实现科技与伦理的动态适配，需从事后纠偏转向过程嵌入，将伦理原则前移至技术研发、应用部署的全 流程 脑机接口可增强认知能力，基因编辑可改变生理特征，但"为人"的关键仍是自我意识的连续性、自主决 策能力以及为决策负责的态度 "善"不是抽象的道德概念，而是要确保技术发展不偏离人类共同利益，让所有人都能从技术进步中受 益，实现人与技术的和谐共生 文 |《瞭望》新闻周刊记者 扈永顺 鲁晓：传统伦理治理多在技术成熟后进行补救，难以适应当前技术的飞速发展。实现科技与伦理的动态 适配，需从事后纠偏转向过程嵌入，将伦理原则前移至技术研发、应用部署的全流程，推动形成可解 释、可审计、可追责的技术发展路径。同时，算法决策、自动生成内容等技术打破了传统责任边 界，"谁来负责、如何负责"变得模糊，需重塑技术发展的责任体系，通过制度安排明确开发者、平台、 使用者和监管部门的责任，形成可追责、可审计、可纠偏的责任闭环，让科技向善从道德倡导化为制度 约束。 随着生成式人工智能、基因编辑、量子计算等颠覆性技术的迅猛发展，人类社会正面临着前所未有的伦 理挑战。例如生殖细胞编辑的伦理争议持续发酵；Neuralink等脑机接口涉及意识上传、记忆篡改 ...

【文/观察者网 熊超然】 2008年，当爱泼斯坦因招嫖而被定罪后，哈佛大学悄然决定，不再接受这名"慷慨捐赠者"的捐款。 要知道，此前十年间，爱泼斯坦已向哈佛捐赠了多达910万美元。然而六年之后，爱泼斯坦仍在想方设 法，将其财富输送给哈佛一些享誉世界的科学家，其中包括从事前沿遗传学研究的人士，该领域长期以 来一直是他的个人兴趣所在。 美国司法部公布的电子邮件显示，爱泼斯坦计划设立一家投资公司，表面上由哈佛生物学家运营，但资 金由他本人控制。和爱泼斯坦共同设立这家公司的著名遗传学研究创新者乔治·丘奇（George Church），目前仍在哈佛大学生物启发工程怀斯研究所领导一个关键部门，他已参与创立了至少50家生 物技术公司，并以长期致力于利用基因编辑复活猛犸象而闻名。 在哈佛大学，爱泼斯坦将大部分资金投入到该校的科研人员身上，并与丘奇和另一名生物学家马丁·诺 瓦克（Martin Nowak）的关系尤为密切。 美国有线电视新闻网（CNN）当地时间2月19日的独家报道披露，此前未公开的照片似乎显示，这两名 教授曾到访过爱泼斯坦臭名昭著的私人岛屿。在哈佛领导层宣布与这名声名狼藉的金融家断绝关系数年 后，爱泼斯坦仍试图将 ...

Core Viewpoint - The research highlights the potential of in vivo base editing as a viable strategy to alleviate symptoms associated with Snijders Blok-Campeau Syndrome (SNIBCPS), a genetic neurodevelopmental disorder caused by mutations in the CHD3 gene [2][10]. Group 1: Disease Overview - Snijders Blok-Campeau Syndrome (SNIBCPS) is an autosomal dominant genetic disorder caused by pathogenic mutations in the CHD3 gene, first described in 2018, with over 100 reported cases [5]. - Key clinical features of SNIBCPS include global developmental delay, language delay, intellectual disability, hypotonia, facial dysmorphism, and brain structural abnormalities, often accompanied by autism spectrum disorder (ASD) [5]. Group 2: Research Findings - The research team developed a humanized mouse model (Chd3 hR1025W/+) that exhibited communication, cognitive, and autism-related behavioral deficits [3][7]. - A base editor, TeABE, was designed to correct the A•T base pair mutation, and intravenous delivery via a dual AAV system restored CHD3 protein levels and improved cognitive and autism-like behaviors in the mouse model [3][8]. - In non-human primates (NHP), intrathecal delivery of AAV9 carrying TeABE achieved widespread brain transduction and base editing, supporting the clinical translational feasibility of this approach [3][8]. Group 3: Implications for Treatment - The findings establish in vivo base editing as a feasible treatment method for CHD3-related neurodevelopmental disorders, demonstrating that precise single-base editing in the brain postnatally can restore protein dosage and function [10].

Group 1 - The total asset balance of asset management in China is projected to reach 120 trillion yuan by the end of 2025, representing a year-on-year growth of 13.1% [1] - The scale of asset management products is rapidly increasing, with new assets primarily directed towards interbank deposits and certificates of deposit, totaling 28.7 trillion yuan by the end of 2025, which is an 18.9% increase year-on-year [1] - During the Spring Festival holiday, travel bookings have significantly increased, with hotel bookings up over 80% and ticket sales up 54% compared to last year [1] Group 2 - The UK job market continues to weaken, with the unemployment rate rising to 5.2% in the fourth quarter of 2025, the highest level in nearly five years, and the total number of unemployed reaching approximately 1.883 million, a year-on-year increase of 28.1% [2] - The Canadian Consumer Price Index (CPI) for January showed a month-on-month change of 0%, below the expected 0.2% [3] - The New York Federal Reserve's manufacturing index for February is reported at 7.1, slightly above the expected 6.98 [3]

格隆汇2月17日｜近日，中国农业科学院作物科学研究所作物精准育种技术创新团队在我国自主知识产 权基因编辑工具Cas12i3的基础上，成功开发出新型碱基编辑系统，并利用该系统创制出抗除草剂水稻 新种质。 作为我国自主研发的基因编辑工具，Cas12i3相较于国外主流工具，具有体积更小、编辑适用 范围更广等独特优势。然而，依托Cas12i3的腺嘌呤碱基编辑器目前尚未成功开发，Cas12i3的胞嘧啶碱 基编辑器在植物中编辑效率比较低。因此，针对Cas12i3开发高效的碱基编辑系统，对丰富我国育种技 术工具箱具有重要意义。 研究团队构建了5个不同版本碱基编辑器，并分别对他们进行编辑效率系统评 估。其中一种结合了两个特定功能单元的架构表现最优，能显著提升腺嘌呤、胞嘧啶碱基编辑效率，并 扩大碱基编辑窗口。在稳定遗传的水稻植株中，优化后的碱基编辑工具可将原有编辑效率分别提升4.78 倍和3.35倍。 业内人士认为，这项研究为作物基因功能解析和精准遗传改良提供了重要工具和技术支 撑。国际学术期刊《植物学报》日前发表了相关研究成果。 ...

粉红色的菠萝 爆米花味番茄口感和普通番茄差不多,只是香味更浓郁。 主笔:于梅君 你见过果肉粉嫩的菠萝、闻起来像爆米花的番茄吗?一系列特色新品种,正刷新人们对果蔬的固有印象。 其中,果肉粉嫩清甜的粉色菠萝,凭借高颜值与独特风味,在春节前夕备受青睐,成为年货选购新热点。 如今,科研人员运用基因编辑、分子育种等前沿技术,正将寻常果盘升级为充满创意的"风味实验室"。 粉色菠萝亮相高颜值如何得来 2026年1月,来自哥斯达黎加的"Pinkglow粉色光芒"菠萝,凭借梦幻粉红色果肉走红社交媒体,成为水果界新 晋顶流,更在春节前凭借高颜值与稀缺属性,成为高端年货市场的"抢手货"。 尽管单颗售价高达800-1000元、礼盒装突破2000元,但其粉嫩果肉切开瞬间的视觉冲击(网友评价"整个厨 房都亮了")与独特口感,仍让它成为一些年轻消费者送礼首选,有高端西餐厅将其切成爱心形状,打造网红 打卡菜品。 原本金黄色的菠萝为何会变粉嫩?变色秘诀藏在基因里:普通菠萝成熟时,番茄红素会在转化酶作用下变成 β-胡萝卜素,呈现黄色。而科学家通过生物技术,抑制了转化酶活性,让番茄红素大量留存,最终将果肉染成 诱人的粉红色。 这款粉菠萝的番茄红素 ...

Company Developments - Corteva's board approved a plan to split the company into two independent publicly traded entities, expected to be completed in the second half of 2026. "New Corteva" will focus on crop protection (including biopesticides), while "SpinCo" will concentrate on seeds and emerging technologies such as gene editing and biofuels [2] Product Development Progress - The company plans to launch the biostimulant seed treatment Lumidapt Valta LS in the U.S. market for the 2026 planting season, which has completed the regulatory approval phase and aims to enhance crop yields [3] Performance Strategy - Corteva provided preliminary performance outlook for 2026, expecting a midpoint of $4.18 billion in earnings before interest, taxes, depreciation, and amortization (EBITDA), reflecting the company's confidence in its growth potential [4] Strategic Initiatives - Corteva has established a multi-year collaboration with Profluent Bio to leverage AI technologies, such as the OpenCRISPR-1 genome editing tool, to accelerate the development of resilient and high-yield crop varieties, which may drive long-term innovation [5]

Group 1 - The core viewpoint emphasizes that technology is reshaping society, international relations, and human life at an unprecedented pace, while global governance struggles to keep up with these changes [3][4] - There exists a fundamental paradox in global technology governance, where the revolutionary impact of technology contrasts sharply with the national and local nature of governance, leading to significant gaps [3][4] - The article stresses the importance of collaborative governance involving multiple international stakeholders, including governments, international organizations, tech companies, and communities, to address the digital divide and ensure inclusive participation in global technology governance [3][4] Group 2 - Global technology governance is described as a pressing collective action challenge of the 21st century, testing humanity's wisdom, foresight, courage, and spirit of cooperation [4] - The article argues that while technological progress cannot and should not be halted, it is crucial to learn how to steer its direction effectively [4]

Core Insights - China's effective invention patents reached 5.32 million, with high-value patents accounting for 43.1%, marking a significant milestone in intellectual property (IP) strength and innovation in emerging fields [1] - The World Intellectual Property Organization's 2025 Global Innovation Index Report indicates that China has entered the top ten globally for the first time, reflecting accelerated innovation vitality [1] Group 1: Patent Development - The number of effective invention patents in strategic emerging industries is projected to reach 1.534 million by the end of 2025, representing nearly 70% of high-value patents [1] - China leads globally in artificial intelligence patents and has established a dense patent layout in future industries such as quantum technology, biomanufacturing, brain-computer interfaces, and sixth-generation communication [1] Group 2: Examination Quality and Efficiency - The average examination period for invention patents has been reduced to 15 months, while trademark registration maintains an average examination period of 4 months, both of which are among the fastest internationally under the same examination system [1] - The revision of the Patent Examination Guidelines aims to enhance protection rules for new fields and new business models, further incentivizing industrial innovation [1] Group 3: Mechanisms for Utilization - The establishment of 129 national-level IP protection centers and rapid rights protection centers by the end of 2025 has significantly improved the efficiency of dispute resolution, maintaining a high first-instance settlement rate of 90% for civil IP cases [2] - The introduction of a green channel and the 2025 revised examination guidelines clarifies the protection boundaries for AI training data and biotechnology patents, providing stable institutional expectations for innovators [2] Group 4: Challenges and Future Directions - Despite advancements, challenges remain in the form of frequent infringement, insufficient protection strength, and difficulties in international coordination, particularly in emerging fields where professional value assessment institutions and standards are lacking [3] - Future efforts in IP protection for emerging fields should focus on institutional supply, intelligent governance, and international collaboration to build a protection system that aligns with high-level technological innovation [3] Group 5: International Collaboration - China aims to leverage the "Belt and Road" cooperation platform and the rapid examination network to transform its experiences in AI, data elements, and green energy into international rules and public service products, providing institutional support for enterprises going global [4]

Core Insights - The article highlights the growing significance of technology and innovation outside Silicon Valley, particularly in the context of the Web Summit held in Doha, Qatar, which attracted over 30,000 attendees, including startups and investors [6][10]. Group 1: Event Overview - The Web Summit in Doha gathered 30,274 participants, including 1,637 startups and 931 investors, showcasing a diverse range of technological innovations [6]. - The event emphasized the importance of connections and collaborations among global entrepreneurs, moving away from the traditional Silicon Valley narrative [7][8]. Group 2: Investment Trends - Middle Eastern investors, particularly the Qatar Investment Authority (QIA) with assets of approximately $580 billion, are showing a strong preference for localized collaborations that align with their strategic goals [10]. - The establishment of Qatar's national AI company, Qai, indicates a significant investment in AI infrastructure and systems, further highlighting the region's focus on technological advancement [12]. Group 3: Company Highlights - GenEditBio, a gene editing company founded by Zhu Tian, aims to address local healthcare needs in the Middle East, particularly genetic diseases prevalent due to regional customs [11]. - Bizlysis, led by Liu Xiaobin, is leveraging AI to enhance supply chain efficiency in Qatar, addressing vulnerabilities exposed by traditional shipping methods [15][18]. - Brainthink, a company specializing in non-invasive brain-computer interface technology, is attracting interest from Middle Eastern investors due to its innovative applications in mental health monitoring [22]. Group 4: Global Innovation Landscape - The article discusses how emerging markets are adopting and adapting innovations that have previously been seen in China, indicating a shift in the global technology narrative [25][30]. - Various startups from different countries are presenting solutions that mirror successful models from China, showcasing a trend of shared innovation across borders [26][31]. Group 5: Conclusion - The narrative presented at the Web Summit reflects a broader and more inclusive view of technological progress, where innovations from various regions are recognized and valued equally [35].