格隆汇10月23日丨热景生物(688068.SH)公布，公司前三季度实现营业收入3.1亿元，同比下降19.80%； 归属于上市公司股东的净利润-1.09亿元；基本每股收益-1.23元。 ...

Core Insights - The report highlights the performance of the Changcheng Pharmaceutical Industry Selected Mixed A Fund, which has shown significant growth in equity scale, particularly in the technology sector, despite recent market adjustments [1][3]. Performance Analysis - As of October 22, 2025, the fund's unit net value is 1.7983, with a cumulative return of 79.83% since its establishment on October 22, 2024, and a year-to-date increase of 88.34% [1][3]. - The fund has experienced a notable decline of -8.81% over the past month and -14.29% over the last three months, indicating challenges faced by the pharmaceutical sector, especially in the innovative drug field during the third quarter [3][4]. Portfolio Composition - The top ten holdings of the fund have a combined market value of 1.313 billion, heavily concentrated in the innovative drug sector, which differs from the asset allocation logic of technology funds [4]. - The top three holdings include Innovent Biologics, 3SBio, and Hotgen Biotech, with a clear focus on biotechnology and innovative pharmaceutical companies [5]. Investment Strategy - The fund manager, Liang Furui, noted that the A/H market saw multiple sectors rise, primarily driven by technology and precious metals, with an average daily trading volume in the A-share market exceeding 2 trillion [5]. - Despite the strong performance of technology sectors, innovative drugs have entered a correction phase due to significant gains in the first half of the year and negative impacts from TMT-focused capital outflows [5][6]. - Liang Furui emphasized that many innovative drug stocks are now highly cost-effective, suggesting a shift towards selecting individual stocks with genuine competitive advantages as the sector moves into an "individual alpha phase" [6]. Future Outlook - The focus will be on increasing the weight of stocks with global competitiveness and scarcity in core pipelines, balancing long-term potential, drug certainty, and international market viability [6].

10月23日，热景生物跌5.11%，截至发稿，报163.36元/股，成交5.69亿元，换手率3.48%，总市值151.45 亿元。热景生物股价已经连续3天下跌，区间累计跌幅5.55%。 数据显示，华富基金旗下1只基金重仓热景生物。华富健康文娱灵活配置混合A（001563）二季度减持 1.8万股，持有股数3.2万股，占基金净值比例为6.06%，位居第五大重仓股。根据测算，今日浮亏损失 约28.16万元。连续3天下跌期间浮亏损失32.38万元。 风险提示：市场有风险，投资需谨慎。本文为AI大模型自动发布，任何在本文出现的信息（包括但不 限于个股、评论、预测、图表、指标、理论、任何形式的表述等）均只作为参考，不构成个人投资建 议。 资料显示，北京热景生物技术股份有限公司位于北京市大兴区中关村科技园区大兴生物医药产业基地庆 丰西路55号院7号楼1-5层，成立日期2005年6月23日，上市日期2019年9月30日，公司主营业务涉及研 发、生产和销售体外诊断试剂及仪器。主营业务收入构成为：检测试剂70.87%，检测仪器19.79%，其 他8.17%，生物原料1.17%。 责任编辑：小浪快报 从基金十大重仓股角度 华富健康 ...

Investment Rating - The report assigns a "Buy" rating for the company, marking its first coverage [1]. Core Insights - The company is focusing on innovative treatments in the cardiovascular field, particularly the potential of SGC001 as a first-in-class (FIC) drug for acute myocardial infarction (AMI) [7][31]. - The company has a diversified pipeline with multiple subsidiaries engaged in innovative drug development, including SGC001, which has received IND approvals in both China and the U.S. [7][12]. - The in vitro diagnostics (IVD) business provides a stable revenue base, with a comprehensive product layout and leading-edge technology platforms [7][12]. Summary by Sections 1. Company Overview - The company, established in 2005 and listed on the Shanghai Stock Exchange in 2019, has been actively developing innovative diagnostic technologies and drug pipelines through its subsidiaries [12][15]. 2. Innovative Drug Development - SGC001 is highlighted as a significant product for AMI treatment, with promising clinical results and a strong market need for new therapies [7][31]. - The company is expanding its drug pipeline to include various therapeutic areas, including oncology and neurodegenerative diseases, leveraging its subsidiaries for differentiated drug development [7][31]. 3. IVD Business - The IVD segment is crucial for the company's revenue, with ongoing development in various diagnostic technologies and health initiatives aimed at improving public health [7][12]. - The company has established several core technology platforms that support its IVD product offerings, enhancing its competitive position in the market [7][12]. 4. Financial Projections - The company is projected to achieve revenues of 5.42 billion, 5.97 billion, and 6.67 billion yuan from 2025 to 2027, with a gradual return to profitability expected by 2027 [1][7]. - The report anticipates that the combined value of the IVD business and innovative drug pipeline could reach approximately 48 billion yuan [7][12].

Core Viewpoint - Beijing Hotgen Biotech Co., Ltd. announced that its affiliate, ShunJing Biopharmaceutical Technology Co., Ltd., has achieved positive preliminary results in the Phase Ib clinical trial of the innovative drug SGC001, which is aimed at treating acute myocardial infarction [1][2]. Clinical Progress - The Phase Ib clinical trial of SGC001 has been completed, showing good safety and tolerability in patients with anterior ST-segment elevation myocardial infarction (STEMI) [1]. - No grade 3 or higher adverse events were reported across low (300 mg), medium (600 mg), and high (900 mg) dosage groups, indicating a strong safety profile [1][2]. - Pharmacokinetic analysis revealed that the median Tmax for SGC001 ranged from 1.30 to 4.07 hours, with a half-life (t1/2) of approximately 8 to 11 days [2]. Preliminary Efficacy Results - Initial efficacy results indicated that SGC001 at 600 mg and 900 mg doses showed a trend towards myocardial protection compared to the placebo group, with median reductions in myocardial infarction area percentages of 20.5% and 38.1%, respectively [2]. - The time required for high-sensitivity cardiac troponin I (hsTnI) and high-sensitivity C-reactive protein (hs-CRP) to return to normal levels was shorter in the treatment groups compared to the placebo [2]. Drug Overview - SGC001 is a monoclonal antibody developed for emergency treatment of acute myocardial infarction, specifically targeting anterior STEMI [3]. - The drug has received clinical trial approvals from both the U.S. FDA and China's National Medical Products Administration (NMPA), and it was granted Fast Track Designation by the FDA in March 2025 [3]. - The project has also received support from Beijing's Science and Technology Program and is recognized as an innovative pharmaceutical product [3].

Core Insights - The article highlights the significant performance of certain funds in the third quarter, particularly the "Yongying Technology Smart Selection" fund, which achieved a remarkable 194% increase, making it the top-performing fund of the year [1][2] - The report indicates a substantial growth in fund size, with "Yongying Technology Smart Selection" increasing from 1.166 billion to 11.521 billion yuan, nearly a ninefold increase in a single quarter [2] - The article also discusses the ongoing optimism in the innovative pharmaceutical sector, with funds like "Great Wall Pharmaceutical Industry Selection" showing over 100% growth [1][4] Fund Performance - "Yongying Technology Smart Selection" fund's top holdings include leading optical module stocks such as "Yizhongtian" (Xinyi Sheng, 300502), Zhongji Xuchuang (300308), and Tianfu Communication (300394), which significantly contributed to its net value [2] - The fund's share count surged from 700 million to 3.466 billion, resulting in a profit of 4.715 billion yuan for investors in the third quarter [2] - The "Great Wall Pharmaceutical Industry Selection" fund also saw its size grow from 1.132 billion to 1.790 billion yuan, with a share increase from 678 million to 932 million [5] Sector Insights - The global cloud computing industry remains a focal point, with AI model valuations increasing and a notable 100% quarter-on-quarter growth in token numbers [3] - The innovative pharmaceutical sector continues to attract attention, with funds maintaining high stock positions despite recent market adjustments [6][8] - The article suggests that the technology and pharmaceutical sectors may still have upward potential, although careful stock selection is advised [8] Future Outlook - The article indicates that the technology sector, particularly AI and cloud computing, is expected to see increased investment, with potential for new opportunities in the industry chain [9] - The innovative pharmaceutical sector is projected to strengthen its global competitiveness, supported by upcoming industry conferences and positive data trends [8] - The article emphasizes the importance of not solely relying on past performance to predict future outcomes in the cloud computing sector, highlighting the need for caution [9]

（文章来源：证券日报） 证券日报网讯 10月22日晚间，热景生物发布公告称，近日，公司收到参股公司北京舜景生物医药技术 有限公司关于自主研制的创新药SGC001注射液Ib期临床研究获得了积极的初步结果的汇报。 ...

Group 1 - Sanwang Communication plans to repurchase shares worth 20-40 million yuan for employee stock incentive plans [1] - Ankrui reported a net profit of 192 million yuan for the first three quarters, a year-on-year increase of 21.31% [1] - Taishan Petroleum's net profit for the first three quarters reached 113 million yuan, up 112.32% year-on-year [1] - Zhejiang Xiantong achieved a net profit of 152 million yuan for the first three quarters, a 17.4% increase year-on-year [1] Group 2 - Xuanji Information reported a net loss of 173 million yuan for the first three quarters [1] - Mailande's net profit slightly decreased by 0.07% to 96 million yuan for the first three quarters [1] - Tengjing Technology's subsidiary received a sales order worth 87.61 million yuan [1] Group 3 - Hotgen Biotech's affiliate achieved positive results in Phase Ib clinical trials for the innovative drug SGC001 [1] - Zhongyan Dadi won a bid for a sports project in Beijing worth 74.04 million yuan [1] - Henghui Security's net profit decreased by 12.85% to 81.98 million yuan for the first three quarters [1] Group 4 - Xiongdi Technology's net profit increased by 71.16% to 18.38 million yuan for the first three quarters [1] - Meilixin reported a net loss of 215 million yuan for the first three quarters [1] - Haichen Pharmaceutical's net profit grew by 16.22% to 32.68 million yuan for the first three quarters [1] Group 5 - Qiaoyuan Co. reported a net profit of 181 million yuan for the first three quarters, a 40.54% increase year-on-year [1] - Fuda Co. achieved a net profit of 221 million yuan for the first three quarters, up 83.27% year-on-year [1] - Xianggang Technology's net profit surged by 186.19% to 95.47 million yuan for the first three quarters [1] Group 6 - ST Nanchuan received a restriction order from the court due to a financial dispute [1] - Changyou Technology announced the dismissal of two vice presidents [1] - Haoyuan Automotive received a project confirmation for an automatic parking system worth 576 million yuan [1] Group 7 - Jiuzhou Biotech obtained a medical device registration certificate for a diagnostic kit [1] - Shihua Machinery signed an investment intention letter for a subsidiary's capital increase [1] - Zhuhai Mian Group plans to transfer 100% equity of Gree Real Estate [1] Group 8 - Dalian Heavy Industry reported a net profit of 490 million yuan for the first three quarters, a 23.97% increase year-on-year [1] - Haimeng Data reported a net loss of 75.43 million yuan for the first three quarters [1] - Feilong Co. achieved a net profit of 287 million yuan for the first three quarters, a 7.54% increase year-on-year [1] Group 9 - Kaipu Testing reported a net profit of 57.84 million yuan for the first three quarters, a 3.34% increase year-on-year [1] - Ganyue Express signed a strategic cooperation agreement with a major energy company [1] - Tuoshan Heavy Industry's controlling shareholder plans to reduce its stake by 2.82% [1] Group 10 - Yiatong's shareholder plans to reduce its stake by 1% [1] - Weishi Electronics reported a net profit of 24.29 million yuan for the first three quarters, a 22.59% decrease year-on-year [1] - Shensi Electronics won a bid for a data space construction project worth 161 million yuan [1] Group 11 - Xiechuang Data plans to purchase server assets worth up to 4 billion yuan [1] - Shandong Express's controlling shareholder plans to transfer 7% of its shares [1] - ST Huapeng's subsidiary received a government subsidy of 4.65 million yuan [1] Group 12 - Jieqiang Equipment's shareholder plans to reduce its stake by 1% [1] - China Jushi reported a net profit of 2.568 billion yuan for the first three quarters, a 67.51% increase year-on-year [1] - ST Fanli reported a net loss of 44.78 million yuan for the first three quarters [1] Group 13 - Xiyu Tourism reported a net profit of 98.58 million yuan for the first three quarters, a 14.51% decrease year-on-year [1] - Abison reported a net profit of 185 million yuan for the first three quarters, a 57.33% increase year-on-year [1] - Huayan Precision reported a net profit of 70.76 million yuan for the first three quarters, a 31.07% increase year-on-year [1] Group 14 - Jiangling Motors reported a net profit of 74.9 million yuan for the first three quarters, a 35.76% decrease year-on-year [1]

Group 1: Fund Performance and Holdings - The performance of the "Champion Fund" Yongying Technology Smart Selection has seen a remarkable increase, with a year-to-date return of nearly 195% and a net asset value growth of 234% since its inception [2][3][9] - The fund's scale surged nearly tenfold in the third quarter, growing from 1.166 billion to 11.521 billion yuan, with the number of shares increasing from 700 million to 3.466 billion [5][9] - The fund maintains a high stock position, with over 91% in equities, focusing heavily on the cloud computing sector [2][3] Group 2: Key Holdings in Cloud Computing - The top three holdings of Yongying Technology Smart Selection include Xinyi Technology, Zhongji Xuchuang, and Tianfu Communication, each with a market value exceeding 1 billion yuan [3][2] - Significant increases in holdings were observed for Huadian Co., Taicheng Light, and Tianfu Communication, with growth rates of 502.17%, 642.80%, and 347.47% respectively [3][2] Group 3: Longcheng Pharmaceutical Industry Selection - Longcheng Pharmaceutical Industry Selection has also performed well, achieving a return of 102.02% in the first three quarters, qualifying it as a "doubling fund" [7][9] - The fund's scale increased from 1.132 billion to 1.790 billion yuan in the third quarter, marking a growth of nearly 60% [9] - The fund's top three holdings include Innovent Biologics, 3SBio, and Hotgen Biotech, with each holding a market value exceeding 100 million yuan [8][7] Group 4: Investment Focus and Strategy - The investment strategy of Yongying Technology Smart Selection emphasizes the cloud computing industry, with a focus on optical communication and PCB sectors, anticipating significant technological advancements by 2027 [6][2] - Longcheng Pharmaceutical Industry Selection is shifting its focus towards clinical data, overseas licensing, and domestic sales, indicating a strategic pivot towards non-oncology sectors [9][7]

证券代码：688068 证券简称：热景生物 公告编号：2025-065 在本研究的给药剂量和频率下，SGC001 注射液在前壁 ST 段抬高型心肌梗 死患者人群中安全耐受性良好，Ib 期临床研究中低（300mg）中（600mg）高（900mg） 剂量组均未发生 3 级及 3 级以上不良事件，未发生严重不良事件；且药物安全性 与剂量有明显相关性。 药代动力学分析显示，患者单次静脉输注 300~900 mg SGC001 注射液后， SGC001 的中位 Tmax 为 1.30~4.07 h，暴露（Cmax 和 AUC）随剂量增加而大致 北京热景生物技术股份有限公司 关于参股公司 SGC001 创新药 Ib 期临床研究获得 积极初步结果的自愿披露公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 近日，北京热景生物技术股份有限公司（以下简称"公司"或"热景生物"） 收到参股公司北京舜景生物医药技术有限公司（以下简称"舜景医药"）关于自 主研制的创新药 SGC001 注射液 Ib 期临床研究获得了积极的初步结果的汇报。 具体情 ...