调价影响逐步恢复，全球布局不断深化 心脉医疗(688016) | [姓名table_Authors] | 电话 | 邮箱 | 证书编号 | | --- | --- | --- | --- | | 余文心(分析师) | 021-38676666 | yuwenxin@gtht.com | S0880525040111 | | 赵峻峰(分析师) | 0755-23976629 | zhaojunfeng@gtht.com | S0880519080017 | | 江珅(研究助理) | 021-23185638 | jiangshen@gtht.com | S0880125042234 | 投资要点： | [Table_Finance] 财务摘要(百万元) | 2023A | 2024A | 2025E | 2026E | 2027E | | --- | --- | --- | --- | --- | --- | | 营业总收入 | 1,187 | 1,206 | 1,512 | 1,875 | 2,301 | | (+/-)% | 32.4% | 1.6% | 25.4% | 24.0% | 22.7% | | ...

S1130525060003 gantanhuan gjzq.com.cn S1130514100001 zhaohc gjzq.com.cn S1130523080002 heguanzhou gjzq.com.cn S1130525070004 majudong gjzq.com.cn S1130525070006 wangbenben gjzq.com.cn 生物制品：司美格鲁肽 CKD 适应症获批，FLOW 研究显示可进一步降低 CKD&T2DM 患者的主要肾脏复合事件风险达 24%， 糖尿病并发症众多，建议持续关注 GLP-1 类药物在体重管理/T2DM 以外领域的适应症扩展。 中药：近年来，中药公司或通过 BD 引入新管线，或通过自主研发新药布局，积极寻求新增长点。我们继续推荐关注 创新药管线布局有望带来中药公司的估值提升机会，相关公司如在减重/降糖、银屑病等众多领域有新药管线布局的 康缘药业、干细胞研发管线持续推进的九芝堂等。 医疗器械：国内创新产品持续获批，龙头企业业绩有望逐步恢复。心脉医疗发布 2025 年半年度业绩预告，新产品 Talos 及 Fontus 入院家数及终端植入量均增长较快， ...

近日，心脉医疗发布2025年半年报业绩预告，营收与净利双降。 预告显示，心脉医疗预计2025年上半年实现营业收入7.08亿—7.87亿元，同比减少0—10.00%；归母净 利润为3.04亿—3.61亿元，同比减少10.52%—24.78%。 对于业绩下滑，公司在预告中表示，公司创新性产品Castor分支型主动脉覆膜支架及输送系统、Minos 腹主动脉覆膜支架及输送系统、ReewarmPTX药物球囊扩张导管持续发力，新产品Talos®直管型胸主动 脉覆膜支架系统及Fontus®分支型术中支架系统入院家数及终端植入量均增长较快，但考虑到2024年下 半年市场环境变化，公司产品价格及推广策略的调整因素，2025年上半年销售额增速及利润仍受到一定 影响。 连续四个季度负增长背后：销售模式遭集采冲击成长性堪忧？ 我们分季度看，今年二季度公司营收增速同比下滑4%至12%；归母净利润同比下滑15%至21%。事实 上，公司自去年三季度开始出现业绩增长失速情况。Wind数据显示，24年Q1、Q2营收增速均超过 25%，而24年Q3营收增速骤变负增长，大幅下滑31.65%。至此，公司已经连续四个季度负增长。 心脉医疗主要从事主动 ...

Core Viewpoint - The company expects a decline in revenue and net profit for the first half of 2025, primarily due to market environment changes and product price adjustments [2][3]. Performance Changes - The decline in performance is attributed to changes in the market environment in the second half of 2024 and adjustments in product pricing [3]. - Despite the challenges, innovative products such as Castor® and Minos® continue to show growth in hospital admissions and terminal implant volumes, although pricing and promotional strategy adjustments have impacted sales growth and profits [3]. New Product and R&D Progress - The company has made significant progress in new product development and market expansion, launching the next-generation Cratos® and receiving approval for the Tipspear® kit [5]. - Hector® has entered the special review process for innovative medical devices, marking the ninth product to enter the "green channel" for approval [5]. - The core product Castor® has received the 25th China Patent Gold Award for its patented technology [5]. Company Overview - Shanghai MicroPort CardioFlow Medtech Co., Ltd. was established in 2012 and focuses on the research, production, and sales of interventional medical devices for aortic, peripheral vascular, and tumor treatments [6]. - The company has a rich product line in the aortic and peripheral vascular interventional medical device field, including aortic stent systems and intraoperative stent systems [6][7]. - As of March 2025, the company's products are used in over 2,700 hospitals across China and have expanded to over 40 countries and regions [7].

Core Viewpoint - The domestic vascular intervention leader, Xinmai Medical, is facing significant challenges as it anticipates a decline in revenue and profit for the first half of 2025, marking the first instance of negative growth since its listing, attributed to market changes and product price adjustments [1][4]. Group 1: Financial Performance - Xinmai Medical expects revenue for the first half of 2025 to be between 708 million and 787 million yuan, a year-on-year decrease of 0% to 10% [1]. - The projected net profit attributable to shareholders is estimated to be between 304 million and 361 million yuan, reflecting a year-on-year decline of 10.52% to 24.78% [1]. - In the first half of 2024, the company maintained a revenue growth rate of 26.63% and a net profit growth rate of 44.06%, primarily driven by its core product, the Castor stent, which accounted for over 37% of revenue [4]. Group 2: Market and Regulatory Challenges - The National Healthcare Security Administration (NHSA) issued an inquiry regarding the high pricing of the Castor stent, which has a factory price of around 50,000 yuan but is sold to medical institutions for over 120,000 yuan [4]. - Following the inquiry, Xinmai Medical announced a price adjustment plan, resulting in a 40.42% price reduction for the Castor stent, with a new price cap of 71,500 yuan [4]. - The NHSA's focus on price rationality over innovation has made the previous high-margin pricing model unsustainable for Xinmai Medical [5]. Group 3: Strategic Adjustments and Risks - In response to market pressures, Xinmai Medical reduced its R&D investment by 34.9% in 2024, which may weaken its technological capabilities in the long term [6]. - The company’s overseas revenue contribution remains limited at 1.64 billion yuan, accounting for only 13.6% of total revenue, with the recent acquisition of Lombard Medical still in a loss-making state [6]. - The reliance on a single product for growth has exposed vulnerabilities, especially as the market undergoes significant restructuring and price reductions [5][6].

Core Viewpoint - The A-share market shows a mixed performance with the Shanghai Composite Index at 3503.55 points, slightly down by 0.46%, while the total trading volume reached 802.366 billion yuan, indicating active market participation [1]. Group 1: Market Performance - The Shanghai Composite Index is currently above the annual line, reflecting a stable market condition despite a minor decline [1]. - A total of 9 A-shares have surpassed the annual line today, with notable stocks showing significant deviation rates [1]. Group 2: Notable Stocks - Zhongdian Port (证券代: 001287) leads with a price increase of 9.99% and a deviation rate of 7.78% from the annual line, with the latest price at 20.26 yuan [1]. - Xinmai Medical (证券代: 688016) and Qianjiang Motorcycle (证券代: 000913) also show positive performance with deviation rates of 2.62% and 1.86%, respectively [1]. - Other stocks like Xueda Education (证券代: 000526) and Ziguang Guofeng (证券代: 000938) have lower deviation rates of 1.17% and 0.71%, indicating they have just crossed the annual line [1].

Policy Developments - The National Healthcare Security Administration reported that the basic medical insurance coverage rate in China remains stable at over 95%, with 1.32662 billion people insured by the end of 2024 [2] - The total income of the national basic medical insurance fund for 2024 is projected to be CNY 34,913.37 billion, while total expenditures are expected to be CNY 29,764.03 billion, resulting in a current balance of CNY 4,639.17 billion [2] - Since the establishment of the National Healthcare Security Administration in 2018, 835 new drugs have been added to the medical insurance drug list, with over 5,400 million CNY in sales from newly negotiated drugs between 2018 and 2024 [2] Drug and Device Approvals - Bayer's non-hormonal drug elinzanetant has been approved by the UK Medicines and Healthcare products Regulatory Agency for treating moderate to severe vasomotor symptoms related to menopause [5] - Innovent Biologics' new BCL2 inhibitor mesutoclax has received FDA approval to commence clinical trials for treating myeloid malignancies, including acute myeloid leukemia and myelodysplastic syndromes [6] - Tianyu Co., Ltd.'s subsidiary has passed the review for ezetimibe raw materials by the National Medical Products Administration, pending GMP compliance inspection results for market launch [7] Capital Market Activities - Innostellar Biotherapeutics has signed a ten-year exclusive promotion agreement with Golden Age Health for the commercialization of its gene therapy candidate LX101 in mainland China [9] Earnings Disclosures - Da'an Gene anticipates a net loss of CNY 140 million to 200 million for the first half of 2025 [11] - Huahai Pharmaceutical expects a net profit decline of 40% to 50% year-on-year, projecting a profit range of CNY 374 million to 449 million [12] - KingMed Diagnostics forecasts a net loss of CNY 95 million to 65 million for the first half of 2025, representing a significant year-on-year decline [13] - Xinmai Medical projects a net profit of CNY 304 million to 361 million for the first half of 2025, a decrease of 10.52% to 24.78% compared to the previous year [14] - Wantai Biological Pharmacy anticipates a net loss of CNY 130 million to 160 million for the first half of 2025 due to market pressures and policy adjustments [15] Industry Events - *ST Suwu has received a notice of administrative penalty from the China Securities Regulatory Commission for falsifying financial reports, which may lead to forced delisting [17] - This incident serves as a warning for the pharmaceutical industry to focus on genuine innovation and establish effective internal controls to mitigate risks associated with management [17] Shareholder Movements - Qihe Venture, a shareholder holding over 5% of Xuantai Pharmaceutical, plans to reduce its stake by up to 7 million shares, representing no more than 1.5441% of the company's total shares [19]

业绩简述 2025 年 7 月 14 日，公司发布 2025 年半年度业绩预告，预计 2025 上半年实现收入 7.08 亿元~7.87 亿元，同比-10%~0%；归母净利润 3.04 亿元~3.61 亿元，同比-25%~-11%。 从单 Q2 情况来看，预计实现收入 3.76 亿元~4.55 亿元，同比 -12%~+6%；归母净利润 1.74 亿元~2.31 亿元，同比-21%~+6%。 经营分析 同比增速受到价格调整影响，单季度环比实现快速恢复。国内市 场由于 24 年下半年市场环境变化，公司部分产品价格及推广策略 调整，部分产品毛利率降低，短期业绩出现一定压力。但公司 Castor分支型主动脉覆膜支架、Minos腹主动脉覆膜支架、Reewarm PTX 药物球囊扩张导管等核心产品持续发力，新产品 Talos 直管型 胸主动脉覆膜支架系统及Fontus分支型术中支架系统入院家数及 终端植入量均增长较快，Q2 单季度业绩环比实现快速恢复。 研发项目顺利推进，多款产品取得关键突破。公司创新研发的全 新一代 Cratos 分支型主动脉覆膜支架系统上市并实现临床植入； Tipspear 经颈静脉肝内穿刺套件获批上 ...

（二）业绩预告情况 经公司财务部门初步测算，预计 2025 年上半年度实现营业收入 70,845.72 万元到 78,717.47 万元，与上年同期（法定披露数据）相比，将减少 7,871.75 万 元到 0.00 万元，同比减少 10.00%到 0.00 %。 预计 2025 年上半年度实现归属于母公司所有者的净利润为 30,354.00 万元到 万元，同比减少 24.78%到 10.52%。 （三）本次业绩预告未经注册会计师审计。 二、上年同期业绩情况 润 40,352.36 万元。 证券代码：688016 证券简称：心脉医疗 公告编号：2025-029 上海微创心脉医疗科技（集团）股份有限公司 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、本期业绩预告情况 （一）业绩预告期间 支型主动脉覆膜支架系统上市并实现临床植入；Tipspear®经颈静脉肝内穿刺套 件获批上市。Hector®胸主动脉多分支覆膜支架系统正式获批进入国家药品监督 管理局（NMPA）创新医疗器械特别审查程序，该产品用于微创伤介入治疗累及 主动脉 ...

证券代码：688016 证券简称：心脉医疗 公告编号：2025-029 上海微创心脉医疗科技（集团）股份有限公司 2025 年半年度业绩预告的自愿性披露公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、本期业绩预告情况 （一）业绩预告期间 2025 年 1 月 1 日至 2025 年 6 月 30 日。 （二）业绩预告情况 经公司财务部门初步测算，预计 2025 年上半年度实现营业收入 70,845.72 万元到 78,717.47 万元，与上年同期（法定披露数据）相比，将减少 7,871.75 万 元到 0.00 万元，同比减少 10.00%到 0.00 %。 预计2025年上半年度实现归属于母公司所有者的净利润为30,354.00万元到 36,109.00万元，与上年同期（法定披露数据）相比，将减少9,998.36万元到4,243.36 万元，同比减少 24.78%到 10.52%。 （三）本次业绩预告未经注册会计师审计。 二、上年同期业绩情况 2024 年上半年度实现营业收入 78,717.47 万元，归属于 ...