Recursion Pharmaceuticals (RXRX) Q1 2025 Earnings Call May 05, 2025 08:00 AM ET Company Participants Chris Gibson - Co-Founder & CEONajat Khan - Chief R&D Officer, Chief Commercial Officer and DirectorBen Taylor - CFO & President Recursion UK Chris Gibson Hi, everybody. My name is Chris Gibson, cofounder and CEO of Recursion, and I'm delighted to welcome you to our learnings call this morning. We're gonna go ahead and get started. Perfect. So, of course, important to note that we're gonna be providing forwa ...

Recursion Pharmaceuticals (RXRX) Q1 2025 Earnings Call May 05, 2025 08:00 AM ET Company Participants Chris Gibson - Co-Founder & CEONajat Khan - Chief R&D Officer, Chief Commercial Officer and DirectorBen Taylor - CFO & President Recursion UK Chris Gibson Hi, everybody. My name is Chris Gibson, cofounder and CEO of Recursion, and I'm delighted to welcome you to our learnings call this morning. We're gonna go ahead and get started. Perfect. So, of course, important to note that we're gonna be providing forwa ...

Financial Data and Key Metrics Changes - For Q1 2025, the company achieved revenue of $19.5 million, an 11% increase from $17.6 million in Q1 2024 [4][11] - Gross profit margin was reported at 76.1%, consistent with Q1 2024 [12] - GAAP diluted earnings per share increased by 16% to $0.37 from $0.32 in Q1 2024 [13] - Non-GAAP adjusted net income was $5.3 million or $0.42 per diluted share, up 17% from $4.6 million or $0.36 per diluted share in Q1 2024 [14] Business Line Data and Key Metrics Changes - Revenue from IV infusion pump systems grew 16% to $6 million, while disposable revenue increased 23% to $4.9 million [11][12] - Patient vital signs monitoring systems revenue remained steady at $6.5 million [12] - Domestic sales accounted for 82% of total revenue, up from 76% in Q1 2024, with domestic revenue increasing 19% to $16 million [12] Market Data and Key Metrics Changes - International sales declined 15% to $3.5 million [12] - Device revenue increased 9% to $13 million, driven by pump revenue and FMD systems [12] Company Strategy and Development Direction - The company is focused on increasing monitoring sales in 2025, anticipating a decline in pump revenues later in the year [21] - The new 3,870 MRIV pump is expected to be a revenue driver in 2026, with clearance anticipated in mid-2025 [9][10] - The company is nearing completion of a new facility, with full operations expected by July 2025 [10] Management's Comments on Operating Environment and Future Outlook - Management remains optimistic about the impact of tariffs, noting that only 3% of revenue is connected to high tariff sources [6][7] - The FDA's responsiveness has been positive, with ongoing interactions indicating progress towards device clearance [25][27] - The company expects Q2 2025 revenue guidance of $19.7 million to $19.9 million, reiterating full-year revenue guidance of $78 million to $82 million [10] Other Important Information - Operating expenses were $9.4 million, or 48% of revenue, down from 49% in Q1 2024 [12] - Cash flow from operations was $4.3 million, up 10% from $3.9 million in Q1 2024 [14] Q&A Session Summary Question: Any anomalies in disposable revenue growth? - Management indicated that some backlog was worked down in Q1, contributing to the growth, but expects future growth to align with capital growth [17][18] Question: Confidence in monitoring sales recovery? - Management emphasized efforts to boost monitoring sales through adjusted compensation structures, with strong bookings already seen in Q2 [20][22] Question: Status of FDA interactions and clearance timeline? - Management noted ongoing interactive questions from the FDA, suggesting a positive sign, with expectations for clarity in the next three to four weeks [24][27]

Financial Data and Key Metrics Changes - The company reported Q1 revenue of $1,450 million and non-GAAP earnings per share of $0.55, both exceeding the midpoint of guidance, with a non-GAAP gross margin of 40% [5][16] - Free cash flow increased by 72% year over year to $455 million, representing 31% of revenue [24][16] - GAAP gross margin was 20.3%, while non-GAAP gross margin was down 530 basis points sequentially and 590 basis points year over year [21][24] Business Line Data and Key Metrics Changes - Automotive revenue was $762 million, a sequential decline of 26%, while industrial revenue was $400 million, down only 4% sequentially [19][20] - Revenue for the Power Solutions Group (PSG) was $645 million, a decrease of 20% quarter over quarter, and for the Analog and Mixed Signal Group (AMG) it was $566 million, down 7% quarter over quarter [20] - The Intelligent Sensing Group (ISG) revenue was $234 million, a 23% decrease quarter over quarter [20] Market Data and Key Metrics Changes - The company noted early signs of stabilization in certain parts of the industrial market, with traditional industrial segments starting to recover [6][60] - Medical and Aerospace and Defense revenues increased sequentially, while AI data center revenue more than doubled year over year [8][19] Company Strategy and Development Direction - The company is focused on streamlining operations through a "fab right" approach and investing in R&D to deliver differentiated products [5][6] - The company aims to increase share repurchase to 100% of free cash flow for 2025, with approximately $1.5 billion remaining on the repurchase authorization [17][16] - The company is committed to building a solid foundation for future growth, particularly in the silicon carbide market, which is expected to ramp significantly in the coming years [9][91] Management's Comments on Operating Environment and Future Outlook - Management expressed cautious optimism about the recovery in the semiconductor market, particularly in automotive and industrial sectors [6][60] - The geopolitical environment remains uncertain, but the company expects minimal direct impact from current tariff policies [6][100] - Management anticipates Q2 revenue in the range of $1,400 million to $1,500 million, with non-GAAP gross margin expected between 36.5% and 38.5% [27][28] Other Important Information - The company reduced internal fab capacity by 12% as part of its manufacturing realignment program, which is expected to lower ongoing depreciation costs by approximately $22 million annually [18][19] - A company-wide restructuring initiative led to a 9% reduction in the global workforce, expected to generate approximately $25 million in savings in Q2 [18][19] Q&A Session Summary Question: Why is ON Semiconductor's revenue guidance flat compared to peers? - Management indicated that the difference is due to the specific end markets ON is exposed to, particularly in automotive EVs, which have not yet seen recovery outside of China [30][31] Question: What metrics should be used to think about gross margin moving forward? - Management stated that for every point of utilization increase, gross margin improves by 25 to 30 basis points, with expectations for improvement as the market recovers [32][34] Question: What has changed regarding pricing? - Management noted that the extended downturn has necessitated a more opportunistic pricing approach to defend and increase market share, rather than a return to previous pricing strategies [39][40] Question: Update on the non-core business exit plan? - Management confirmed the plan to exit the non-core business remains, with approximately $300 million expected to be exited this year, depending on market conditions [47][50] Question: Expectations for demand within the automotive segment by geography? - Management highlighted strength in the Chinese automotive market, particularly driven by EVs, with expectations for new models ramping in the second half of 2025 [76][78] Question: What is the outlook for silicon carbide growth? - Management remains bullish on silicon carbide, expecting to maintain and increase market share, particularly in the growing EV market in China [52][91]

Financial Data and Key Metrics Changes - Second quarter adjusted operating income increased by more than $100 million or 27% year-over-year, with a margin expansion of 70 basis points [9][23] - Adjusted earnings per share grew by 48%, reflecting improved operating performance and strategic execution [9][23] - Enterprise sales for the second quarter were $13.1 billion, which included a reduction of $343 million or 2.6% related to a legal contingency accrual primarily in pork [23][24] Business Line Data and Key Metrics Changes - **Prepared Foods**: Sales were in line with last year, with adjusted operating income increasing nearly 5% and margin improving by 50 basis points [24][25] - **Chicken**: Achieved the best second quarter adjusted operating income in nine years, with a nearly 95% increase compared to the same quarter last year [16][26] - **Beef**: Sales increased primarily due to a higher average price per pound, but adjusted operating income declined due to spread compression [27] - **Pork**: Adjusted operating income increased by 67%, reflecting the strongest second quarter result in the past three years [18][28] Market Data and Key Metrics Changes - 71% of U.S. consumers sought to increase their protein consumption in 2024, indicating robust demand for meat products [10][11] - U.S. meat sales at retail hit an all-time high in 2024, with meat included in nearly 90% of home-cooked dinners [11] Company Strategy and Development Direction - The company is focused on operational excellence, customer and consumer obsession, and capital allocation to drive long-term value [19][32] - A multi-year plan is in place to optimize operations, launch innovations, and expand distribution, particularly in the Prepared Foods segment [13][19] - The company is transitioning to a new logistics and distribution infrastructure, which is expected to generate around $200 million in annual savings upon completion [20][21] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in navigating a dynamic macro environment, emphasizing the importance of their multi-protein, multi-channel portfolio [9][44] - The company anticipates sales growth to be flat to up 1% year-over-year, with adjusted operating income expected between $1.9 billion and $2.3 billion [30][32] - Management acknowledged challenges in the beef segment but remains optimistic about the overall business performance [44][106] Other Important Information - The company is committed to eliminating petroleum-based synthetic dyes from its products, with completion expected by May [21][22] - A new Chief Growth Officer, Christina Lambert, has been appointed to lead strategic initiatives [33][34] Q&A Session Summary Question: Why did the company not raise guidance for the full year despite beating consensus expectations? - Management indicated that while results were strong, they are cautious due to uncertainties in the beef market and consumer pressures, reaffirming guidance for the year [41][46] Question: What is the outlook for chicken demand? - Management remains optimistic about chicken demand, citing strong performance and a commitment to maintaining market share, despite some uncertainties in the industry [49][51] Question: Can you elaborate on the changes in cold storage facilities and expected savings? - Management explained that the transition to new cold storage facilities is aimed at reducing costs and improving efficiency, with expected annual savings of $200 million [56][62] Question: What are the expectations for the international business? - Management highlighted improved operational fundamentals and execution of a commercial growth strategy, leading to strong performance in the international segment [95][96] Question: How does the company view the impact of tariffs on trade flows? - Management does not expect global protein consumption to change significantly but anticipates temporary disruptions as trade flows adjust [121]

Financial Data and Key Metrics Changes - The company reported Q1 revenue of $1.45 billion and non-GAAP earnings per share of $0.55, both exceeding the midpoint of guidance with a non-GAAP gross margin of 40% [6][7][18] - Free cash flow increased by 72% year over year to $455 million, representing 31% of revenue [18][26] - GAAP gross margin was 20.3%, while non-GAAP gross margin was down 530 basis points sequentially and 590 basis points year over year [24][26] Business Line Data and Key Metrics Changes - Automotive revenue was $762 million, a 26% sequential decline, while industrial revenue was $400 million, down 4% sequentially [21][22] - Revenue for the Power Solutions Group (PSG) was $645 million, a decrease of 20% quarter over quarter, and for the Analog and Mixed Signal Group (AMG) it was $566 million, down 7% quarter over quarter [23] - The Intelligent Sensing Group (ISG) revenue was $234 million, a 23% decrease quarter over quarter [23] Market Data and Key Metrics Changes - The company noted early signs of stabilization in the industrial market, particularly in traditional industrial sectors [8][64] - In the automotive sector, leading OEMs are adopting silicon carbide technology, with expectations of significant growth in the Chinese EV market [11][80] Company Strategy and Development Direction - The company is focused on streamlining operations through a "fab right" approach and investing in R&D to enhance gross margins as the market recovers [7][17] - A restructuring initiative led to a 9% reduction in the global workforce, expected to generate approximately $25 million in savings [20] - The company aims to increase share repurchase to 100% of free cash flow for 2025, with $1.5 billion remaining on the repurchase authorization [19] Management's Comments on Operating Environment and Future Outlook - Management expressed cautious optimism about the recovery in certain markets, particularly industrial, while acknowledging ongoing inventory digestion and customer caution [8][9][64] - The geopolitical environment and tariff policies were highlighted as potential risks, but management expects minimal direct impact on the business [8][105] Other Important Information - The company anticipates Q2 revenue in the range of $1.4 billion to $1.5 billion, with non-GAAP gross margin expected between 36.5% and 38.5% [29] - Capital expenditures for Q1 were $147 million, with inventory down by $164 million quarter over quarter [27] Q&A Session Summary Question: Why is the revenue guidance flat compared to peers? - Management indicated that the difference is due to exposure to different end markets, particularly the automotive sector, which has not yet seen recovery outside of China [33][34] Question: What metrics should be used to think about gross margin? - Management stated that for every point of utilization increase, gross margin improves by 25 to 30 basis points, with expectations for improvement as the market recovers [35][36] Question: What has changed regarding pricing? - Management noted that pricing is being used as a tool to defend market share amid a prolonged downturn, with expectations of low single-digit pricing declines [42][43] Question: Update on the non-core business exit? - Management confirmed plans to exit the non-core business, with approximately $50 million already walked away from in Q1, expecting to exit around $300 million by year-end [52][55] Question: What is the outlook for silicon carbide growth? - Management remains bullish on silicon carbide, expecting to maintain and increase market share, particularly in the EV market in China [56][92] Question: What is the status of inventory management? - Management indicated a disciplined approach to channel inventory, with no significant changes expected in distribution inventory levels [68][70]

Zimmer Biomet (ZBH) Q1 2025 Earnings Call May 05, 2025 08:30 AM ET Company Participants David DeMartino - Senior VP of Investor RelationsIvan Tornos - President & CEOSuketu Upadhyay - Executive VP & CFODavid Roman - Managing DirectorTravis Steed - Managing Director - Equity ResearchChris Pasquale - Partner - Medical Devices & SuppliesMatt Taylor - Managing DirectorJoshua Jennings - Managing DirectorJoanne Wuensch. - Managing DirectorCaitlin Cronin - DirectorRichard Newitter - Managing Director Conference Ca ...

Financial Data and Key Metrics Changes - In 2024, the company's full year revenue increased by 32%, reaching $45 billion, with fourth quarter revenue growing by 45% [19] - The company invested nearly $11 billion in R&D, representing about 24% of its revenue, with an 18% year-over-year increase [19] - A new $15 billion share repurchase program was announced, marking the seventh consecutive year of a 15% increase in quarterly dividends [19] Business Line Data and Key Metrics Changes - The performance of Monjaro, Zepbound, and Verzenio significantly contributed to revenue growth [16] - The company launched five new medicines since 2022, including Evolus, Jaypirca, Kisunla, Monjaro, Zepbound, and Omvoh, enhancing patient reach [18] Market Data and Key Metrics Changes - The company expanded its manufacturing capacity to meet increasing demand and opened new facilities, including the Lilly Seaport Innovation Center in Boston and a Lilly Gateway Lab in the UK [20][21] - A major investment in the United States was announced, bringing total manufacturing commitments since 2020 to over $50 billion [21] Company Strategy and Development Direction - The company remains focused on solving serious healthcare problems and aims to deliver life-changing medicines to millions [16] - The long-term balanced growth strategy includes advancements in obesity, diabetes, oncology, neuroscience, and immunology [16] - The company is complementing its pipeline through acquisitions and collaborations, such as acquiring Morphic Therapeutics and partnering with OpenAI [20] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the potential for significant growth from late-stage readouts in 2025 [17] - The company is committed to enhancing supply chain resilience and creating high-paying jobs through its investments [21] - Management emphasized the importance of their workforce and collaborations in achieving their goals [22] Other Important Information - The proposals to amend the articles of incorporation regarding the board structure and voting provisions did not receive the required votes [15] Q&A Session Summary Question: Does the compensation committee use the compensation actually paid total in setting the CEO target total compensation award for the coming year? - Management clarified that the compensation actually paid is not used to set the target compensation, as it reflects a mark-to-market value rather than actual compensation [26][28] Question: How much training is provided to employees to prevent clicking on links resulting in malware or breaks in cybersecurity? - Management confirmed that a comprehensive cybersecurity program is in place, including training to prevent incidents related to malware [29]

Financial Data and Key Metrics Changes - U.S. net product revenue for Q1 2025 was approximately $119.7 million, reflecting a 137% increase year-over-year and a 16% increase sequentially from Q4 2024 [14][23] - GAAP net income for the quarter was approximately $5 million, or $0.03 per diluted share [24] - The company closed the quarter with $276 million in cash, cash equivalents, and investment securities, indicating a strong financial position [24] Business Line Data and Key Metrics Changes - BRIONVI U.S. net sales reached nearly $120 million in Q1 2025, exceeding expectations and demonstrating strong adoption by healthcare providers [5][14] - The first three months of 2025 marked the highest total new patient enrollment since the product launch, indicating accelerating demand [15] - Repeat prescriptions have now surpassed new prescriptions for the first time, signaling strong persistence trends [17] Market Data and Key Metrics Changes - The company is capturing approximately 25% of the IV segment market share, with continued growth in patient enrollments [29] - The hospital setting contributed approximately 60% of enrollments in March, the highest percentage to date [16] Company Strategy and Development Direction - The company aims to make BRIONVI the number one prescribed anti-CD20 therapy by focusing on a multi-phase launch strategy and enhancing the patient experience [8][12] - Plans include launching a direct-to-patient television commercial campaign and preparing for lifecycle innovations, including a subcutaneous formulation [19][21] - The company is also exploring new indications for BRIONVI, such as myasthenia gravis, while advancing its CAR T cell therapy pipeline [11][12] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about continued growth and potential for BRIONVI, citing strong demand and increasing prescriber confidence [20][21] - The company is monitoring potential tariffs but does not anticipate a material impact on gross margins or overall financial performance [26] Other Important Information - The ENHANCE clinical trial is evaluating strategies to simplify the patient experience, with positive feedback on a streamlined infusion regimen [9][10] - The company is on track to launch pivotal trials for both the simplified starting dose and the subcutaneous formulation of BREONVY [52][68] Q&A Session Summary Question: Competitive dynamics with OCREVUS and new patient share - Management noted strong patient enrollments and market share gains, with no impact from OCREVUS observed [29][30] Question: Update on gross to net trends and gross margin - No material change in gross to net was reported, and the pre-launch inventory reserve has been fully depleted, leading to consistent margins going forward [37][38] Question: Subcutaneous BREONVY pivotal trial details - The pivotal trial is expected to include two dosing regimens, with data anticipated later this year [41][42] Question: Physician feedback on the thirty-minute infusion - Positive feedback was received, indicating convenience for infusion centers and patients [49] Question: Phase III trial scale and profitability outlook - The company is not focused on profitability this year but aims to drive cash through the business while meeting revenue targets [54][55] Question: Update on North Carolina manufacturing plant - The North Carolina facility will take several years to reach commercial scale manufacturing [57][58] Question: Product adherence and trends - Persistence trends remain strong and above expectations, with no material changes in switch rates from OCREVUS [63][71]

Financial Data and Key Metrics Changes - In Q1 2025, Zimmer Biomet reported net sales of $1.909 billion, reflecting a 1.1% increase on a reported basis and a 2.3% increase excluding foreign currency impact [27] - Adjusted earnings per share (EPS) for the quarter was $1.81, down from $1.94 in the prior year, attributed to higher costs and investments [32] - The company generated $279 million in free cash flow, demonstrating robust growth compared to the previous year [26] Business Line Data and Key Metrics Changes - U.S. hips sales grew nearly 4%, while U.S. knees saw a modest growth of 0.2% [29] - The S.E.T. segment grew by 4.9%, with notable growth in CMFT and Sports categories [30] - International sales grew by 3.7%, driven by mid-single digit growth in knees and high-single digit growth in S.E.T. [28] Market Data and Key Metrics Changes - The U.S. market showed a 1.3% growth overall, with hips and S.E.T. driving performance [27] - Internationally, hips grew by 2.4%, with U.S. hips growing at 3.7% and international hips at 1% [29] - The company anticipates a full-year organic constant currency revenue growth of 3% to 5% for 2025 [10] Company Strategy and Development Direction - Zimmer Biomet is focusing on three strategic priorities: people and culture, operational excellence, and innovation and diversification [12] - The company aims to enhance its U.S. market performance through leadership changes and optimizing sales channels [14] - The recent acquisition of Paragon 28 is expected to contribute approximately 270 basis points to sales growth in 2025 [11] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving the full-year guidance despite challenges such as tariffs and foreign exchange impacts [34] - The company is optimistic about new product launches and expects second-half growth to be higher than the first half due to favorable comparisons and new product uptake [35] - Management acknowledged the need for improved performance in the U.S. knee segment and is implementing strategies to enhance competitiveness [81] Other Important Information - The company reported a reduction in days on hand inventory from over 400 days in early 2024 to approximately 370 days [15] - The Paragon 28 acquisition was successfully integrated with minimal disruption, retaining key leadership and sales teams [110] Q&A Session Summary Question: Impact of tariffs on EPS and mitigation efforts - Management detailed steps taken to mitigate tariff impacts, including optimizing country of origin and sourcing adjustments, expecting a $60 million to $80 million headwind for 2025 [45][46] Question: Growth expectations and new product impacts - Management indicated confidence in achieving mid-single digit growth in the second half of 2025, driven by new product launches and improved execution [56][57] Question: Performance in ASC versus hospital channels - The company noted that over 20% of U.S. sales now come from the ASC environment, with expectations for continued growth in this area [94] Question: Pricing trends and future expectations - Management expects pricing to remain flat for 2025, with a stable environment compared to historical norms, despite previous fluctuations [68][69] Question: Clarification on the Paragon acquisition integration - The integration of Paragon 28 is progressing well, with all key personnel retained and ongoing product innovations maintained [110]