Financial Performance & Guidance - Q3 2025 net product sales grew to $64.1 million, a 65% increase compared to Q3 2024[10, 158] - Rigel increased its 2025 net product sales guidance to $225 million - $230 million, up from $210 million - $220 million[12] - Rigel anticipates 2025 total revenue of ~$285 million to $290 million[162] - Cash, cash equivalents & short-term investments as of September 30, 2025, was $137.1 million compared to $77.3 million as of December 31, 2024[162] Product Performance - TAVALISSE Q3 2025 net product sales reached $44.7 million, a 70% increase compared to Q3 2024[16] - GAVRETO Q3 2025 net product sales reached $11.1 million, a 56% increase compared to Q3 2024[16] - REZLIDHIA Q3 2025 net product sales reached $8.3 million, a 50% increase compared to Q3 2024[16] R289 Clinical Development - In a Phase 1b study in R/R lower-risk MDS, 33% (6/18) of evaluable transfusion-dependent patients receiving ≥500 mg QD achieved RBC-TI >8 weeks[124, 131] - The median duration of RBC-TI was 22.9 weeks (9 - 104.3)[124] Strategic Collaborations - Contract revenues from collaborations were $5.4 million in Q3 2025[158]

Pociredir 20mg Cohort Data Highlights - The 20 mg cohort data raises the bar on Pociredir's best-in-class potential for treating sickle cell disease[14, 17] - At Week 6, the 20 mg cohort (n=12) showed a 99% mean absolute increase in HbF[17] - 58% of patients (7/12) in the 20 mg cohort achieved ≥20% HbF at their latest study visit[17] - In the 20 mg cohort, the six patients who completed the 12-week treatment period achieved >375-fold induction of HbF[17] Clinical Improvements - The study observed a 28% reduction in Lactate Dehydrogenase (LDH) and a 37% reduction in indirect bilirubin, indicating consistent reductions in markers of hemolysis with the 20 mg dose[71, 72] - There was a 31% reduction in Mean Absolute Reticulocyte Count (ARC) and a 22% reduction in Mean Red Cell Distribution Width (RDW-CV) with the 20 mg dose, indicating consistent improvements in red blood cell morphology and erythropoiesis[75] - Mean hemoglobin increased from 73 g/dL to 81 g/dL in the 20 mg cohort[81] - 67% of patients (8/12) reported no vaso-occlusive crises (VOCs) during the 12-week treatment period[86] Safety and Tolerability - Pociredir at 20 mg was generally well-tolerated, with 23% of patients (3/13) reporting treatment-related adverse events[90] - There were no serious treatment-related adverse events in the 20 mg cohort[90]

Acquisition Overview - Virtus Investment Partners will acquire a 56% majority interest in Keystone National Group for $200 million in cash at closing[13] - Up to $170 million in deferred consideration, including earnout payments, may be paid based on future revenue targets[13] - Management will retain a 44% stake, with Virtus increasing ownership to 75% through staged equity purchases in years 3-6[13] Keystone National Group Highlights - Keystone manages $2.5 billion in assets under management (AUM) across four core strategies[8, 11] - Keystone's flagship $2.0 billion tender offer fund (KPIF) is available in the RIA market[8, 11] - Keystone has invested over $6 billion of capital in more than 750 transactions since its founding in 2006[11] - Keystone's Real Estate Private Credit AUM is ~$400 million and Real Estate Equity AUM is ~$100 million[12] Financial Impact - The transaction is expected to increase Virtus' operating margin by approximately 200 basis points[13] - The estimated contribution to 2026 EPS, as adjusted, is approximately $1.50[13] - Intangible assets are expected to create annual tax savings of approximately $5 million per year[13] Market Context - Non-bank financing represents $1.9 trillion of the ~$5.5 trillion US Specialty Finance market[20] - Private credit accounts for $200-300 billion of the Specialty Finance market[20]

Financial Performance (3Q 2025) - Revenues reached $96.9 million[10], with an operating income of $30.6 million[10] and a net income of $15.1 million[10] - Adjusted EBITDA stood at $61.6 million[10] - A cash distribution of $0.026 per common unit was paid in November 2025[10, 18] Key Transactions & Refinancing - Daqing Knutsen was purchased for a net cash cost of $24.8 million[12], with KNOT guaranteeing the hire rate until July 2032[12, 22] - A common unit buyback program was concluded in October, with 384,739 common units purchased for $3.03 million, averaging $7.87 per unit[13, 28] - The Synnøve Knutsen loan was refinanced with a new $71.1 million senior secured term loan facility[24] - Refinancing of the Tove Knutsen was completed, generating $32 million of net proceeds[16] Contractual Agreements & Fleet Utilization - Fleet operated with 99.9% utilization, or 96.5% overall including the drydocking of the Tove Knutsen[10, 74] - The term of the current time charter for the Bodil Knutsen was extended to a fixed term ending in March 2029, followed by two charterer's options each of one year[17] - The term of the current time charter for the Hilda Knutsen was extended by 3 months firm (to June 2026) plus a further 9 months at the company's option (to March 2027)[15] - A time charter for the Fortaleza Knutsen was executed with KNOT, to commence Q2 2026 for a fixed period of one year plus two charterer's options each for one additional year[27] Strategic Developments - KNOT made an unsolicited non-binding offer to purchase all publicly held common units of the Partnership for $10 in cash per common unit[9, 25] - Contractual backlog expanded to $939.5 million of fixed contracts averaging 2.6 years, with charterers' options averaging a further 4.2 years[32, 54]

Financial Performance - Q3 2025 - Net sales increased by 9%, driven by growth across Victoria's Secret, PINK, and Beauty[4] - International net sales surged by 34%[4] - Adjusted gross margin improved by 170 basis points to 365%[4,7] - Adjusted operating income reached $0 million, exceeding the guidance of an adjusted operating loss of ($35 million) - ($55 million)[4] - Adjusted EPS was reported at ($027), surpassing the guidance of ($055) - ($075)[6] Financial Performance - Year-to-Date 2025 - Net sales increased by 4% to $42836 million[9] - Operating income increased by 18% to $868 million[9] - Net income attributable to Victoria's Secret & Co increased by 1036% to $125 million[9] - Net income per diluted share attributable to Victoria's Secret & Co increased by 1400% to $015[9] Outlook - The company anticipates full-year net sales to be approximately $645 billion to $648 billion[14] - The company anticipates full-year adjusted operating income to be approximately $350 million to $375 million[14]

Deal Overview - Netflix will acquire Warner Bros for $27.75 per share, consisting of $23.25 in cash and $4.50 in Netflix stock per WBD share[25] - The total equity value of the deal is approximately $72 billion, with an enterprise value of $82.7 billion including Warner Bros' net debt of $10.7 billion[26] - The deal is expected to close in 12-18 months, subject to Warner Bros Discovery shareholder and regulatory approvals[25] Financial Highlights & Funding - The acquisition will be funded through $10.3 billion cash on hand, $50 billion in new debt financing, and $11.7 billion in equity consideration[28] - Netflix anticipates at least $2-3 billion of run-rate cost savings by year three and expects the transaction to be accretive to GAAP EPS by the second full year[32] - Warner Bros CY26E EBITDA is projected to be $5.8 billion, including $2.5 billion in run-rate synergies[28] Strategic Rationale - The acquisition combines Netflix's streaming service with Warner Bros' film and TV library and franchises[8, 15] - Netflix expects to maintain Warner Bros' current businesses, including theatrical releases and HBO Max & HBO operations[13, 14] - Netflix anticipates attracting and retaining more subscribers, driving more engagement, and generating incremental revenue and operating income[24]

Strategy and Targets - Swiss Re aims for a Group net income of USD 4.5 billion in 2026[4] - Swiss Re plans to initiate a sustainable annual share buyback of USD 0.5 billion starting in 2026[4] - The company is on track to reduce its operating cost run-rate by approximately USD 300 million by 2027[4, 13, 100] Business Unit Performance and Targets - L&H Reinsurance has increased its net income target to USD 1.7 billion for 2026[4, 95] - Corporate Solutions has maintained an average quarterly combined ratio of 90.6% since 2021[77] - P&C Reinsurance has increased loss assumptions by +10% since 2022[80] Data, Tech & AI - Swiss Re has a data platform with approximately 11,500 users across the Group[49] - The company's data corpus includes 8 million submissions, 24 million contracts, 44 million claims, and 17 million accounting documents[51] Capital Management - The Group SST ratio was 268% as of October 1, 2025[9] - Swiss Re expects to generate a dividend per share growth of ≥7% for the FY 2024-2026 period[74, 111]

Mines Outlook - In 2026, the first full year will include Somincor and Zinkgruvan operations[6] - Higher grades are expected in open pits[6] - Increased milled volume is anticipated at Aitik, Garpenberg, the Boliden Area, and Tara mines[6] - Potential cost increases of EUR 20-30 million are expected annually at Kevitsa[6] - Milled volume is expected to be stable at approximately 4.5 Mtonnes in coming years for Somincor[11] - Milled volume is expected to be stable at approximately 1.5 Mtonnes in coming years for Zinkgruvan[14] Smelters Outlook - Increased zinc and precious metal production is expected in Odda[6] - The Odda expansion is expected to increase annual capacity by 150 ktonnes of zinc and 45 ktonnes of leach product, improving annual EBITDA by approximately EUR 150 million at full production[18] - The ramp-up of the new tankhouse in Rönnskär is planned for H2 2026, with an annual copper cathode capacity of 230 ktonnes and an expected annual EBITDA increase of approximately SEK 1.2 billion when completed[19, 20] - Planned maintenance shutdowns at smelters are estimated to impact operating profit by SEK -450 million for the full year 2026[6, 21] Capital Expenditure - Group capital expenditure (capex) is projected to be SEK 15 billion, including mine sustaining capex of SEK 6.5 billion[6]

Financial Highlights - Q3FY26 total revenue reached $249 million[7] - Q3FY26 saw a YoY revenue growth of 25%[7] - Q3FY26 GTV was $22 billion, representing a YoY growth of 22%[7] - The company achieved a Q3FY26 non-GAAP operating margin of 8.6%[7] - Q3FY26 non-GAAP platform gross margin stood at 80.2%[7] - The net dollar retention rate for Q3FY26 exceeded 110%[7] Market Opportunity - The company addresses approximately $650 billion of the trades industry spend[20] - The total addressable market (TAM) is estimated to be over $1.5 trillion[21] - Potential revenue with full platform deployment is estimated at ~$13 billion[24] Customer Base - The company has approximately 9,500 active customers[41] - Over 1,000 customers generate >$100K in annualized billings, accounting for >50% of total annualized billings[41]

Financial Performance - Rubrik's Subscription ARR reached $1347 million, demonstrating a 34% year-over-year growth[11] - Cloud ARR within the Subscription ARR reached $1175 million, showing a 53% year-over-year growth[43] - The company maintains a high Average Subscription Dollar-Based Net Retention Rate (NRR) of over 120%[33] - Rubrik's Non-GAAP Gross Margin stands at 83%[33] - The company anticipates revenue growth on a reported basis will lag Subscription ARR growth by a few percentage points in FY27, primarily due to headwinds from material rights[82] Customer Growth - The number of customers with over $100,000 in Subscription ARR has increased to 2638[33] Product and Strategy - Rubrik is focusing on Cyber Resilience and AI transformation with its platform[8] - The company is emphasizing a Code to Cloud Cyber Resilience Platform approach to eliminate multi-cloud complexity[17] - Rubrik is expanding its offerings in Identity Resilience to secure identity infrastructure[18] Future Outlook - The company projects Subscription ARR for FY2026 to be between $1439 million and $1443 million[79] - Rubrik expects a total contribution of approximately $68 million in non-recurring revenue related to material rights in FY26[82]