Investment Rating - The investment rating for the company is "Buy" [2] Core Views - The company, Maipu Medical, is a leading player in the domestic neurosurgery field, focusing on high-performance implantable medical devices. The company is expected to enter a growth phase by continuously enriching its product portfolio and improving marketing channels. Key products include artificial dura mater (spinal) patches, which are expected to see accelerated market penetration due to centralized procurement, and new products like absorbable hemostatic gauze and dura mater glue, which are anticipated to provide sustained growth momentum [6][14][17]. Summary by Sections Company Overview - Maipu Medical, established in 2008 and listed on the Shenzhen Stock Exchange in 2021, specializes in high-performance implantable medical devices for neurosurgery. The company has developed a range of products including dura mater repair products and craniofacial repair systems, enhancing its capability to provide comprehensive solutions in neurosurgical repair [17][18]. Product Performance - The artificial dura mater (spinal) patch is a cornerstone product benefiting from centralized procurement, with projected revenue of 156 million yuan in 2024, reflecting a year-on-year growth of 11.46%. The product's unique bionic structure offers advantages in biocompatibility and degradability [15][32]. - Craniofacial repair products are expected to generate 80 million yuan in revenue in 2024, with a year-on-year growth of 31.05%. The superior properties of PEEK materials are anticipated to drive market penetration, replacing traditional titanium materials [16][44]. - The absorbable hemostatic gauze is projected to achieve revenue of 36 million yuan in 2024, with a year-on-year growth of 49.89%. This product is expected to break the import monopoly and rapidly gain market share [16][49]. Financial Projections - Revenue forecasts for the company from 2025 to 2027 are 371 million yuan, 491 million yuan, and 647 million yuan, with year-on-year growth rates of 33.1%, 32.5%, and 31.8% respectively. Net profit attributable to the parent company is expected to be 113 million yuan, 149 million yuan, and 199 million yuan for the same period, with growth rates of 43.6%, 31.8%, and 33.4% respectively [6][7][28]. Market Position - The company is the only domestic enterprise with a comprehensive product line in the neurosurgery field, including artificial dura mater patches, craniofacial repair systems, and absorbable hemostatic products. This diverse product structure is expected to support stable revenue growth and long-term sustainable development [18][30].

Core Viewpoint - The rise of innovative drugs in China is reshaping the global pharmaceutical industry, with significant market opportunities and challenges highlighted in the report [2]. Market Performance - Innovative drug concept stocks have shown strong performance in both A-shares and Hong Kong markets, with the Guotai Innovative Drug ETF (517110) up over 25% and the Hong Kong Innovative Drug ETF (513120) up over 60% year-to-date [2]. - Guanhao Biological, as an innovative drug concept company, saw its stock price rise by 28.56% from May 13 to June 12, 2024, reaching a peak of 18.38 yuan, with a notable single-day increase of 19.97% on June 3 [2][3]. R&D Expenditure Trends - Guanhao Biological has significantly reduced its R&D expenses, with a year-on-year decrease of 18.74% in 2024, ranking 60th among innovative drug companies [6]. - The company's R&D expenses as a percentage of revenue stand at 9.58%, ranking 50th among peers [8]. - R&D expenditures have decreased for three consecutive years, totaling 50.52 million yuan in 2022, 44.50 million yuan in 2023, and 36.16 million yuan in 2024, representing a cumulative decline of 28.4% [8][9]. R&D Personnel and Project Progress - The number of R&D personnel has decreased from 70 in 2022 to 66 in 2024, with total R&D personnel compensation dropping by 33.1% from 20.48 million yuan in 2022 to 13.71 million yuan in 2024 [9]. - The progress of ongoing projects is slow, with key projects like the artificial liver still in preclinical research and the new indication for Benvimod facing a 25.1% revenue decline in 2024 [9][10]. Competitive Landscape - Competitors have successfully launched products, such as Zhenghai Biological's "Haiyu" active biological bone filling material, which has entered the sales system in many hospitals [10]. - Guanhao Biological's recent strategic adjustments have not yet yielded significant performance support, while traditional biological materials face intensified market competition [10]. Financial Performance - Guanhao Biological's revenue fluctuated from 377 million yuan in 2022 to 404 million yuan in 2023, then back to 377 million yuan in 2024, reflecting a 6.6% year-on-year decrease due to price drops from centralized procurement policies [12]. - The company's net profit has also seen significant fluctuations, with a loss of 300 million yuan in 2022, a profit of 31 million yuan in 2023, and a further decline to 27.42 million yuan in 2024, down 11.57% year-on-year [13].