Johnson & Johnson (JNJ) Q2 2025 Earnings Call July 16, 2025 08:30 AM ET Company Participants Darren Snellgrove - VP - IR Joaquin Duato - CEO, Chairman & Director Joseph Wolk - EVP & CFO Chris Schott - Managing Director Jennifer Taubert - EVP & Worldwide Chairman - Innovative Medicine Tim Schmid - EVP & Worldwide Chairman - MedTech John Reed - EVP - Innovative Medicine & R&D Alexandria Hammond - Director - Head of Therapeutics Conference Call Participants Terence Flynn - Equity Research Analyst Lawrence Bieg ...

Financial Data and Key Metrics Changes - In Q2 2025, worldwide sales reached $23.7 billion, reflecting a 4.6% increase despite a headwind from Stellara [23][24] - Net earnings for the quarter were $5.5 billion, with diluted earnings per share of $2.29, compared to $1.93 a year ago [24] - Adjusted net earnings were $6.7 billion, with adjusted diluted earnings per share of $2.77, representing a decrease of 2.1% year-over-year [25][32] Business Line Data and Key Metrics Changes - Innovative Medicine reported worldwide sales of $15.2 billion, increasing by 3.8% despite an 11.7% headwind from Stellara [25][26] - MedTech achieved worldwide sales of $8.5 billion, growing by 6.1%, with strong performance in cardiovascular, surgery, and vision [29][30] - In oncology, DARZALEX grew by 21.5%, while CARVICTI saw over 100% growth [26][27] - Tremfya in immunology grew by 30.1%, while Stellara declined by 43.2% due to biosimilar competition [28] Market Data and Key Metrics Changes - U.S. sales growth was 7.6%, while international sales saw a decline of 1.6% due to Stellara biosimilars and COVID-19 vaccine impacts [25][26] - Cardiovascular segment delivered over 22% operational sales growth, driven by new product performance [17][29] - Surgical vision grew by 8.9%, supported by strong performance in contact lenses and intraocular lenses [21][30] Company Strategy and Development Direction - The company aims to become the number one oncology company by 2030, targeting over $50 billion in sales [10][11] - Focus areas for growth include oncology, immunology, neuroscience, cardiovascular, surgery, and vision, with a commitment to innovation [8][12] - The company plans to launch several new products and expand its pipeline, including TAR200 for bladder cancer and icotrokinra for psoriasis [47][48] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving and potentially exceeding growth targets for 2025, driven by strong performance in both Innovative Medicine and MedTech [36][39] - The company anticipates an acceleration in operational sales growth in the second half of the year, supported by new product launches and market share gains [40][46] - Management highlighted the importance of navigating external challenges, including tariffs and competition, while maintaining a focus on innovation and market leadership [88] Other Important Information - The company ended Q2 with $19 billion in cash and marketable securities and $51 billion in debt, resulting in a net debt position of $32 billion [38] - The effective tax rate for the quarter was 14.7%, down from 18.5% in the previous year [33] - The company is committed to investing $55 billion in the U.S. over the next four years, driven by favorable tax policies [39] Q&A Session Summary Question: Drivers of upside to guidance for the year - Management indicated that both Innovative Medicine and MedTech contributed to strong performance, with notable growth in oncology and cardiovascular segments [52][53] Question: Oncology target of $50 billion by the end of the decade - Management expressed confidence in achieving this target, citing strong growth in multiple myeloma and the potential of TAR200 for bladder cancer [68][71] Question: Guidance for operational growth and operating margin improvement - Management expects 2026 to show better growth rates than 2025, with ongoing efforts to improve operating margins [81][83] Question: Impact of pharma tariffs and manufacturing capacity - Management acknowledged uncertainty regarding tariffs but emphasized ongoing investments in U.S. manufacturing and job creation [88]

This morning we are talking to GameStop CEO Ryan Cohen, uh, who's a little bit behind some of this. Ryan, uh, great to see you. It's been a while.U, what is going I have about a million questions about what's going with GameStop and your investments and everything else, but let's start with the stapler. Um, it's up to what, $250,000 right now. Yes.So what. So we had our store in Staten Island on launch day and the store manager uh took the stapler and stapled it into the switch. So, we damaged the switch.We ...

2025年7月2日，NMPA公布了创新医疗器械特别审查申请审查结果公示（2025年第6号），有 14款产品 进 入创新通道。其中包括， 施爱德（厦门）医疗器材有限公司 申请的 一次性带可吸收钉电动痔吻合器 。 # 研发背景 痔疮 是全球常见的肛肠疾病，特别是在中国，随着生活方式变化（如久坐、饮食习惯等），痔疮发病率逐年 上升。根据统计，中国肛肠疾病患者中， 痔疮占比约50%-60%，其中中重度痔疮（III-IV度）常需手术治疗 。 传统痔疮手术（如外剥内扎术）创伤大、恢复慢、术后疼痛明显， 微创技术（如PPH）因创伤小、恢复快、 并发症少 而受到患者和医生的青睐。传统痔吻合器多采用不可吸收钉，术后需二次手术取出，增加了患者的 痛苦和感染风险。 电动吻合器 通过精准切割和缝合，显著提升手术效率。 可吸收钉（如聚乳酸、聚乙醇酸等材料） 的发展，解 决了传统金属钉需二次手术取出的问题，降低了术后异物感及感染风险，推动了吻合器技术的革新。 电动驱动技术、生物材料技术及精密制造技术的进步，使得一次性电动吻合器能够实现更高的精度和安全性。 # 产品介绍 施爱德（厦门）医疗器材有限公司研发的一次性带可吸收钉电动痔吻合器，专 ...

Core Insights - The demand for gynecology surgical instruments is increasing due to the rising prevalence of gynecological diseases and government investments in women's health, with a projected market growth rate of 8.26% CAGR from 2024 to 2032 [1] - Hologic's GYN Surgical business has shown a 7.6% CAGR over the past decade, driven by the MyoSure suite and the Fluent fluid management system [1][8] - The launch of the Fluent Pro system in late 2024 is expected to enhance MyoSure's performance and user experience, contributing positively to Hologic's Surgical performance [2] Market Position and Growth - Hologic's International Surgical segment remains the leading revenue driver, supported by investments in market development for minimally invasive GYN products [2] - Legacy NovaSure devices are gaining traction in Europe, despite declining volumes in the U.S., indicating significant expansion opportunities in international markets [3] - Inorganic investments, such as the acquisitions of Acessa Health and Gynesonics, have strengthened Hologic's product offerings and global market reach [4] Competitive Landscape - Hologic faces competition from major companies like Johnson & Johnson and Medtronic in the GYN Surgical space [5] - Johnson & Johnson's MedTech segment reported $8 billion in sales for Q1 2025, with a 4.1% year-over-year growth [6] - Medtronic's Medical Surgical Portfolio saw a 2% increase in Q4 2025, with expectations for improved growth as it expands its robotic platform [6] Financial Performance - Hologic's stock has declined by 8.7% year-to-date, slightly better than the industry's 9.1% decline [7] - The company is trading at a forward 12-month earnings multiple of 14.85, which is lower than the industry average of 28.39 [9] - Consensus estimates for Hologic's fiscal 2025 and 2026 earnings show a bearish trend, with current estimates remaining stable [10][11]

Core Insights - Intuitive Surgical (ISRG) has developed a comprehensive portfolio focused on minimally invasive care, primarily through its da Vinci robotic surgical systems, which enhance precision and control in complex procedures [1][3] - The company is expanding its offerings with the Ion endoluminal system for early-stage lung cancer diagnosis, diversifying its revenue streams and enhancing its diagnostic capabilities [2] - Intuitive Surgical supports its hardware ecosystem with digital tools and training resources to improve surgeon proficiency and optimize hospital workflows [3] Company Overview - The da Vinci systems include multi-port platforms like Xi and X, as well as the next-generation da Vinci 5, and the single-port da Vinci SP platform for narrow-access procedures [1] - The Ion system is gaining commercial traction, contributing to revenue diversification and expanding ISRG's presence in the diagnostic market [2] - The company has performed over 12 million da Vinci procedures globally and has more than 10,000 systems installed, solidifying its leadership in minimally invasive care [3] Competitive Landscape - Johnson & Johnson (JNJ) is heavily investing in its minimally invasive surgery portfolio through its MedTech division, with products like the VELYS Robotic-Assisted Solution and the Ottava soft-tissue robotic system [4] - Edwards Lifesciences (EW) is a leader in structural heart therapies, particularly with its transcatheter aortic valve replacement (TAVR) solutions, and is expanding into mitral and tricuspid segments [5] Financial Performance - ISRG shares have decreased by 1.9% year-to-date, while the industry has seen an 11% decline [6] - The company trades at a forward price-to-sales ratio of 18.02, which is above the industry average, and carries a Value Score of D [8] - The Zacks Consensus Estimate for ISRG's 2025 earnings suggests a 6.8% year-over-year increase [9] Earnings Estimates - The Zacks Consensus Estimate for the current quarter (6/2025) is $1.92, with estimates for the next quarter (9/2025) at $1.96, and for the current year (12/2025) at $7.84 [10] - Year-over-year growth estimates for the current year and next year are 6.81% and 15.46%, respectively [10]

Core Viewpoint - Intuitive Surgical (ISRG) has shown a recovery in its stock price after a significant decline, driven by strong fundamentals and a favorable trade environment despite ongoing tariff risks [1][2]. Financial Performance and Revenue Growth - ISRG reported first-quarter 2025 revenues of $2.25 billion, reflecting a 19.2% year-over-year increase, with 85% of total earnings coming from consistent, recurring revenues [3]. - The company achieved a 20% growth in earnings per share (EPS), reaching $1.81, and maintained an operating margin of 34.1%, although a decline in operating margin is anticipated for 2025 due to increased depreciation and a higher mix of lower-margin products [3]. Market Performance - Despite a recent drop in share price, ISRG's shares have increased by 8.4%, outperforming the Zacks Medical - Instruments industry's decline of 6.9% year to date [4]. Procedure Volume and Market Expansion - Revenue growth in the first quarter was driven by increased da Vinci procedure volume and strong growth in Ion and SP procedures, with the company raising procedure prices to combat inflation [7]. - The adoption of the da Vinci 5 system is expected to boost revenues, with plans for a broad launch in the second half of the year, although challenges in markets like Germany, the U.K., and Japan may slow adoption [8]. - Recent FDA clearance for the da Vinci Single Port surgical system is anticipated to further enhance system revenues [9]. Competitive Challenges and Market Headwinds - ISRG expects a gross margin headwind of 170 basis points in 2025 due to global tariffs, particularly from U.S.-China trade tensions and European retaliatory tariffs [10]. - The company faces increasing competition in robotic-assisted surgery from major players like Johnson & Johnson and Medtronic, which are investing heavily in this space [12]. Valuation and Investment Outlook - ISRG's stock is trading at a premium compared to the industry, raising concerns about valuation, although it is below its five-year median [16]. - The company holds a Zacks Rank 3 (Hold), with Style Scores indicating a Value Score of D and a Growth Score of C, suggesting caution for new positions while indicating potential upside based on strong fundamentals [17][18].

Core Insights - The Titan SGS™ Stapler is associated with significantly lower rates of postoperative gastroesophageal reflux disease (GERD) and shorter hospital stays compared to traditional multi-fire staplers in robotic-assisted laparoscopic sleeve gastrectomy (LSG) procedures [1][3][4] - A retrospective analysis of 257 patients showed that at one year post-procedure, 7.1% of patients using the Titan SGS™ Stapler reported GERD, compared to 26.4% in the multi-fire cohort [3][4] - The study highlights the importance of consistent surgical techniques in achieving better patient outcomes, particularly in reducing GERD incidence [2][3] Company Overview - Teleflex Incorporated is a leading global provider of medical technologies, focusing on improving health and quality of life through innovative solutions [5][6] - The Titan SGS™ Stapler is the first single-fire surgical stapler specifically designed for sleeve gastrectomy pouch creation, featuring a 23cm staple line for improved surgical outcomes [3][4] - The company aims to enhance the adoption of bariatric surgery by addressing common postoperative complications such as GERD [3][5]

Investment Rating - The report maintains a "Buy" rating for Weigao, AK Medical, and AngelAlign, while holding a "Neutral" rating for Jinxin and Tigermed [2][3][13]. Core Insights - The report indicates a cautious optimism regarding the recovery of surgical volumes in 2025, with expectations of manageable impacts from recent regulatory changes and tariff adjustments [1][4]. - The focus is shifting towards internal operational management and shareholder returns, with companies emphasizing cash flow management and reducing capital expenditures [8][11]. Summary by Sections Surgical Volume and Regulatory Environment - Surgical volume is expected to trend positively in 2025, with many companies reporting improved sentiment at the start of the year [4]. - The impact of the Value-Based Pricing (VBP) is seen as manageable, with major players focusing on market share gains [4][7]. Company-Specific Developments - Weigao anticipates a revenue growth of 10-15% year-on-year in FY25, driven by new product ramp-ups [9]. - AK Medical's market share in Tier 1 hospitals has increased significantly, and the company expects continued growth in overseas markets [4][9]. - AngelAlign is focusing on overseas expansion, particularly in Europe, with a projected 50% year-on-year increase in overseas case volumes [9][19]. Financial Guidance and Earnings Revisions - The report revises sales estimates downwards for several companies, with average changes of -1.6% to -2.2% for 2025-2027 and earnings estimates down by -13.3% to -16.7% [1][14]. - Gushengtang expects revenue growth to exceed 25% year-on-year in FY25, while Jinxin did not provide specific revenue guidance due to uncertainties [8][19]. Target Price Changes - Target prices have been adjusted for several companies, with Hygeia's target price set at HK$27.60, AngelAlign at HK$76.20, and Gushengtang at HK$46.00 [13][17][18].

Teleflex Incorporated (NYSE:TFX) Q4 2024 Earnings Conference Call February 27, 2025 8:00 AM ET Company Participants Lawrence Keusch - VP-IR & Strategy Development Liam Kelly - Chairman, President & CEO Thomas Powell - EVP & CFO John Deren - Corporate VP and Chief Accounting Officer Conference Call Participants Patrick Wood - Morgan Stanley Matthew O'Brien - Piper Sandler Jayson Bedford - Raymond James Shagun Singh - RBC Larry Biegelsen - Wells Fargo Anthony Petrone - Mizuho Group Richard Newitter - Truist S ...