Core Viewpoint - The demand for anti-wrinkle and firming skincare products in China is rapidly increasing, with the retail market expected to reach 64.027 billion yuan in 2024, reflecting a year-on-year growth of 21.50%. Consumers are shifting from a focus on single efficacy to multi-functional products that offer benefits such as anti-free radical and skin barrier repair, marking a transition from "ingredient stacking" to "mechanism-driven" innovations in the industry [1][16]. Overview - Anti-wrinkle and firming skincare products aim to improve skin wrinkles and enhance elasticity and firmness. Their mechanisms include supplementing or stimulating the synthesis of collagen and elastin, improving skin moisture content and barrier function, inhibiting the activity of enzymes that damage skin structure, and providing antioxidant and anti-inflammatory effects to mitigate skin aging [2][5]. Development History - The domestic skincare market was in its infancy before the 1990s, with limited demand for anti-wrinkle products. The introduction of these products began in the 1990s, primarily through imported brands. Post-2010, the market experienced rapid growth due to increased consumer awareness and economic development, leading to the rise of domestic brands that began to compete effectively with multinational companies [5][6]. Market Policies - The Chinese government has implemented a series of policies to enhance the development of the cosmetics industry, including regulations on production quality management, adverse reaction monitoring, and electronic registration. These policies aim to promote standardization and high-quality development in the anti-wrinkle and firming skincare sector [10][11]. Industry Chain - The upstream of the anti-wrinkle and firming skincare industry includes suppliers of active ingredients like hyaluronic acid and peptides, as well as suppliers of moisturizing agents and packaging materials. The downstream consists of various sales channels, including department stores, supermarkets, specialty stores, beauty salons, and e-commerce platforms [13][15]. Consumer Insights - The consumer base for anti-wrinkle and firming products is predominantly female, accounting for over 85%, while the male anti-aging market is growing at a rate of 30%. The core consumer group is aged 26-35, focusing on preventive anti-aging and multifunctional products. Safety is the primary concern for 94.93% of consumers, significantly impacting repurchase rates and brand trust [15][16]. Competitive Landscape - The market is becoming increasingly competitive, with international brands like Estée Lauder, L'Oréal, Procter & Gamble, and Shiseido dominating the mid-to-high-end segments. Domestic brands such as Proya, Chando, and Marubi are gaining significant market share due to their understanding of local consumer preferences and competitive pricing [19][22]. Future Trends - The future demand for anti-aging products will focus on multi-functional benefits, including anti-wrinkle, anti-free radical, and skin barrier repair. There is a growing emphasis on emotional value, with over half of female consumers willing to purchase products that offer additional emotional satisfaction, prompting brands to enhance their offerings through packaging design and brand storytelling [27][29].

Core Viewpoint - The article highlights the rising popularity of the American version of ultrasound knife technology in the anti-aging sector, emphasizing its effectiveness and precision in achieving facial lifting and tightening results [1][3]. Group 1: Technology and Effectiveness - The American ultrasound knife is recognized for its strong lifting effect, improving skin elasticity and reducing wrinkles, leading to clearer facial contours [3]. - This technology has received FDA certification, ensuring its safety and effectiveness [3]. - It utilizes high-intensity focused ultrasound to target the SMAS layer, tightening loose muscle tissue and providing long-lasting lifting effects [3]. Group 2: Precision and Customization - The ultrasound knife's precision is enhanced by real-time imaging technology, allowing doctors to observe skin structure and adjust treatment depth and energy according to individual skin conditions [3]. - The Ulthera® specialized probe can be customized for different depths (1.5mm, 3.0mm, 4.5mm) to treat various skin layers, achieving natural and effective lifting and tightening results [3]. Group 3: VelyB Hospital's Role - VelyB Hospital is recognized for its strong reputation in the medical aesthetics field and has introduced advanced technologies like the American ultrasound knife as part of its anti-aging strategy [6]. - The hospital boasts a skilled medical team trained in the operation of the ultrasound knife, capable of creating personalized treatment plans based on individual facial characteristics and needs [6]. - Various treatment options are available at VelyB Hospital, including different shot counts (100, 300, 600), catering to diverse client needs from mild skin laxity to significant facial sagging [6].

Core Insights - The understanding of aging is evolving from a linear perspective to a dynamic interplay of genetics, lifestyle, and environmental exposure, with significant individual differences in organ age among peers [1] - The market is shifting from vague concepts of overall youthfulness to targeted organ-specific care, addressing core pain points such as liver detoxification, collagen loss in skin, and testosterone decline in men [2] Group 1: Company Innovations - LAIFE, a Boston-based life sciences AI formulation brand, is leveraging AI technology to decode the molecular mechanisms of organ aging, transitioning from "experience medicine" to "computational medicine" [2][3] - The RevOrgan AI formulation platform developed by LAIFE utilizes deep learning algorithms and organ aging models to create dynamic formulations, significantly reducing R&D time and enhancing product efficacy and stability [3][5] Group 2: Product Development - LAIFE has established a product matrix that includes various targeted formulations such as LAIFE "乐净肺" for lung health, LAIFE "乐轻肝" for liver support, and LAIFE "红宝瓶II" for ovarian health, addressing aging from multiple dimensions [5] - The AI system employed by LAIFE can dynamically simulate metabolic responses in organs, allowing for precise selection and optimization of ingredients through high-performance computing [5] Group 3: Research and Development - LAIFE's research foundation is supported by its parent company, RegenerativeBio, which integrates AI with biotechnology to enhance product precision and effectiveness [7] - The team at RegenerativeBio includes top scientists from prestigious institutions, ensuring rigorous testing and validation of LAIFE's products to meet international standards [7] Group 4: Future of Aging Science - LAIFE is pioneering a new paradigm in aging science, transforming aging from an inevitable fate into a decodable and potentially reversible process, enabled by advanced AI computational capabilities [9] - The company is actively promoting the integration of AI in aging research, hosting conferences and supporting academic initiatives to advance the field [7][9]

Core Viewpoint - The article emphasizes the transition of "skin management" from traditional beauty care to a new stage of precise anti-aging supported by material science and bioengineering, focusing on collagen as a key material in skin health and tissue regeneration [1]. Group 1: Event Information - The event is scheduled for May 23, 2025, from 14:00 to 16:30 at Langcheng Building, Beijing, and is limited to on-site communication without online streaming [2]. - The event is organized by the Baidachu Plastic Surgery Medical Concept Verification Center, targeting researchers, corporate representatives, and investors involved in skin management, biomaterials, and medical aesthetics product development [2]. - Participation is free but subject to a limited review process [2]. Group 2: Key Speakers and Topics - The opening introduction will be conducted by Yao Guijin, the Deputy General Manager of Baidachu Plastic Surgery Group and head of the verification center [3]. - Zhang Guifeng, Deputy Director of the Biological Technology Working Committee of the China Anti-Aging Promotion Association, will present on the scientific basis and innovative pathways of collagen in skin management, discussing the synergistic effects of collagen, elastin, and peptides [5]. - The event will include a free discussion segment focusing on various topics, including the application scenarios of collagen in skin management and the design logic of cross-border products from skincare to medical materials [6].