截至2025年6月30日，百奥赛图已累计签署约280项药物合作开发、授权及转让协议。公司子品牌百奥动 物已建立数千种基因编辑动物/细胞模型，拥有全球规模领先的靶点人源化小鼠库，并为全球客户提供 临床前药理药效研究、基因编辑服务与模型构建等全链条能力支持。百奥赛图总部位于北京，并在中国 (江苏海门、上海)、美国(波士顿、旧金山、圣地亚哥)及德国海德堡等地设有分支机构，形成了覆盖全 球的研发与运营网络。 百奥赛图是一家以创新技术驱动新药研发的国际性生物技术公司。公司围绕新药研发中"获取高质量源 头抗体分子"与"实现高转化体内验证"两大行业痛点，打造了全球领先的"双引擎平台"体系：一方面， 通过全球范围内抗体基因人源化程度最高的小鼠平台之一RenMice全人抗体平台，构建出覆盖1000余个 潜在可成药靶点、超过百万条真实全人抗体序列的"千鼠万抗"抗体资源库，为药企提供高确定性、高成 药性的源头分子；另一方面，以全球规模领先的靶点人源化小鼠库为基础，提供数千种高精度、多疾病 领域的体内验证模型与服务，用于双抗、ADC、核酸药物等多类型创新疗法的药效、安全性与机制研 究。依托"全人抗体库+靶点人源化小鼠库"双业务体系， ...

近日，临床前CRO企业百奥赛图正式登陆上交所科创板，引发市场关注。公司凭借"千鼠万抗"计划与 RenMice全人抗体平台，在生物医药领域具有一定技术积累与业务布局。然而，其招股书及财务数据背 后，却透露出盈利依赖研发压缩、关联交易占比高、专利侵权诉讼、未弥补亏损巨大等多重风险，值得 投资者警惕。 一、扭亏为盈背后的"成本压缩术"：研发投入大幅缩水 从财务表现看，百奥赛图在2022年至2024年间营业收入稳步增长，归母净利润从-6.02亿元转为正收益 3354.18万元，今年前三季度更是实现1.14亿元净利润，看似走出亏损泥潭。 然而，仔细观察发现，公司同期研发费用从6.99亿元骤降至3.24亿元，研发人员总数从627人减至337 人，专职研发人员更是从58人锐减至5人。2022至2024年间，公司营收增长4.46亿元，研发费用却下降 3.75亿元。这引发市场质疑：盈利改善是否更多来自"节流"而非真正的业务成长？公司解释称"大规模 研发阶段已结束"，但作为一家以技术为核心竞争力的生物医药企业，研发投入的持续性仍是其长期价 值的关键。 二、关联交易与专利诉讼双重隐患 抗体开发业务是百奥赛图的重要增长点，2022至 ...

Core Insights - The company, Baiaosaitu, has secured two significant licensing agreements within a month, highlighting the value of its proprietary RenMice fully human antibody development platform [1][2] - The company has established itself as a leader in the innovative molecular licensing space in China, with a total of 280 licensing projects, including partnerships with seven of the top ten global pharmaceutical companies [2][3] Group 1: Licensing Agreements - On September 16, Baiaosaitu signed an antibody licensing agreement with Tubulis, which will utilize Baiaosaitu's RenMice platform for developing innovative ADC therapies [1] - Just over a week prior, on September 4, Baiaosaitu entered into an antibody option and evaluation agreement with Merck to assess antibodies developed using the RenMice platform [1] - These agreements demonstrate the international competitiveness and drug conversion potential of Baiaosaitu's fully human antibody platform [1] Group 2: Financial Performance - In the first half of the year, Baiaosaitu achieved a revenue of 621 million yuan, representing a year-on-year growth of over 51% [2] - The company's gross margin remained high at approximately 74.4%, with a net profit of 48 million yuan [2] - The stock price of Baiaosaitu increased significantly, from a low of 7.8 HKD per share to a high of 28.58 HKD per share, reflecting a growth of over 320% since the beginning of the year [2] Group 3: Research and Development - Baiaosaitu's R&D expenses for the first half of the year were approximately 209 million yuan, an increase of 29.3% year-on-year [4] - The company has obtained 195 authorized patents and submitted 496 patent applications, focusing on expanding its fully human antibody library [4] - Baiaosaitu aims to enhance its core advantages in target humanized mouse and fully human antibody discovery by integrating AI and automation into its R&D processes [4]

Core Viewpoint - The stock of Baiaosaitu-B (02315) surged over 10% following the announcement of a global licensing agreement for antibody molecules with BeiGene, indicating strong market confidence in the company's growth prospects and collaboration with established partners [1] Company Developments - Baiaosaitu has entered into a global licensing agreement with BeiGene, which includes an upfront payment and potential milestone payments based on development and commercialization, as well as royalties based on net sales [1] - The collaboration builds on an existing relationship where BeiGene had previously obtained a license for Baiaosaitu's RenMice fully human antibody platform, reflecting a deepening partnership [1] Financial Performance - Dongwu Securities reported that Baiaosaitu's operational performance in the first half of the year exceeded expectations, with significant growth in business development (BD) activities [1] - The company is expected to achieve over 40% growth in its antibody BD business and maintain over 40% growth in animal models, with preclinical CRO growth nearing 60%, leading to an overall revenue growth exceeding 40% [1]

Core Viewpoint - 百奥赛图-B (02315) has seen a significant increase in stock price following the announcement of a global licensing agreement with BeiGene for antibody molecules, indicating strong market confidence in the company's growth prospects [1] Group 1: Licensing Agreement - 百奥赛图 has entered into a global licensing agreement with BeiGene for antibody molecules, which includes an upfront payment and potential milestone payments based on development and commercialization [1] - The agreement builds on an existing collaboration where BeiGene had previously obtained a license for 百奥赛图's RenMice fully human antibody platform, indicating a deepening partnership [1] Group 2: Financial Performance - 东吴证券 reported that 百奥赛图's operating performance in the first half of the year exceeded expectations, with business development (BD) continuing to grow [1] - The company is expected to achieve over 40% growth in its antibody BD business in the first half of 2025, with animal models maintaining over 40% growth and preclinical CRO growth nearing 60% [1] - Overall revenue growth for 百奥赛图 is projected to exceed 40%, supported by a recovery in domestic industrial clients and a rapid increase in orders [1]

Core Viewpoint - 百奥赛图-B has seen a significant stock price increase following the announcement of a global licensing agreement with BeiGene for antibody molecules, indicating strong market confidence in the company's growth prospects [1] Group 1: Licensing Agreement - 百奥赛图 has entered into a global licensing agreement with BeiGene, which includes an upfront payment and potential milestone payments based on development and commercialization [1] - The agreement expands upon an existing collaboration where BeiGene had previously obtained a license for 百奥赛图's RenMice fully human antibody platform, showcasing the deepening partnership between the two companies [1] Group 2: Financial Performance - According to Dongwu Securities, 百奥赛图's operating performance in the first half of the year exceeded expectations, with business development (BD) continuing to grow [1] - The company has seen a rapid increase in orders, with a projected growth rate of over 40% for its antibody BD business in the first half of 2025, alongside a 40%+ growth in animal models and nearly 60% growth in preclinical CRO services [1] - Overall revenue growth for 百奥赛图 is expected to exceed 40%, driven by a moderate recovery in domestic industrial clients [1]