Group 1 - Johnson & Johnson is set to release its second-quarter earnings on July 16, with analysts estimating adjusted earnings of $2.68 per share and sales of $22.85 billion [1] - Investor focus will be on the updated 2025 guidance, the impact of tariffs and biosimilars, and the progress of the company's pipeline and recent product launches [1][3] - Bank of America Securities has updated its revenue estimates for Johnson & Johnson for 2025 and beyond ahead of the earnings release [2] Group 2 - Bank of America slightly increased its second-quarter 2025 revenue and EPS estimates by 1% due to improved foreign exchange rates, with similar modest increases projected for the later 2020s [4] - Despite the upward revisions, Bank of America maintains a Neutral rating and a price forecast of $61, considering the stock fairly valued [5] - Johnson & Johnson anticipates a $2 billion net headwind in 2025, affecting various assets while Xarelto is expected to benefit [6] Group 3 - CFO Joseph Wolk revised the estimated 2025 tariff impact down to $200 million from $400 million, with the majority expected in the second half of the year [7] - A federal court sided with the U.S. Department of Health and Human Services, rejecting Johnson & Johnson's attempt to alter its participation in the 340B Drug Pricing Program [7][8]

Key Takeaways MRK faces major headwinds as Keytruda, its top seller, nears the loss of exclusivity in 2028. Gardasil sales dropped 40% in Q1 2025 due to weak China demand, despite strength in other regions. MRK expects IRA's Medicare drug pricing to impact Januvia in 2026 and Keytruda starting in 2028.Merck (MRK) is expected to face several hurdles over the next few years that could affect its long-term growth trajectory, starting with the anticipated loss of exclusivity of its blockbuster PD-L1 inhibitor ...

Key Takeaways JNJ expects 2025 to be a catalyst year, with accelerating growth in the second half of the decade. PFE faces declining COVID revenues and upcoming patent expirations for several key drugs. JNJ forecasts 5-7% annual growth in Innovative Medicine from 2025 to 2030Johnson & Johnson (JNJ) and Pfizer (PFE) rank among the world’s largest pharmaceutical companies, each with broad and diversified healthcare portfolios. J&J operates primarily through its pharmaceuticals and medical devices segments. ...

Core Insights - AbbVie has effectively managed the loss of exclusivity for Humira by launching two new immunology drugs, Skyrizi and Rinvoq, with significant sales expected in the upcoming quarterly report [1][3][8] Group 1: Drug Performance and Sales Expectations - Skyrizi and Rinvoq have been launched across major indications previously covered by Humira, including a new indication for atopic dermatitis, showing strong performance particularly in inflammatory bowel disease (IBD) [2] - AbbVie anticipates combined sales of $6 billion for Skyrizi and Rinvoq in the second quarter, with individual estimates of $4 billion for Skyrizi and $2 billion for Rinvoq [3][8] Group 2: Expansion in Other Therapeutic Areas - AbbVie is also expanding its oncology and neuroscience portfolios, adding new therapies such as Epkinly, Elahere, and Emrelis, bringing its total oncology therapies to five [4] - The neuroscience segment has seen growth driven by increased uptake of migraine treatments, Ubrelvy and Qulipta [4] Group 3: Competitive Landscape - The immunology market is highly competitive, with key players like Johnson & Johnson and Eli Lilly also expanding their portfolios. Johnson & Johnson is focusing on Tremfya after Stelara lost patent exclusivity [5] - Eli Lilly has recently received FDA approval for Omvoh, marking its entry into the IBD market, which enhances its immunology offerings [6] Group 4: Valuation and Market Performance - AbbVie shares have outperformed the industry year to date, trading at a price/earnings (P/E) ratio of 14.21, slightly below the industry average of 15.01 [7][10] - The bottom-line estimate for AbbVie in 2025 remains at $12.28, with a slight increase in the 2026 estimate from $14.05 to $14.06 [11]

Key Takeaways PFE expects steady 2025 COVID sales but anticipates major LOE losses and IRA headwinds in the future. Medicare Part D changes may cut into sales of key PFE drugs like Vyndaqel, Ibrance, Xtandi and Xeljanz. PFE trades at 7.82x forward earnings, below industry average, with EPS estimates rising for 2025 and 2026.Pfizer (PFE) is likely to encounter several headwinds in the next couple of years that can hurt its sales and profits, the first being declining sales of COVID products, Comirnaty and ...

Johnson & Johnson (JNJ) FY Conference June 11, 2025 03:20 PM ET Speaker0 America. And, we are front and center wanting to work with the administration. And there's areas that I would say organizationally and and from an industry perspective, think we could have a substantial impact. And and some of it, we're encouraged by the administration recognizes it. Some of them, the middlemen, focusing on the PBM reform, 340B reform, areas where we can bring the cost and drive it down to the patient so they can actua ...

TREMFYA ® demonstrated two and a half times greater ability to inhibit joint structural damage versus placebo in the Phase 3b APEX studyMore than 40% of TREMFYA®-treated patients across both dose groups achieved ACR50 at Week 24Improvement in both joint and skin symptoms reinforce TREMFYA® as a first-line treatment option with a proven safety profile for adults with active psoriatic arthritis BARCELONA, June 11, 2025 /PRNewswire/ -- Johnson & Johnson (NYSE: JNJ) today announced findings from the Phase 3b AP ...

Core Insights - AbbVie anticipates a return to strong revenue growth in 2025, following the loss of U.S. exclusivity for Humira, which saw a nearly 50% year-over-year sales decline to $1.12 billion in Q1 2025 [1][7] - The ex-Humira platform experienced over 21% year-over-year growth in Q1 2025, driven by the performance of newer immunology drugs, Skyrizi and Rinvoq [2][7] - AbbVie raised its sales guidance by approximately $900 million, now targeting $24.7 billion in combined sales from Skyrizi and Rinvoq for 2025 [3][7] Ex-Humira Growth - Skyrizi and Rinvoq are leading the growth in AbbVie's ex-Humira revenue, particularly in the inflammatory bowel disease (IBD) market, which includes ulcerative colitis (UC) and Crohn's disease (CD) [2][3] - Strong market growth and the potential for new indications for Rinvoq are expected to further drive sales [3] Competitive Landscape - The immunology market is highly competitive, with Johnson & Johnson's Stelara and Tremfya as key competitors, especially after Stelara lost U.S. exclusivity [4] - Eli Lilly is also expanding its immunology portfolio with the recent FDA approval of Omvoh for UC and CD indications [5] Valuation and Performance - AbbVie shares have outperformed the industry year-to-date, trading at a price/earnings (P/E) ratio of 14.48, slightly below the industry average of 15.12 [6][9] - The Zacks Consensus Estimate for 2025 earnings has slightly decreased from $12.30 to $12.28 per share, while the estimate for 2026 has increased from $13.97 to $14.05 [10]

Spyre Therapeutics Inc (SYRE) FY Conference June 09, 2025 09:20 AM ET Speaker0 Thank you for joining us. I'm Paul Choi, and I cover biotechnology here at the firm. It's our pleasure to welcome Spire, and we have Cameron here on on stage with us. Maybe to to kick it off, Cameron, can just give us a brief overview of Spire and just sort of the key programs and technologies under pending pending the company? Yeah. Speaker1 Of course. And so and thanks for having us. It's a great event as always. So the backgro ...

NEW YORK, June 04, 2025 (GLOBE NEWSWIRE) -- Royalty Pharma plc (Nasdaq: RPRX) today announced that it will participate in a fireside chat at the Goldman Sachs 46th Annual Global Healthcare Conference on Tuesday, June 10, 2025 at 2:00 p.m. ET. The webcast will be accessible from Royalty Pharma’s “Events” page at https://www.royaltypharma.com/investors/events/. The webcast will also be archived for a minimum of thirty days. About Royalty Pharma Founded in 1996, Royalty Pharma is the largest buyer of biopharm ...