Group 1 - The core business of Haohai Biological Technology is primarily in the pharmaceutical manufacturing sector, accounting for 99.83% of its revenue, while other businesses contribute only 0.17% [1] Group 2 - As of August 15, 2025, Haohai Biological Technology has completed its share repurchase program, acquiring approximately 1.83 million A-shares, which represents 0.79% of the total share capital of about 233 million shares [3] - The highest price for the repurchased shares was 63.58 CNY per share, the lowest was 49.25 CNY per share, and the average repurchase price was 56.7 CNY per share, with a total expenditure of approximately 104 million CNY [3]

证券代码：688366 证券简称：昊海生科 公告编号：2025-037 上海昊海生物科技股份有限公司 关于第二期 A 股股份回购实施结果公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 重要内容提示： | 回购方案首次披露日 | 2024/8/17 | | | | | | | --- | --- | --- | --- | --- | --- | --- | | 回购方案实施期限 | 年 月 2024 8 8 | 16 | 日~2025 | 年 | 月 | 日 15 | | 预计回购金额 | 10,000.00万元~20,000.00万元 | | | | | | | 回购价格上限 | 88.72元/股（调整前为 89.71 | | | | | 元/股） | | 回购用途 | □减少注册资本 √用于员工持股计划或股权激励 | | | | | | | | □用于转换公司可转债 | | | | | | | | □为维护公司价值及股东权益 | | | | | | | 实际回购股数 | 1,832,421股 | | | | | ...

Group 1 - The company, Haohai Biological Technology (688366.SH), has completed its current share repurchase program as of August 14, 2025 [1] - A total of 1.8324 million A-shares were repurchased, accounting for 0.79% of the company's total share capital [1] - The highest repurchase price was 63.58 CNY per share, while the lowest was 49.25 CNY per share, with an average repurchase price of 56.70 CNY per share [1] - The total amount spent on the repurchase was 104 million CNY, excluding stamp duty and transaction commissions [1]

Group 1 - The core viewpoint of the articles highlights the financial performance and market position of Haohai Biological Technology Co., Ltd. in the medical device industry [1][2] - As of August 15, Haohai's stock closed at 55.18 yuan, with a rolling PE ratio of 31.06 times and a total market capitalization of 12.834 billion yuan [1] - The average PE ratio for the medical device industry is 56.58 times, with a median of 39.97 times, placing Haohai at the 60th position in the industry ranking [1][2] Group 2 - As of February 29, 2020, Haohai had 7,605 shareholders, an increase of 918 from the previous count, with an average holding value of 352,800 yuan and an average shareholding of 27,600 shares [1] - The company's main business includes the research, production, and sales of medical devices and pharmaceuticals, with key products such as ophthalmic viscoelastic devices, artificial lenses, and hyaluronic acid [1] - In the latest quarterly report for Q1 2025, Haohai reported revenue of 619 million yuan, a year-on-year decrease of 4.25%, and a net profit of 90.31 million yuan, down 7.41%, with a gross profit margin of 69.52% [1]

Group 1 - The core viewpoint of the articles highlights the financial performance and market position of Haohai Biological Technology Co., Ltd. in the medical device industry, indicating a decline in revenue and profit in the latest quarterly report [1][2] - As of August 14, Haohai's closing stock price was 54.63 yuan, with a PE ratio of 30.75 times, and a total market capitalization of 12.706 billion yuan [1] - The average PE ratio for the medical device industry is 55.76 times, with a median of 39.14 times, positioning Haohai at the 61st rank within the industry [1][2] Group 2 - The latest quarterly report for Q1 2025 shows Haohai achieved an operating revenue of 619 million yuan, a year-on-year decrease of 4.25%, and a net profit of 90.3121 million yuan, down 7.41% year-on-year, with a gross profit margin of 69.52% [1] - As of February 29, 2020, Haohai had 7,605 shareholders, an increase of 918 from the previous count, with an average holding value of 352,800 yuan and an average holding quantity of 27,600 shares [1]

Investment Rating - The investment rating for the company is "Accumulate" [3][17]. Core Views - The company demonstrates steady revenue growth, balancing product expansion and brand promotion, with significant R&D advantages expected to lead to innovative products in gynecology, hair care, and serious medical fields [1]. - The company has established a mature branding strategy and is building a global system for its products, with multiple patents approved in various regions [9]. Financial Summary - Total revenue is projected to grow from 780 million in 2023 to 3,534 million by 2027, reflecting a compound annual growth rate (CAGR) of 28.2% [2][10]. - Net profit attributable to the parent company is expected to increase from 300 million in 2023 to 1,814 million in 2027, with a CAGR of 29.4% [2][10]. - Earnings per share (EPS) is forecasted to rise from 2.61 yuan in 2023 to 15.77 yuan in 2027 [2][10]. - The return on equity (ROE) is projected to remain strong, starting at 31.4% in 2023 and declining to 34.2% by 2027 [2][10]. Market Data - The target price for the company's stock is set at 402.74 yuan [3]. - The stock has a 52-week price range of 151.90 to 577.50 yuan [4]. - The total market capitalization is approximately 34.86 billion yuan [4]. Business Segments - The medical device segment reported revenue of 708 million in the first half of 2025, a year-on-year increase of 33.41% [9]. - The functional skincare segment saw a significant revenue increase of 152.39%, reaching 121 million in the same period [9]. - The raw materials segment experienced a modest growth of 12.40%, with revenue of 27 million [9]. Operational Highlights - The company has successfully obtained patents for its collagen products in Brazil and FDA certifications for several skincare products in the U.S. [9]. - Marketing strategies include collaborations with leading medical institutions and participation in academic summits and international expos to enhance brand recognition [9].

Summary of Key Points Core Viewpoint - The investment and financing landscape of the medical beauty injection materials industry in China is relatively mature, with a significant number of investment events and a focus on scientific research and technology services. Group 1: Financing Status - As of June 2025, there have been 39 investment events in the medical beauty injection materials industry, indicating a mature investment environment [2][4]. - The majority of financing events are concentrated in Shandong and Jiangsu provinces, with Shandong having 8 events and Jiangsu 7 events [4]. Group 2: External Investment Layout - Representative companies in the medical beauty injection materials industry have engaged in numerous external investment events, primarily focusing on scientific research and technology services, which account for approximately 58% of their investments [14][13]. - Other sectors of investment include manufacturing (18%) and wholesale and retail (8%) [14]. Group 3: Mergers and Acquisitions - The level of mergers and acquisitions in the medical beauty injection materials industry is relatively low, with notable participation from real estate companies. For instance, Lushang Development acquired 100% of Shandong Furuida Pharmaceutical Group in 2018 to enter the medical beauty sector [16].

Core Insights - The coronary artery stent market in China is projected to reach approximately $7.0 billion by 2024, with a year-on-year growth of 6.4% [5][6]. Market Overview - In 2023, 8.368 million patients were hospitalized for coronary heart disease, with 1.901 million undergoing PCI (Percutaneous Coronary Intervention), where stent placement accounted for 81.2% of these procedures [3][6]. Product Structure - Drug-eluting stents (DES) dominate the market, expected to account for 69% of market revenue in 2024. The increasing prevalence of hypertension and diabetes due to aging populations and lifestyle changes is driving demand for DES [7][6]. Development Trends - **Material Innovation**: New alloy materials such as platinum-chromium and nickel-titanium are increasingly used due to their superior mechanical properties and biocompatibility. Biodegradable materials like polylactic acid and polycaprolactone are also being adopted to mitigate long-term foreign body reaction risks [11]. - **Functional Innovation**: Improvements in drug carriers for drug-eluting stents enhance drug release efficiency, reducing the risk of late thrombosis. Smart stents integrating sensors can monitor physiological parameters in real-time and adjust drug release accordingly [11].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容而產生或因依 賴該等內容而引致的任何損失承擔任何責任。 （股份代號：6826） 董事會會議召開日期 上海昊海生物科技股份有限公司（「本公司」）董事會（「董事會」）茲通告謹定於二 零二五年八月二十二日（星期五）舉行董事會會議，藉以（其中包括）審議及通過本 公司及其附屬公司截至二零二五年六月三十日止六個月的中期業績及其發佈，以 及考慮派發中期股息（如有）。 承董事會命 上海昊海生物科技股份有限公司 主席 侯永泰 中國上海，二零二五年八月十二日 Shanghai Haohai Biological Technology Co., Ltd.* 上海昊海生物科技股份有限公司 （於中華人民共和國註冊成立的股份有限公司） 於本公告日期，本公司之執行董事為侯永泰博士、吳劍英先生、陳奕奕女士及唐 敏捷先生；本公司之非執行董事為游捷女士、黃明先生及魏長征先生；及本公司 之獨立非執行董事為沈紅波先生、姜志宏先生、蘇治先生及楊玉社先生。 * 僅供識別 ...

Core Viewpoint - The recent announcement by Fosun Pharma regarding the approval of RT002 (DaxibotulinumtoxinA) for treating adult cervical dystonia indicates a potential expansion of botulinum toxin applications beyond aesthetic uses into therapeutic areas [1][4]. Industry Overview - The primary application of botulinum toxin in the domestic market remains in the medical aesthetics sector, where it is highly favored for procedures such as wrinkle reduction, facial slimming, and shaping [2][3]. - In 2020, botulinum toxin accounted for approximately 58% of the global injectable product market, surpassing hyaluronic acid, which held a 40% share [2]. Competitive Landscape - Numerous medical aesthetic companies are actively developing botulinum toxin products through acquisitions, independent research, and exclusive licensing agreements [3]. - The market currently features four major products, with competition expected to intensify as more players enter the market [3]. Therapeutic Potential - The therapeutic applications of botulinum toxin are significant, with potential uses in treating conditions such as strabismus, muscle tension disorders, migraines, obesity, and excessive sweating, spanning various medical specialties [5][6]. - Compared to developed countries, the range of approved indications for botulinum toxin in China is relatively limited, suggesting substantial growth potential in the market as more indications undergo clinical trials [6]. Development Challenges - The development cycle for botulinum toxin is lengthy and costly, with high barriers to entry due to regulatory scrutiny and the complexity of industrial production processes [7]. - The typical timeline for a drug to move from development to approval can take 8-10 years, highlighting the significant investment required in both time and resources [7].