Financial Data and Key Metrics Changes - Quanterix reported total revenue of $40.2 million for Q3 2025, representing a 12% year-over-year increase [11] - The company ended the quarter with $138 million in cash, cash equivalents, marketable securities, and restricted cash [14][16] - Adjusted EBITDA was a loss of $11.9 million, compared to a loss of $5.5 million in the same quarter of the previous year [14] Business Line Data and Key Metrics Changes - Simoa contributed $23 million in revenue, reflecting a 36% organic revenue decline, while Spatial reported $17.2 million, down 9% year over year [11] - Consumable revenue totaled $18.8 million, with $12.3 million from Simoa and $6.5 million from Spatial [12] - Accelerator Lab revenue was $8 million, with $5 million from Simoa and $3 million from Spatial, showing a sequential increase of $1 million [12] Market Data and Key Metrics Changes - U.S. academic revenue declined approximately 30%, tracking the decline in academic grants, while pharma revenue declined 23% year over year [12] - Demand across the broader industry remains uneven, but signs of stabilization are noted, particularly in academic, government, and pharma markets [6] Company Strategy and Development Direction - The company is focused on integrating operations following the acquisition of Akoya, having realized $67 million of the targeted $85 million in synergies [5][8] - Significant investments are being made in Alzheimer's diagnostics and new assays across Simoa Spatial franchises, with approximately $27 million invested in R&D year to date [6][9] - The integration of Simoa and Spatial is expected to unlock new growth avenues, particularly in oncology and multimodal biomarker strategies [7][10] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving cash flow breakeven in 2026 and expects to finish the year with around $120 million in cash and no debt [6][9] - The company anticipates continued improvement in the operating environment, with a focus on capturing synergies and enhancing profitability [10][16] - Management remains cautious about the impact of the government shutdown on Q4 guidance, but believes risks have bottomed out [40] Other Important Information - The company is preparing for the launch of an early access program for Simoa ONE, which is expected to be a catalyst for future instrument growth in Alzheimer's diagnostics [9][67] - Diagnostics-related revenue was $2.4 million in the quarter, with expectations for stronger traction in 2026 based on established pricing recommendations [9][50] Q&A Session Summary Question: What is the outlook for Simoa consumables given the decline? - Management noted that while order volume was consistent, the order size was smaller due to a challenging academic grant environment, but expects smaller projects to scale in 2026 [20][22] Question: What are the plans for Q4 regarding integration and synergies? - Management confirmed that a single manufacturing team has been implemented and lab services are being combined, with expectations to capture remaining synergies in early 2026 [24][25] Question: How is the Akoya business expected to perform in Q4? - Management modeled a slight step down in Akoya's revenue for Q4 due to market uncertainty but noted strong execution in Q3 [28][29] Question: What is the competitive landscape and how is the company addressing it? - Management acknowledged competition in high sensitivity platforms but emphasized their unique position in the four to five marker space, which is expected to benefit from discovery progress [41][43] Question: What is the expected ramp-up for LucentAD in 2026? - Management indicated that established pricing will support stronger traction and growth in diagnostics revenue, with ongoing partnerships in Asia contributing positively [50][70]

Core Insights - 10x Genomics reported a revenue of $149 million for the quarter ended September 2025, reflecting a decrease of 1.8% year-over-year, while EPS improved to -$0.22 from -$0.30 in the previous year [1] - The revenue exceeded the Zacks Consensus Estimate of $142.39 million by 4.64%, and the EPS also surpassed the consensus estimate of -$0.27 by 18.52% [1] Revenue Breakdown - Services revenue was reported at $8.13 million, exceeding the average estimate of $7.86 million by analysts, marking a year-over-year increase of 27.1% [4] - Instruments revenue was $12 million, below the average estimate of $14.06 million, representing a significant decline of 37% year-over-year [4] - Chromium Instruments revenue was $4.93 million, slightly below the estimate of $5.36 million [4] - Consumables revenue from Chromium was reported at $92.52 million, surpassing the average estimate of $85.29 million [4] - Spatial Consumables revenue was $35.37 million, slightly above the average estimate of $35.06 million [4] - Total Consumables revenue reached $127.89 million, exceeding the average estimate of $120.35 million, with a year-over-year change of 1.3% [4] - Spatial Instruments revenue was reported at $7.07 million, below the average estimate of $8.71 million [4] Stock Performance - Over the past month, shares of 10x Genomics have returned +11.8%, significantly outperforming the Zacks S&P 500 composite, which saw a change of +1.3% [3] - The stock currently holds a Zacks Rank 1 (Strong Buy), indicating potential for outperformance in the near term [3]

Core Insights - 10x Genomics reported revenue of $172.91 million for the quarter ended June 2025, reflecting a year-over-year increase of 12.9% and surpassing the Zacks Consensus Estimate of $139.44 million by 24% [1] - The company achieved an EPS of $0.28, a significant improvement from -$0.32 in the same quarter last year, resulting in an EPS surprise of 180% compared to the consensus estimate of -$0.35 [1] Revenue Breakdown - Consumables revenue reached $122.19 million, slightly above the average estimate of $117.21 million, but showing a year-over-year decline of 1% [4] - Instruments revenue was reported at $14.5 million, below the average estimate of $14.9 million, marking a substantial year-over-year decrease of 39.2% [4] - Chromium instruments generated $5.73 million, slightly exceeding the estimated $5.6 million [4] - Services revenue amounted to $8.48 million, outperforming the estimate of $7.36 million, and reflecting a year-over-year increase of 43.9% [4] - Consumables from Chromium totaled $85.79 million, surpassing the estimate of $84.35 million [4] - Spatial consumables revenue was reported at $36.4 million, exceeding the average estimate of $32.86 million [4] - Spatial instruments revenue was $8.77 million, below the average estimate of $9.3 million [4] Stock Performance - Over the past month, shares of 10x Genomics have returned +4.6%, outperforming the Zacks S&P 500 composite's +1.2% change [3] - The stock currently holds a Zacks Rank 2 (Buy), indicating potential for outperformance in the near term [3]

Core Insights - Niantic, known for the popular mobile game Pokémon GO, has decided to sell its gaming business for $3.5 billion to Scopely and shift its focus to enterprise-level AI, rebranding itself as Niantic Spatial [3][4][11] - The company aims to leverage its extensive location data, accumulated from players walking over 30 billion miles, to develop AI models that analyze the real world and serve enterprise clients [4][6][19] Group 1: Strategic Shift - The CEO John Hanke emphasized that the restructuring allows both the gaming and AI divisions to pursue their respective futures more effectively [4][11] - Niantic's new platform, Spatial, offers AI mapping tools for businesses, enabling applications such as robot route planning and augmented reality glasses [4][6] - The decision to pivot to AI reflects the broader impact of generative AI trends in Silicon Valley, with the spatial computing market projected to grow from $110 billion in 2023 to $1.7 trillion by 2033 [6][7] Group 2: Financial Aspects - Niantic raised $250 million from existing investors to fund the new company, with the transaction expected to complete by the end of the month [7] - The gaming business, particularly Pokémon GO, has generated approximately $8 billion in revenue since its launch in 2016, with an estimated $770 million contribution to Niantic's projected $1 billion revenue in 2024 [8][11] - Despite the sale, Niantic will continue to provide augmented reality mapping services to Scopely, maintaining access to critical location data for AI model development [20][21] Group 3: Competitive Landscape - Niantic faces strong competition in the spatial AI sector from companies like Nvidia, which has launched the Omniverse platform for creating 3D digital twins [7] - The company has also encountered challenges in replicating the success of Pokémon GO, with previous titles like Harry Potter: Wizards Unite failing to achieve similar popularity [10][16] Group 4: Data Privacy and Ethical Considerations - The sale of the gaming business raised concerns regarding user data management, particularly due to Scopely's backing by the Saudi sovereign wealth fund [21] - Hanke reassured that data privacy regulations will be strictly followed, and user data will remain under the control of Niantic and Scopely [21] - Niantic has clarified that data collection for AI model training will only occur with user consent during specific actions, addressing player concerns about data usage [21]

Core Insights - 10x Genomics reported revenue of $154.88 million for the quarter ended March 2025, reflecting a year-over-year increase of 9.8% and exceeding the Zacks Consensus Estimate of $133.25 million by 16.24% [1] - The company posted an EPS of -$0.36, an improvement from -$0.50 in the same quarter last year, with a surprise of 20.00% compared to the consensus estimate of -$0.45 [1] Revenue Breakdown - Consumables revenue reached $115.36 million, slightly below the average estimate of $115.85 million, marking a year-over-year increase of 4.6% [4] - Instruments revenue was reported at $14.82 million, significantly lower than the average estimate of $17.30 million, representing a year-over-year decline of 41.8% [4] - Chromium instruments generated $5.91 million, compared to the estimated $6.46 million [4] - Services revenue was $7.65 million, exceeding the average estimate of $6.30 million, with a year-over-year increase of 46.7% [4] - Consumables from Chromium totaled $84.11 million, surpassing the average estimate of $82.93 million [4] - Spatial consumables revenue was $31.25 million, slightly below the average estimate of $32.91 million [4] - Spatial instruments revenue was $8.90 million, compared to the estimated $10.85 million [4] Stock Performance - Over the past month, shares of 10x Genomics have declined by 4.2%, while the Zacks S&P 500 composite increased by 11.3% [3] - The stock currently holds a Zacks Rank 3 (Hold), indicating expected performance in line with the broader market in the near term [3]