1月8日，爱美客公告，其经销的注射用A型肉毒毒素产品获得国家药品监督管理局核准签发的《药品注 册证书》。 智通财经记者 | 李科文 智通财经编辑 | 谢欣 这是爱美客首款注射用A型肉毒毒素产品，也是国内第七款。1月9日，智通财经记者联系爱美客，截至 发稿未获回复。 爱美客肉毒素布局起于2021年。 2021年，爱美客以8.56亿元收购韩国医美公司Huons BioPharma 25.42%的股权。 Huons BioPharma原是韩国上市公司Huons Global Co., Ltd.的肉毒毒素等生物制品业务部门。Huons Global分拆肉毒毒素等生物制品业务部门并成立了如今的Huons BioPharma。 2022年5月，爱美客以研发注册方式引进Huons BioPharma生产的注射用A型肉毒毒素产品，并在约定经 销区域内作为Huons BioPharma指定的唯一且排他的进口商、经销商。 肉毒素能否接力成为爱美客的第三增长点，目前仍存在较大不确定性。 与此前在再生医美赛道中抢占第一梯队不同，爱美客此次推出的产品，已是国内第七款同类产品。 在此之前，我国合规上市的肉毒素产品已有6款，分别包括美国艾 ...

在产品优势方面，崇山生物董事长张智武表示，胶媛天使的高标准主要体现在三个经过重新定义的 核心维度。首先，在成分浓度上，产品采用了高达45mg/ml的医用胶原蛋白浓度，奠定了强效支撑的基 础。其次，在材料来源上，精选牛跟腱提取胶原蛋白，确保了原料的高纯净度与结构完整性。最后，在 应用技术上，该产品可实现皮下深层的精准植入，为肌肤提供更深层的网络支撑。 张智武还介绍道，在研发过程中，团队攻克了多项行业技术难点。其中，浓度的科学遴选至关重 要。多年研究证实，并非浓度越高越好，盲目提高浓度可能带来钙化风险。崇山生物通过严谨实验，将 45mg/ml确立为最佳平衡点，既能优化胶原网络形成，又保障了安全性。另一大难点在于活性保持，公 司采用了全套活性胶原生产技术，通过全程精细化管控，最大限度地保留了胶原蛋白的生物活性与完整 结构，从而确保了产品效果的长期性与稳定性。 此次媛颂集团与崇山生物的战略合作，标志着临床机构与研发企业协同模式的深度升级。面对竞争 激烈的胶原蛋白赛道，媛颂集团CEO马伟伟表示，不只是引入一款新产品，更是以娇媛天使的功能效果 为基础，结合抗衰医学、自然美学、材料学，打造一套全新的诊疗方案。" 1月2日， ...

1月2日，媛颂集团与崇山生物正式达成战略合作，全球首款源自牛跟腱的胶原蛋白产品将在媛颂全国直 营体系率先首发。据悉，该款"娇媛天使"产品于月前（12月10日）刚刚获得国家药监局三类医疗器械注 册审批。 截至目前，国内已获第三类医疗器械证书的胶原蛋白产品增至15款。面对日渐激烈的市场竞争，关 于"娇媛天使"的市场判断，媛颂集团CEO马伟伟在发布会上表示，双方将产品与应用的技术优势相结 合，将全面改写胶原蛋白在市场的应用，推动胶原领域从"体积增容"迈入"营养紧致"的全新阶段。 "业内此前使用胶原蛋白产品，多聚焦于填充饱满的即时效果。随着娇媛天使的上市，媛颂希望推动胶 原领域从"体积增容"迈入"营养紧致"的全新阶段。我们判断，未来胶原蛋白市场的应用将被全面改写， 营养紧致将成为行业主流趋势。"马伟伟预测。 截止目前，媛颂集团在医美领域打造了多个爆款新材料和新品，例如华东医药"伊妍仕"、爱美客"濡白 天使"、四环医药"微笑童颜"等高标品系列，成为引领市场话语权的机构。市场分析预测，凭借产品技 术优势和媛颂体系的推广实力，娇媛天使有望在短期内抢占相当市场份额，或将成为2026年医美市场的 一匹黑马。 在产品优势方面，崇 ...

另一家"童颜针"生产商普丽妍也于上个月将40余家新氧青春诊所列为"非官方合作医疗机构"；今年6 月，圣博玛发表公开声明，称新氧销售的"童颜针"产品"艾维岚"为非合规授权渠道，并指该诊所的医生 未接受厂家培训指导，难以保障消费者健康安全。 针对多家供应商"围堵"，12月12日，新氧旗下"新氧青春诊所"在公众号发布声明，直指上游厂商固化高 价体系，弱化医疗机构的自主定价权。 来源：第一财经 近日，医美公司新氧的低价策略激化了与上游厂商的矛盾，并已遭到多家供应商抵制。12月15日美股收 盘，新氧（SY.US）股价当天大跌近6%，近5个交易日股价累计下跌约10%。 引发最新矛盾的是12月11日"童颜针"生产商斐缦生物的一纸公开声明，该公司称，已自10月1日起已经 停止向新氧集团及其下属新氧青春诊所等供应"弗缦"产品（一种胶原蛋白填充剂）。声明还强调，"以 上机构若继续大量销售我公司'弗缦'产品，则涉嫌产品从不合规渠道获得，或为假冒伪劣产品。" 第一财经记者梳理公开信息发现，目前已经在国内获批上市的"童颜针"产品已有约11款，包括圣博玛生 物的"艾维岚"、爱美客的"濡白天使"、高德美的"塑颜萃"、普丽妍的同名产品以及四 ...

Core Viewpoint - The article discusses the recent conflicts between medical beauty company New Oxygen and its upstream suppliers due to New Oxygen's low pricing strategy, which has led to a significant drop in its stock price and supplier resistance [3][6]. Summary by Sections Supplier Conflicts - New Oxygen's low pricing strategy has intensified conflicts with suppliers, leading to several suppliers, including Faiman Bio, ceasing to supply products to New Oxygen since October 1 [3][4]. - Suppliers claim that New Oxygen's pricing disrupts the market's pricing system, resulting in a "supply cut" from multiple manufacturers [5][6]. Pricing Strategy - New Oxygen offers its own brand of "童颜针" (youthful needle) products at significantly lower prices compared to the market, with prices as low as 999 yuan for the basic version and 2999 yuan for the upgraded version [5]. - The article highlights that while major brands price their products above 10,000 yuan, New Oxygen's pricing strategy allows it to sell similar products for much lower prices, attracting a large customer base [5][6]. Business Model - New Oxygen's business model is characterized by using low prices as a customer acquisition strategy, collaborating with upstream manufacturers to eliminate middlemen and reduce costs [6][7]. - The company reportedly utilizes lower-cost OEM production methods, allowing it to maintain high profit margins despite lower retail prices [6][7]. Market Impact - The ongoing conflict between New Oxygen and its suppliers is expected to have limited long-term effects on the overall market, with the public disputes serving to clarify positions among the involved parties [8].

"童颜针"的主要成分为"聚左旋乳酸（PLLA）填充剂"，这种产品被宣传为可以通过注射刺激皮肤胶原 蛋白再生，实现面部轮廓塑形、皱纹改善的中长效（2-3年）抗衰医美产品。 近日，医美公司新氧的低价策略激化了与上游厂商的矛盾，并已遭到多家供应商抵制。12月15日美股收 盘，新氧（SY.US）股价当天大跌近6%，近5个交易日股价累计下跌约10%。 引发最新矛盾的是12月11日"童颜针"生产商斐缦生物的一纸公开声明，该公司称，已自10月1日起已经 停止向新氧集团及其下属新氧青春诊所等供应"弗缦"产品（一种胶原蛋白填充剂）。声明还强调，"以 上机构若继续大量销售我公司'弗缦'产品，则涉嫌产品从不合规渠道获得，或为假冒伪劣产品。" 另一家"童颜针"生产商普丽妍也于上个月将40余家新氧青春诊所列为"非官方合作医疗机构"；今年6 月，圣博玛发表公开声明，称新氧销售的"童颜针"产品"艾维岚"为非合规授权渠道，并指该诊所的医生 未接受厂家培训指导，难以保障消费者健康安全。 针对多家供应商"围堵"，12月12日，新氧旗下"新氧青春诊所"在公众号发布声明，直指上游厂商固化高 价体系，弱化医疗机构的自主定价权。 不过，12月16日，第 ...

Core Viewpoint - The ongoing conflict between the medical beauty platform company New Oxygen and its suppliers highlights a significant pricing power struggle in the industry, particularly regarding the pricing of the "童颜针" (youthful needle) product, which New Oxygen has drastically reduced from market prices to attract consumers [2][3][4]. Group 1: Pricing Conflict - New Oxygen has been publicly accused by suppliers, including Purity and Saint Boma, of sourcing products through unauthorized channels and has faced scrutiny over the legitimacy of its clinics [3][25]. - The core of the conflict revolves around New Oxygen's aggressive pricing strategy, which has seen the price of the "童颜针" drop from approximately 10,000 yuan to 2,999 yuan, representing a nearly 70% reduction [4][26]. - New Oxygen claims that its low pricing strategy is based on "value return," achieved through large-scale procurement and reduced marketing costs [4][26]. Group 2: Financial Performance - In the first three quarters of 2024, New Oxygen reported total revenue of 1.063 billion yuan, a year-on-year decline of 3.36%, with a net loss of 133 million yuan, a shift from a profit of 20.78 million yuan in the same period last year [14][36]. - The company's gross profit margin for the same period was 49.21%, down 13.02 percentage points year-on-year, primarily due to lower margins from offline services compared to traditional information services [16][38]. - The rapid expansion of offline beauty treatment services has led to a significant increase in revenue, with a 385.05% year-on-year growth to 427 million yuan, now accounting for 40.16% of total revenue [15][37]. Group 3: Operational Challenges - New Oxygen's shift to a heavy asset model has increased operational costs, with total operating costs reaching 540 million yuan, representing 50.8% of revenue, significantly higher than the traditional platform model [16][39]. - The company faces challenges in maintaining service quality due to a lack of a stable and experienced medical team, which is crucial for the quality of medical beauty services [39]. - Regulatory risks have increased as offline medical practices are subject to stringent oversight from multiple regulatory bodies, raising concerns about compliance and potential public relations crises [39].

Core Viewpoint - The price war surrounding "童颜针" (youthful needle) is not only challenging the pricing system of the medical beauty industry but also testing the transformation path of the company, 新氧 (Xinyang) [1] Group 1: Price War and Market Dynamics - 新氧 has significantly reduced the price of "童颜针" from tens of thousands to 2999 yuan, aiming to gain pricing autonomy through its "奇迹童颜" series and the new "塑缇妍" product [1][8] - The conflict escalated as the manufacturer, 普丽妍, publicly named 新氧's clinics as "non-official partners," questioning their product sources and doctor qualifications [3][4] - The price reduction strategy has raised concerns about the sustainability of the medical beauty industry's profit distribution and the traditional agency model [4][5] Group 2: Transformation Challenges - 新氧's transition from a platform to a direct participant in the industry has led to conflicts with previously partnered medical institutions, resulting in a significant decline in its platform service revenue [11][12] - The company's aggressive expansion into self-operated clinics has resulted in increased costs and operational challenges, with a reported net loss of 64.3 million yuan in the third quarter [12][13] - Despite the challenges, the self-operated business is seen as a key driver for future growth, with a 304.6% year-on-year increase in medical treatment service revenue [12] Group 3: Pricing Strategy and Cost Structure - The drastic price reduction of 70% for "童颜针" is not solely based on cost but is a strategic market move to disrupt the high-price perception in the industry [5][6] - 新氧's lower pricing is attributed to its ability to bypass traditional distribution layers and its strategy of low-margin, high-volume sales [6][7] - The company claims that its pricing reflects a trend towards "value return" in medical beauty consumption, with a 27.1% increase in consumer visits but a 30.9% decrease in average spending [7] Group 4: Regulatory and Compliance Issues - 新氧 has faced multiple regulatory challenges, including fines for non-compliance with national standards and advertising laws [13][14] - The company acknowledges the importance of addressing consumer complaints and emphasizes that its low-cost model does not compromise regulatory compliance [14]

一场围绕童颜针的价格战，拷打的不止是医美行业的定价体系，更是新氧的转型之路。近日，童颜针厂 商普丽妍公开点名新氧旗下数十家诊所为"非官方合作机构"，质疑其产品来源与医生资质，而新氧则强 硬回应，强调其产品渠道合规、全程可溯。这已是新氧今年第二次与上游厂商公开对峙，今年以来，新 氧以"奇迹童颜"系列将"童颜针"价格从万元级一路拉低至2999元，并进一步通过与西宏生物合作推出定 制款"塑缇妍"（奇迹童颜3.0），以差异化的规格与创行业新低的定价，试图完全掌握定价自主权。 激烈价格战的背后，是新氧转型的迫切。面对线上流量红利消退，这家曾经的医美垂直平台正试图通过 自建"青春诊所"完成转型。然而，重资产扩张带来的成本压力、与传统合作生态的冲突以及服务质量与 合规性的质疑，共同构成了其转型之路上的多重考验。胜负的关键，或许不在于价格能否更低，而在于 其能否在颠覆之后，构建一个真正健康、安全且可持续的新模式。 "厂商没办法出货了" 当一份列有79家"非官方合作医疗机构"的名单公开，持续半年的"童颜针定价权之争"再次升级。 近期，童颜针厂商普丽妍公开发布"非官方合作医疗机构"名单，直指46家新氧青春诊所在内的70余家医 疗 ...

Core Viewpoint - The ongoing price war surrounding "童颜针" (youthful needle) is not only challenging the pricing system of the medical beauty industry but also represents a critical transformation path for the company, 新氧 (So-Young) [2][14]. Group 1: Price War and Market Dynamics - 新氧 has significantly reduced the price of "童颜针" from over 10,000 RMB to 2,999 RMB, aiming to gain control over pricing autonomy [2][10]. - The company faces accusations from suppliers like 普丽妍, which has labeled many of 新氧's clinics as "non-official partners," questioning the legitimacy of their product sources and medical qualifications [3][4]. - The price reduction strategy is seen as a challenge to the traditional profit distribution model in the medical beauty industry, where high prices were previously justified by perceived quality [6][7]. Group 2: Transformation Challenges - 新氧 is transitioning from a platform-based model to a direct participant in the medical beauty industry by establishing its own clinics, which has led to conflicts with previously partnered medical institutions [14][15]. - The company's revenue from information and reservation services has declined significantly, with a 34.5% year-on-year drop in the third quarter [14]. - Despite the aggressive expansion into self-operated clinics, 新氧 has reported continuous losses, with a net loss of 64.8 million RMB in the third quarter of 2025 [15][16]. Group 3: Financial Performance and Cost Structure - 新氧's aesthetic treatment services revenue surged by 304.6% year-on-year to 1.84 billion RMB in the third quarter, becoming the largest revenue source [17]. - The gross profit margin for 新氧's medical aesthetic services was reported at only 24.25% in the second quarter of 2025, indicating a significant deviation from industry standards [8][9]. - The company is focusing on cost optimization through strategies like scale procurement and supply chain integration to improve profitability [17]. Group 4: Regulatory and Compliance Issues - 新氧 has faced multiple complaints regarding service quality and compliance, with 876 complaints recorded on consumer platforms, including issues related to false advertising and operational violations [17][19]. - The company has been penalized for non-compliance with national standards, highlighting the regulatory risks associated with its rapid expansion [17][18]. - 新氧 emphasizes that its low pricing strategy does not compromise regulatory compliance and is committed to addressing consumer feedback seriously [19].