Core Viewpoint - The domestic medical beauty industry is undergoing significant changes, with major players experiencing a decline in performance due to market shifts and increased competition from new regenerative materials like collagen and "童颜针" (youthful needle) [4][7][14]. Group 1: Industry Performance - The three major companies in the medical beauty sector, including 华熙生物, 爱美客, and 昊海生科, reported substantial declines in revenue and net profit, with 爱美客's revenue dropping by 21.59% to 12.99 billion yuan and net profit decreasing by 29.57% to 7.89 billion yuan in the first half of 2024 [7][8]. - 爱美客's core products, including "嗨体" and "濡白天使," saw revenue declines of 23.79% and 23.99%, respectively, despite maintaining high gross margins of over 90% [6][7]. Group 2: Market Trends - The introduction of "童颜针," particularly the imported product 艾塑菲, has gained rapid popularity, with sales reaching 20,000 units and contributing over 800 million yuan in revenue within two months of its launch [5][17]. - The shift towards regenerative materials is evident, as "童颜针" offers longer-lasting effects and a different mechanism compared to traditional hyaluronic acid fillers, which are facing price declines due to increased competition [16][17]. Group 3: Strategic Moves - 爱美客's acquisition of REGEN, a Korean medical beauty company, for 1.386 billion yuan marks the largest cross-border acquisition in the domestic medical beauty industry, aiming to enhance its product portfolio and market presence [5][9]. - The ongoing dispute between 江苏吴中 and 爱美客 over the distribution rights of 艾塑菲 highlights the competitive landscape and the challenges of dependency on agency models in the medical beauty sector [19][20]. Group 4: R&D and Innovation - 爱美客 has increased its R&D investment to 1.57 billion yuan, representing 12.05% of its revenue, indicating a focus on enhancing its competitive edge through innovation [8]. - The company holds 182 valid patents, including 53 invention patents, showcasing its commitment to developing proprietary technologies [8].

Company Overview - Yangmei Biotechnology (Chengdu) Co., Ltd. is a medical health enterprise established in 2016, focusing on the research, production, and commercialization of regenerative medical devices and special medical foods [3] - The company specializes in the development, transformation, and application of regenerative medical materials, as well as the research and development of specific full-nutrition formula foods [3] - Yangmei Biotechnology has accumulated key technologies in the fields of polymer materials and regenerative biomaterials, including research, modification, preparation, and the development of microspheres [3] Product Lines - The company has a strong product portfolio that includes two main product lines: regenerative medical material injectables and medical dressings and patches [3] - As of May 5, 2025, the company has 13 candidate products for regenerative medical material injectables, including core product XH301 and candidate product XH321 for treating female stress urinary incontinence, with two products already in the registration review stage [4] - In the medical dressings and patches product line, seven products have obtained second-class medical device registration approval, and one candidate product XH322 for breast reconstruction post-breast cancer surgery is in the preclinical stage [4] - The special medical food product line includes two products approved by the National Medical Products Administration and seven candidate products under development [4] Financial Performance - The company's revenue for 2023 and 2024 is projected to be RMB 12.88 million and RMB 14.52 million, respectively [5] - The total loss for the same periods is expected to be RMB 63.50 million and RMB 69.38 million, indicating ongoing financial challenges [5] - Gross profit for 2023 is RMB 1.47 million, which decreases to RMB 0.38 million in 2024, reflecting a decline in profitability [5]

深创投新材料基金领投。 本文为IPO早知道原创 作者｜C叔 微信公众号｜ipozaozhidao 诺一迈尔同步推进国际化布局，2024年，公司创新医疗器械Neosprout鼻腔止血海绵产品相继获得 CE MDR和FDA批准上市；此外，多款创新医疗器械正在同步进行海外注册和市场推广。 诺一迈尔已经设立苏州、潍坊、太仓、上海四个研发生产基地，北京医学中心和德国弗莱堡海外实验 室，形成了"4+1+1"的研发创新架构。公司已建成洁净厂房总面积超过3万平方米，可快速响应下游 需求，为临床医生和患者提供了可靠的解决方案和产品，贡献于当地经济发展，带动就业。 诺一迈尔表示，非常感谢新材料基金对诺一迈尔的支持，及全体老股东对公司的信任。诺一迈尔已迈 入加速商业化落地的关键阶段，公司将继续秉持"创新+国际化"的发展战略，提供更丰富的产品组合 造福全球患者。 本文由公众号IPO早知道（ID：ipozaozhidao）原创撰写，如需转载请联系C叔↓↓↓ 据IPO早知道消息，近日，诺一迈尔（苏州）医学科技有限公司（下称"诺一迈尔"）宣布完成近3亿 元C轮融资，由深创投制造业转型升级新材料基金领投，部分老股东及管理层跟投，凯乘资本担任 ...