Financial Performance - In 2024, the company's revenue increased by 4.77% year-on-year, while the net profit attributable to shareholders decreased by 2.29%, marking the first instance of negative growth [2] - The gross margin for the API segment declined by 2.59 percentage points to 14.79%, and CDMO revenue fell by 6.05% year-on-year [2] - The formulation business showed minimal growth of only 0.51% [2] Challenges and Responses - Profit growth slowdown is attributed to market conditions, industry policies, and increased fixed asset depreciation and R&D investment [3] - The company is focusing on enhancing the integration of API and formulation businesses to improve competitiveness and sustainability [3] - The company is actively addressing risks from policy changes and market fluctuations, including price volatility in traditional products like antibiotics and veterinary drugs [4] R&D and Talent Management - R&D expenses increased by 2.66% year-on-year, but the number of R&D personnel decreased by 4.07%, indicating a challenge in converting technical investment into human resource optimization [3] - The company plans to maintain a moderate increase in R&D personnel in 2025 to support business development [3] Strategic Initiatives - The company has optimized its development strategy for 2024, focusing on strengthening its core areas: refining APIs, enhancing CDMO capabilities, and expanding into medical aesthetics [8] - Plans to accelerate the development of new formulation products, with an expectation to initiate 25 new projects annually [9] Market Expansion and Internationalization - The company is advancing its internationalization strategy, establishing BD offices in the US, Europe, and Japan to enhance overseas market penetration [10] - The impact of the US Biodefense Act on the company's operations is expected to be minimal [13] Product Development and Future Outlook - The company’s clinical trial for the semaglutide project is progressing well, currently in the Phase III enrollment stage [5] - The company anticipates that the veterinary drug market will perform better than the previous year and will adjust production plans accordingly [5] - New production lines for solid formulations and APIs are expected to be operational in 2025 [13]

Investment Rating - The report maintains a "Strong Buy" investment rating for the company [4][8]. Core Insights - The company reported a revenue of 12.022 billion yuan in 2024, representing a year-on-year growth of 4.77%, while the net profit attributable to shareholders decreased by 2.29% to 1.031 billion yuan [1][3]. - The CDMO (Contract Development and Manufacturing Organization) segment continues to show robust growth, with a significant increase in project numbers, indicating a strong future growth potential [2][4]. - The report highlights that the company's short-term performance is under pressure due to changes in the business environment, particularly in the raw material and formulation sectors, but the long-term competitive strength remains intact [1][4]. Financial Performance Summary - In 2024, the company achieved a total revenue of 12.022 billion yuan, with a year-on-year growth of 4.77% [1]. - The net profit attributable to shareholders for 2024 was 1.031 billion yuan, down 2.29% from the previous year [1]. - The CDMO segment generated revenue of 1.884 billion yuan, a decrease of 6.05% year-on-year, but the number of ongoing projects increased significantly [2]. - The raw material segment reported revenue of 8.651 billion yuan, with an 8.32% year-on-year growth, while the formulation segment achieved revenue of 1.256 billion yuan, growing by 0.51% [4][8]. Project and Market Dynamics - The company has a total of 1,601 quoted projects, a 77% increase year-on-year, with 996 ongoing projects, up 35% [2]. - The number of commercialized projects reached 355, reflecting a 25% increase, while the R&D phase projects grew by 42% to 641 [2]. - The API (Active Pharmaceutical Ingredient) projects also saw a 40% increase, with 22 projects already in production [2]. Valuation Metrics - The report projects net profits for 2025, 2026, and 2027 to be 1.129 billion yuan, 1.290 billion yuan, and 1.530 billion yuan, respectively, with year-on-year growth rates of 10%, 14%, and 19% [3][8]. - The current PE ratio is 16.9, with projections of 15.8, 13.8, and 11.6 for the following years [10].

Investment Rating - The investment rating for the company is "Buy" (maintained) [5] Core Views - The company is expected to enter a trend of improving profitability due to the increasing revenue share from high-margin businesses such as CDMO and formulations, along with rising capacity utilization and production efficiency [1][10] - The financial performance shows short-term profit pressure but maintains high operational quality, with 2024 revenue reaching 12.022 billion yuan, a year-on-year increase of 4.77%, and a net profit of 1.031 billion yuan, a decline of 2.29% year-on-year [1][2] Summary by Relevant Sections Financial Performance - In 2024, the company achieved a revenue of 12.022 billion yuan, with a net profit of 1.031 billion yuan, reflecting a year-on-year decline of 2.29% [1] - The cash flow from operating activities was 1.209 billion yuan, showing a strong operational quality with a year-on-year increase of 17.20% [1] Growth Potential - The raw material and intermediate business saw stable growth, with sales revenue of 8.651 billion yuan in 2024, an increase of 8.32% year-on-year [2] - The CDMO business reported revenue of 1.884 billion yuan in 2024, despite a year-on-year decline of 6.05%, with a significant increase in project numbers, indicating strong growth potential [3] Profitability - The overall gross margin for 2024 was 23.85%, a decrease of 1.81 percentage points year-on-year, primarily due to the decline in gross margin from the raw material and intermediate business [4] - The company is expected to enter a period of improving profitability as high-margin business revenues increase and production efficiency improves [10] Earnings Forecast and Valuation - The earnings per share (EPS) for 2025-2027 are projected to be 1.00, 1.13, and 1.36 yuan respectively, with a price-to-earnings (P/E) ratio of 15 times for 2025 [11] - The company is anticipated to enter a new cycle of high-quality growth driven by supply upgrades as capacity is gradually released [11]

Investment Rating - The investment rating for the company is "Buy" (maintained) [5] Core Views - The company is expected to enter a trend of improving profitability due to the increasing revenue share from high-margin businesses such as CDMO and formulations, along with rising capacity utilization and production efficiency [1][10] - The financial performance shows short-term profit pressure but maintains high operational quality, with 2024 revenue at 12.022 billion yuan, a year-on-year increase of 4.77%, and a net profit of 1.031 billion yuan, down 2.29% year-on-year [1][2] Financial Performance Summary - In 2024, the company achieved revenue of 12.022 billion yuan, with a net profit of 1.031 billion yuan, reflecting a decline in profitability [1] - The cash flow from operating activities was 1.209 billion yuan, up 17.20% year-on-year, indicating strong operational quality [1] - The overall gross margin for 2024 was 23.85%, a decrease of 1.81 percentage points year-on-year, primarily due to a decline in the gross margin of the raw material and intermediate business [4] Growth Potential Summary - The raw material and intermediate business saw stable growth, with sales revenue of 8.651 billion yuan in 2024, an increase of 8.32% year-on-year [2] - The CDMO business maintained strong growth, with 1,601 quoted projects, a 77% increase year-on-year, and 996 ongoing projects, a 35% increase year-on-year [3] - The pharmaceutical business generated revenue of 1.256 billion yuan in 2024, with a focus on a multi-variety development strategy and a pipeline of 64 projects [4] Profitability Outlook - The company is expected to enter a period of improving profitability as the revenue share from high-margin businesses increases [10] - The projected earnings per share (EPS) for 2025-2027 are 1.00, 1.13, and 1.36 yuan, respectively, indicating a positive growth trajectory [11]

Investment Rating - The report maintains a "Buy" rating for the company, indicating an expected relative performance increase of over 15% against the benchmark index within the next 6 to 12 months [2][33]. Core Insights - The company reported a revenue of 12.022 billion yuan for 2024, reflecting a year-on-year growth of 4.77%. However, the net profit attributable to shareholders decreased to 1.031 billion yuan, down 2.29% year-on-year [2][5]. - The CDMO (Contract Development and Manufacturing Organization) segment is expected to be a significant growth driver, with revenue projected at 1.884 billion yuan for 2024, despite a decline of 6.05% [3][4]. - The API (Active Pharmaceutical Ingredients) segment is anticipated to generate 8.651 billion yuan in revenue for 2024, showing an increase of 8.32% [4]. - The formulation segment is expected to achieve revenue of 1.256 billion yuan in 2024, with a slight growth of 0.51% [4]. Financial Performance Summary - The company achieved a total revenue of 11.474 billion yuan in 2023, with a year-on-year growth rate of 8.81% [2]. - The projected revenues for 2025, 2026, and 2027 are 12.815 billion yuan, 14.218 billion yuan, and 15.941 billion yuan, respectively, with growth rates of 6.59%, 10.95%, and 12.12% [2][5]. - The net profit attributable to shareholders is forecasted to be 1.119 billion yuan in 2025, reflecting an 8.55% year-on-year growth [2][5]. Business Segment Analysis - The CDMO segment has shown a rapid increase in project numbers, with 1,601 quoted projects (+77%) and 996 ongoing projects (+35%) [3]. - The API segment is expanding its production capacity with the completion of new high-end production facilities and plans for additional projects [4][12]. - The formulation segment is also set to enhance its production capabilities with new facilities under design, aiming to improve overall production efficiency [4][12].

Investment Rating - The report maintains a "Buy" rating for Prolo Pharmaceutical (000739) [1] Core Views - Prolo Pharmaceutical is accelerating its integrated layout of raw materials and formulations, with CDMO expected to enter a new inflation era [1] - The company has established a 2030 development strategy focusing on refining raw materials, strengthening CDMO, enhancing pharmaceuticals, and expanding into medical aesthetics [4][19] - The company has demonstrated long-term development confidence through stock buybacks, with a total repurchase amount of 1.53 billion yuan planned for cancellation [4][23] Summary by Sections Company Overview - Prolo Pharmaceutical, founded in 1989 and listed in 2001, is a leading pharmaceutical manufacturer in China, focusing on raw materials, CDMO, pharmaceuticals, and medical aesthetics [18] - The company has undergone significant strategic adjustments since 2017, implementing a unified management model and achieving its strategic goals by 2023 [19] Raw Material and Medical Aesthetics Business - The company is a leading domestic player in specialty raw materials, with a focus on oral cephalosporins, penicillins, and veterinary raw materials [5] - Prolo has increased the number of API projects significantly, with plans to add 30-50 new DMFs in the next 3-5 years [5] CDMO Business Outlook - The CDMO sector is expected to enter a new inflation era, driven by supportive policies for innovative drugs and a significant increase in project numbers [6][8] - The company has seen a 42% year-on-year increase in projects, indicating a robust growth trajectory for its CDMO business [8] Revenue Growth and Business Segmentation - Prolo's revenue has grown from 78.80 billion yuan in 2020 to an estimated 120.22 billion yuan in 2024, with a compound annual growth rate (CAGR) of 11.14% [32] - The revenue contribution from CDMO and formulation businesses has increased, with CDMO revenue growing at a CAGR of 15.60% from 2020 to 2024 [34] Profitability and Financial Metrics - The company's gross margin has decreased from 27.96% in 2020 to 23.85% in 2024, while the net margin has also declined [38] - Despite the decline in margins, the company continues to invest in R&D, with R&D expenses increasing from 4.44% to 5.34% of total revenue [38]

普洛药业(000739) 昨收盘:15.28 医药生物 原料药制剂一体化布局加速，CDMO 有望迎来新通胀时代 走势比较 (20%) (8%) 4% 16% 28% 40% 24/3/18 24/5/29 24/8/9 24/10/20 24/12/31 25/3/13 股票数据 2025 年 03 月 17 日 公司深度研究 买入/维持 | 总股本/流通(亿股) | 11.69/11.69 | | --- | --- | | 总市值/流通(亿元) | 178.67/178.61 | | 12 个月内最高/最低价 | 18.96/12.23 | | (元) | | 相关研究报告 <<普洛药业（000739）2021 年一季报 点评：Q1 业绩超预期，产能建设进入 提速期>>--2021-04-20 <<普洛药业（000739）2020 年年报点 评：全年业绩略预期，CDMO 业务进入 加速期>>--2021-03-12 <<普洛药业（000739）2020 年三季报 点评：Q3 业绩符合预期，公司业务结 构改善明显>>--2020-10-22 证券分析师：周豫 E-MAIL：zhouyua@tpyzq.com ...

Investment Rating - The report maintains a "Buy" rating for Prolo Pharmaceutical (000739) [1] Core Views - Prolo Pharmaceutical is accelerating its integrated layout of raw materials and formulations, with CDMO expected to enter a new inflation era [1] - The company has established a 2030 development strategy focusing on refining raw materials, strengthening CDMO, enhancing pharmaceuticals, and expanding into medical beauty [4][19] - The company has demonstrated long-term development confidence through stock buybacks, with a total repurchase amount of 1.53 billion yuan planned for cancellation [4][23] Summary by Sections Company Overview - Prolo Pharmaceutical, founded in 1989 and listed in 2001, is a leading pharmaceutical manufacturer in China, focusing on raw materials, CDMO, pharmaceuticals, and medical beauty products [18] - The company has seven raw material production plants and two formulation plants, with a complete industrial chain from intermediates to sales channels [18][19] Raw Material and Medical Beauty Business - The company is a leading domestic player in specialty raw materials, with significant market positions in oral cephalosporins and other key products [5] - Prolo has increased the number of API projects significantly, with plans to add 30-50 new DMFs in the next 3-5 years [5] - The medical beauty division is expanding, focusing on cosmetic raw materials and collagen products, with future plans for botulinum toxin [5] CDMO Business Outlook - The CDMO sector is expected to enter a new inflation era, driven by supportive policies for innovative drugs and a significant increase in project numbers [6][8] - The company has seen a 42% year-on-year increase in projects, indicating a strong growth trajectory for its CDMO business [8] Revenue Growth and Business Segmentation - Prolo's revenue has grown from 78.80 billion yuan in 2020 to an estimated 120.22 billion yuan in 2024, with a compound annual growth rate (CAGR) of 11.14% [32] - The revenue contribution from CDMO and formulation businesses is increasing, with CDMO revenue growing at a CAGR of 15.60% from 2020 to 2024 [34] Financial Projections - The company forecasts revenues of 130.58 billion yuan, 143.93 billion yuan, and 159.58 billion yuan for 2025, 2026, and 2027, respectively, with corresponding net profits of 11.53 billion yuan, 13.24 billion yuan, and 15.48 billion yuan [10][12]

证券研究报告·A 股公司简评 化学制药 原料药业务韧性凸显， 看好制剂及 CDMO 加速 核心观点 公司 2024 年收入端在核心板块带动下保持平稳，利润端预计受 到 API 品种价格和制剂行业趋势等因素略有扰动。原料药业务韧 性凸显，产能释放有望带来增量。CDMO 能力升级，项目增长趋 势良好。制剂品种扩充，盈利能力提升。研发投入保持高强度， 搭建完善技术平台。展望 2025，我们认为值得关注：1）原料药 板块医美、合成生物学等新兴业务贡献业绩增量；2）CDMO：D 端 M 端齐发力；3）制剂管线扩充拉动增速；4）兽药品种价格见 底回升，需求端兽药使用量预计有望边际向上，关注兽药弹性。 事件 公司发布 2024 年年度报告及分红预案 公司 2024 年实现营业总收入 120.22 亿元，同比增长 4.77% ； 归母净利润 10.31 亿元，同比下降 2.29%；扣非归母净利润 9. 84 亿元，同比下降 4.09%。 分红预案：拟每 10 股派发现金红利 3.56 元（含税），合计 派发现金红利 4.12 亿元，现金分红比例 40%。2024 年度公司回 购股份注销总金额 2 亿元，现金分红和回购注销金额 ...

证券代码：000739 证券简称：普洛药业 公告编号：2025-19 普洛药业股份有限公司 关于举行 2024 年年度报告网上业绩说明会的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 重要内容提示： 普洛药业股份有限公司（以下简称"公司"）已于 2025 年 3 月 11 日在《证 券时报》和巨潮资讯网（www.cninfo.com.cn）披露公司 2024 年年度报告。为进 一步加强与投资者的深入交流，使投资者更加全面、深入地了解公司情况，公司 将于 2025 年 3 月 27 日（星期四）下午 15：00-16：00 通过易董价值在线平台 （www.ir-online.cn）举行 2024 年度业绩说明会。 一、说明会类型 本次业绩说明会以网络方式召开，公司将针对 2024 年度业绩和经营情况相 关事宜与投资者进行互动交流，在信息披露允许的范围内就投资者普遍关注的问 题进行回答。 （3）投资者可于 2025 年 3 月 27 日 13:00 前通过小程序进行会前提问，公 司将通过本次业绩说明会，在信息披露允许范围内就投资者普遍关注的问题进行 回答。 ...