Core Viewpoint - Chengda Biological has terminated six vaccine research and development projects since early December, including five under the "Human Vaccine R&D Project" and one under the "Biotechnology Product R&D Production Base Project" due to market dynamics and technical feasibility assessments [1][2]. Group 1: Project Termination - The company announced the termination of the "b-type influenza Haemophilus influenzae type b conjugate vaccine" development project and five other sub-projects, including the pentavalent rotavirus vaccine, due to a lack of commercial viability and feasibility [1][2]. - The total planned investment for the "Human Vaccine R&D Project" was 837 million yuan, fully funded by raised capital, focusing on multi-valent and innovative vaccines [1]. Group 2: Market Competition - The pentavalent rotavirus vaccine, previously a key focus, faces intense competition with the successful launch of the world's first hexavalent rotavirus vaccine by China National Pharmaceutical Group, leading to a reassessment of its commercial potential [2]. - The domestic rabies vaccine market has become increasingly competitive, with 23 marketed products and 19 in clinical development, impacting Chengda Biological's market share significantly [3]. Group 3: Financial Performance - Chengda Biological's revenue has declined over the past three years, with reported revenues of 1.815 billion yuan, 1.750 billion yuan, and 1.675 billion yuan, reflecting year-on-year decreases of 13.08%, 3.58%, and 4.22% respectively [3]. - For the first three quarters of 2025, the company reported revenues of 1.096 billion yuan, a year-on-year decline of 15.88%, and a net profit of 165 million yuan, down 50.01% [4].

Core Viewpoint - The company, Liaoning Chengda Biological Co., Ltd., is convening its second extraordinary general meeting of shareholders in 2025 to discuss adjustments to its fundraising projects and internal investment structure, including the termination of certain research projects and the allocation of funds to new initiatives [1][18]. Meeting Details - The second extraordinary general meeting of shareholders will be held on December 23, 2025, at 9:30 AM in Shenyang, Liaoning Province [4]. - The meeting will utilize a combination of on-site and online voting methods, with specific time slots for voting [2][6]. Fundraising Project Adjustments - The company plans to optimize the internal investment structure of its "Human Vaccine Research Project" by terminating five research sub-projects and reallocating unused funds to other ongoing and new sub-projects, specifically the "High-Value Pneumococcal Polysaccharide Conjugate Vaccine" and "High-Dose Influenza Virus Split Vaccine" [19][30]. - A total of 100 million yuan will be specifically allocated to increase capital in its wholly-owned subsidiary, Chengda Biological (Benxi) Co., Ltd., to support the implementation of the "High-Dose Influenza Virus Split Vaccine" [19][43]. Project Timeline Extensions - The fundraising usage period for the "Human Vaccine Research Project" and "Biotechnology Product R&D Production Base Project" has been extended to December 2028 to adapt to global macroeconomic changes and industry trends [20][46]. - The adjustments made will not affect the total planned investment amount for the "Human Vaccine Research Project" [41]. Financial Management and Compliance - The company has established a special account for the management of the raised funds, ensuring that all funds are used specifically for the designated projects [45]. - The adjustments and extensions have been approved by the company's board and will be submitted for shareholder approval at the upcoming meeting [25][46].