Core Viewpoint - Goldman Sachs reports that King's Ray Biotechnology (01548) has mixed performance in the first half of fiscal year 2025, with gross margins under pressure, but sales outside of Legend Biotech generally meet expectations [1] Group 1: Financial Performance - The management has slightly adjusted the guidance for the life sciences business in 2025 from 10% to 15% to 13% to 15%, expecting steady growth in this segment [1] - Goldman Sachs maintains a "Buy" rating for King's Ray, with a target price reduced from HKD 27.34 to HKD 26.25 [1] - Earnings per share forecasts for 2025 to 2027 have been revised down from USD 0.07, USD 0.05, and USD 0.10 to losses of USD 0.03, USD 0.01, and a profit of USD 0.03, reflecting pressure on profitability [1]

Core Viewpoint - Kingsray Biotechnology (01548) reported significant growth in its interim results, with a notable increase in revenue and a substantial reduction in losses, indicating a positive trajectory for the company [1] Financial Performance - The revenue from continuing operations reached $519 million, representing a year-on-year increase of 81.92% [1] - The loss attributable to the parent company was $25.46 million, which is a reduction of 85.46% compared to the previous year [1] - Adjusted net profit stood at $178 million, showing a remarkable year-on-year growth of 509.6% [1] CDMO Revenue - The CDMO (Contract Development and Manufacturing Organization) revenue for the first half of the year was $250 million, reflecting a year-on-year increase of 511.1% [1] - A one-time prepayment related to the partnership with Lixin has been confirmed and received, amounting to $214 million, with a double-digit growth rate when excluding this amount [1] Impact of Joint Ventures - The joint venture with Legend Biotech resulted in a loss impact of $194 million for Kingsray, contributing to the net loss for the parent company [1] - Legend Biotech is expected to achieve adjusted net profit in the second quarter of 2025 and aims for overall profitability by 2026 [1] - The core product CARVYKTI from Legend Biotech achieved net sales of $439 million in the second quarter of 2025, marking a year-on-year growth of 136%, which is anticipated to support significant improvement in Kingsray's net profit by 2026 [1]

Core Viewpoint - Kingsoft Biotech (01548) reported significant growth in its mid-term performance, with a notable increase in revenue and a substantial reduction in losses, indicating a positive trend for the company moving forward [1] Financial Performance - The revenue from continuing operations reached $519 million, representing a year-on-year increase of 81.92% [1] - The loss attributable to the parent company narrowed to $25.46 million, a reduction of 85.46% year-on-year [1] - Adjusted net profit stood at $178 million, showing a remarkable growth of 509.6% compared to the previous year [1] CDMO Segment - The CDMO revenue for the first half of the year amounted to $250 million, reflecting a year-on-year increase of 511.1% [1] - Confirmed and received payments related to the one-time advance from the collaboration with Lixin totaled $214 million, with a double-digit growth rate when excluding this amount [1] Impact of Joint Ventures - The losses from the joint venture Legend Biotech impacted Kingsoft Biotech by $194 million, contributing to the net loss reported [1] - Legend Biotech is expected to achieve adjusted net profit in the second quarter of 2025 and aims for overall profitability by 2026 [1] - The core product CARVYKTI from Legend Biotech generated net sales of $439 million in the second quarter of 2025, marking a year-on-year growth of 136%, which is anticipated to support significant improvement in Kingsoft Biotech's net profit by 2026 [1]

Core Viewpoint - Kingsoft Biotech (01548) reported significant growth in its interim results, with a notable increase in revenue and a substantial reduction in losses, indicating a positive trajectory for the company [1] Financial Performance - The revenue from continuing operations reached $519 million, representing a year-on-year increase of 81.92% [1] - The loss attributable to the parent company narrowed to $25.46 million, a reduction of 85.46% compared to the previous year [1] - Adjusted net profit stood at $178 million, showing a remarkable year-on-year growth of 509.6% [1] CDMO Segment - The CDMO (Contract Development and Manufacturing Organization) revenue for the first half of the year was $250 million, reflecting a year-on-year increase of 511.1% [1] - A one-time prepayment related to the partnership with Lixin has been confirmed and received, amounting to $214 million, with a double-digit growth rate when excluding this amount [1] Impact of Joint Ventures - The joint venture with Legend Biotech resulted in a loss impact of $194 million for the first half of the year, affecting Kingsoft Biotech's net profit [1] - Legend Biotech is expected to achieve adjusted net profit in the second quarter of 2025 and aims for overall profitability by 2026 [1] - The core product CARVYKTI from Legend Biotech achieved net sales of $439 million in the second quarter of 2025, marking a year-on-year growth of 136%, which is anticipated to support Kingsoft Biotech's net profit improvement in 2026 [1]

Core Viewpoint - The Hong Kong biopharmaceutical stocks experienced a general increase, driven by government support for the industry, particularly emphasized by Premier Li Qiang during his recent visit to Beijing [1] Industry Summary - The biopharmaceutical sector in Hong Kong saw significant stock price increases, with notable gains including 5% for Fuhong Hanlin, 3.6% for King’s Ray Biopharmaceutical, and over 3% for WuXi AppTec [1] - Premier Li Qiang highlighted the need for enhanced high-quality technological supply and policy support to promote the development of the biopharmaceutical industry, aiming to produce more high-quality and efficient new drugs [1] - Continuous high-level endorsements from the government signal a strong commitment to supporting the biopharmaceutical industry, especially in the current economic context [1] Company Summary - Fuhong Hanlin (02696) latest price: 83.000, change: +5.06% [1] - King’s Ray Biopharmaceutical (01548) latest price: 17.940, change: +3.64% [1] - WuXi AppTec (02268) latest price: 59.600, change: +3.38% [1] - Other companies with notable increases include: - Keren Biotechnology (06990) +3.29% - Kangfang Biopharmaceutical (09926) +2.83% - Rongchang Biopharmaceutical (09995) +2.87% - Junshi Biosciences (01877) +2.69% - BeiGene (06160) +2.60% [1]

Core Insights - The article highlights the significant growth and strategic advancements of the company, Kingsoft, in the context of a rapidly evolving global environment, particularly in the innovative pharmaceutical sector [1][21] - The company has achieved remarkable financial results in the first half of 2025, with a substantial increase in revenue and profit, indicating strong operational resilience and growth potential [2][16] Financial Performance - In the first half of 2025, the company reported a revenue of $518.8 million, representing a year-on-year increase of 81.9% [2] - The gross profit reached $320.6 million, up 140.1% year-on-year, while the adjusted net profit from continuing operations surged to $178 million, a staggering increase of 509.6% [2] - The company’s cash reserves stood at $967 million as of June 30, 2025, providing a solid foundation for future research and development investments [2] Business Segments - **Life Sciences Services and Products**: This segment generated $247.6 million in revenue, a growth of 11.3% year-on-year, with a notable increase in the share of custom protein services [5][6] - **Biopharmaceutical CDMO**: The CDMO business saw a remarkable revenue increase of 511.1% to $246.9 million, driven by advancements in antibody protein drugs and cell gene therapy [10][11] - **Industrial Synthetic Biology Products**: Revenue in this segment reached $28.3 million, growing by 8.4% year-on-year, with strong performance in the enzyme market [13] - **Cell Therapy**: The company’s joint venture, Legend Biotech, reported net sales of approximately $439 million for CARVYKTI, marking a 136% increase, with expectations of reaching operational breakeven by the end of 2025 [14] Strategic Initiatives - The company is focusing on global expansion and automation, with plans to achieve full automation in its four major factories by the end of 2025, enhancing production efficiency and supply chain resilience [6][17] - Kingsoft is leveraging its technological advancements and strategic partnerships to enhance its market position and drive future growth [16][19] Market Outlook - The recovery of the innovative pharmaceutical market is expected to boost demand for CXO services, providing ongoing growth momentum for the company [16] - The company’s management is optimistic about future performance, projecting a revenue growth of 13%-15% for the life sciences business and maintaining a strong outlook for its other segments [18][19]

Core Viewpoint - The company reported strong performance in 1H25, with significant revenue growth and improved profitability metrics, indicating a positive trend in its business operations [1][2]. Financial Performance - The company achieved revenue of $519 million in 1H25, representing a year-on-year increase of 81.9%, with adjusted net profit of $178 million and a net profit margin of 34.3% [1]. - The gross profit was $321 million, corresponding to a gross margin of 61.8%, reflecting enhanced profitability driven by increased capacity utilization and product upgrades [1]. - The net loss attributable to shareholders was $25 million, significantly narrowed from previous periods, primarily due to a $194 million investment loss from a joint venture [1]. Business Segments - The life sciences segment generated $250 million in revenue, up 11.3% year-on-year, driven by strong growth in protein business (52% growth) and demand for gene editing and AI-related R&D [1]. - The CDMO segment saw revenue reach $250 million, a remarkable increase of 511.1%, with a significant one-time payment of $214 million from a licensing agreement [2]. - The industrial synthetic biology segment reported revenue of $3.9 million, an 8.4% increase, although it faced operational losses due to increased R&D investments [2]. Development Trends - The company is focusing on global expansion and strengthening its market position in the life sciences sector, with ongoing investments in sales and R&D to enhance long-term competitiveness [1][2]. - The company expects to achieve key milestones in its CDMO business by the end of 2025 to early 2026, including potential licensing transactions [2]. Profit Forecast and Valuation - The company maintains its profit forecasts for 2025 and 2026, with an upgraded target price of HKD 21.50, reflecting a 22.2% increase based on DCF valuation, indicating a potential upside of 21.3% from current stock prices [2].

Core Viewpoint - The CESHKB index has shown significant growth, with a year-to-date increase of 123.13%, indicating a strong performance in the biotechnology sector listed in Hong Kong [1][2]. Group 1: Index Performance - The CESHKB index opened high but experienced a decline of 1.85%, closing at 9813.36 points with a trading volume of 19.304 billion [1]. - Over the past month, the CESHKB index has risen by 12.30%, and over the last three months, it has increased by 73.10% [1]. Group 2: Index Composition - The CESHKB index is compiled by China Securities Index Co., Ltd. under the commission of China Securities Trading Service Co., Ltd., reflecting the overall performance of biotechnology companies listed in Hong Kong [1]. - The top ten holdings in the CESHKB index include: - CanSino Biologics (14.32%) - Innovent Biologics (9.54%) - BeiGene (8.5%) - 3SBio (8.48%) - WuXi Biologics (8.32%) - WuXi AppTec (6.53%) - Kintor Pharmaceutical (5.21%) - Zai Lab (4.35%) - Ascletis Pharma (4.17%) - Kingstar Biotech (3.84%) [1]. Group 3: Market and Industry Overview - The CESHKB index is entirely composed of companies listed on the Hong Kong Stock Exchange, with a 100% representation from the healthcare sector [2].

Core Viewpoint - The report from CMB International indicates an upward revision of Kingsray Biotechnology's (01548) revenue forecast for 2025-2027 by 1-5%, while lowering the net profit forecast for 2025 due to significant net losses in the first half of 2025 [1] Group 1: Financial Performance - The group's performance for the first half of 2025 met expectations, with revenue from continuing operations increasing by 82% to $519 million [1] - Adjusted net profit surged by 510% to $178 million [1] Group 2: Business Segment Outlook - The group has raised its revenue growth guidance for the life sciences segment for the full year to 13-15%, with an expected growth rate of 15-18% for the second half of the year [1] Group 3: Valuation and Rating - The SOTP model has been rolled forward to 2026, maintaining the target valuation multiples for each business segment [1] - The target price remains at HKD 28.75, with a "Buy" rating retained [1]

Core Viewpoint - The report from CMB International indicates an upward revision of Kingsray Biotechnology's (01548) revenue forecast for 2025-2027 by 1-5%, while lowering the net profit forecast for 2025 due to significant net losses in the first half of 2025 [1] Group 1: Financial Performance - The group's performance for the first half of 2025 met expectations, with a year-on-year revenue increase of 82% to $519 million [1] - Adjusted net profit surged by 510% to $178 million [1] Group 2: Business Segment Outlook - The company raised its full-year revenue growth guidance for the life sciences segment to 13-15%, with a corresponding growth rate of 15-18% expected in the second half of the year [1] Group 3: Valuation and Rating - The SOTP model has been rolled forward to 2026, maintaining the target valuation multiples for each business segment [1] - The target price remains at HKD 28.75, with a "Buy" rating upheld [1]