CLDN18.2 ADC
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创新药飙升,益方生物大涨超9%,科创创新药ETF汇添富(589120)强势涨超3%,科创创新药成果加速落地!
Sou Hu Cai Jing· 2025-12-19 02:43
流动性方面,科创创新药ETF汇添富盘中换手5.27%,成交2366.22万元。拉长时间看,截至12月18日,科创创新药ETF汇添富近1年日均成交3756.23万元。 截至2025年12月19日 10:14,上证科创板创新药指数(950161)强势上涨3.26%,成分股成都先导(688222)上涨10.44%,益方生物(688382)上涨9.82%,悦康药业 (688658)上涨6.82%,阳光诺和(688621),泽璟制药(688266)等个股跟涨。科创创新药ETF汇添富(589120)上涨3.02%,最新价报0.85元。(以上所列股票仅为 指数成份股,无特定推荐之意) 12月18日,益方生物在互动平台回答投资者提问时表示,目前公司主要有2款对外授权产品,其中就贝福替尼产品,公司已与贝达药业在合作区域内(包括 中国内地和香港、台湾地区)达成授权合作。 从资金净流入方面来看,科创创新药ETF汇添富近4天获得连续资金净流入,最高单日获得1415.88万元净流入,合计"吸金"3017.86万元,日均净流入达 754.46万元。(数据来源:Wind) 消息面上,近日,国家医保局、人力资源社会保障部公布《国家基本医疗保 ...
里昂:升信达生物(01801)目标价至111.4港元 中绩胜预期
Zhi Tong Cai Jing· 2025-09-01 09:47
Core Viewpoint - Credit Suisse has raised its sales forecasts for Innovent Biologics (01801) for this year, next year, and 2027 by 2.7%, 0.8%, and 2.8% respectively, while also increasing net profit forecasts by 90.4%, 25.3%, and 25.3% for the same years, with a target price adjustment from HKD 108.4 to HKD 111.4, maintaining an "outperform" rating [1] Group 1 - Innovent Biologics reported a strong mid-year performance, with sales increasing by 50.6% year-on-year and achieving a net profit of RMB 834 million, exceeding expectations [1] - The approval of GLP-1 dual agonists and the upcoming launch of IL-23 are expected to further drive profitability growth for Innovent Biologics [1] - The highly anticipated PD-1/IL-2 drug IBI363 is ready for a global MRCT trial targeting I/O recurrent squamous non-small cell lung cancer, while the CLDN18.2 ADC is undergoing a second MRCT trial for pancreatic cancer [1]
信达生物(1801.HK):上市产品销售延续强势 管线全球开发进入关键阶段;上调目标价
Ge Long Hui· 2025-08-31 01:10
Core Viewpoint - The company demonstrates strong product revenue growth, reaffirming its excellent commercialization management capabilities and clinical value of its products, with multiple research catalysts expected in the upcoming years [1][2] Group 1: Financial Performance - In 1H25, product revenue is expected to grow by 37% year-on-year to 5.2 billion RMB, driven by sustained sales of existing products and the launch of five new products [1] - Licensing revenue significantly increased to 670 million RMB, primarily from a $80 million upfront payment from Roche for DLL3 ADC collaboration [1] - Net profit reached 830 million RMB, marking a turnaround from losses and further expanding compared to 2H24 [1] - SG&A expense ratio decreased by 8.3 percentage points, although a slight increase is anticipated in 2H25 due to new product launches [1] - R&D expenses decreased by 28% year-on-year, but are expected to rise in 2H due to the global Phase III launches of PD-1/IL2 and CLDN18.2 ADC [1] Group 2: Research and Development - The international multi-center Phase III trials for PD-1/IL2 dual antibody have received FDA and NMPA approval, with plans to enroll approximately 600 patients globally [2] - Key clinical trials for CLDN18.2 ADC in treating 2L+ pancreatic cancer are set to begin in 2H25 [2] - Several candidates with new mechanisms are in early global development, including EGFR/B7-H3 dual-target ADC and GPRC5D/BCMA/CD3 tri-antibody [2] - In the non-oncology field, two Phase III data readouts for Marsdu peptide are anticipated in 2H25, focusing on diabetes with obesity and high-dose weight loss [2] Group 3: Future Outlook - Management projects product revenue to exceed 20 billion RMB by 2027, with over 20 commercialized products, and at least five pipeline drugs entering global multi-center Phase III studies by 2030 [1] - The target price has been raised to 105 HKD based on 1H25 performance and management guidance, reflecting a 2% increase in revenue forecasts for 2025-27 [2]