智通财经APP讯，歌礼制药-B(01672)发布截至2025年6月30日止6个月的中期业绩，该集团取得收入总额 人民币1.04亿元(单位下同)，同比增加111.4%;研发成本1.47亿元，同比增加10.9%;公司权益股东应占亏 损8795.1万元，同比减少32.5%;每股亏损9.14分。 于报告期内及直至本公告日期，本集团在代谢性疾病管线、免疫性疾病管线及拓展性适应症产品管线方 面取得重大进展：ASC30每日一次口服片治疗肥胖症：在美国Ib期研究中，经28天治疗后，经安慰剂校 准后的相对基线的平均体重下降高达6.5%，证明其有望成为治疗肥胖症的同类最佳候选药物。 本集团开展美国IIa 期研究并于仅一月余内迅速完成125名受试者入组;ASC30每月一次或更低频次皮下 注射治疗肥胖症：在美国Ib期研究中，单次皮下注射后在肥胖症患者中表现出36天半衰期，支持每月一 次或更低频次给药。本集团开展美国IIa期临床研究并完成首批受试者给药;ASC47每月一次或更低频次 皮下注射用于不减肌的肥胖症治疗：在肥胖症患者中显示出40天的半衰期。本集团开展ASC47与司美格 鲁肽联合用药的美国研究并完成所有28名肥胖症受试者入组; ...

Core Viewpoint - Acne is a common issue faced by adolescents, particularly during the summer months when high temperatures and humidity can exacerbate the condition. Experts suggest that while mild acne can often resolve with daily care, moderate to severe cases should be treated promptly to prevent long-term skin damage and psychological effects [1][2]. Group 1: Causes and Mechanisms - Acne is a chronic inflammatory skin disease affecting the pilosebaceous unit, primarily seen in adolescents due to increased androgen levels and sebum production [1]. - Factors contributing to acne include excessive keratinization of hair follicles, bacterial infections, hormonal imbalances, immune factors, psychological stress, chemical irritants, and genetic predisposition [1]. - Lifestyle factors such as smoking, alcohol consumption, medication use, and inappropriate cosmetic choices can also trigger acne outbreaks [1]. Group 2: Treatment Recommendations - For mild acne, daily care such as using gentle cleansers, avoiding irritating skincare products, not squeezing pimples, and maintaining a balanced diet and regular sleep schedule is recommended [2]. - Moderate to severe acne, if untreated, can lead to scarring and impact mental health and social interactions, necessitating professional medical intervention [2]. - Acne typically improves with age as hormone levels stabilize, but moderate to severe cases may require targeted treatment strategies as self-resolution is less likely [2].