证券代码：301333 证券简称：诺思格 公告编号：2026-006 诺思格（北京）医药科技股份有限公司 第五届董事会第十八次会议决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确、完 整，没有虚假记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 诺思格（北京）医药科技股份有限公司（以下简称"公司"）第五届董事会 第十八次会议（以下简称"本次会议"）于2026年3月17日在公司会议室以现场结 合通讯方式召开。会议通知已于2026年3月6日以电子邮件及专人送达等方式送达 全体董事。本次会议应出席董事11人，实际出席董事11人。会议由董事长WU JIE （武杰）先生主持，会议的召开符合有关法律、法规、规章和《诺思格（北京） 医药科技股份有限公司章程》（以下简称"《公司章程》"）的规定。 （一）审议通过《关于部分募投项目延期及内部投资结构调整的议案》 表决情况：11票同意；0票弃权；0票反对。 经审议，董事会认为：公司本次部分首次公开发行股票募集资金投资项目延 期（以下简称"募投项目"）及内部投资结构调整是基于公司实际经营情况做出 的审慎决定，未改变募投项目的实施主体、募集资金投资用途及投资规模，符合 ...

关于诺思格（北京）医药科技股份有限公司 部分募投项目延期及内部投资结构调整的核查意见 中国国际金融股份有限公司（以下简称"中金公司"或"保荐机构"）作为诺思格（北 京）医药科技股份有限公司（以下简称"诺思格"或"公司"）的保荐机构，根据《证券发 行上市保荐业务管理办法》《深圳证券交易所创业板股票上市规则》《上市公司募集资 金监管规则》《深圳证券交易所上市公司自律监管指引第 2 号——创业板上市公司规范 运作》《深圳证券交易所上市公司自律监管指引第 13 号——保荐业务》等有关法律、 行政法规、部门规章及业务规则的要求，对诺思格本次部分募投项目延期及内部投资结 构调整进行了认真、审慎核查，具体情况如下： 一、募集资金基本情况 经中国证券监督管理委员会《关于同意诺思格（北京）医药科技股份有限公司首次 公开发行股票注册的批复》（证监许可[2022]1185 号）同意注册，公司首次公开发行人 民币普通股（A 股）股票 1,500 万股，每股面值 1.00 元，每股发行价格为人民币 78.88 元，募集资金总额为人民币 1,183,200,000 元，扣除与发行有关的费用 95,601,797.73 元 （不含增值税） ...

中国国际金融股份有限公司 关于诺思格（北京）医药科技股份有限公司 2025 年度持续督导培训情况的报告 深圳证券交易所： 中国国际金融股份有限公司（以下简称"中金公司"或"保荐机构"）根据《深 圳证券交易所上市公司自律监管指引第 13 号——保荐业务》和《深圳证券交易 所上市公司自律监管指引第 2 号——创业板上市公司规范运作》等相关法律法规 的要求，对诺思格（北京）医药科技股份有限公司（以下简称"诺思格"、"公司"） 的控股股东、实际控制人、董事、高级管理人员及关键岗位人员等进行了 2025 年度持续督导培训，报告如下： 一、本次持续督导培训的基本情况 实施本次持续督导培训前，中金公司编制了培训讲义，提前要求公司董事、 高级管理人员等相关人员了解培训内容并参加。 （以下无正文） （本页无正文，为《中国国际金融股份有限公司关于诺思格（北京）医药科技股 份有限公司 2025 年度持续督导培训情况的报告》之签章页） 保荐代表人： 本次培训于 2026 年 3 月 9 日通过现场授课的方式对控股股东、实际控制人、 董事、高级管理人员及关键岗位人员进行了培训。中金公司从多个维度介绍了上 市公司股东、董事、高管减持股份 ...

Investment Rating - The report maintains a "Positive" investment rating for the clinical CRO industry [2] Core Insights - The clinical CRO industry is expected to enter a new growth cycle driven by improved supply-demand dynamics, with significant increases in order volume and pricing anticipated [3][5] - The domestic clinical CRO market is projected to reach a scale of 95.56 billion RMB by 2030, with a compound annual growth rate (CAGR) of approximately 13% from 2024 to 2030 [3][31] - The report highlights the increasing recognition of China's clinical trial quality on a global scale, suggesting that leading domestic CROs may expand internationally alongside innovative drug business development (BD) [3][38] Demand Summary - The demand for clinical CRO services is closely linked to the progress of clinical trials, with a notable recovery in innovative drug financing observed in 2025, where the financing amount reached 14.684 billion USD, a year-on-year increase of approximately 127% [3][17] - The number of clinical IND approvals in China for 2025 was 2,703, reflecting a year-on-year growth of about 19%, indicating a resurgence in clinical trial activities [3][27] - The report notes that the number of early-phase clinical trials (I and II) has also increased significantly, with I phase trials up by 13% and II phase trials up by 42% in 2025 [3][27] Supply Summary - The clinical CRO industry is characterized by a highly fragmented competitive landscape, with the leading company, Tigermed, holding only 12.8% market share as of 2023 [4][44] - The report indicates that many smaller companies are exiting the market due to previous demand shortages, leading to a consolidation of market share among larger players [4][46] - The average number of clinical trials per CRO company has increased by 20.6% year-on-year, indicating a trend towards greater concentration in the industry [4][55] Performance Tracking - The report anticipates a recovery in order prices for clinical CROs, with new order prices beginning to rise in 2025 after a period of decline [5][6] - The revenue trends for clinical CRO companies are showing signs of stabilization, with expectations for improved profitability as order prices recover [5][6] - Leading companies are expected to see significant improvements in their profit margins as new order prices increase [5][6] Recommended Companies - **Tigermed**: A leading global clinical CRO with a projected revenue of 6.66-7.68 billion RMB for 2025, representing a year-on-year growth of about 9% [7] - **Norse**: A specialized clinical CRO with a broad business scope, showing a year-on-year revenue growth of 24.48% in Q3 2025 [7] - **Prasis**: A leading SMO in China, with a significant increase in new contracts, showing a year-on-year growth of 40.12% in 2025 [7] - **Bohui Pharma**: Focused on one-stop R&D outsourcing, with a strong order reserve and consistent growth in new orders [7]

证券代码：301333 证券简称：诺思格 公告编号：2026-005 诺思格（北京）医药科技股份有限公司 关于持股 5%以上股东及特定股东减持股份 预披露公告 本公司股东宁波康运福股权投资有限公司、宁波瑞光创业投资 合伙企业（有限合伙）、宁波瑞明股权投资有限公司保证向本公司 提供的信息内容真实、准确、完整，没有虚假记载、误导性陈述或 重大遗漏。 本公司及董事会全体成员保证公告内容与信息披露义务人提 供的信息一致。 特别提示： 持有诺思格（北京）医药科技股份有限公司（以下简称"公司"）股份11,520,000 股（剔除回购股份数量后，约占本公司股本比例的12.00%）的股东宁波康运福股 权投资有限公司（以下简称"康运福公司"），计划在本减持计划公告发布之日 起15个交易日后的3个月内通过大宗交易方式减持本公司股份不超过1,088,000股 （占本公司股本的比例为1.13%）。 持有公司股份6,840,000股（剔除回购股份数量后，约占本公司股本比例的 7.13%）的股东宁波瑞光创业投资合伙企业（有限合伙）（以下简称"瑞光合伙 企业"），计划在本减持计划公告发布之日起15个交易日后的3个月内通过大宗 交易方式减持 ...

Core Viewpoint - The AI medical sector experienced a decline of 0.66% on February 11, with QianYuan Pharmaceutical leading the drop. The Shanghai Composite Index rose by 0.09%, while the Shenzhen Component Index fell by 0.35% [1]. Group 1: Market Performance - The closing price of QianYuan Pharmaceutical was 11.44, down by 4.67%, with a trading volume of 209,800 shares and a transaction value of 243 million [2]. - The AI medical sector saw a net outflow of 1.345 billion from major funds, while retail investors contributed a net inflow of 1.14 billion [2][3]. Group 2: Individual Stock Performance - YoukeDe (688158) closed at 37.54, up by 5.12%, with a trading volume of 631,000 shares and a transaction value of 2.36 billion [1]. - AidiTe (301580) closed at 55.18, up by 4.63%, with a trading volume of 46,100 shares and a transaction value of 251 million [1]. - SanNuo Biology (300298) closed at 18.54, up by 2.71%, with a trading volume of 105,200 shares and a transaction value of 194 million [1]. - The top decliners included QianYuan Pharmaceutical (300254) and KaiPu Biology (300639), with declines of 4.67% and 4.23%, respectively [2].

Core Viewpoint - Norsig (301333) has shown a fluctuating upward trend in its stock price over the past seven trading days, indicating positive market sentiment and potential investment interest [1][2] Group 1: Stock Performance - As of February 10, the stock price closed at 80.48 yuan, up 4.79% from the closing price of 76.80 yuan on February 5, with a price fluctuation range of 9.94% [1] - On February 6, the stock price experienced an intraday drop of 2.07% but closed at 79.04 yuan, marking a daily increase of 2.92% [1] - The stock price fell to 78.10 yuan on February 9, reflecting a decline of 1.19%, before rebounding with a 3.05% increase on February 10, with trading volume reaching 204 million yuan [1] Group 2: Technical Indicators - Technical analysis shows that the MACD indicator remains positive, while the KDJ indicator is at a high level, suggesting bullish momentum [1] - Short-term moving averages are in a bullish arrangement, and the upper pressure level of the Bollinger Bands is approximately 85.09 yuan [1] Group 3: Financing and Market Activity - As of February 9, Norsig's financing balance was 108 million yuan, with a financing purchase amount of 18.84 million yuan, indicating active market participation [2] - There have been no significant company announcements or operational events recently, suggesting a stable operational environment [2]

Investment Rating - The report maintains a "Buy" rating for the medical services industry, suggesting a positive outlook for investment opportunities in this sector [10][64]. Core Insights - The medical services sector has shown resilience, with a recent increase in the sector's PE ratio to 34.43X and PB ratio to 3.49X, indicating a positive trend in valuation metrics [4][29]. - The approval of internet medical first diagnosis trials in Beijing marks a significant regulatory breakthrough, potentially accelerating the online medical service process and providing new market opportunities for private medical institutions [5][62][63]. - The report highlights the importance of digital regulation and standardization in enhancing service capabilities for private medical institutions, particularly in consumer healthcare sectors like pediatrics and dermatology [5][62]. Summary by Sections Industry Performance - The pharmaceutical and biological sector increased by 0.14%, ranking 15th among 31 primary industries, outperforming the Shanghai Composite Index by 1.47 percentage points [2][12]. - The medical services sub-sector reported a 1.31% increase, closing at 6827.17 points, with a year-to-date performance of 41.41% [24][27]. Company Performance - Top-performing companies in the medical services sector include Meidisi (+18.0%), Tongce Medical (+8.1%), and Nuosige (+5.7%), while underperformers include Haoyuan Pharmaceutical (-6.2%) and Baicheng Pharmaceutical (-4.5%) [3][27]. Valuation Metrics - The medical services sector's PE ratio has increased by 0.56X from the previous week, while the PB ratio has risen by 0.06X, indicating a strengthening in market confidence [4][29]. Investment Recommendations - The report suggests focusing on high-growth areas such as ADC CDMO and peptide CDMO in the pharmaceutical outsourcing sector, as well as companies like WuXi AppTec and Haoyuan Pharmaceutical [10][64]. - It also recommends monitoring private medical service providers with compliance experience, such as Aier Eye Hospital, as they are expected to benefit from the evolving regulatory landscape [5][64].

Core Viewpoint - The ChiNext Medical Index (970082) closed at 3876.07 points on February 3, with a gain of 2.37% and a trading volume of 13.236 billion yuan, indicating positive market sentiment in the medical sector [1]. Group 1: Index Performance - The ChiNext Medical Index saw 49 constituent stocks rise, with NuoSiGe leading the gains at 8.76% [1]. - The index's turnover rate was 1.71%, reflecting moderate trading activity [1]. Group 2: Top Constituents - The top ten constituents of the ChiNext Medical Index include: - YuanEr Eye Hospital (sz300015) with a weight of 9.18% and a latest price of 11.04 yuan, up 1.28% [1]. - MaiRui Medical (sz300760) with a weight of 8.95% and a latest price of 188.15 yuan, up 0.56% [1]. - TaiGe Medical (sz300347) with a weight of 8.52% and a latest price of 63.20 yuan, up 4.97% [1]. - KangLong HuaCheng (sz300759) with a weight of 7.18% and a latest price of 29.61 yuan, up 2.10% [1]. - LePu Medical (sz300003) with a weight of 4.96% and a latest price of 17.83 yuan, up 1.89% [1]. - New Industry (sz300832) with a weight of 4.73% and a latest price of 54.50 yuan, up 2.60% [1]. - AiMeiKe (sz300896) with a weight of 4.49% and a latest price of 147.57 yuan, up 4.56% [1]. - YingKe Medical (sz300677) with a weight of 4.14% and a latest price of 40.55 yuan, up 1.38% [1]. - FuRui Medical (sz300049) with a weight of 3.55% and a latest price of 67.33 yuan, up 1.45% [1]. - HuaDa Gene (sz300676) with a weight of 3.15% and a latest price of 50.30 yuan, up 2.57% [1]. Group 3: Capital Flow - The net inflow of main funds into the ChiNext Medical Index constituents totaled 145 million yuan, while retail investors experienced a net outflow of 106 million yuan [1]. - The detailed capital flow indicates that TaiGe Medical had a main fund net inflow of 10.514 million yuan, while retail investors had a net outflow of 18.28% [2].

Market Performance - The medical services sector increased by 2.52% on February 3, with Norsig leading the gains [1] - The Shanghai Composite Index closed at 4067.74, up by 1.29%, while the Shenzhen Component Index closed at 14127.1, up by 2.19% [1] Top Gainers in Medical Services - Norsig (301333) closed at 78.98, up by 8.76% with a trading volume of 43,200 shares and a transaction value of 332 million [1] - Yinos (688710) closed at 61.07, up by 7.52% with a trading volume of 17,400 shares and a transaction value of 10.4 million [1] - Dean Diagnostics (300244) closed at 24.73, up by 6.69% with a trading volume of 447,200 shares and a transaction value of 1.084 billion [1] Market Capital Flow - The medical services sector saw a net inflow of 506 million from institutional investors, while retail investors experienced a net outflow of 4.12 billion [2][3] - The top stocks with significant institutional inflows included Tiger Medical (300347) with 103 million and Meinian Health (002044) with 86 million [3] Stock Performance Overview - The stock performance of various companies in the medical services sector showed a mix of gains and losses, with notable declines in stocks like Haocen Medical (002622) down by 1.97% [2] - The trading volume and transaction values varied significantly across different companies, indicating diverse investor interest [2]