Core Viewpoint - The article highlights a significant increase in respiratory infections among children during the autumn and winter seasons, with various pathogens circulating, particularly influenza and rhinovirus, leading to a rise in outpatient visits at children's hospitals [1][2]. Group 1: Respiratory Infection Trends - There has been a notable rise in the number of outpatient visits for respiratory infections in children's hospitals, with symptoms such as persistent cough, runny nose, and fever being common among affected children [1]. - According to the China CDC, influenza has become the leading pathogen in outpatient settings, with a positive detection rate of 17.5% for influenza-like cases [1]. - The infection rates for rhinovirus are also high, particularly among children aged 14 and below, while respiratory syncytial virus (RSV) is showing an upward trend in northern provinces [1]. Group 2: Symptoms and Treatment - Common symptoms of respiratory viral infections include fever, cough, phlegm, sore throat, sneezing, and runny nose, but different viruses exhibit distinct characteristics [2]. - RSV primarily affects infants under 2 years old, presenting with symptoms like runny nose, low fever, and cough, while severe cases may lead to respiratory distress [2]. - Influenza typically presents with more severe systemic symptoms, whereas rhinovirus infections are generally milder, resembling common colds [2]. Group 3: Treatment Guidelines - There are significant differences in treatment approaches for various viral infections; both rhinovirus and RSV lack specific antiviral medications, and treatment focuses on supportive care [2]. - For confirmed influenza cases, prompt administration of antiviral medications can effectively alleviate symptoms, but these medications are not beneficial for other viral infections [2]. - The use of antibiotics is discouraged for any viral infections, as they do not provide any benefit [2]. Group 4: Influenza Virus Characteristics - Current circulating influenza strains are predominantly the H3N2 subtype, which accounts for over 98% of detected cases [3]. - The H3N2 subtype is a common seasonal flu strain, and vaccination is emphasized as the most effective and economical method to prevent severe illness from influenza [3]. - Available influenza vaccines are effective against the currently circulating H3N2 strain [3].

Core Insights - The flu activity in China has significantly increased, with most provinces entering the flu epidemic period, particularly in regions like South China, Southwest, Northeast, and Northwest where some provinces have reached moderate epidemic levels [1][3]. Group 1: Flu Activity Trends - Sichuan Province has officially entered the flu epidemic period, with a rapid increase in case numbers [2]. - The flu epidemic this year has emerged earlier and is expected to peak above the recent average levels in Hunan Province [2]. - During the 44th week of 2025, the percentage of flu-like cases reported in emergency departments was 4.7%, with flu virus detection rates at 17.5% [2][3]. Group 2: Respiratory Virus Monitoring - A total of 347 flu-like case outbreaks were reported nationwide in the 44th week of 2025, with southern provinces reporting 350 outbreaks, significantly higher than the 120 outbreaks in the same period of 2024 [3]. - The detection rates of respiratory syncytial virus (RSV) are rising in northern provinces, while southern provinces show fluctuating declines [4]. - The positive detection rates for enteroviruses have decreased, while the rates for rhinoviruses remain stable, particularly among children aged 14 and under [4]. Group 3: Public Health Recommendations - Health monitoring in key institutions such as kindergartens, schools, and nursing homes is advised to promptly identify and manage outbreaks [6]. - The public is encouraged to take personal protective measures, including flu vaccinations for individuals aged six months and older without contraindications [6]. - Recommendations include wearing masks in crowded places and maintaining good hygiene practices to reduce the risk of infection [7].