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海正药业: 浙江海正药业股份有限公司第十届董事会第六次会议决议公告
Zheng Quan Zhi Xing· 2025-08-25 17:05
证券代码:600267 证券简称:海正药业 公告编号:临 2025-43 号 浙江海正药业股份有限公司 第十届董事会第六次会议决议公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏,并对其内容的真实性、准确性和完整性承担法律责任。 浙江海正药业股份有限公司(以下简称"公司")第十届董事会第六次会 议于 2025 年 8 月 22 日下午在公司会议室以现场加通讯方式召开。应参加本次会 议董事 9 人,亲自参加会议董事 9 人,公司监事及高管人员列席了会议。本次会 议的召开程序符合《公司法》和《公司章程》的规定,会议合法有效。本次会议 由公司董事长肖卫红先生主持,经与会董事认真讨论研究,会议审议并通过了如 下决议: 一、关于计提资产减值准备的议案; 同意 9 票,反对 0 票,弃权 0 票。 详见《浙江海正药业股份有限公司关于计提资产减值准备的公告》,已登载 于 2025 年 8 月 26 日的《中国证券报》 《上海证券报》 《证券时报》和上海证券交 易所网站(www.sse.com.cn)上。 二、关于前期会计差错更正的议案; 同意 9 票,反对 0 票,弃权 0 票。 本议 ...
辉瑞撤资余波未平:海正药业遭遇营收三连降,创新转型前路迷雾重重|创新药观察
Hua Xia Shi Bao· 2025-08-01 14:09
Core Viewpoint - After parting ways with Pfizer, Zhejiang Haizheng Pharmaceutical Co., Ltd. is facing significant challenges in its development despite recent approval for its active pharmaceutical ingredient, fumarate bedaquiline [2] Group 1: Company Background - Haizheng Pharmaceutical, founded in 1956 and listed in 2000, is a state-controlled comprehensive pharmaceutical group with a diverse portfolio including chemical drugs, biological drugs, and veterinary drugs [3] - The company’s core products include the self-developed first-class new drug Haibomab, a cholesterol absorption inhibitor, and other medications for liver bile accumulation treatment [3] Group 2: Partnership with Pfizer - The partnership with Pfizer began in September 2012, creating Haizheng Pfizer Pharmaceutical Co., Ltd. with a total investment of $295 million, where Haizheng held a 51% stake [3][4] - Initially, the collaboration was beneficial, significantly boosting Haizheng's revenue through the exclusive production of off-patent antibiotics [4] - However, production issues at Pfizer's overseas factories led to a significant revenue drop, and by 2017, Pfizer completely exited the partnership [4] Group 3: Financial Performance - Haizheng Pharmaceutical has experienced a continuous decline in revenue from 2022 to 2024, with year-on-year decreases of 0.82%, 13.82%, and 5.65% respectively [5][6] - In Q1 2025, the company reported revenue of 2.632 billion yuan, a 3.48% decrease year-on-year, and a net profit of 194 million yuan, down 21.85% [5] Group 4: Market Challenges - The company’s performance has been adversely affected by centralized procurement policies, leading to a significant reduction in market share for key products [6] - In 2023, the revenue from self-operated pharmaceutical preparations decreased by 10.41 billion yuan, indicating a substantial impact from procurement policies [6] Group 5: Innovation and R&D - Haizheng's self-developed drug Haibomab has shown promising sales growth, reaching over 400 million yuan in 2023, with potential peak sales estimated at 1.954 billion yuan [7] - The company has recently received approval for HS387, targeting advanced ovarian cancer and non-small cell lung cancer, but faces intense competition in these markets [8] - R&D investment has fluctuated, with 2024's R&D expenditure at 416 million yuan, representing 4.25% of revenue, indicating a focus on innovation despite financial pressures [10] Group 6: Future Prospects - The approval of fumarate bedaquiline is a positive development, but the company faces challenges in scaling production and market entry [9] - The overall effectiveness of Haizheng's R&D platforms and the impact of past collaborations with Pfizer on current innovation efforts remain uncertain [10]
海正药业20250720
2025-07-21 00:32
Summary of Key Points from the Conference Call Company and Industry Overview - **Company**: 海正药业 (Haizheng Pharmaceutical) and 博瑞生物 (Borui Biopharmaceutical) - **Industry**: Pharmaceutical and Biotechnology Core Insights and Arguments Haizheng Pharmaceutical 1. **Transformation and Innovation**: Haizheng is actively transforming by enhancing its innovative drug pipeline through internal R&D and external collaborations, focusing on products like HS387 and Haibo Maibu tablets, which saw a 100% annual sales growth after entering the medical insurance system [2][3] 2. **Leadership Changes**: The new leadership under CEO Xiao has brought significant changes, improving operational efficiency and achieving record high net profits [8][9] 3. **Product Strategy**: The company is implementing a "big product" strategy, aiming for substantial sales from key products, including Haibo Maibu, projected to reach sales of 800 to 1,000 million [9] Borui Biopharmaceutical 1. **Growth Since Spin-off**: Since its spin-off in 2019, Borui has expanded its commercial product line from 1 to 7.5 products, with revenue increasing from 200 million to 1.63 billion, reflecting a compound annual growth rate of approximately 35% [2][5] 2. **Innovative Drug Development**: Borui has made significant strides in innovative drugs, including the launch of Anruixin (Zebetomab), the first Class 1 innovative drug in China, and is focusing on autoimmune and tumor immunity fields [6][7] 3. **ADC Platform**: Borui's unique approach in the ADC (Antibody-Drug Conjugate) platform, utilizing dual payload toxins and stable linker technology, enhances efficacy and reduces toxicity, positioning it competitively in the market [12][13] Additional Important Insights 1. **Market Expansion**: Borui is exploring the pet economy and has established a leading position in veterinary medicine, while also expanding into medical aesthetics and e-commerce channels [10][9] 2. **Future Revenue Goals**: Borui aims to achieve over 7.5 billion in revenue by 2029-2030, with expectations of significant contributions from various product lines [27][28] 3. **IPO Plans**: Borui is actively pursuing an IPO on the Sci-Tech Innovation Board, with a pre-IPO valuation of 13 billion as of late 2022, and is expected to meet listing conditions by June 2023 [29][22] This summary encapsulates the key developments and strategic directions of Haizheng Pharmaceutical and Borui Biopharmaceutical, highlighting their growth trajectories, innovative strategies, and market positioning within the pharmaceutical industry.
海正药业新崛起战略有这些看点
Guo Ji Jin Rong Bao· 2025-06-03 06:53
Core Viewpoint - The core strategy of Haizheng Pharmaceutical is to return to the top tier of the domestic market by focusing on human medicine while developing animal medicine and health products as complementary wings [1] Group 1: Business Strategy and Development - Haizheng Pharmaceutical aims to establish a diversified development pattern with a focus on human medicine and two wings: animal medicine and health products [1] - The company has transformed its original raw material plant into a biopharmaceutical industrial park covering over 1,500 acres, encompassing high-end biopharmaceuticals, injectable and oral formulations, and export raw materials [1][3] - The company has been exporting raw materials to over 70 countries and regions since 1992, with more than 400 overseas clients, including major global pharmaceutical companies [3] Group 2: Production and Quality Control - Haizheng Pharmaceutical emphasizes the importance of high-quality raw materials, with production bases in Taizhou, Fuyang, and Nantong, featuring a complete production line with fermentation capacity of 17,000 cubic meters and synthesis capacity of 2,300 cubic meters [6] - The Fuyang base has established an international standard QEHS system and has successfully undertaken CMO orders from international giants like Merck and Codexis [6][12] - The company has passed inspections from various global regulatory bodies, including WHO, FDA, and EMA, demonstrating its commitment to quality [12] Group 3: Innovation and Product Development - The company has accelerated its transition from raw materials to formulation business, with its subsidiary Hanhui Pharmaceutical achieving significant sales growth [8][10] - Haizheng Pharmaceutical has developed its first-class innovative drug, Haibomab, which has enriched its product line [10] - The company has successfully completed technology transfers for several original products, filling gaps in domestic technology transfer for original products [10] Group 4: Animal Health Sector - The animal health sector is a key focus for Haizheng Pharmaceutical, leveraging its expertise in human medicine standards to create high-quality veterinary products [14] - The company has established a comprehensive product matrix covering pets, pigs, and ruminants, with a commitment to rigorous quality standards [15] - Haizheng Animal Health has achieved significant milestones, including the first domestic deworming drug with sales exceeding 100 million and successful market entries in countries like Vietnam [15]