证券代码：002603 证券简称：以岭药业 公告编号：2025-050 石家庄以岭药业股份有限公司 关于召开 2025 年第二次临时股东大会的通知 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假记载、误导性陈述 或重大遗漏。 一、召开会议的基本情况 1、股东会届次：2025 年第二次临时股东大会 2、股东会的召集人：董事会 3、本次会议的召集、召开符合《中华人民共和国公司法》《深圳证券交易所股票 上市规则》《深圳证券交易所上市公司自律监管指引第 1 号——主板上市公司规范运 作》等法律、行政法规、部门规章、规范性文件及《公司章程》的有关规定。 4、会议时间： （1）现场会议时间：2025 年 12 月 22 日 14:50 （2）网络投票时间：通过深圳证券交易所系统进行网络投票的具体时间为 2025 年 12 月 22 日 9:15-9:25，9:30-11:30，13:00-15:00；通过深圳证券交易所互联网投 票系统投票的具体时间为 2025 年 12 月 22 日 9:15 至 15:00 的任意时间。 5、会议的召开方式：现场表决与网络投票相结合。 6、会议的股权登记日：2025 ...

石家庄以岭药业股份有限公司 第八届监事会第十四次会议决议公告 石家庄以岭药业股份有限公司第八届监事会第十四次会议于 2025 年 12 月 5 日在公司会议室以现场方式召开。本次会议通知和文件于 2025 年 11 月 26 日以 电话通知并电子邮件方式发出。会议应出席监事 3 人，实际出席监事 3 人。会议 由公司监事会主席高学东主持。本次会议的召集程序、审议程序和表决方式均符 合《公司法》、相关法律法规及本公司章程的规定。 证券代码：002603 证券简称：以岭药业 公告编号：2025-046 特此公告。 石家庄以岭药业股份有限公司 监事会 2025 年 12 月 6 日 会议以记名投票表决方式审议通过了《关于募集资金投资项目结项并将节余 募集资金永久补充流动资金的议案》。 监事会认为：募集资金投资项目结项并将节余募集资金永久补充流动资金， 是基于公司整体发展做出的审慎决定，符合公司实际经营需要，有利于支持公司 日常经营及业务发展，提高募集资金的安全性和使用效率，降低公司资金成本， 符合全体股东利益。本次结项募投项目及节余募集资金使用的审议程序符合有关 法律法规、《公司章程》等规定，审议程序和表决结果合法 ...

证券代码：002603 证券简称：以岭药业 公告编号：2025-045 石家庄以岭药业股份有限公司 第八届董事会第十九次会议决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚 假记载、误导性陈述或重大遗漏。 石家庄以岭药业股份有限公司（以下简称"公司"）第八届董事会第十九次 会议于 2025 年 12 月 5 日在公司会议室以现场方式召开。本次会议通知和文件于 2025 年 11 月 26 日以电话通知并电子邮件方式发出。会议应出席董事 9 人，实 际出席董事 9 人。会议由公司董事长吴相君主持，监事会成员、公司高级管理人 员列席了会议。本次会议的召集程序、审议程序和表决方式均符合《公司法》、 相关法律法规及本公司章程的规定。 会议以记名投票表决方式审议通过了以下议案并形成决议如下： 一、审议通过了《关于修改<公司章程>的议案》。 根据《中华人民共和国公司法》《深圳证券交易所股票上市规则》及《上市 公司章程指引》《上市公司股东会规则》等相关法律法规、规范性文件的最新规 定，并结合公司实际情况，公司决定对现有的《公司章程》予以修订。 表决情况：同意 9 票，反对 0 票，弃权 0 票。 ...

南财智讯12月5日电，以岭药业公告，公司于2025年12月5日召开第八届董事会第十九次会议、第八届监 事会第十四次会议，审议通过了《关于募集资金投资项目结项并将节余募集资金永久补充流动资金的议 案》，同意对"化学制剂国际产业化项目"予以结项，该项目已建设完毕并达到预定可使用状态。截至 2025年11月30日，该项目节余募集资金金额为16101.99万元（未包含银行存款利息收入扣除银行手续费 等的净额及理财收益，最终金额以资金转出当日募集资金专用账户实际余额为准）。公司拟将上述节余 资金永久补充流动资金，用于日常生产经营。董事会授权财务中心在实施完毕后办理相应募集资金专户 的销户手续，相关监管协议随之终止。该事项尚需提交公司股东大会审议。 ...

Core Viewpoint - Hebei Yiling Pharmaceutical has been recognized as an advanced intelligent factory in Hebei Province, highlighting its successful digital transformation in traditional Chinese medicine production [1][4]. Company Overview - Hebei Yiling Pharmaceutical, a wholly-owned subsidiary of Shijiazhuang Yiling Pharmaceutical, has established a modern high-tech production base for traditional Chinese medicine extraction, formulations, and health products [3]. - The company aims to create a modern, digital, and intelligent shared supply chain ecosystem [3]. Intelligent Factory Project - The intelligent factory project is a key initiative for Yiling Pharmaceutical's strategy in modernizing traditional Chinese medicine production [3]. - The project integrates automated production lines, artificial intelligence, and big data analysis to enhance precision control and traceability in core processes [4]. Digital Transformation and Innovation - The company is advancing full-chain digital integration, utilizing AI and industrial internet technologies to build a smart operation system covering energy management, production execution, and quality control [4]. - A notable innovation is the "shared manufacturing" platform model, which offers flexible processing and R&D services to small and medium-sized enterprises in the industry [4]. Environmental Sustainability - Yiling Pharmaceutical is responding to green manufacturing initiatives by implementing energy-saving projects such as biogas utilization, photovoltaic power generation, and condensate water recovery [4]. - This approach optimizes energy use and creates a new model where "intelligent manufacturing" and "green energy saving" mutually empower each other, enhancing production efficiency, management effectiveness, and environmental benefits [4]. Industry Context - The recognition of advanced intelligent factories aims to set benchmarks for smart manufacturing and guide industrial upgrades in Hebei Province [4]. - A total of 217 units were recognized in this evaluation, emphasizing the importance of intelligent factories in optimizing production processes and supporting high-quality development in the real economy [4].

Core Viewpoint - The Chinese traditional medicine sector is experiencing increased activity due to a surge in flu cases, with the Chinese Medicine ETF (560080) showing a slight decline but still attracting investor interest [1][9]. Market Performance - The Chinese Medicine ETF (560080) closed down 0.91% today, remaining in a consolidation phase, with a trading volume exceeding 84 million yuan, a 7% increase from the previous trading day [1]. - The ETF's closing premium rate was 0.06%, indicating ongoing investor attention, with two out of the last five days seeing inflows [1]. - The ETF's latest scale reached 2.598 billion yuan, leading its peers in the same category [1]. Stock Performance - Most constituent stocks of the Chinese Medicine ETF closed in the red, with notable declines including: - Pianzaihuang down 1.59% to 168.75 yuan, marking a five-year low [3]. - Yiling Pharmaceutical down over 3%, and Zhongsheng Pharmaceutical down over 2% [3]. - Conversely, stocks like Yunnan Baiyao and Jilin Aodong saw slight increases [3]. Valuation Metrics - As of December 3, the TTM price-to-earnings (PE) ratio for the ETF's index was 25.12, positioned at the 23.11% percentile over the past decade, suggesting that the index is cheaper than 76% of the time historically [5]. - The TTM PE is just 0.38 away from the calculated opportunity value, indicating a potential entry point for investors [5]. Historical Performance - The year-to-date return for the Chinese Medicine Index remains negative at -2.24%, with a decline of 8.13% projected for 2024 [7]. - The index has shown a pattern of consecutive declines, with four consecutive negative years if 2023 is considered a down year [7]. Demand Drivers - The recent flu outbreak has led to a significant increase in demand for respiratory medications, with flu cases reported rising by 53.8% compared to the previous week [9]. - The flu activity is at its highest level since 2022, which is expected to boost the demand for related medications [9]. Industry Outlook - Analysts from Zheshang Securities predict an inflection point for the Chinese medicine sector, suggesting that the sector will attract more investment due to its stable cash flow and lower volatility compared to other sectors [9]. - The industry is expected to see improved revenue and net profit growth in the second half of 2025, aided by reduced cost pressures from declining raw material prices [9].

Core Viewpoint - Yiling Pharmaceutical has launched its self-developed innovative traditional Chinese medicine, Qifang Nasal Tablets, for the treatment of persistent allergic rhinitis, providing a new treatment option for millions of patients in China [1][6]. Group 1: Product Information - Qifang Nasal Tablets are classified as a national Class 1.1 innovative traditional Chinese medicine and have received national invention patents and support from provincial and ministerial key research projects [3]. - The product is based on the clinical experience of Professor Li Shuliang from the Chinese Academy of Medical Sciences and incorporates elements from classic formulas "Yupingfeng San" and "Xinyi San" [6]. - Clinical trials showed a total effective rate of 89% after four weeks of treatment, with significant improvements in nasal and eye symptoms compared to the control group [6]. Group 2: Market Context - Allergic rhinitis is a common chronic disease in China, with a self-reported prevalence rate of 17.6%, indicating that approximately 1 in 6 people suffers from this condition [1]. - The demand for safe, effective, and long-term treatment options is urgent among patients suffering from allergic rhinitis [1]. Group 3: Collaboration and Distribution - Yiling Pharmaceutical has partnered with Alibaba Health to leverage its digital service capabilities for the comprehensive market launch of Qifang Nasal Tablets [6][7]. - Alibaba Health aims to enhance disease knowledge dissemination and improve drug accessibility through its nationwide distribution network [7].

Group 1 - The core viewpoint of the news highlights the active performance of the traditional Chinese medicine (TCM) sector, particularly in the context of the flu season, with the TCM ETF (560080) rising nearly 1% and experiencing a significant increase in trading volume [1][3] - Recent data from the CDC indicates that the positive rate of flu virus tests in emergency departments nationwide has approached 45%, with some regions experiencing high levels of flu activity, leading to a surge in sales of cold-related medications [3][10] - The TCM ETF (560080) has seen a net inflow of over 24 million yuan as of November 28, with its latest scale reaching 2.581 billion yuan, leading its peers in the same category [1][3] Group 2 - The performance of individual stocks within the TCM ETF has been notable, with several flu-related stocks experiencing significant gains, such as Guangdong Wannianqing hitting the daily limit and Tai Long Pharmaceutical rising over 6% [3][4] - The TCM ETF's index has a TTM price-to-earnings ratio of 24.86, indicating it is cheaper than 79% of the time over the past decade, suggesting a favorable valuation for potential investment [5] - The TCM index has shown negative returns year-to-date, with a decline of 2.24% in 2023, and a historical trend of alternating between gains and losses over the past several years [7][8] Group 3 - The TCM industry is expected to see a short-term easing of pressure due to inventory clearance, with a positive outlook for demand recovery towards the end of the year [10] - Recent price governance initiatives across various regions aim to create a more unified and competitive market for TCM products, focusing on high-priced traditional Chinese medicines [10][11] - The ongoing price governance and centralized procurement processes are likely to reshape competition in the industry, favoring companies with strong clinical value, cost control, and market coverage capabilities [11]

Core Viewpoint - Yiling Pharmaceutical's innovative traditional Chinese medicine, Yangzheng Xiaojie Capsule, has been approved for sale in Thailand, marking a significant milestone in the company's internationalization strategy and highlighting the growing global recognition of traditional Chinese medicine in the oncology field [1][3]. Group 1: Product Approval and Significance - Yangzheng Xiaojie Capsule is the latest product from Yiling Pharmaceutical to receive registration in Thailand, following the success of Lianhua Qingwen Capsule, Shensong Yangxin Capsule, and Jinlidag Granules [1]. - The approval signifies the unique value of traditional Chinese medicine in cancer treatment is increasingly acknowledged internationally [1]. Group 2: Research and Efficacy - Joint research by Professor Jiang Wenguo from Cardiff University and Yiling Pharmaceutical found that Yangzheng Xiaojie Capsule significantly interferes with tumor cell invasion and metastasis by inhibiting the overactivation of the PI3K/Akt signaling pathway [2]. - Clinical studies led by Academician Yu Jinming showed that Yangzheng Xiaojie Capsule combined with chemotherapy significantly improved the quality of life for patients with advanced non-small cell lung cancer, with a clinical symptom improvement rate of 83.5% [2]. - Another study indicated that the combination of Yangzheng Xiaojie Capsule with interventional chemotherapy for primary liver cancer resulted in a total effective rate of 65.2%, significantly higher than the control group's 36.1% [2]. Group 3: Safety Profile - A meta-analysis involving 19 studies and 2,125 patients demonstrated that Yangzheng Xiaojie Capsule effectively alleviates gastrointestinal reactions caused by radiotherapy and chemotherapy, mitigates bone marrow suppression, and protects liver function, indicating good safety [3]. Group 4: Market Expansion - The approval of Yangzheng Xiaojie Capsule in Thailand is a vital step in Yiling Pharmaceutical's international strategy and serves as a practical example of traditional Chinese medicine contributing to the "Belt and Road" initiative [3]. - Yiling Pharmaceutical has successfully registered and launched 17 innovative traditional Chinese medicines in over 50 countries and regions worldwide [3].

Macro Strategy - In October, industrial enterprise profits showed a significant decline, with a year-on-year drop from 21.60% in September to -5.5% in October, leading to a cumulative year-on-year growth rate decrease from 3.20% to 1.90% [2] - The A-share market experienced a rebound from November 24 to November 28, with major indices such as the Shanghai Composite Index rising by 1.40% and the ChiNext Index increasing by 4.54% [3][4] - The rebound in A-shares was attributed to a reversal in the market's previous downward momentum, driven by a shift in expectations regarding the Federal Reserve's interest rate decisions and a recovery in the technology sector [3][4] Industry and Company Analysis Traditional Chinese Medicine Industry - The Traditional Chinese Medicine (TCM) sector saw a slight increase of 1.29% last week, the smallest among secondary sub-sectors in the pharmaceutical industry [9] - The price index for TCM materials showed a slight increase of 0.4%, indicating a recovery in market conditions and improved investor sentiment [12] - Multiple regions have initiated price governance for traditional Chinese medicine, aiming to create a unified and competitive market structure [13] Investment Recommendations - The report maintains an "overweight" rating for the TCM industry, suggesting three main investment themes: 1. Price governance, focusing on companies with strong R&D capabilities and unique products that can benefit from price reductions [15] 2. Consumption recovery, driven by macroeconomic improvement and increased health awareness among the aging population, favoring leading TCM brands [16] 3. State-owned enterprise reform, which is expected to enhance performance and create investment opportunities [16] - Recommended stocks include Zhaoli Pharmaceutical and Yiling Pharmaceutical, with a focus on companies with strong R&D capabilities and unique products [16]