Group 1 - The strategic partnership between Fipeng Bio and Shengxiang Bio focuses on the innovation and development of AI molecular enzymes and diagnostic solutions, aiming to create more accurate and reliable next-generation diagnostic solutions [1][2] - The collaboration seeks to leverage AI technology to enhance molecular enzyme development, addressing the limitations of traditional enzyme development methods, which include long development cycles and low optimization efficiency [1][2] - Shengxiang Bio is recognized as a leading enterprise in molecular diagnostics, with a strong emphasis on clinical insights and industrialization capabilities, while Fipeng Bio is a key player in the upstream life sciences sector, providing high-performance core raw materials for in vitro diagnostics [3][4] Group 2 - The partnership represents an exploration of the "AI + industrial transformation" innovation model, aiming to unlock the potential of AI in core raw materials for in vitro diagnostics and accelerate the conversion of innovative product solutions [2] - Shengxiang Bio is listed on the Sci-Tech Innovation Board and is among the top 100 global medical device companies, committed to becoming a leader in gene technology and supporting the national precision medical system [3] - Fipeng Bio, established in 2001, is a global leader in the upstream in vitro diagnostics sector, providing reagent core materials and solutions to over 2,500 diagnostic companies across 68 countries and regions [4]

Investment Rating - The report does not explicitly state an investment rating for the industry [2] Core Insights - The pharmaceutical and biotechnology sector saw a weekly increase of 1.77%, outperforming the Wind All A index (1.49%) and the CSI 300 index (1.59%) [3][8] - Offline pharmacies and pharmaceutical distribution significantly outperformed the index with increases of 10.38% and 4.91% respectively, while in vitro diagnostics (0.77%), raw materials (0.83%), and other biological products (0.89%) lagged behind [3][9] - The report highlights the ongoing "Weight Management Year" initiative launched by the National Health Commission, emphasizing the need for continuous efforts in managing obesity and related chronic diseases [3][12] - The introduction of a pricing guide for brain-computer interface services by the National Medical Insurance Administration aims to accelerate the clinical application of new technologies [3][12] Market Weekly Review - The pharmaceutical and biotechnology sector increased by 1.77%, outperforming the Wind All A index (1.49%) and the CSI 300 index (1.59%) [3][8] - Key performers included offline pharmacies (10.38%) and pharmaceutical distribution (4.91%), while in vitro diagnostics (0.77%) and raw materials (0.83%) underperformed [3][9] - Top gainers included Kingmed Diagnostics (42.43%), Sanyou Medical (34.47%), and Dongfang Ocean (25%), while the largest declines were seen in Shuangcheng Pharmaceutical (-16.56%), Haichuang Pharmaceutical-U (-12.21%), and Ailis (-11.09%) [3][10] Industry News and Key Company Announcements - The National Health Commission's initiative on weight management aims to address obesity and its associated health risks, with a focus on chronic disease prevention [3][12] - The National Medical Insurance Administration has established pricing for brain-computer interface services, facilitating the transition of innovative technologies to clinical use [3][12] - Roche announced a collaboration with Zealand Pharma to develop a long-acting insulin analog, with a total transaction value of $5.3 billion [3][12] - Clinical trials for various drugs, including those for obesity and hypertension, have shown promising results, indicating potential market opportunities [3][14][16][18]

一边用10亿元接连完成三笔收购，继续扩大业务版图。1月，以8亿元价格收购生长激素领域头部企业 中山济海；2月，以7650万元拿下红岸基元54%的股权，成为红岸基元最大股东；3月，以自有资金向 真迈生物追加投资1.3亿元，持股比例由11.9%增加至15.55%。 一边招贤纳新，强势引入一名特别的董事，前阿里CEO、嘉御基金合伙人卫哲。卫哲的辉煌履历无需 多言。2011年从阿里巴巴辞职转战私募创投后，卫哲已经投出30多个独角兽乃至超级独角兽，其中不 乏安可创新、泡泡玛特、公牛电器等明星企业。 作者丨刘杨楠 编辑丨海腰 图源丨圣湘生物官网 此次上任圣湘生物董事，卫哲不占股、不投资，双方都在强调——这并非一次简单的走马上任，而是 一场长期战略合作的起点。 2025开年，正在"二次创业"的圣湘生物依旧攻势凶猛。 事实上，从2023年起，卫哲就陆续在公开场合表达自己对医疗的兴趣。此次合作后，圣湘生物无疑会 成为卫哲最好的"练兵场"。而对于圣湘生物而言，近两年来业务版图迅速扩张，但从实际的商业回报 上看，如今庞大的业务版图尚未落实在白纸黑字的财报上，难免显得有些"头重脚轻"。 卫哲的加入，或许能与圣湘生物"技术派"的掌舵人 ...

Investment Rating - The report does not explicitly state an investment rating for the industry [5] Core Insights - The pharmaceutical and biotechnology sector saw a weekly increase of 1.06%, underperforming compared to the Wind All A index (2.43%) and the CSI 300 index (1.39%). The AI + healthcare sector experienced a significant rebound [10][11] - Key sectors that performed well include in vitro diagnostics (4.45%), active pharmaceutical ingredients (2.08%), and hospitals (1.85%). Conversely, offline pharmacies (-0.59%) and medical devices (-0.08%) saw declines [10][11] - The government work report emphasized strengthening basic medical and health services, implementing a health-first development strategy, and promoting the coordinated development of healthcare, medical insurance, and pharmaceuticals [12][14] - On March 8, Huawei announced the establishment of a healthcare division, aiming to integrate its expertise in 5G, cloud computing, and edge computing to develop AI-assisted diagnostic solutions [12][14] Weekly Market Review - The pharmaceutical and biotechnology sector increased by 1.06%, lagging behind the Wind All A index (2.43%) and the CSI 300 index (1.39%). The AI + healthcare direction showed a notable rebound [10] - The top-performing sub-sectors included in vitro diagnostics (4.45%), active pharmaceutical ingredients (2.08%), and hospitals (1.85%), while offline pharmacies (-0.59%) and medical devices (-0.08%) were the worst performers [10][11] - The top three gaining stocks were Hotgen Biotech (38.63%), Berry Genomics (34.39%), and Anbiping (25.72%), while the top three losing stocks were Jiangsu Wuzhong (-14.34%), ST Sansheng (-9.83%), and Baile Tianheng-U (-9.44%) [12][14] Industry News and Key Company Announcements - The government work report highlighted the need to enhance basic medical services and improve the healthcare system, including reforms in public hospitals and drug procurement policies [12][14] - Huawei's new healthcare division aims to leverage its technological strengths to accelerate the development of medical AI models for clinical applications [12][14] - On March 8, Ausgen announced that the FDA accepted its new drug application for AUKONTALS, a treatment for amyotrophic lateral sclerosis, with a decision expected by October 23, 2025 [12][14] - CloudTop announced the successful administration of its mRNA personalized cancer vaccine EVM16 in a clinical trial, marking a significant milestone in its development [12][14]

全球范围内首家且唯一一家获得分子胃癌筛查IVD产品监管批准的公司。 本文为IPO早知道原创 作者｜Stone Jin 微信公众号｜ipozaozhidao 据 IPO 早 知 道 消 息 ， 中 国 证 监 会 国 际 合 作 司 于 2025 年 1 月 24 日 披 露 了 《 关 于 Mirxes Holding Company Limited（觅瑞集团控股有限公司，以下简称"觅瑞"）境外发行上市备案通知书》。 成立于2014年的觅瑞作为一家起源于新加坡的微小核糖核酸("miRNA")技术公司，中国总部在浙江 安吉，专注于在全球范围内普及疾病筛查诊断解决方案。 截至2024年10月31日，觅瑞拥有一种核心产品(即GASTROClear™)、两种其他商业化产品(即 LungClear™及Fortitude™)以及六种处于临床前阶段的候选产品。 其中，觅瑞的核心产品GASTROClear™为一个由12种miRNA生物标志物组成的用于胃癌筛查的基 于血液的miRNA检测组，其已于2019年5月获得新加坡卫生科学局的C类体外诊断证书后成功商业 化。 根据弗若斯特沙利文的资料，觅瑞是开发及商业化用于癌症及其他疾病 ...

文/梧桐数据中心 12月27日，丹娜（天津）生物科技股份有限公司北交所IPO审核获通过。 单位：万元 | 北交所 | | | | | | | --- | --- | --- | --- | --- | --- | | 公司简称 主营业务 | | 2023年营收 | 2023年净利润 | 审核结果 | 保荐/律所/审计 | | 侵袭 【 | 丹娜生物 断及其它病原微生物体外诊 | 23.671.43 | 6,847.45 | 滴付 | 招商证券/北京中伦/容诚 | 丹娜生物 主要从事侵袭性真菌病血清学早期诊断及其它病原微生物体外诊断产品的研发、生产和销售。ZHOU ZEQI（周泽奇）直接和间接共控制公司39.4465% 的股份，能够对公司经营决策产生重大影响，为公司控股股东、实际控制人。报告期内，公司营业收入分别为23,398.99万元、29,507.41万元、23,671.43万元、 11,774.01万元，扣非归母净利润分别为4,415.36万元、4,226.20万元、6,847.45万元、3,880.38万元。公司主要产品之一核心原料为鲎血细胞，鲎系国家二级保护动 物，面临无原料供应风险；尚未纳入集采，毛 ...

文/梧桐兄弟 丹娜（天津）生物科技股份有限公司（874289）申报北交所IPO于2023年12月29日获得受理，现已完成两轮问询。公司本次IPO拟募资3亿元。 丹娜生物曾于2020年11月期间申报科创板上市，但在收到首轮问询后不久即撤回科创板上市申请。 公司注册地天津市滨海新区，成立于2014年3月10日，于2023年10月16日在全国股份转让系统挂牌，并同步进入创新层。公司证券简称为"丹娜生物"，证券代码 为"874289"，公司目前注册资本4,739万元。 截止最新披露，ZHOU ZEQI（周泽奇）直接和间接共控制公司39.4465%的股份，为公司控股股东、实际控制人。 丹娜生物致力于侵袭性真菌病血清学早期诊断及其它病原微生物 体外诊断产品 领域的研发创新。 值得注意的是，自2023年以来，IVD无疑已经沦为上市失败的重灾区， 过去一段时间，就有包括翌圣生物、菲鹏生物、世和基因在内的多家IVD企业IPO折 戟，"零上市"的记录保持了许久。 一、2023年净利润大幅增加，但公司认为高增速不具有可持续性 发行人2022年度、2023年度归属于母公司股东的净利润（扣除非经常性损益前后孰低数）分别为4,226.2 ...

根据弗若斯特沙利文的资料， 觅瑞 是开发及商业化用于癌症及其他疾病早期检测 的、精准的、无 创的、可负担的、基于血液的miRNA检测试剂盒的先驱者与领导者 ； 根据弗若斯特沙利文的资料， 觅瑞 是全球为数不多的已获得分子癌症筛查行业IVD产品监管批准的公司之一，同时也是全球范围 内首家且唯一一家获得分子胃癌筛查IVD产品监管批准的公司。 今年上半年，核心产品GASTROClear的毛利率超80%。 本文为IPO早知道原创 作者｜Stone Jin 微信公众号｜ipozaozhidao 据IPO早知道消息，Mirxes Holding Company Limited（以下简称"觅瑞"）于11月4日更新招股 书，继续推进港交所主板上市进程，中金公司和建银国际担任联席保荐人。 成立于2014年的觅瑞作为一家起源于新加坡的微小核糖核酸("miRNA")技术公司，专注于在全球范 围内普及疾病筛查诊断解决方案。 截至2024年10月31日，觅瑞拥有一种核心产品(即GASTROClear)、两种其他商业化产品(即 LungClear及Fortitude)以及六种处于临床前阶段的候选产品。 其中，觅瑞的核心产品GASTROC ...