Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company has demonstrated steady profit growth, with multi-channel operations empowering long-term development [1] - The company's revenue for H1 2025 was 11.722 billion yuan, a slight decrease of 0.34% year-on-year, while net profit attributable to shareholders was 880 million yuan, an increase of 10.32% [7] - The company is focusing on optimizing its store network, with a total of 14,701 stores as of H1 2025, including 4,020 franchise stores [7] - The online and offline collaboration has been enhanced, with internet sales reaching 1.355 billion yuan in H1 2025, contributing significantly to overall revenue [7] - The profit forecast for 2025-2027 has been slightly adjusted, with net profit attributable to shareholders expected to be 1.768 billion yuan in 2025, 1.982 billion yuan in 2026, and 2.228 billion yuan in 2027 [7] Financial Summary - Total revenue is projected to grow from 24.062 billion yuan in 2024 to 30.881 billion yuan in 2027, with a compound annual growth rate (CAGR) of approximately 7.69% [1][8] - The net profit attributable to shareholders is expected to increase from 1.529 billion yuan in 2024 to 2.228 billion yuan in 2027, reflecting a CAGR of approximately 12.37% [1][8] - The earnings per share (EPS) is forecasted to rise from 1.26 yuan in 2024 to 1.84 yuan in 2027 [1][8] - The company's price-to-earnings (P/E) ratio is projected to decrease from 19.37 in 2024 to 13.29 in 2027, indicating potential valuation improvement [1][8]

Meeting Overview - The company is holding its second extraordinary general meeting of shareholders in 2025 on September 15 [2] - The meeting aims to ensure the normal order and efficiency of discussions while protecting the legal rights of all shareholders [3] Agenda Items - The meeting will discuss ten proposals, including five ordinary and five special resolutions [5] - Key proposals include the stock option incentive plan for 2025, employee stock ownership plan, and amendments to the company's articles of association [6][9] Stock Option Incentive Plan - The company has proposed a stock option incentive plan for 2025 to attract and retain talent, aligning the interests of shareholders, the company, and employees [10][11] - The plan includes a management assessment method to ensure its effective implementation [12] Employee Stock Ownership Plan - The company is also proposing an employee stock ownership plan for 2025 to enhance employee engagement and company competitiveness [17][18] - The plan aims to create a mechanism for shared risks and benefits among employees and shareholders [17] Governance Changes - The company plans to cancel its supervisory board, transferring its responsibilities to the audit committee of the board of directors [8] - Amendments to the company's articles of association will be made to reflect changes in governance structure and improve operational efficiency [8][9] Risk Management - The company intends to purchase liability insurance for directors and senior management to mitigate governance and operational risks [10]

Summary of the Conference Call on the Pharmaceutical Industry Industry Overview - The pharmaceutical industry experienced a profit decline in 2019 due to centralized procurement policies, but demand growth during the pandemic provided some relief. By the first half of 2025, segments such as innovative drugs, pharmaceutical commerce, and CXO showed positive growth, although overall profit levels continued to decline [1][2]. Key Insights and Arguments - **Centralized Procurement Impact**: The centralized procurement of medical consumables began in 2020, leading to negative revenue growth for two consecutive quarters by Q4 2023. However, Q1 2024 saw a return to positive revenue growth, indicating a stabilization in high-value consumables [3][4]. - **Sector Performance**: The chemical preparations sector saw significant revenue declines in Q3 and Q4 of 2023, directly linked to centralized procurement policies. The medical consumables sector has faced revenue and profit pressures since 2022, with in vitro diagnostics (IVD) expected to face challenges starting Q4 2024 [5][6]. - **Future Outlook**: The worst period for the pharmaceutical industry is believed to be over, with price issues being resolved. The price levels are relatively low compared to international markets, and a return to positive growth is anticipated in Q2 2025, potentially leading to an overall positive growth for the year [6][7]. Segment-Specific Insights - **CXO Sector**: The CXO sector is divided into demand-driven and supply-driven enterprises. The latter has benefited from the recovery of overseas markets, while domestic demand-driven companies are beginning to show signs of recovery, as evidenced by the performance of companies like Tigermed and Northstar [7][8]. - **IVD Sector**: The IVD sector is under significant pressure due to policy impacts, with a notable 20% decline in Roche's domestic luminescence business. The overall industry growth rate is approximately -15% [12][13]. - **Medical Equipment**: The medical equipment sector has faced continuous declines since Q4 2023, but signs of recovery were noted in the first half of 2025, with companies like United Imaging and Mindray showing varying degrees of recovery [17][18]. Additional Important Points - **High-Value Consumables**: The high-value consumables sector has undergone multiple rounds of centralized procurement, leading to stable or improved performance for many companies. The gross margin levels for high-value consumables have reached a bottom, with certain products like artificial crystals beginning to see the effects of procurement policies [19][20]. - **Internationalization of Domestic Companies**: Domestic high-value consumables companies are enhancing their international capabilities, with significant clinical data published and FDA certifications obtained for products aimed at the U.S. market [23]. - **Market Competition**: The competition in the luminescence industry is intense, particularly among companies outside the top three, which are resorting to price cuts to gain market share, resulting in significant declines in gross margins [13][14]. This summary encapsulates the key points discussed in the conference call regarding the pharmaceutical industry, highlighting the challenges and opportunities within various segments.

Core Viewpoint - Liu Pharmaceutical Group reported a decline in revenue and net profit for the first half of 2025, primarily due to stricter control of drug usage ratios in medical institutions and the impact of centralized procurement policies [2] Financial Performance - For the first half of 2025, Liu Pharmaceutical Group achieved revenue of 10.301 billion yuan, a year-on-year decrease of 3.21% - The net profit attributable to shareholders was 430 million yuan, down 7.52% compared to the previous year [2] Business Challenges - The decline in performance is attributed to the significant impact of medical insurance cost control and the tightening of drug usage ratios in Guangxi's medical institutions, leading to a temporary decrease in medication volume [2] - The expansion of centralized procurement has also affected the gross margins of related products, while sales of non-centralized procurement products have been impacted [2] Strategic Initiatives - The company is focusing on optimizing its product structure, reducing costs, and enhancing efficiency, alongside the development of retail, industrial, and innovative businesses to gradually mitigate the impact of industry policies and restore stable growth [2] - Liu Pharmaceutical Group has implemented measures to control accounts receivable and improve cash flow, with a 78.07% increase in net cash flow from operating activities compared to the previous year [2][3] AI and Technology Integration - The company is leveraging AI technology in various areas, including the development of an intelligent warehouse system to optimize logistics operations and enhance supply chain efficiency [3][4] - AI applications are being integrated into hospital settings for patient management and diagnosis, with ongoing collaborations with hospitals to implement intelligent modules [4] - In the retail sector, Liu Pharmaceutical Group has introduced an AI pharmacist assistant to provide comprehensive health management services for patients [4][5] Innovation and R&D - Liu Pharmaceutical Group has invested in the overseas innovative drug company Suninflam Ltd., focusing on the development of monoclonal antibody drugs targeting key factors in inflammatory responses [5][6] - The project has successfully completed the efficacy evaluation and is currently in the process of conducting Phase I clinical trials for epilepsy in the United States, with promising preliminary results [6]

证券日报网讯 9月4日晚间，第一医药发布公告称，公司2025年第二次临时股东会于2025年9月4日召 开，审议通过了《关于续聘内部控制审计会计师事务所的议案》等。 （文章来源：证券日报） ...

Core Viewpoint - Liu Pharmaceutical Group reported a decline in revenue and net profit for the first half of 2025, primarily due to stricter control on drug usage in public hospitals and the impact of centralized procurement policies [1][2] Financial Performance - For the first half of 2025, Liu Pharmaceutical Group achieved revenue of 10.301 billion yuan, a year-on-year decrease of 3.21% - The net profit attributable to shareholders was 430 million yuan, down 7.52% compared to the previous year [1] Business Challenges - The decline in performance is attributed to the significant impact of medical insurance cost control and stricter drug usage ratios in Guangxi's medical institutions - The company has also reduced sales to certain hospitals with long payment cycles, leading to decreased wholesale business sales and profit margins [1][2] Cash Flow and Receivables Management - The scale of accounts receivable decreased year-on-year, with a net cash flow from operating activities increasing by 78.07% compared to the same period last year - The company is focusing on improving cash flow by enhancing accounts receivable management and reducing risks associated with long payment cycles [2] AI and Technology Integration - Liu Pharmaceutical Group is implementing AI technologies in various areas, including supply chain management and hospital services - The company has developed an intelligent warehouse system and is applying AI algorithms to optimize logistics and operational efficiency [2][3] Healthcare Services Innovation - The company is launching AI-assisted services in hospitals, including intelligent triage and patient management - A dual-service model is being developed to provide comprehensive health management for outpatients, utilizing an AI pharmacist assistant [3] Investment in Innovation - Liu Pharmaceutical Group has invested in the overseas innovative drug company Suninflam Ltd., focusing on developing monoclonal antibody drugs targeting inflammation and neurodegenerative diseases - The first product, SIF001, has entered clinical trials in the U.S. and has shown promising efficacy in initial studies [4][5]

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上海市金茂律师事务所 关于上海第一医药股份有限公司 法律意见书 致：上海第一医药股份有限公司 （以下简称"《证券法》"）、 《上市公司股东会规则》（以下简称"《股东会规则》"）、《上海证券交易所 上市公司自律监管指引第 1 号——规范运作（2025 年 5 月修订）》（以下简称 "《自律监管指引 1 号》"）等有关法律、法规和规范性文件以及《上海第一医 药股份有限公司章程》（以下简称"《公司章程》"）而出具。 为出具本法律意见书，本所审查了公司本次股东会的有关文件和材料。本所 得到公司如下保证，即其已提供了本所认为出具本法律意见书所必需的材料，所 提供的原始材料、副本、复印件等材料、口头证言均符合真实、准确、完整的要 求，有关副本、复印件等材料与原始材料一致。 为出具本法律意见书，本所律师按照律师行业公认的业务标准、道德规范和 勤勉尽责精神，就本次股东会的召集、召开程序，出席会议人员的资格，会议议 案，以及会议的表决程序、表决结果的合法有效性发表意见如下： （正文） （引言） 上海第一医药股份有限公司（以下简称"公司"）2025 年第二次临时股东 会（以下简称"本次股东会"）于 2025 年 9 月 4 日在 ...

Market Overview - The pharmaceutical commercial sector experienced a slight decline of 0.07% on September 4, with Saily Medical leading the drop [1] - The Shanghai Composite Index closed at 3765.88, down 1.25%, while the Shenzhen Component Index closed at 12118.7, down 2.83% [1] Stock Performance - Notable gainers in the pharmaceutical commercial sector included: - HeFu China (603122) with a closing price of 6.66, up 1.99% [1] - JianZhiJia (605266) at 21.56, up 1.84% [1] - YiXinTang (002727) at 14.98, up 1.70% [1] - Saily Medical (603716) was the biggest loser, closing at 29.00, down 2.26% [2] Trading Volume and Value - The trading volume and value for selected stocks were as follows: - YiXinTang (002727) had a trading volume of 144,800 hands and a transaction value of 216 million [1] - Saily Medical (603716) recorded a trading volume of 256,800 hands with a transaction value of 759 million [2] Capital Flow - The pharmaceutical commercial sector saw a net outflow of 169 million from institutional investors, while retail investors had a net inflow of 210 million [2] - Key stocks with significant capital flow included: - BaiYang Pharmaceutical (301015) with a net inflow of 15.09 million from institutional investors [3] - LaoBaiXing (603883) with a net inflow of 13.41 million from institutional investors [3]

1 | | 很高，公司是三家全国性麻精药品批发企业之一，并在 15 个省 | | --- | --- | | | 市拥有区域性批发资格，销售网络覆盖全国 31 个省市及自治区， | | | 其中在四川、重庆、贵州、青海、西藏等 5 个地区具有麻精药品 | | | 经销优势。上半年公司麻精药品实现销售 17.36 亿元，同比增加 | | | 19.07%。 | | | 4、公司财务费用下降明显的原因？ | | | 答：公司持续加强对财务费用的管控，今年以来公司融资成 | | | 本下降趋势明显，上半年财务费用同比下降 1.65 亿元，同比降 | | | 幅为 30.35%。财务费用率创五年同期新低，预计未来还有进一 | | | 步下降空间。 | | | 5、公司与通用技术集团内部协同情况如何？ | | | 答：公司加速推进与通用技术集团旗下医疗机构的协同发 | | | 展，报告期内在全国 22 个省开户 104 家，其中 89 家为等级医院， | | | 同时公司在 2025 年 8 月底，与通用健康、中国医药签订战略合 | | | 作协议。三方将整合资源渠道优势，通过优化供应链全流程管理， | | | 实现药 ...