Core Viewpoint - The announcement from Jiangsu Wuzhong Pharmaceutical Development Co., Ltd. (ST Wuzhong) regarding the termination of the exclusive distribution agreement for AestheFill in mainland China has highlighted a significant dispute involving multiple parties, including REGEN Biotech and Aimeike [2][4]. Company Overview - ST Wuzhong's subsidiary, Datuo Medical, received a termination notice from REGEN, which has been acquired by Aimeike, leading to the withdrawal of Datuo Medical's exclusive rights to distribute AestheFill, a popular facial filler in China [2][3]. - AestheFill, developed by REGEN, is a medical aesthetic injection that stimulates collagen regeneration to improve skin tightness and reduce wrinkles [3]. Financial Impact - In 2024, AestheFill's sales in China reached 326 million yuan, accounting for approximately 20% of ST Wuzhong's total revenue [4][6]. - Datuo Medical reported a revenue of 96 million yuan with a gross profit of 37 million yuan, marking its first appearance in ST Wuzhong's significant subsidiaries list [6]. - There is a discrepancy of 230 million yuan between Datuo Medical's reported revenue and AestheFill's sales figures, raising questions about revenue attribution [6]. Legal and Compliance Issues - Aimeike's reasons for terminating the agreement include allegations of Datuo Medical transferring its rights to its parent company, Wuzhong Meixue, and ST Wuzhong's history of financial misconduct leading to regulatory penalties [5][8]. - ST Wuzhong refuted these claims, asserting that no transfer of rights occurred and that the agreement did not stipulate that administrative penalties would trigger termination [5][8]. Market Dynamics - The dispute over AestheFill's distribution rights has not yet significantly impacted the operations of medical aesthetic institutions, which continue to procure the product from Wuzhong Meixue [9][10]. - Concerns remain regarding potential brand and trademark disputes, especially with the recent change in the registration agent for AestheFill [11]. Strategic Importance - For Aimeike, regaining control over AestheFill aligns with its internationalization strategy and aims to enhance its product portfolio, especially as its core product lines face declining growth rates [12][13]. - AestheFill has been approved in 34 countries, positioning it as a competitive product in the global market [14]. Future Outlook - ST Wuzhong has warned investors that the termination of AestheFill's distribution rights could lead to a significant decline in revenue and profits for its medical aesthetics segment in the second half of the year [15]. - Aimeike has indicated that REGEN's new factory in South Korea will ensure a stable supply of AestheFill to meet global demand, including the Chinese market [15].