a decrease in sales expenses to $59.72 million in Q1 2020 from $64.30 million in Q1 2019, a reduction of 7.9% [44]. - The company’s financial expenses decreased significantly to $248.86 thousand in Q1 2020 from $2.64 million in Q1 2019, a decline of 90.6% [44]. Investments - Investment income rose by 126.98% to 1,415,829.71 from -5,246,871.58, attributed to gains from the disposal of financial assets [23]. - The company reported an investment income of $1.42 million in Q1 2020, a significant improvement from a loss of $5.25 million in Q1 2019 [44]. - The company received ¥400,588,000.00 from investment recoveries in Q1 2020, indicating strong investment performance [55]. Accounting Standards - The company implemented new revenue and leasing standards starting January 1, 2020, which are not expected to significantly impact revenue recognition or financial metrics [59]. - The company did not make any retrospective adjustments to prior financial statements due to the new accounting standards [60]. - The company’s total assets and net assets are not expected to be significantly affected by the new accounting standards [59].

Financial Performance - The company's audited net profit for 2019 was -58.3992 million RMB, resulting in a cumulative undistributed profit of -233 million RMB as of December 31, 2019, leading to no profit distribution to shareholders [6]. - The total operating revenue for 2019 was approximately 1.387 billion RMB, representing a year-on-year increase of 5.02% compared to 2018 [22]. - The net profit attributable to shareholders of the listed company for 2019 was approximately 49.695 million RMB, a decrease of 16.13% from 2018 [22]. - The net cash flow generated from operating activities for 2019 was approximately 241.49 million RMB, an increase of 85.64% compared to 2018 [25]. - The total assets as of the end of 2019 were approximately 4.889 billion RMB, reflecting a year-on-year increase of 10.02% [25]. - The net assets attributable to shareholders of the listed company at the end of 2019 were approximately 3.354 billion RMB, a 20.96% increase from the end of 2018 [25]. - Basic earnings per share decreased by 26.67% to CNY 0.11 in 2019 compared to CNY 0.15 in 2018 [26]. - The company reported a net profit of approximately 28.438 million RMB after deducting non-recurring gains and losses, a significant improvement compared to a loss of approximately 262.48 million RMB in 2018 [22]. - The company reported a net profit of CNY 30,843,567.35 in Q1 2019, with a decline to -CNY 43,807,553.58 in Q4 2019 [29]. Revenue and Growth - The company achieved a revenue of 1.387 billion, representing a year-on-year growth of 5.02% [61]. - The company reported a total revenue of 109,648,855.89 CNY in R&D investments, accounting for 7.91% of total operating income [76]. - The company reported a significant increase in investment activities cash flow, with a net outflow of RMB 555,140,139.32, a change of -12,968.55% year-over-year [62]. - The company achieved a 66.96% increase in asset disposal income, amounting to 9,997,983.62 CNY, attributed to gains from patent technology disposals [75]. - The company reported a total guarantee amount of 2.17 billion RMB, which accounts for 6.47% of the company's net assets [199]. Research and Development - R&D investment accounted for 7.91% of the company's total revenue in 2019, with 180 R&D personnel [54]. - The company has established a comprehensive industry chain in precision medicine, covering cell storage, gene testing, and in vitro diagnostic reagents [48]. - The company has initiated 28 research projects in Shanghai Zhi Cheng Company, indicating a strong focus on expanding its research capabilities [77]. - The company has established a robust pipeline of diagnostic products, with a focus on immunohistochemistry and related methodologies [99]. - The company’s commitment to research and development is evident in its continuous introduction of new diagnostic reagents throughout the year [100]. Market and Industry Position - The company operates in the fields of cell detection, preparation, storage, and in vitro diagnostic reagents and instruments [35]. - The company aims to expand through both organic growth and strategic acquisitions globally [36]. - The domestic stem cell storage rate is currently below 1%, indicating significant growth potential, with the market size expected to exceed 30 billion RMB [39]. - The sales revenue of in vitro diagnostic reagents in China ranks among the top three in the medical device market, with immunodiagnostics and biochemical diagnostics dominating the market share since 2019 [43]. - The company has established a nationwide stem cell storage network with over 300,000 stored units, covering more than 2/3 of regions and 3/4 of the population in China [38]. Compliance and Governance - The company has established a quality safety management system to prevent potential incidents that could harm its reputation and financial performance [141]. - The company has made commitments to avoid engaging in competitive businesses and to adhere to share lock-up agreements related to major asset restructuring [155]. - The company will ensure compliance with relevant laws and regulations in all transactions to protect the interests of Zhongyuan Hehe and its minority shareholders [161]. - The company has not faced any penalties or corrective actions against its directors, supervisors, or senior management during the reporting period [187]. - The company has not engaged in any undisclosed major related party transactions during the reporting period [191]. Future Plans and Commitments - The company aims to achieve a revenue of 1.482 billion in 2020, focusing on cell storage and in vitro diagnostics as core businesses [137]. - The company plans to enhance its product line by expanding the types of stem cells stored, including hematopoietic stem cells and adipose-derived stem cells [134]. - The company intends to strengthen its online platform for the "life bank," improving user experience and service capabilities [137]. - The company will optimize its management system and organizational structure to improve operational efficiency and reduce costs [137]. - The company is committed to upgrading production processes, including the development of serum-free cell culture systems and automated diagnostic instruments [140].

Financial Performance - The company achieved operating revenue of RMB 1,005,353,917.75, representing a year-on-year increase of 3.50%[26] - The net profit attributable to shareholders was RMB 93,502,355.08, a decrease of 72.05% compared to the same period last year[26] - The net profit attributable to shareholders after deducting non-recurring gains and losses was RMB 71,669,807.52, an increase of 390.57% year-on-year[26] - Basic and diluted earnings per share were both RMB 0.21, down 75.00% from the previous year[18] - The major reason for the decline in net profit was the previous year's recognition of investment income of RMB 260 million from the disposal of equity stakes in certain companies[26] - The company reclassified the performance of Shanghai Aoyuan Medical Supplies Co., Ltd. from non-recurring to regular income, contributing to the increase in net profit after deducting non-recurring gains and losses[26] Assets and Liabilities - The total assets at the end of the reporting period were RMB 4,945,528,004.99, an increase of 11.30% from the end of the previous year[18] - The total liabilities amounted to ¥1,467,715,807.94, a marginal increase of 0.2% from ¥1,459,016,323.62[44] - The equity attributable to shareholders increased to ¥3,350,953,261.27 from ¥2,772,549,620.35, marking a growth of 21.0%[44] - The total non-current assets decreased slightly to ¥3,026,663,113.19 from ¥3,054,727,840.37, a decline of 0.9%[42] Cash Flow - The net cash flow from operating activities for the year-to-date was RMB 156,699,220.70, a significant increase of 197.11% compared to the same period last year[18] - Net cash flow from operating activities increased by 197.11% compared to the same period last year, mainly due to increased cash received from sales of goods and services[30] - Cash inflow from financing activities amounted to CNY 455,854,254.82, with a net cash flow of CNY 352,456,237.59, contrasting with a net outflow of -CNY 58,545,107.03 last year[77] - The total cash and cash equivalents at the end of the period reached CNY 990,675,535.57, up from CNY 528,418,247.77 in the previous year[77] Shareholder Information - The company reported a total of 37,349 shareholders at the end of the reporting period[21] Other Income and Expenses - Other income increased by 827.05% compared to the same period last year, primarily due to an increase in government subsidies[30] - R&D expenses increased to approximately ¥27 million in Q3 2019 from ¥20 million in Q3 2018, reflecting a growth of 35.5%[54] - The management expenses for Q3 2019 were approximately ¥8.08 million, down from ¥22.69 million in Q3 2018, representing a decrease of 64.4%[69] - The financial expenses for Q3 2019 were approximately ¥2.35 million, slightly up from ¥2.32 million in Q3 2018, indicating a marginal increase of 1.3%[69] Investment Activities - Cash outflow from investment activities totaled CNY 120,768,612.47, compared to CNY 283,907,544.68 in the previous year, resulting in a net cash flow from investment activities of -CNY 104,003,678.31[77] - Investment income decreased by 104.54% compared to the same period last year, mainly due to the disposal of equity stakes in certain companies in the previous year[30] Profitability - The company reported a net loss of ¥-537,712,431.24, an improvement from a loss of ¥-631,214,786.32 in the previous year[44] - The total operating profit for the first three quarters of 2019 was a loss of approximately ¥32.21 million, compared to a profit of ¥75.69 million in the same period of 2018, indicating a decline in profitability[69] - The company reported a net loss of approximately ¥5.62 million for Q3 2019, compared to a net loss of ¥6.67 million in Q3 2018, showing an improvement of 15.7%[69] Current Assets - As of September 30, 2019, the total current assets amounted to ¥1,918,864,891.80, an increase of 38.1% from ¥1,388,699,383.72 on December 31, 2018[38] - Accounts receivable rose to ¥461,871,120.97, up 11.2% from ¥415,330,742.05 in the previous year[38] - Cash received from sales and services was CNY 1,073,303,101.58, an increase from CNY 974,117,792.01 year-over-year[75]

Financial Performance - The company achieved operating revenue of RMB 668.33 million in the first half of 2019, representing a 3.81% increase compared to the same period last year[20]. - The net profit attributable to shareholders of the listed company was RMB 63.13 million, a decrease of 79.72% year-on-year[20]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was RMB 51.08 million, an increase of 507.64% compared to the previous year[20]. - The company's cash flow from operating activities was RMB 93.45 million, up 130.90% year-on-year[20]. - Basic earnings per share were RMB 0.14, down 82.72% from RMB 0.81 in the same period last year[23]. - The weighted average return on net assets decreased by 8.53 percentage points to 2.24%[23]. - The total assets of the company at the end of the reporting period were RMB 4.48 billion, an increase of 0.90% from the previous year[22]. - The net assets attributable to shareholders of the listed company were RMB 2.87 billion, up 3.56% from the previous year[22]. - The significant decline in net profit was primarily due to the previous year's gain from the disposal of equity in certain subsidiaries amounting to RMB 260 million[23]. - The increase in net profit after deducting non-recurring gains and losses was mainly attributed to the merger with Shanghai Aoyuan, which expanded the consolidation scope[23]. Business Operations - The company is engaged in cell detection preparation and storage, gene testing, and the research, production, and sales of in vitro diagnostic reagents and instruments, focusing on two core areas: cell storage and application, and in vitro diagnostic reagents[29]. - The company has established a nationwide cell resource library covering over 2/3 of regions and 3/4 of the population in China, providing services for umbilical cord blood stem cells and other cell types[32]. - The company completed the acquisition of Shanghai Aoyuan and its subsidiaries, forming a biopharmaceutical group with five major business segments, enhancing its market presence and operational capabilities[32]. - The newborn division focuses on the detection, preparation, and storage of umbilical cord blood stem cells, with a comprehensive service network across multiple provinces[32]. - The adult division provides immune cell and mesenchymal stem cell storage services, targeting health-conscious adults and research institutions[32]. - The gene division offers genomic medical testing services and reagent sales, utilizing both self-operated and agency marketing models to establish sales channels[32]. - The company’s proprietary biochemical diagnostic reagent brand "DENUO" includes a wide range of testing projects across nine major series, making it one of the most comprehensive manufacturers in the domestic market[32]. - The company has established 4 Life Science Museums nationwide to enhance public awareness of life science technologies, with over 1,800 applications of umbilical cord blood stem cells recorded by June 30, 2019[35]. - The launch of the new online health management platform "Lifebank" integrates sales, operations, and services for users of all ages, facilitating the collaborative sales of various health products[35]. Research and Development - The company emphasizes research and development, with over 157 R&D personnel, including 56 with master's degrees or higher, to maintain product competitiveness[43]. - The company reported a 16.78% increase in R&D expenses, totaling ¥49,033,456.58, reflecting its commitment to innovation and product development[49]. - The company is actively promoting public understanding of life sciences and has increased technical service support for umbilical cord blood stem cell public banks[35]. - Two new approved clinical research projects for stem cells were initiated, including a randomized controlled study for treating hepatitis B cirrhosis and a clinical study on liver regeneration in decompensated cirrhosis patients[35]. - By the end of June 2019, the number of registered stem cell clinical research institutions in China increased to 104, with 51 registered projects covering various diseases[35]. Market and Competitive Landscape - The company has a strong brand presence, being one of the earliest investors in biorepository projects in China, with over 18 years of safe operation and a leading market position in stem cell storage[40]. - The company has developed a comprehensive marketing network, combining direct sales and distributor channels to enhance competitiveness in the market[43]. - The Chinese biopharmaceutical industry continues to grow at a medium to high speed, supported by favorable government policies and an increasing number of enterprises[35]. - The company is expanding its market presence in Southeast Asia, targeting a 25% market share by the end of 2024[104]. Financial Position and Investments - The company reported a significant increase in other income by 229.07% to ¥1,017,441.70, mainly due to increased government subsidies[49]. - The investment income decreased by 104.64% to -¥11,673,542.84, primarily due to the previous year's gains from equity disposals[49]. - The company made an equity investment of 14,502.48 million yuan during the reporting period, an increase of 93.48% year-on-year[61]. - The company has completed the valuation and capital increase of CAR-T technology, valued at 66 million yuan, with an investment of 58 million yuan in Huyuan Biotechnology[124]. - The company holds a 21.642% stake in Huyuan Biotechnology after the capital increase[124]. Shareholder and Governance Matters - The company has committed to a net profit of no less than 65 million yuan for the year 2018, 79 million yuan for 2019, and 96 million yuan for 2020, with compensation obligations if these targets are not met[94]. - The lock-up period for shares acquired by Shenzhen Jiadao Investment Enterprise (Limited Partnership) is set for 36 months from the end of the issuance, starting from August 27, 2018, to August 26, 2021[93]. - The company’s actual controller and shareholders have committed not to engage in any business that competes with the company or its subsidiaries, both directly and indirectly[91]. - The company has established a long-term commitment to avoid related party transactions with companies under the actual control of De Yuan Investment Company, ensuring fair and reasonable pricing[97]. - The company has confirmed that it will not engage in similar business activities in new business areas that the company may enter in the future[96]. Legal and Compliance Issues - The company has no significant litigation or arbitration matters during the reporting period[115]. - The company has a history of legal disputes regarding land use rights, with a significant judgment requiring repayment of RMB 71.21 million[115]. - The company has reached a settlement in a dispute over a 67% equity transfer, with a payment of RMB 1 million due by December 31, 2018[115]. - The company has received a total of 2.1 million yuan related to the equity transfer, with 29 million yuan still outstanding from Guangzhou Dasai Company[118]. - As of the report date, the company has applied for enforcement of 60 million yuan against Guangzhou Dasai Company due to non-payment[118]. Financial Reporting Changes - The company implemented new financial instrument standards starting January 1, 2019, affecting accounting policies[138]. - Financial assets will be measured at amortized cost or fair value under the new standards[138]. - The company will not retrospectively adjust comparative statements for the previous year due to the new financial instrument standards[139]. Environmental and Social Responsibility - The company is committed to complying with environmental protection laws and regulations[133]. - The company has established management and emergency response plans to ensure compliance with waste discharge standards[133].

证券代码：600645 证券简称：中源协和 公告编号：2019-038 中源协和细胞基因工程股份有限公司 关于举行"投资者网上集体接待日"活动公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大 遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： ●召开时间：2019年5月9日（星期四）15：00-16:30 ●召开方式：网络方式召开 一、说明会类型 中源协和细胞基因工程股份有限公司（以下简称"公司"）于2019年4月30 日发布了2018年年度报告。为便于广大投资者更深入全面地了解公司情况，公司 将在全景网以网络方式举行"投资者网上集体接待日"活动。 二、召开时间和方式 时间：2019年5月9日（星期四）15：00-16:30 方式：网络方式召开 三、公司出席人员 公司出席本次"投资者网上集体接待日"活动的人员有：公司副董事长、总 经理李德福先生，董事、常务副总经理李旭先生，副总经理、董事会秘书杨新喆 先生，财务总监王鹏先生（如有特殊情况，出席人员会有调整）。 四、投资者参加方式 投资者可以登录" 全景·路演天下"（http://rs.p5w.net）参 ...