1、公司不存在《管理办法》等法律、法规规定的禁止实施限制性股票激励 计划的情形，包括：（1）最近一个会计年度财务会计报告被注册会计师出具否 定意见或者无法表示意见的审计报告；（2）最近一个会计年度财务报告内部控 制被注册会计师出具否定意见或无法表示意见的审计报告；（3）上市后最近 36 个月内出现过未按法律法规、公司章程、公开承诺进行利润分配的情形；（4） 法律法规规定不得实行股权激励的；（5）中国证监会认定的其他情形。公司具 备实施限制性股票激励计划的主体资格。 2、公司 2025 年 A 股限制性股票激励计划所确定的激励对象不存在下列情 形：（1）最近 12 个月内被证券交易所认定为不适当人选；（2）最近 12 个月内 被中国证监会及其派出机构认定为不适当人选；（3）最近 12 个月内因重大违法 违规行为被中国证监会及其派出机构行政处罚或者采取市场禁入措施；（4）具 有《公司法》规定的不得担任公司董事、高级管理人员情形的；（5）法律法规 规定不得参与上市公司股权激励的；（6）中国证监会认定的其他情形。 的核查意见 康希诺生物股份公司（以下简称"公司"）监事会依据《中华人民共和国公司 法》（以下简称"《公司 ...

证券代码：688185 证券简称：康希诺 公告编号：2025-024 康希诺生物股份公司 第三届监事会第九次会议决议公告 本公司监事会及全体监事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、监事会会议召开情况 康希诺生物股份公司（以下简称"公司"）第三届监事会第九次会议于 2025 年 9 月 26 日在公司会议室以现场及通讯的方式召开。会议通知已于会议召开 5 日 前以电子邮件形式送达全体监事。本次会议由监事会主席肖治召集，应到监事 3 人，实到监事 3 人。会议的召集、召开和表决程序符合《中华人民共和国公司法》 等法律法规及规范性文件和《康希诺生物股份公司章程》（以下简称"《公司章 程》"）的规定，合法有效。 二、监事会会议审议情况 经与会监事审议，逐项表决，形成决议如下： （一）《关于公司<2025 年 A 股限制性股票激励计划（草案）>及其摘要的 议案》 监事会认为：公司《2025 年 A 股限制性股票激励计划（草案）》及其摘要的 内容符合《中华人民共和国公司法》《中华人民共和国证券法》《上市公司股权 激励管理办法》《上海证券交易 ...

证券代码：688185 证券简称：康希诺 公告编号：2025-023 康希诺生物股份公司 第三届董事会第二次临时会议决议公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 一、董事会会议召开情况 康希诺生物股份公司（以下简称"公司"）第三届董事会第二次临时会议于 2025 年 9 月 26 日在公司会议室以现场及通讯的方式召开。会议通知已于会议召 开 5 日前以电子邮件形式送达全体董事。本次会议由董事长 XUEFENG YU（宇学 峰）博士主持，应到董事 7 人，实到董事 7 人。会议的召集、召开和表决程序符 合《中华人民共和国公司法》（以下简称"《公司法》"）等法律法规及规范性 文件和《康希诺生物股份公司章程》（以下简称"《公司章程》"）的规定，合 法有效。 二、董事会会议审议情况 经与会董事审议，逐项表决，形成决议如下： （一）《关于公司<2025 年 A 股限制性股票激励计划（草案）>及其摘要的 议案》 为了进一步建立、健全公司长效激励机制，吸引和留住优秀人才，充分调动 公司员工的积极性，有效地将股东利益、公司利益 ...

截至发稿，康希诺市值为189亿元。 每经AI快讯，康希诺（SH 688185，收盘价：76.4元）9月26日晚间发布公告称，公司第三届第二次董事 会临时会议于2025年9月26日在公司会议室以现场及通讯的方式召开。会议审议了《关于公司<2025年A 股限制性股票激励计划（草案）>及其摘要的议案》等文件。 2024年1至12月份，康希诺的营业收入构成为：生物医药占比97.47%，其他业务占比2.53%。 每经头条（nbdtoutiao）——5年增长33倍，这类新险种卖爆了，身边很多人都需要，30多家险企蜂拥而 入⋯⋯ （记者 王晓波） ...

Market Overview - The biopharmaceutical sector experienced a decline of 0.21% on September 25, with Nossland leading the drop [1] - The Shanghai Composite Index closed at 3853.3, down 0.01%, while the Shenzhen Component Index closed at 13445.9, up 0.67% [1] Stock Performance - Notable gainers in the biopharmaceutical sector included: - Aopu Mai (688293) with a closing price of 62.85, up 7.42% and a trading volume of 30,600 [1] - Rongchang Biotech (688331) closed at 108.50, up 3.43% with a trading volume of 89,200 [1] - Baipusais (301080) closed at 62.16, up 3.43% with a trading volume of 43,500 [1] - Major decliners included: - Nossland (430047) closed at 22.99, down 3.69% with a trading volume of 57,000 [2] - Wufan Biotech (301393) closed at 53.12, down 3.42% with a trading volume of 24,600 [2] - Kexing Pharmaceutical (688136) closed at 38.75, down 3.34% with a trading volume of 53,500 [2] Capital Flow - The biopharmaceutical sector saw a net outflow of 207 million yuan from institutional investors, while retail investors contributed a net inflow of 45.07 million yuan [2] - Notable capital flows included: - Rongchang Biotech (688331) with a net inflow of 1.021 billion yuan from institutional investors [3] - Junshi Biosciences (688180) with a net inflow of 35.36 million yuan from institutional investors [3] - Aopu Mai (688293) with a net inflow of 9.41 million yuan from institutional investors [3]

Investment Rating - The investment rating for the pharmaceutical and biotechnology industry is "Positive" (maintained) [1] Core Insights - The industry is entering a new development phase driven by optimized procurement and innovation [3] - The raw material pharmaceutical sector is at a cyclical bottom, with companies actively transitioning to innovative drug development [5][8] - The vaccine sector is experiencing a decline in performance but is accelerating the layout of new technologies and products [6] - The medical services sector is leveraging AI technology to enhance efficiency and quality [7] Summary by Sections Raw Material Pharmaceutical Sector - The raw material pharmaceutical industry has faced a downturn for nearly four years, with prices of various products, such as sartans and heparins, reaching historical lows [5] - Revenue and net profit in the raw material pharmaceutical sector showed a downward trend in the first half of 2025 due to significant price drops in anti-infective products and increased R&D investments [5] - Companies like Huahai Pharmaceutical and Borui Pharmaceutical are focusing on innovative drug development, with several products in various clinical trial phases [5][68] Vaccine and Blood Products Sector - The vaccine industry is facing continuous performance decline due to a decrease in newborn numbers and changing competitive dynamics, although some companies are introducing new technologies and products [6] - The blood products sector is also experiencing a downturn, with revenue and net profit declining due to high inventory levels and suppressed demand from medical insurance [6][75] - The industry is expected to see increased consolidation as leading companies accelerate mergers and acquisitions [6][8] Medical Services Sector - The medical services sector's performance has declined due to DRGs and the consumption environment, but the application of AI technology is expected to enhance service quality and efficiency [7] - The core competitiveness of the medical services industry lies in acquiring and training quality doctors and hospital management [7] Investment Recommendations - The report suggests that companies in the raw material pharmaceutical sector are likely to enter a harvest period as they transition to innovative drugs [8] - The blood products sector is anticipated to accelerate consolidation, with significant mergers expected in the near future [8] - Recommended stocks include Federal Pharmaceutical, Pro Pharmaceutical, Guobang Pharmaceutical, and others, while benefiting stocks include Tianyu Co., Meinuo Pharma, and others [8]

中国经济网北京9月19日讯 康希诺(688185.SH)今日收报79.84元，跌幅2.63%。 康希诺募集资金总额为52.01亿元，扣除发行费用后，募集资金净额为49.79亿元。康希诺最终募集 资金净额较原计划多39.79亿元。康希诺2020年8月6日发布的招股说明书显示，公司计划募集资金10亿 元，分别用于"生产基地二期建设""在研疫苗开发""疫苗追溯、冷链物流体系及信息系统建设""补充流 动资金"。 康希诺上市发行费用为2.21亿元，其中保荐及承销费用2.05亿元。 中信证券投资有限公司（参与跟投的保荐机构相关公司）获配股票数量为49.60万股，占本次发行 总股数的2.00%，跟投金额为1.04亿元。 康希诺于2020年8月13日在上交所科创板上市，发行数量为2480万股，发行价格209.71元/股，保荐 机构（主承销商）为中信证券，保荐代表人为焦延延、马可；联席主承销商为中金公司，副主承销商为 渤海证券。目前该股处于破发状态。 （责任编辑：关婧） ...

中期報告 2025 2025 中期報告 | 目錄 | | --- | | 公司資料 | 02 | | --- | --- | | 財務概要 | 04 | | 管理層討論及分析 | 05 | | 其他資料 | 24 | | 獨立核數師報告 | 32 | | 簡明合併損益及其他綜合收益表 | 33 | | 簡明合併財務狀況表 | 34 | | 簡明合併權益變動表 | 36 | | 簡明合併現金流量表 | 37 | | 簡明合併財務報表附註 | 38 | | 釋義 | 63 | 02 康希諾生物股份公司 公司資料 董事會 執行董事 Xuefeng YU博 士 （董事長、首席執行官兼總經理） Shou Bai CHAO博 士 （首席運營官兼副總經理） 王靖女士 （首席商務官兼副總經理） 非執行董事 李志成先生 獨立非執行董事 桂水發先生 劉建忠先生 張耀樑先生 審計委員會 張耀樑先生 （主任委員） 桂水發先生 劉建忠先生 薪酬與考核委員會 桂水發先生 （主任委員） 張耀樑先生 Xuefeng YU博 士 提名委員會 劉建忠先生 （主任委員） 張耀樑先生 桂水發先生 李志成先生 Xuefeng YU 博 士 監 事 肖 ...

Core Viewpoint - 康希诺's stock price has shown volatility with a year-to-date increase of 33.84%, but recent trading indicates a slight decline in the short term [1][2]. Financial Performance - As of June 30, 康希诺 reported a revenue of 3.82 billion yuan for the first half of 2025, reflecting a year-on-year growth of 26.00% [2]. - The company experienced a net profit loss of 1348.54 million yuan, which is an improvement of 94.02% compared to the previous period [2]. Stock Market Activity - On September 17, 康希诺's stock price decreased by 2.07%, trading at 81.71 yuan per share with a total market capitalization of 202.19 billion yuan [1]. - The stock saw a net outflow of 616.01 million yuan in principal funds, with significant selling pressure from large orders [1]. Shareholder Information - As of June 30, 康希诺 had 17,500 shareholders, a decrease of 1.92% from the previous period [2]. - The average number of circulating shares per shareholder remained at 0 [2]. Dividend Information - 康希诺 has distributed a total of 1.98 billion yuan in dividends since its A-share listing, with no dividends paid in the last three years [3].

Core Viewpoint - The vaccine industry is experiencing a downturn, with significant revenue and profit declines among major companies, attributed to price wars, vaccine hesitancy, and intense competition [4][5][10][20]. Group 1: Industry Performance - In the first half of 2025, the overall vaccine revenue of listed companies in China decreased by 60% year-on-year, and net profit dropped by 113% [5]. - Major vaccine companies like Zhifei Biological and Wantai Biological reported their first half-year losses since going public, with net profits declining by 127% and 155% respectively [5][10]. - Only six out of 17 listed vaccine companies achieved profitability, with the highest profit being 122 million yuan from Chengda Biological [5]. Group 2: Price Wars - The price of flu vaccines has significantly dropped, with some prices reaching as low as 5.5 yuan per dose, leading to a continuous price war in the market [8][9]. - Wantai Biological's revenue from its main product, the bivalent HPV vaccine, fell by 38% to 844 million yuan, marking its first loss since listing [10]. - The price competition has also affected other vaccines, including HPV and shingles vaccines, with prices dropping dramatically in recent years [9][10][11]. Group 3: Vaccine Hesitancy - Vaccine hesitancy has become a significant issue, particularly for non-mandatory vaccines like HPV and flu vaccines, with many individuals expressing doubts about their effectiveness [13][14][15]. - The average flu vaccine coverage in China remains below 4%, significantly lower than in developed countries where it is around 50% [15]. - Factors contributing to vaccine hesitancy include dissatisfaction with COVID-19 vaccine outcomes, misinformation, and a lack of awareness regarding adult vaccinations [15][16]. Group 4: Future Outlook - Experts predict that the current downturn in the vaccine industry may last for five to ten years, with potential consolidation and elimination of weaker companies [20]. - The industry faces challenges in changing public perception and increasing adult vaccination rates, which are crucial for market expansion [20]. - The competition is expected to remain fierce, with many companies struggling to differentiate their products in a saturated market [19][20].