Core Viewpoint - Veteran investor David Roche predicts a bear market in 2025 driven by smaller-than-expected rate cuts, a slowing U.S. economy, and an artificial intelligence bubble [1][2][3] Group 1: Federal Reserve and Interest Rates - Roche expects the Federal Reserve to resist reducing rates to the market's desired level of 3.50%, with the Fed's median forecast for 2025 at 4.1% [2] - Market participants anticipate rates below 4.1% by September 2025, according to the CME FedWatch Tool [2] Group 2: Economic Growth and Corporate Profits - Roche warns that corporate profits will not meet expectations due to a slowing economy [2] - The anticipated economic slowdown is expected to contribute to a bear market [3] Group 3: Artificial Intelligence Sector - The AI sector is viewed as having "entered bubble terrain decisively," which is expected to contribute to slower economic growth [3] - Roche predicts that the AI bubble will exit its current state over the next six months, further impacting the economy [3] Group 4: Market Predictions - Roche forecasts a bear market of approximately minus 20% in 2025, potentially starting at the end of 2024 [3] - This prediction does not take into account the outcome of the U.S. Presidential election in November [3]

Approval is based on data from two Phase III studies in branch and central retinal vein occlusion (RVO) showing early and sustained vision improvements non-inferior to aflibercept, and robust retinal drying with Vabysmo Additional submitted data shows that up to 60% of people receiving Vabysmo were able to extend treatment intervals to three or four months Vabysmo is already approved in several countries, including the US and Japan, for RVO and in nearly 100 countries for people with nAMD and DME RVO is the ...

"We are fast-tracking the clinical development of our obesity portfolio with the aim to bring these medications to patients faster than anticipated. We will communicate updated timelines when appropriate," a Roche spokesperson told FOX Business. HIMS & HERS ROLLS OUT WEIGHT-LOSS SHOTS MUCH CHEAPER THAN OZEMPIC, WEGOVY GLP-1 agonists are a class of Type 2 diabetes drugs that improve blood sugar control but may also lead to weight loss. Semaglutide, which is the active ingredient in Novo Nordisk's Wegovy and ...

Swiss pharmaceutical giant Roche said Monday it is accelerating the development of its Wegovy rival weight loss drugs following promising early stage trial data. The company's two obesity drug candidates are progressing to the next phase of trials and could come to market within the next few years, providing a potential pill-based alternative to Novo Nordisk's Wegovy and Eli Lilly's Zepbound weight loss injections. "We are fast-tracking the clinical development of our obesity portfolio with the aim to bring ...

Roche's latest breakthrough could be a game changer, but it's still too early to say. That's just what happened after an announcement by Roche Holding (RHHBY 3.03%) on July 16. Shares of Novo Nordisk (NVO -0.88%), Eli Lilly (LLY -2.02%), Structure Therapeutics, Altimmune, and Viking Therapeutics all took a hit. Biotechs with clinical-stage weight loss candidates, specifically Viking and Altimmune, fell by nearly 13%, with larger players dropping by more than 4% even while the market was mostly flat. The mar ...

Basel, 29 July 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the completion of the acquisition of LumiraDx's Point of Care technology, following the receipt of all required antitrust and regulatory clearances. Roche will now embark on the full integration of the company's innovative multi-assay point of care platform and the related R&D, operational and commercial sites into its global organisation. "Access to diagnostic testing is critical for the delivery of healthcare worldwide and we are con ...

Roche HY 2024 results Thomas Schinecker Chief Executive Officer HY 2024: Strong business performance in both divisions • Diagnostics regulatory: cobas c703 and ISE neo (EU), cobas Liat Respiratory Panel FDA EUA, cobas pro serology solution (FDA), Accu-Chek SmartGuide CGM (EU), VENTANA Kappa Lambda Dual ISH mRNA Probe Cocktail (EU), HPV self-collection solution (FDA) • Pivotal readouts: Ph III (REGENCY) Gazyva in LN and Ph III (SKYSCRAPER-01) tiragolumab in 1L NSCLC Roche Any statements regarding earnings pe ...

Financial Data and Key Metrics Changes - Group sales increased by 8%, with a 5% increase excluding COVID-19 impacts, and a significant growth of 9% in Q2 [4][11] - Core operating profit increased by 11%, leading to a core operating margin increase of almost 2 percentage points [5][42] - Core EPS grew by 9%, and operating free cash flow also grew by 9% [6][37] - IFRS net income declined by 4% in constant rates, primarily due to impairments and higher interest expenses [44][75] Business Line Data and Key Metrics Changes - Pharma sales reached CHF22.6 billion, growing at 5% at constant exchange rates and 8% excluding Ronapreve [50] - Diagnostics division sales increased by 5% to CHF7.21 billion, driven by a 9% growth in the base business [98][101] - Core operating profit for Diagnostics increased by 22% at constant exchange rates, with a margin of 22% [102] Market Data and Key Metrics Changes - Sales in Japan were impacted by a base effect of about CHF600 million and mandatory price cuts, leading to a 5% decline when excluding Ronapreve [50] - The U.S. market for Hemlibra saw a return to positive growth of 3% in Q2, while overall sales in hematology reached CHF3.8 billion with 10% growth [67] - Neurology franchise achieved CHF4.6 billion in sales for the first half, representing a 13% growth [68] Company Strategy and Development Direction - The company revised its 10-year goals and clarified its strategy across five therapeutic areas [24][25] - Focus on digital health efforts, particularly in generative AI, to strengthen core business [26][27] - Continued investment in R&D with a focus on high medical value assays and technologies [25][76] Management Comments on Operating Environment and Future Outlook - Management expressed a positive outlook for 2024, expecting continued strong growth in the base business with reduced COVID effects [34][80] - The company anticipates that the momentum will carry into 2025, confirming guidance for mid-single-digit sales growth [49][80] - Management highlighted the importance of maintaining and potentially extending margins through effective resource allocation [80][81] Other Important Information - The company achieved several key regulatory approvals and positive readouts in the second quarter, including for Ocrevus and Alecensa [6][14] - The company is entering new markets, such as blood screening in serology, and launching innovative products like continuous glucose monitoring [7][21] - The company plans to file for Lunsumio subcut in the second half of 2024 and has seen positive early sales for Elevidys [63][65] Q&A Session Summary Question: What are the expectations for Diagnostics margins in the second half? - Management indicated strong growth and margins in Diagnostics, with expectations to potentially exceed 20% for the year [97] Question: What is driving the growth in Evrysdi? - Growth in Evrysdi was driven by a one-time tender purchase and expansion of the patient population, particularly among adults who are currently untreated [97] Question: How is the company managing its R&D pipeline? - The company is focused on removing underperforming assets from its pipeline while investing in high-potential candidates, ensuring a robust and efficient R&D process [76][79]

The company reports under two divisions — Pharmaceuticals and Diagnostics. All growth rates mentioned below are on a year-over-year basis and at CER. Sales in the Pharmaceuticals Division improved 5% in the first half to CHF 22.6 billion, driven by strong growth in demand for its key drugs. Roche's shares have risen 6.4% year to date compared with the industry's growth of 20%. Sales of Ocrevus, used to treat two types of multiple sclerosis, increased 8% year over year to CHF 3.3 billion. Second-quarter reve ...

INDIANAPOLIS and CHICAGO, July 25, 2024 /PRNewswire/ -- Roche (SIX: RO, ROG; OTCQX: RHHBY) will showcase a laboratory of the future exhibit at the 2024 Association for Diagnostics & Laboratory Medicine (ADLM) Scientific Meeting and Clinical Lab Expo, July 28 through August 1 in Chicago. Attendees will have the opportunity to experience how Roche's growing portfolio of integrated systems and data solutions optimizes resources and simplifies and streamlines operations while driving better health outcomes. "La ...