Group 1 - The company, BrightGene Bio-Medical Technology Co., Ltd., issued convertible bonds totaling RMB 465 million, with a net fundraising amount of RMB 456.83 million after deducting issuance costs [3][18]. - The bonds have a maturity period of six years, from January 4, 2022, to January 3, 2028, with a face value of RMB 100 per bond [3][4]. - The coupon rates for the bonds are structured to increase over the years, starting at 0.4% in the first year and reaching 3% in the sixth year [3][4]. Group 2 - The company reported a revenue of RMB 1.28 billion for the fiscal year 2024, representing an 8.74% increase from the previous year [17]. - The net profit attributable to shareholders decreased by 3.12% to RMB 180.51 million, primarily due to increased R&D expenses [17]. - The company’s total assets increased by 2.63% to RMB 5.16 billion, indicating stable growth in its financial position [17]. Group 3 - The company focuses on innovative pharmaceutical development, emphasizing original drugs and complex formulations to meet unmet clinical needs globally [15][16]. - Key therapeutic areas include antiviral, antifungal, immunosuppressive, respiratory, oncology, and metabolic diseases, with core products in each category [16]. - The company has a strong commitment to R&D, with R&D expenses increasing by 19.65% year-on-year, reflecting its strategy of being research-driven [17]. Group 4 - The bonds are rated AA- by Dongfang Jincheng International Credit Rating Co., Ltd., with a stable outlook, indicating a strong credit profile [5][21]. - The company has established a dedicated fund management system to ensure the proper use of raised funds, adhering to regulatory requirements [20]. - The company has not experienced any defaults on bond repayments, demonstrating a stable repayment capability [21].

Company Overview - The company, 博瑞生物医药 (Suzhou) Co., Ltd., primarily engages in the research, production, and sales of high-end generic active pharmaceutical ingredients (APIs) and formulations, maintaining a strong competitive position in niche markets [3][11] - As of March 2025, the company reported total assets of 52.85 billion yuan and equity of 26.16 billion yuan, with a debt-to-asset ratio of 43.95% [5][11] - The company has a robust R&D capability, with a 25.42% year-on-year increase in R&D investment in 2024, accounting for 24.31% of its revenue [6][20] Financial Performance - In 2024, the company achieved an operating income of 2.49 billion yuan, with a gross profit margin of 43.95%, although both figures showed a decline compared to the previous year [16][20] - The revenue from the API segment was 8.85 billion yuan, while the formulation segment contributed 1.38 billion yuan, indicating a growing share of formulation sales [17][20] - The company’s total debt has been increasing, and significant investments in ongoing projects may pose challenges if market conditions change [5][7] Market Position and Competitive Landscape - The company maintains stable partnerships with major players like Teva and 恒瑞医药, benefiting from increased demand for antifungal and immunosuppressive products [6][7] - The company’s products are primarily exported, with 46.10% of its revenue coming from international sales, making it susceptible to fluctuations in global trade and currency exchange rates [7][8] - The pharmaceutical manufacturing industry is experiencing a transformation, with ongoing price governance and procurement policies impacting revenue and profit margins [14][15] R&D and Innovation - The company is advancing its pipeline of innovative drugs, including BGM0504 injection, which is in phase III clinical trials for diabetes and weight loss indications [20] - In 2024, the company received 33 new domestic and international patent authorizations, enhancing its competitive edge in the market [6][20] - The company’s focus on both generic and innovative drugs positions it well to capitalize on the growing demand for pharmaceuticals driven by an aging population and increasing healthcare needs [14][15] Industry Trends - The pharmaceutical manufacturing industry is expected to grow due to rising disposable incomes and an aging population, despite challenges from external trade dynamics [13][14] - The industry is characterized by high R&D costs and long product development cycles, necessitating strong financial and technical capabilities for sustained competitiveness [14][15] - Recent government policies aimed at supporting innovation in drug development are likely to create opportunities for companies with strong R&D capabilities [15]

博瑞生物医药（苏州）股份有限公司 为践行"以投资者为本"的上市公司发展理念，维护博瑞生物医药（苏州） 股份有限公司（以下简称"公司"）全体股东利益，增强投资者信心，基于对公 司未来发展前景的信心和对公司价值的认可，公司于 2024 年 4 月 27 日发布了 《2024 年度"提质增效重回报"行动方案》，并及时发布了 2024 年半年度评估 报告。为进一步优化公司经营，提升市场竞争力，树立良好的资本市场形象，公 司制定了《2025 年度"提质增效重回报"行动方案》，并对 2024 年度行动方案 进行年度评估。详情如下： 一、聚焦经营主业，加快推进新产品开发 公司是一家参与国际竞争的创新型制药企业。公司依靠研发驱动，聚焦于首 仿、难仿、特色原料药、复杂制剂和原创性新药，持续打造高技术壁垒，致力于 满足全球患者未被满足的临床需求。公司现有产品主要覆盖抗病毒、抗真菌、免 疫抑制、呼吸系统、抗肿瘤及代谢等治疗领域，其中抗病毒领域的核心产品包括 恩替卡韦、奥司他韦等，抗真菌领域的核心产品包括卡泊芬净、米卡芬净钠、阿 尼芬净、泊沙康唑等，免疫抑制领域的核心产品包括依维莫司、吡美莫司等，呼 吸系统领域的核心产品包括布地奈德 ...