证券代码：301333 证券简称：诺思格 公告编号：2025- 055 诺思格（北京）医药科技股份有限公司 关于召开 2025 年第三次临时股东大会的通知 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 根据诺思格（北京）医药科技股份有限公司（以下简称"公司"）第五届 董事会第十五次会议决议，公司董事会定于 2025 年 12 月 29 日（星期一）以 现场表决和网络投票相结合的方式召开公司 2025 年第三次临时股东大会，现 将本次股东大会的有关事项通知如下： 一、召开会议的基本情况 1、股东会届次：2025 年第三次临时股东大会 6、会议的股权登记日：2025 年 12 月 23 日 7、出席对象： （1）截至 2025 年 12 月 23 日（股权登记日）下午收市时，在中国证券登 2、股东会的召集人：董事会 3、本次会议的召集、召开符合《中华人民共和国公司法》《深圳证券交 易所创业板股票上市规则》《深圳证券交易所上市公司自律监管指引第 2 号— —创业板上市公司规范运作》等法律、行政法规、部门规章、规范性文件及 《公司章程》的有关规定。 4、会议时间： ...

证券代码：301333 证券简称：诺思格 公告编号：2025-051 诺思格（北京）医药科技股份有限公司 第四届监事会第十二次会议决议公告 本公司及监事会全体成员保证信息披露的内容真实、准确、完 整，没有虚假记载、误导性陈述或重大遗漏。 一、监事会会议召开情况 诺思格（北京）医药科技股份有限公司（以下简称"公司"）第四届监事会 第十二次会议于2025年12月9日在公司会议室以现场结合通讯方式召开。会议通 知已于2025年12月2日以电子邮件及专人送达等方式送达全体监事。本次会议应 出席监事3人，实际出席监事3人。会议由监事会主席关虹主持。会议召开符合有 关法律、法规、规章和《诺思格（北京）医药科技股份有限公司章程》（以下简 称"《公司章程》"）的规定。 二、监事会会议审议情况 （一）审议通过《关于调整组织架构并修订<公司章程>的议案》 表决情况：3票同意；0票弃权；0票反对。 经审议，监事会认为：本次公司调整组织架构并修订《公司章程》等事项系 公司为全面贯彻落实最新法律、法规及规范性文件要求，结合公司实际情况做出 的决定，有利于进一步完善公司治理结构。调整后，公司监事会相关制度相应废 止或做出相应修订，并由董 ...

证券代码：301333 证券简称：诺思格 公告编号：2025-050 诺思格（北京）医药科技股份有限公司 第五届董事会第十五次会议决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确、完 整，没有虚假记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 诺思格（北京）医药科技股份有限公司（以下简称"公司"）第五届董事会 第十五次会议（以下简称"本次会议"）于2025年12月9日在公司会议室以现场结 合通讯方式召开。会议通知已于2025年12月2日以电子邮件及专人送达等方式送 达全体董事。本次会议应出席董事9人，实际出席董事9人。会议由董事长WU JIE （武杰）先生主持，会议的召开符合有关法律、法规、规章和《诺思格（北京） 二、董事会会议审议情况 （一）审议通过《关于调整组织架构并修订<公司章程>的议案》 表决情况：9票同意；0票弃权；0票反对。 根据《中华人民共和国公司法》（以下简称"《公司法》"）《关于新<公司法> 配套制度规则实施相关过渡期安排》《上市公司章程指引》等有关法律、法规和 规范性文件的规定，并结合公司实际情况，公司将不再设监事会，监事会的职权 由董事会审计委员会行使，《监事会议事规则 ...

Market Overview - The medical services sector increased by 0.56% on November 25, with ST Zhongzhu leading the gains [1] - The Shanghai Composite Index closed at 3870.02, up 0.87%, while the Shenzhen Component Index closed at 12777.31, up 1.53% [1] Top Gainers in Medical Services - ST Zhongzhu (600568) closed at 2.57, up 4.90% with a trading volume of 53,900 shares and a turnover of 13.85 million yuan [1] - Chengda Pharmaceutical (301201) closed at 47.78, up 2.97% with a trading volume of 112,700 shares and a turnover of 540 million yuan [1] - Boji Pharmaceutical (300404) closed at 10.10, up 2.75% with a trading volume of 108,600 shares and a turnover of 10.9 million yuan [1] Top Losers in Medical Services - Jiuzhou Pharmaceutical (603456) closed at 18.75, down 0.85% with a trading volume of 181,100 shares and a turnover of 343 million yuan [2] - Tongce Medical (600763) closed at 41.95, down 0.66% with a trading volume of 49,600 shares and a turnover of 210 million yuan [2] - Yingkang Life (300143) closed at 10.12, down 0.49% with a trading volume of 44,700 shares and a turnover of 4.56 million yuan [2] Capital Flow Analysis - The medical services sector experienced a net outflow of 113 million yuan from institutional investors, while retail investors saw a net inflow of 30.37 million yuan [2][3] - Major stocks like WuXi AppTec (603259) had a net inflow of 67.13 million yuan from institutional investors, while Sunshine Nuohua (688621) saw a net outflow of 2.29 million yuan from retail investors [3] Summary of Individual Stock Performance - Sunshine Nuohua (688621) had a net inflow of 38.24 million yuan from institutional investors, but a net outflow of 3.59 million yuan from retail investors [3] - Chengda Pharmaceutical (301201) also saw a significant net inflow of 36.45 million yuan from institutional investors, with a net outflow of 13.58 million yuan from retail investors [3] - New Mileage (002219) had a net inflow of 14.15 million yuan from institutional investors, while retail investors experienced a net outflow of 6.70 million yuan [3]

Core Insights - The oncology CRO (Contract Research Organization) services focus on specialized outsourcing for cancer drug development, addressing challenges such as long R&D cycles, high difficulty, and significant risks, thereby efficiently advancing drugs from preclinical stages to market [1][5][4] - The global oncology CRO services market is projected to grow from $7.2 billion in 2020 to $16.2 billion in 2024, with an expected increase to $18.6 billion by 2025 [1][5] - The oncology CRO sector is a highly specialized segment within the broader CRO market, providing comprehensive or partial outsourcing services for clinical trials of anti-cancer drugs [3][4] Industry Definition and Segmentation - CROs provide professional services to pharmaceutical companies and research institutions throughout the drug development process, covering drug discovery, preclinical research, clinical trials, data management, and regulatory submissions [2][4] - Oncology CRO services include preclinical, clinical, and post-marketing services, with preclinical services further divided into hematological cancers, solid tumors, and others [3][4] Current Industry Status - The CRO industry is experiencing significant growth, reflecting a revitalization of the entire pharmaceutical innovation ecosystem [4][5] - The global CRO services market is expected to expand from $62 billion in 2020 to $98.4 billion in 2024, with China's market growing from $7 billion to $10.5 billion in the same period [5] Industry Value Chain - The upstream of the oncology CRO service industry includes basic chemical raw materials, pharmaceutical intermediates, and various scientific instruments [6] - The midstream consists of oncology CRO service providers, which are the core of the industry chain, characterized by technology and talent intensity [6] - The downstream includes demand-side entities such as pharmaceutical and biotechnology companies, medical institutions, and clinical trial researchers [6] Competitive Landscape - The oncology CRO industry in China features a dynamic and layered competitive landscape, with significant differences in scale, service range, client base, and core competencies among companies [9][10] - Key players in the oncology CRO sector include WuXi AppTec, Kanglong Chemical, and others, with a focus on comprehensive services from target validation to new drug registration [10][11] Development Trends - The oncology CRO service industry reflects the pulse of China's pharmaceutical R&D, transitioning from a traditional labor-intensive service sector to a modern, technology-driven, data-intensive industry [13] - The trend towards intelligent systems in clinical CRO services is seen as an inevitable evolution [13]

Core Viewpoint - The domestic R&D demand is showing marginal improvement, driven by the overseas expansion of innovative drugs, leading to a recovery in R&D orders and stabilization of industry prices after a decline in 2023. The CRO sector is expected to see better performance growth by 2026, while the CDMO industry has also reached a bottom and is poised for continued strong growth due to robust demand for new molecules and new orders [1][2][3]. CRO Sector - The domestic R&D demand is recovering, with an increase in orders and stabilization of prices, indicating a clear upward trend for CRO companies. Clinical CROs like Tigermed, Nossan, and Prasis are expected to see revenue growth turning positive by 2025, with significant contributions from overseas business [2][3]. - The recognition of domestic CRO clinical data is improving, which is beneficial for companies like Tigermed [2]. CDMO Sector - The CDMO sector has seen a recovery in performance, with new orders continuing to improve quarterly. The global demand for innovative drug R&D is driving growth in new orders and backlog [3]. - The industry is benefiting from increased capacity utilization and profitability, with a strong certainty of performance and profit growth expected to continue into 2026 [3]. Life Sciences Sector - The life sciences upstream sector is experiencing a dual drive from domestic substitution and overseas expansion, with urgent demand for domestic alternatives in areas like cell culture media and biological reagents. Companies are expected to capture market share through new product categories and cost-effective offerings [4]. - The demand for specific segments such as drug efficacy, antibodies, and proteins is increasing, indicating a clear long-term growth logic for the industry [4]. API Sector - The raw material pharmaceutical industry is currently in a phase of price bottoming and supply surplus, with traditional product performance under pressure. However, companies are extending their business into generics, innovative drugs, and specialty APIs, which may lead to value reconstruction through business structure optimization [5]. - The valuation of raw material pharmaceutical companies is at a low point, presenting opportunities based on changes in new business layouts [5]. Investment Recommendations - For clinical and preclinical CROs, companies like Tigermed, Nossan, and Yinos are recommended due to the gradual recovery of the industry and expected improvement in order structure [6]. - In the CDMO sector, companies such as WuXi AppTec, WuXi Biologics, and others with strong fundamentals and capacity advantages are highlighted for their potential benefits from industry recovery and high demand for new molecules [6]. - In the life sciences upstream sector, companies like Baitai Biotechnology and others are recommended due to accelerated domestic substitution and strong overseas growth [6]. - Companies like Pro Pharma and Huahai Pharmaceutical are noted for their new business layouts that are expected to contribute significant value increments [6].

Group 1 - A total of 59 stocks in the A-share market experienced block trading today, with a total transaction value of 1.335 billion yuan [1] - The top three stocks by transaction value were Shanxi Fenjiu (186 million yuan), Hanrui Cobalt (109 million yuan), and Jinkong Electric (80.34 million yuan) [1] - Among the stocks, 9 were traded at par, 5 at a premium, and 45 at a discount; the stocks with the highest premium rates were Bosi Software (19.41%), Jiaxun Feihong (16.8%), and Yongtai Energy (11.11%) [1] - The stocks with the highest discount rates included Zhi De Mai (20.12%), Wens Foodstuff Group (19.6%), and Nuo Si Ge (19.44%) [1] Group 2 - The ranking of institutional buy amounts was led by Shanxi Fenjiu (167 million yuan), followed by Keli'er (37.41 million yuan) and Sanfeng Intelligent (29.27 million yuan) [1] - Other notable institutional buys included Action Education (18.20 million yuan), Chunfeng Power (12.87 million yuan), and Zhi De Mai (11.47 million yuan) [1] - The top stock sold by institutional special seats was Jinkong Electric (80.34 million yuan), followed by Maiwei Co. (3.21 million yuan) [2]

Summary of Key Points Core Viewpoint - On November 18, a block trade of 42,800 shares of Norsg was executed at a price of 48.50 yuan, representing a discount of 19.44% compared to the market closing price of 60.20 yuan, with a total transaction value of 2.0758 million yuan, accounting for 1.23% of the total trading volume for the day [1][2]. Group 1: Transaction Details - The block trade involved 42,800 shares of Norsg at a price of 48.50 yuan per share [2]. - The total transaction amount was 2.0758 million yuan [1][2]. - The trade was executed by Fangzheng Securities and Huafu Securities [2].

Market Overview - The medical services sector declined by 0.47% on November 14, with the digital human sector leading the drop [1] - The Shanghai Composite Index closed at 3990.49, down 0.97%, while the Shenzhen Component Index closed at 13216.03, down 1.93% [1] Stock Performance - Notable declines in individual stocks include: - Digital Human: closed at 17.28, down 4.85% with a trading volume of 80,400 shares and a turnover of 1.411 million [1] - Haoyuan Pharmaceutical: closed at 77.20, down 3.54% with a trading volume of 30,800 shares and a turnover of 2.4212 million [1] - Yinos: closed at 48.69, down 2.62% with a trading volume of 14,300 shares and a turnover of 7132.217 [1] - Other notable declines include Taige Pharmaceutical, MediX, and WuXi AppTec, all showing declines between 1.28% and 2.08% [1] Capital Flow - The medical services sector experienced a net outflow of 238 million yuan from institutional investors, while retail investors saw a net inflow of 181 million yuan [3] - Notable capital flows for specific stocks include: - Ruizhi Pharmaceutical: net inflow of 38.93 million yuan from institutional investors, but net outflows from retail and speculative investors [3] - Chengda Pharmaceutical: net inflow of 37.96 million yuan from institutional investors, with significant outflows from speculative investors [3] - Other stocks like Sanbo Brain Science and Jinyu Medical also showed varying net inflows and outflows among different investor types [3]

Core Insights - Norska's stock price decreased by 2.00% on November 12, trading at 61.24 CNY per share with a market capitalization of 5.915 billion CNY [1] - The company has seen a year-to-date stock price increase of 22.89%, but a recent decline of 7.13% over the last five trading days [1] Financial Performance - For the period from January to September 2025, Norska achieved a revenue of 607 million CNY, representing a year-on-year growth of 8.09% [2] - The net profit attributable to shareholders for the same period was 95.5668 million CNY, reflecting a year-on-year increase of 13.21% [2] Business Overview - Norska, established on August 22, 2008, specializes in clinical trial operation services, clinical trial site management services, biological sample testing services, data management and statistical analysis services, clinical trial consulting services, and clinical pharmacology services [2] - The revenue composition of Norska's main business includes: 39.25% from clinical trial operation services, 34.10% from clinical trial site management services, 13.30% from data management and statistical analysis services, 8.45% from biological sample testing services, 3.74% from clinical pharmacology services, and 1.16% from clinical trial consulting services [2] Shareholder Information - As of September 30, 2025, Norska had 8,734 shareholders, a decrease of 16.18% from the previous period, with an average of 6,545 circulating shares per shareholder, an increase of 19.30% [2] - The company has distributed a total of 49.4969 million CNY in dividends since its A-share listing [3]