点击免费限量礼盒 摘要 ： 澄观光学突破无标记超分辨显微技术，推动生命科学观测革新。由于无需额外标记物，无标记光学成像避免了对样品进行固定、切片、染色等损伤性操 作，能够实现非侵入、长时程的活体观测，多研究领域有巨大优势。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 高端光学显微镜作为生命科学、材料科学、半导体检测、精密制造等领域的核心观测工具，突破了传统显微镜的分辨率与应用局限，以超分 辨、高灵敏度、多维成像等优势，推动科研从"宏观表征"向"微观机制解析"跨越，从"静态观测"向"动态追踪"升级。 当前，全球高端光学显微镜市场正迎来技术迭代加速期，国产设备也奋起直追，在多个细分领域实现关键突破。为全面展现我国高端光学显微 镜技术的发展态势、创新成果与产业潜力，仪器信息网将推出 "高端光学显微镜技术进击潮"专题 ，并向相关企业、科研机构广泛约稿，本篇 为澄观光学 供稿。 自17世纪光学显微镜发明并助力人们观察到细胞后，其一直是细胞生物学研究的关键工具。光学显微镜作为一种无损探测手段，在生命科学与 医学研究中得到了广泛应用。传统的光学显微镜 ...

点击免费限量礼盒 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 12月9日，九强生物晚间发布公告称，公司股东邹左军、刘希、孙小林与 中国医药投资有限公司（以下简称"国药投资"） 签署《股份转让协 议》，前者拟通过协议转让方式向国药投资合计转让2931.54万股股份，占九强生物总股的5%，交易总价款达4.01亿元，每股转让价格为 13.68元。 主营业务为生化诊断、血凝检测、血型检测和肿瘤病理检测的研发、生产和销售。2020年，在国药投资正式成为九强生物第一大股东后，九强 生物与国药投资联手收购迈新生物，布局肿瘤筛查诊断，扩充病理诊断试剂和仪器产品线，提升技术研发能力和营销网络布局。 在福布斯排行榜中，九强生物是全国中小企业中唯一一家连续9年上榜的中国潜力100强企业 。 | 版 权 ： 本 文 部 分 素 材 源 自 网 络 ， 版 权 归 原 作 者 所 有 ， 观 点 代 表 作 者 本 人 ， 不 代 表 本 号 立 场 | 转 载 ： 须 本 号 授 权 ， 请 联 系 主 编 | 责 编 ： 安 安 | 视 觉 ： 长 艳 柱 ...

Core Insights - The article highlights the annual selection of the "Top Ten Advances in Life Sciences in China" by the Chinese Association for Science and Technology, showcasing significant innovations in the field aimed at enhancing public health and addressing critical issues in life sciences [2][36]. Group 1: Innovations in Cancer Treatment - A new strategy for enhancing and reducing toxicity in nasopharyngeal cancer immunotherapy has been developed, demonstrating a 44% reduction in failure risk and an increase in survival rate from 77.3% to 86.9% through the use of PD-1 monoclonal antibodies [4]. - The research also led to a decrease in chemotherapy-induced vomiting rates from 59.8% to 26.2% and reduced severe radiation therapy side effects from 33.2% to 21.6% [4]. Group 2: Caloric Restriction and Longevity - Research from Xiamen University identified a molecule called taurocholic acid that significantly increases in serum after caloric restriction, promoting health and longevity across various animal models [7]. - The study revealed that taurocholic acid activates the TULP3 receptor, which in turn activates Sirtuins, linking to the AMPK pathway, thus providing a theoretical basis for developing interventions that mimic caloric restriction effects [9]. Group 3: Neuroregeneration in Stroke Treatment - A novel "brain repair gel" developed by a collaborative team aims to improve the microenvironment post-stroke, promoting the regeneration of neurons and restoring sensory-motor functions [11]. - This approach marks a paradigm shift from passive protection to active regeneration in stroke treatment, with ongoing clinical trials validating its safety and efficacy [13]. Group 4: Metabolite Diversity and Disease Intervention - A team from Peking University discovered new gut microbiota-derived metabolites that regulate metabolic diseases, identifying orphan receptors as new targets for intervention [15]. - The research utilized AI to uncover specific synthetic enzymes, leading to the development of targeted intervention strategies for metabolic disorders [15]. Group 5: Advances in Genetic Engineering - The Chinese Academy of Sciences has developed an AI-driven protein engineering method that enables large-scale precise editing of DNA, which could revolutionize genetic disease treatment and crop breeding [24]. - This breakthrough represents a significant advancement in the application of AI in life sciences, showcasing the potential for deep learning to address biological challenges [24]. Group 6: Aging Interventions - Research teams have created a "protein scale" to quantify organ aging and identified key mechanisms driving aging, including the role of betaine as a "exercise mimetic" that slows multi-organ aging [26]. - The study also developed engineered anti-aging stem cells that can provide systemic protection against inflammation, contributing to the advancement of precision medicine in aging research [26]. Group 7: Insect Pheromone Research - A comprehensive analysis of locust aggregation pheromones has been conducted, leading to the development of specific inhibitors that can effectively control locust behavior [19]. - This research provides a foundational understanding for developing precise pest control strategies, marking a significant achievement in the field of entomology [19]. Group 8: Deep-Sea Evolutionary Mechanisms - A collaborative study has decoded the evolutionary processes of deep-sea animals, revealing how they adapt to extreme environments and providing insights into biodiversity [34]. - The findings challenge previous notions about deep-sea evolution, highlighting it as a site of innovation rather than a terminus for life [34].

Core Viewpoint - The article highlights the establishment of a shared ecological environment monitoring instrument platform in Shandong Province, which aims to enhance monitoring capabilities and resource efficiency through the sharing of equipment among various monitoring centers [3][4]. Group 1: Instrument Sharing Mechanism - Shandong Province has pioneered a shared instrument mechanism, allowing for the borrowing of monitoring equipment among different ecological environment monitoring centers, resulting in significant cost savings and improved resource utilization [2][3]. - The platform has integrated 1,845 sets of monitoring instruments valued at 570 million yuan, facilitating cross-regional equipment allocation and saving approximately 25.1 million yuan in equipment procurement costs [3][4]. Group 2: Implementation and Training - The Shandong Provincial Ecological Environment Monitoring Center has organized training sessions and workshops to promote the sharing mechanism, ensuring that 25 provincial agencies actively participate in the initiative [5]. - Since March 2025, 311 sets of shared equipment valued at approximately 95.4 million yuan have been recorded on the platform, enhancing the accessibility of monitoring resources [5]. Group 3: Cross-Regional Collaboration - The platform has successfully enabled cross-city sharing of monitoring instruments, exemplified by the timely borrowing of a gas mixing instrument between monitoring centers in Dongying and Heze, saving 4.21 million yuan in equipment costs [6][7]. - The collaboration has led to the addition of 11 new monitoring projects, including marine ecological monitoring and biodiversity observation, demonstrating the effectiveness of the shared resource model [7]. Group 4: Extension to Local Levels - The establishment of "open laboratories" allows for the sharing of laboratory instruments and facilities with local monitoring agencies, addressing the capacity limitations at the district and county levels [8]. - Various local monitoring centers have developed their own sharing plans, integrating equipment from multiple units to enhance monitoring capabilities [8]. Group 5: Collaboration with Research Institutions - The Shandong Provincial Ecological Environment Monitoring Center is collaborating with social research institutions to provide shared services, aiming to improve both research capabilities and equipment utilization [9]. - The ongoing efforts to establish a three-tiered sharing mechanism across provincial, municipal, and county levels are expected to enhance the overall efficiency of monitoring instrument usage [9].

特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 福利二 哈希水质应用进阶：看见新场景，发现新增长 申领规则 ：识别下方二维码或点击"阅读原文" 按照要求填写信息完成登记参与活动，将有机会获得惊喜礼盒，数量有限，先到先得，送完即 止！ 注：礼品仅发放给哈希用户及水质分析、环监等行业从业人员，不包含哈希经销商;礼品发放需经过客服电话核实，未核实用户将不予发放礼品，请您注意接听来自西安的(029开头)哈希 客服电话。 识别二维码或点击文末"阅读原文" 免费申领礼盒 哈希作为拥有70多年历史的水质分析仪器专业公司，以水质监测检测设备见长，以世界水质守护者为公司使命。今天， 哈希和小编 给大家带 来两重福利 ： 福利一 哈希 水质守护者专属礼盒申领 哈希特别为各位水质守护者献上 专属感恩礼盒 ，以惊喜好礼陪伴您继续奔赴守护碧水的前行之路。愿这份心意化作温暖的力量，与您继续携 手守护碧水清波，共筑水环境保护的坚实屏障。 HACH 溶解氢氧电厂的应用 141/ LOJUNIA 30.7 the la 铜筒子检测 EBDO工艺中的应用 新能源时代的"黄金康 ...

Core Viewpoint - The establishment of the Dongguan Institute of Materials Science and Technology by the Chinese Academy of Sciences aims to create a globally influential research center focused on strategic and frontier materials exploration and fundamental scientific issues [2]. Group 1 - The Dongguan Institute is a collaborative research institution built by the Chinese Academy of Sciences, Guangdong Province, and Dongguan City [2]. - The institute will focus on research in various fields, including information materials, energy materials, functional ceramics, and metal materials [2]. - The goal is to enhance the global influence and leadership in new materials research [2].

Core Viewpoint - The article highlights the successful overseas application of domestic high-end clinical instruments by 聚光科技, particularly focusing on the deployment of their fully automated capillary electrophoresis instrument in Vietnam, which demonstrates the company's capability in providing localized solutions for complex clinical needs [5][19]. Group 1: Company Overview - 聚光科技 specializes in the independent research and development of high-end scientific instruments, focusing on industry-specific application needs and providing domestic, intelligent system solutions across key sectors such as ecological environment, industrial manufacturing, higher education research, and life sciences [2]. Group 2: Product Application and Performance - The fully automated capillary electrophoresis instrument from 聚拓生物 is operational in a comprehensive hospital in Hanoi, Vietnam, aiding local doctors in risk assessment for thalassemia [5]. - The instrument has been optimized to adapt to local sample characteristics, addressing the complexity of thalassemia in Vietnam, where genetic diversity and sample structure present unique challenges [7][8]. - The instrument's algorithm has been specifically optimized to enhance the recognition of HbE variant characteristics and key peak features, improving the stability and interpretability of electrophoresis results [8][10]. Group 3: Clinical Implementation and Feedback - The initial deployment faced challenges due to the complexity of local clinical samples, requiring careful calibration and parameter optimization to ensure reliable and repeatable readings [11][12]. - Continuous on-site analysis and remote collaboration were conducted to enhance the stability of peak recognition, leading to clearer and more stable peak shapes as reported by local clinical teams [13][16]. - The successful implementation and positive feedback from local medical staff reflect the technical strength of the instrument and the comprehensive service system provided by 聚拓生物 [17]. Group 4: Global Expansion and Future Outlook - The successful case in Vietnam serves as a strong practical example for 聚拓生物's overseas expansion, with recent project wins for the capillary electrophoresis instrument in Germany and Congo [19]. - The life sciences segment of 聚光科技 has also delivered multiple applications of its liquid chromatography-tandem mass spectrometry (LC-MS/MS) systems overseas, expanding the international application boundaries of domestic high-end scientific instruments [19]. - The company aims to continue promoting precise detection solutions tailored to the clinical needs of different countries and regions, facilitating the global reach of Chinese life science technology [23].

点击免费限量礼盒 此前，浙江 省经信厅、省财政厅于11月7日发布了《关于组织实施2 0 2 6年度生产制造方式转型（工业领域设备更新） 示范项目计划的通知》（后文简称"《通知》"）。 《通知》中明确2 0 2 6年工业领域设备更新重点支持领域：信息技术产业领域、 装备工业领域、 材料工业领域、 医药 和医疗器械领域、 消费品工业领域。其中装备工业领域中涵盖了 仪器仪表 、 先进环保装备 等。 在这些重点领域中，重点支持的更新内容为： 企业淘汰落后低效设备、超期服役老旧设备，更新应用先进高效设备和 试验检验设备 ，加快工艺流程、 生产设备绿色化 、 智能化改造 。并且重点提升工业设计中心、 计量和检验检测中 心 、 认证中心 、共性技术平台、中试验证基地专业化、高端化、综合性生产服务能力。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 12 月 10 日 至 11 日 ， 中 央 经 济 工 作 会 议 在 北 京 举 行 。 此 次 会 议 部 署 2026 年 经 济 工 作 ， 其 中 在 部 署 明 年 " 坚 持 内 需 主 导， ...

Core Insights - The article highlights the recent announcement of 21 government procurement intentions for various instruments and equipment, with a total budget of 551 million yuan, expected to be procured by December 2025 [1][2]. Procurement Overview - The procurement includes a range of advanced equipment such as optical microscopes, low-pressure plasma-enhanced chemical vapor deposition systems, specialized deep silicon etching machines, multi-chamber cascade film growth systems, atomic layer deposition systems, and critical dimension scanning electron microscopes [1][3]. - The total budget for these procurement intentions is 551 million yuan, indicating significant investment in high-tech instrumentation [1][2]. Detailed Procurement List - The procurement list includes: - 72 optical microscopes for R&D support, budgeted at 25.2 million yuan [3]. - 6 source measurement units for electrical performance testing, budgeted at 4.5 million yuan [3]. - 8 sets of oil-free vacuum pumps for cleanroom applications, budgeted at 1.36 million yuan [3]. - 1 set of low-pressure plasma-enhanced chemical vapor deposition systems for high-quality silicon film deposition, budgeted at 17.5 million yuan [4]. - 2 specialized deep silicon etching machines for high-precision etching, budgeted at 34.62 million yuan [4]. - 2 multi-chamber systems for seamless growth of heterostructures, budgeted at 195 million yuan [4]. - 1 atomic layer deposition system for precise control of thin films, budgeted at 18 million yuan [4]. - 1 critical dimension scanning electron microscope for nanoscale measurements, budgeted at 14.36 million yuan [4]. - Additional equipment includes automated systems for various processes, such as developing and etching, with budgets ranging from 1.5 million to 30 million yuan [4][5]. Conclusion - The procurement intentions reflect a strong commitment to advancing research and development capabilities in high-tech fields, particularly in quantum technology and semiconductor manufacturing [1][2].

Core Viewpoint - The Mexican Congress has approved a tariff amendment that imposes a maximum 50% import duty on goods from countries without a free trade agreement with Mexico, including China, India, and South Korea, with the final version setting most product tariffs at 35% [1][2]. Group 1: Tariff Amendment Details - The amendment was passed by the Mexican House of Representatives on December 10, 2025, with a vote of 281 in favor, 24 against, and 149 abstentions [1]. - The initial proposal targeted nearly 1500 product categories with a maximum 50% tariff, but due to domestic and international opposition, the majority of categories now have a reduced tariff rate of 35% [1]. - The base tariff rate for instruments and meters is set at 35%, aligning with the category of "machinery and electrical equipment" [1]. Group 2: Impact on Chinese Exports - In 2024, China's exports of instruments and meters to Mexico are estimated to be around $1.2 billion, accounting for 1.3% of China's total exports to Mexico, which is approximately $90.23 billion [2]. - Following the implementation of the tariff amendment, the tariff cost for general instruments and meters will increase by approximately 15-20 percentage points, leading to a decrease in price competitiveness of about 10-15% for Chinese instruments in the Mexican market [2].