生物电子医学
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完美贴合复杂器官的“电子外衣”可实现药物精准递送
Ke Ji Ri Bao· 2026-01-29 11:19
1月28日,记者从北京航空航天大学获悉,该校医学科学与工程学院常凌乾教授团队、机械工程及 自动化学院徐晔教授团队,联合北京大学第一医院、中国医学科学院肿瘤医院、香港城市大学、美国伊 利诺伊大学等单位,研发出一款柔性可植入生物电子器件(POCKET)。该器件可个性化定制,完美贴 合于复杂形状的器官表面,并通过纳米电穿孔效应,实现安全、高效、精准的全器官药物递送或基因转 染。这一成果发表于《细胞》杂志。 研究团队表示,他们已在多种动物模型和离体人类组织上验证了POCKET的强大功能。POCKET平 台为卵巢癌预防、器官损伤修复等疾病精准治疗提供了新工具,通过融合柔性电子、微纳加工、无线供 能等技术,实现了植入式器件的精准操控与长效工作。该技术方案可扩展至肝脏、心脏、肺部等多种内 脏器官的疾病治疗、再生修复和功能调控,为未来生物电子医学的发展开辟了新范式。 据悉,基于该核心技术孵化的高科技产业化公司已完成多轮融资。首款转化产品——"Ultra-NEP超 透仪"已应用于皮肤健康等领域。未来,团队将进一步拓展其在医疗级设备领域的应用。 据研究团队介绍,这项工作始于一个令医生深感无力的临床问题:对于遗传性卵巢基因突变的患 ...
北航校史首篇Cell论文:常凌乾团队等开发器官上的“智能贴片”,实现精准高效且安全的细胞内药物递送
生物世界· 2026-01-27 12:00
编辑丨王多鱼 排版丨水成文 题图为 常凌乾 教授 传统的 药物递送方法 (例如口服、静脉注射) ,由于递送路径长、时空可控性差,在面向 结构复杂 的 器官 (例如 卵巢、肾脏 ) 疾病治疗时,长期存在着 " 药物递送 效率低、安全风险 高 "等问题 。 以 卵巢 疾病 (例如卵巢早衰) 为例, 现有递送技术,由于缺乏时空精准性,易导致生殖细胞意外转染,从而产生不 可预知风险。 至今,该领域缺乏一种 高效 且全器官时空可控 的递送技术 。 2026 年 1 月 27 日,北京航空航天大学 常凌乾 团队、 徐晔 团队、 樊瑜波 团队 , 伊利诺伊大学厄巴纳-香槟分校 余存江 团队、 香港城市大学 于欣格 团队等 ( 王玉琼 、 杜腊梅 、 吴晗 等为论文共同第一作者 ) ,在国际顶尖学术期刊 Cell 上发表了题为: An organ-conformal, kirigami-structured bioelectronic patch for precise intracellular delivery 的研究论文,这也是 北京航空航天大学首次 作为第一完成单位在 Cell 期刊上发表研究论文 。 该研究在药物递 ...
智冉医疗 A 轮融超 3 亿!君联、IDG 等一堆大佬抢着投! | 投资速递
Sou Hu Cai Jing· 2025-08-13 07:57
Domestic Investment - Daimeng Robotics completed a financing round of over 100 million yuan, focusing on high-resolution multi-modal tactile perception and intelligent solutions for various industries [1] - Zhirun Medical announced the completion of over 300 million yuan in Series A financing, aimed at advancing brain-machine interface technology for precise diagnosis of neurological diseases [2] - Leju Technology completed a B++ round of financing, with Kunlun Capital as the sole investor, marking the successful conclusion of its B round series [3][4] - Ronghe Yuanchu received B round financing from Guokun Investment, CIMC Group, and Yuanxin Fund, focusing on large-scale energy storage systems [5] - Feidu Technology completed several million yuan in strategic financing, developing a digital twin platform for various smart industries [6] - Xinghua Chip received an investment of 15 million yuan from Huitong Energy, increasing its registered capital [7] - Siweibo secured several million yuan in B round investment from Shenzhen Jiadao Green Low Carbon Investment Fund, focusing on agricultural biotechnology [8] - Guangdong Jianke went public on the Shenzhen Stock Exchange, raising 687 million yuan through the issuance of 105 million shares at 6.56 yuan each [9] - Ruimo Environmental completed a new round of financing led by Ingka Investments, focusing on recycled plastics [10] - Yongzhi Semiconductor received investment from Yida Capital to enhance its product development and capacity [11] - Lanyi Aviation completed several million yuan in Pre-A round financing, focusing on eVTOL aircraft development [12] Foreign Investment - HackQuest secured $4.1 million in Pre-A round financing, focusing on Web3 education [13] - HYLENR received $3 million in Pre-A round financing, developing low-energy nuclear reaction technology [14] - Chowdeck completed $9 million in Series A financing, focusing on local food delivery in Nigeria and Ghana [15] - FORT raised $18.9 million in Series B financing, developing a network security management platform [16] - Equillium announced up to $50 million in strategic investment for its autoimmune disease treatments [17] - Nanotein secured $3 million in strategic investment for its cell therapy products [18] - Tahoe Therapeutics completed $30 million in financing, focusing on AI-driven human cell models for drug design [19] - SetPoint Medical raised $115 million in Series D financing for its bioelectronic medicine platform [20] - August Health announced $29 million in Series B financing for its modern nursing care platform [21] IPO Queue - Jiaxin International submitted post-hearing materials for its tungsten mining project [22] - Koma Materials passed the review meeting, focusing on automotive clutch plate production [23] - Hongyuan Co. publicly offered shares, specializing in high-end transformer electromagnetic wire production [24]