9月11日，创新药纯度100%的港股通创新药ETF（520880）场内一度暴跌近8%，盘中溢价高企，显示买 盘资金尤为强劲。昨日，资金逢跌加仓港股通创新药ETF（520880）9849万元。至此，520880已连续7 日吸金，金额合计近2.8亿元。 9月8日，港股通创新药ETF（520880）跟踪的恒生港股通创新药精选指数"提纯"修订生效，全面剔除药 明系等CXO个股，同时新纳入14只纯正创新药企业，正式成为一只不含CXO、纯度100%的创新药指 数。本次"提纯"修订生效后，将彻底避免CXO对标的指数走势的干扰，有望在后续创新药行情启动时展 现出更强进攻性。据恒生指数公司统计，剔除CXO后，恒生港股通创新药精选指数历史回溯表现显著 更优。 今年以来，港股通创新药ETF（520880）跟踪的恒生港股通创新药精选指数在同类指数中进攻力 MAX，截至"提纯"修订生效前（9月5日），其年内累计涨幅达119.75%，领涨一众创新药指数。 展望后市，方正证券表示，创新药长牛行情或远未结束，中国工程师红利带来的创新药资产尚未充分兑 现商业化价值。港股创新药板块估值较低，BD落地数量多且确定性高，未来大赛道如小核酸、口服 G ...

Group 1 - The Hong Kong stock market for innovative drugs opened high but fell, with Zai Lab leading the decline by over 13% and other companies like Innovent Biologics and Ascentage Pharma dropping over 5% [1] - The Hong Kong Stock Connect Innovative Drug ETF (520880) experienced a significant drop of over 4%, with a trading volume of nearly 350 million yuan [1] - The ETF had previously seen four consecutive days of gains, reaching a new closing high [1] Group 2 - The World Lung Cancer Conference (WCLC) will take place from September 6 to 9 in Barcelona, Spain, where Chinese pharmaceutical companies will showcase innovative drug results [3] - Companies such as CanSino Biologics, BeiGene, and Baillie Gifford will present their latest research during the conference [3] - The upcoming conferences and the peak season for licensing agreements with multinational pharmaceutical companies (MNCs) are expected to create a favorable environment for innovative drugs in the coming quarter [3] Group 3 - The Hong Kong Stock Connect Innovative Drug ETF (520880) has shown strong performance, with a year-to-date increase of 118.95%, leading among various innovative drug indices [3][4] - The ETF is set to revise its index compilation rules to exclude companies primarily engaged in CXO services, focusing solely on innovative drug research and development [5] - This revision is expected to enhance the ETF's performance during the upward cycle of the innovative drug industry [5]

Group 1 - The Hong Kong innovative drug sector is experiencing a significant pullback, with the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index dropping nearly 4% and most constituent stocks declining [1] - Major stocks such as Kelun-Botai Biopharmaceutical, CanSino Biologics, and Zai Lab fell over 5%, while China Biologic Products and 3SBio dropped over 4% [1] - The Hong Kong Stock Connect Innovative Drug ETF (520880) saw a price drop of over 4% but later reduced its decline, indicating positive buying sentiment with a real-time premium rate exceeding 0.4% [1] Group 2 - The Hang Seng Hong Kong Stock Connect Innovative Drug Select Index has risen 101.58% year-to-date as of July 31, significantly outperforming the Hang Seng Index and Hang Seng Technology Index by 78.08 and 79.53 percentage points, respectively [2] - The ETF is the first in the market to track this index, focusing on the innovative drug industry chain with a high concentration of leading companies [2]

Core Viewpoint - The innovative drug sector is experiencing a rebound, with the Hong Kong Stock Connect Innovative Drug ETF (520880) showing a positive performance after a brief decline, indicating renewed investor interest in the sector [1][3]. Company Performance - LIZHU Pharmaceutical reported a mid-year revenue of approximately 6.272 billion yuan, a slight decrease of 0.17% year-on-year, while net profit attributable to shareholders increased by 9.4% to about 1.281 billion yuan [2]. - The company has 39 products in the research pipeline, with 13 in the registration phase, 4 in Phase III clinical trials, 2 in process validation/BE phase, and 4 in Phase II clinical trials [2]. Industry Trends - High-level leaders emphasized the need for increased high-quality technological supply and policy support for the biopharmaceutical industry, aiming to enhance the quality and efficiency of drug development [3]. - CICC expressed optimism about the long-term development trend of innovative drugs, highlighting the advantages of domestic engineers, abundant clinical resources, and supportive policies [3]. - The innovative drug sector is transitioning from a follower to a leader in innovation, with domestic products expected to significantly participate in the global market over the next decade [3]. ETF Performance - The Hong Kong Stock Connect Innovative Drug ETF (520880) passively tracks the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, which focuses on the innovative drug industry chain [3]. - The index has shown a remarkable year-to-date increase of 101.58%, outperforming the Hang Seng Index and the Hang Seng Tech Index by 78.08 and 79.53 percentage points, respectively [6][7].

Core Viewpoint - The innovative drug sector is experiencing a rebound, with the Hong Kong Stock Connect Innovative Drug ETF (520880) showing a price increase of 1.36% on August 21, following two days of decline, indicating a positive market sentiment towards innovative pharmaceuticals [1][3]. Group 1: Market Performance - The Hong Kong Stock Connect Innovative Drug ETF (520880) recorded a trading volume of 2.78 billion yuan, reflecting strong investor interest [1]. - Key stocks in the innovative drug sector, such as King’s Ray Biotechnology and Lepu Biopharma, saw price increases of over 6%, while others like Livzon Pharmaceutical and Crystal Technology rose by more than 5% [1][2]. Group 2: Company Performance - Livzon Pharmaceutical reported a revenue of approximately 6.272 billion yuan for the first half of the year, a slight decrease of 0.17% year-on-year, but net profit increased by 9.4% to about 1.281 billion yuan [2]. - The company has 39 products in the research pipeline, with 13 in the registration phase and 4 in Phase III clinical trials, indicating a robust development strategy [2]. Group 3: Policy and Industry Outlook - Recent government initiatives emphasize enhancing high-quality technological supply and policy support for the biopharmaceutical industry, aiming to boost innovation and production of effective new drugs [3]. - China International Capital Corporation (CICC) expresses optimism about the long-term development of the innovative drug industry, highlighting the advantages of domestic engineering talent, rich clinical resources, and supportive policies [3]. - The innovative drug sector is transitioning into a 2.0 era, with expectations for significant participation in the global market over the next decade, supported by improved cash flow and R&D cycles [3]. Group 4: Index Performance - The Hang Seng Stock Connect Innovative Drug Select Index has seen a cumulative increase of 101.58% year-to-date as of July 31, significantly outperforming other indices [6]. - The index has shown exceptional performance compared to the Hang Seng Index and the Hang Seng Technology Index, exceeding their returns by 78.08 and 79.53 percentage points, respectively [6].

Core Viewpoint - The Hong Kong stock market for innovative drugs experienced a notable pullback, with the Hong Kong Innovative Drug ETF (520880) declining by 2.6% on August 19, despite a positive sentiment indicated by a real-time premium rate of 0.28% [1][3]. Group 1: Company Performance - China National Pharmaceutical Group reported a revenue of 17.57 billion yuan and a net profit of 3.39 billion yuan for the first half of the year, reflecting year-on-year growth of 10.7% and 140.2% respectively, marking three consecutive reporting periods of double-digit stable growth [3]. - The strong performance of China National Pharmaceutical Group was attributed to better-than-expected revenue growth from innovative products and dividend income [3]. Group 2: Market Trends - As of August 18, the Hong Kong Innovative Drug ETF (520880) tracked the Hang Seng Hong Kong Innovative Drug Selected Index, which has seen a year-to-date increase of 112.33%, significantly outperforming the Hang Seng Index (23.50%) and the Hang Seng Technology Index (22.05%) by 86.82 and 87.46 percentage points respectively [3]. - The adjustment in the market is viewed as a technical correction following a rapid increase, with long-term support expected from domestic policy and overseas value recognition for Chinese innovative drugs [3][6]. Group 3: Industry Outlook - The innovative drug industry is anticipated to undergo a value reassessment, supported by national policy and a clear trend of industry development and upgrading [5][6]. - The innovative drug sector is entering a 2.0 era, with domestic products gradually transitioning from following to leading innovation, benefiting from a favorable environment including engineer advantages, rich clinical resources, and supportive policies [6]. - The Hong Kong Innovative Drug ETF (520880) is the first ETF to passively track the Hang Seng Hong Kong Innovative Drug Selected Index, focusing on the innovative drug industry chain with a high concentration of leading stocks [6].

Group 1 - The Hang Seng Hong Kong Stock Connect Innovative Drug Selection Index (HSSCPB) increased by 0.77% as of August 15, 2025, with notable gains from companies such as BeiGene (1.78%) and Innovent Biologics (1.67%) [3] - The Hong Kong Innovative Drug Selection ETF (520690) rose by 0.60%, marking its third consecutive increase, with the latest price at 1.01 yuan [3] - Over the past week, the Hong Kong Innovative Drug Selection ETF has accumulated a rise of 2.76% [3] Group 2 - According to Guojin Securities, China's innovative drugs are on the rise, entering the initial phase of realizing innovation results, with significant opportunities for independent development and large-scale transactions in BD authorization [4] - In the oncology sector, two main directions are highlighted: the multidimensional iteration of ADC (antibody-drug conjugates) and innovations in the molecular components of immunotherapy [4] - The latest scale of the Hong Kong Innovative Drug Selection ETF reached 396 million yuan, a new high since its establishment [4] Group 3 - The top ten weighted stocks in the HSSCPB index account for 77.96% of the index, including companies like BeiGene and WuXi Biologics [5] - The Hong Kong Innovative Drug Selection ETF closely tracks the HSSCPB index, which reflects the performance of Hong Kong-listed companies involved in innovative drug research, development, and production [5]

Group 1 - The core viewpoint of the article highlights a significant pullback in the innovative drug sector, attributed to disappointing mid-term earnings and potential tariffs on imported drugs proposed by Trump, which have created market uncertainty [1] - Institutions believe the recent adjustment is a technical correction following a rapid increase, and they maintain a long-term positive outlook on the innovative drug sector due to domestic policy support and overseas value recognition [1][2] - The National Healthcare Security Administration's confirmation of a "first launch price mechanism" for new drugs is expected to provide higher pricing freedom and efficiency for high-quality innovative drugs, leading to faster cash flow returns for developers [1] Group 2 - Despite the recent market pullback, there has been a trend of increased investment, with the Hong Kong Stock Connect innovative drug ETF (520880) seeing a net inflow of 47.1 million yuan over four days and 715 million yuan over ten days [2] - The Hong Kong Stock Connect innovative drug ETF (520880) passively tracks the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, focusing on the innovative drug industry chain with a high concentration of leading stocks [4] - The Hang Seng Hong Kong Stock Connect Innovative Drug Select Index has outperformed other indices significantly, with a year-to-date increase of 101.58%, surpassing the Hang Seng Index and Hang Seng Technology Index by 78.08 and 79.53 percentage points, respectively [6]

Group 1 - The core viewpoint of the news is that the Hong Kong innovative drug ETF (520880) experienced a significant pullback, with a drop of nearly 4% during the morning session, despite strong buying interest as indicated by a substantial inflow of over 480 million yuan in the past five days [1][3] - The Hong Kong innovative drug ETF (520880) is the first ETF in the market tracking the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index, focusing on the innovative drug industry chain with a high concentration of leading companies [1][3] - Among the 29 leading innovative drug stocks covered by the ETF, only one stock, Jingtai Holdings, saw an increase, while others like Lepu Biopharma-B, CSPC Pharmaceutical Group, and others fell by over 7% [1][3] Group 2 - There are no significant negative factors affecting innovative drugs, and the short-term adjustment is largely influenced by market sentiment. Long-term support for the Chinese innovative drug market is expected from domestic medical insurance policies and overseas value recognition [3] - Recent policy support continues to be released, with the Shanghai Municipal Health Commission issuing measures to promote the high-quality development of commercial health insurance, which includes 18 initiatives aimed at expanding coverage for new medical technologies and drugs [3] - Dongwu Securities believes that under policy support, there is potential for a win-win situation among medical services, insurance, and pharmaceuticals, enhancing the accessibility and affordability of innovative drugs and devices [3] Group 3 - The Hong Kong innovative drug ETF (520880) has shown outstanding performance, with the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index rising by 101.58% year-to-date as of July 31, significantly outperforming the Hang Seng Index and Hang Seng Technology Index by 78.08 and 79.53 percentage points, respectively [3][4] - The historical performance of the Hang Seng Hong Kong Stock Connect Innovative Drug Select Index shows a decline in previous years, with annual returns of -22.72% in 2021, -16.48% in 2022, -19.76% in 2023, and -14.16% in 2024 [4]

Core Viewpoint - The Hong Kong stock market opened slightly lower on August 6, with innovative pharmaceuticals continuing to be active, particularly the high-profile Hong Kong Stock Connect innovative drug ETF (520880), which rose by 1.37% in early trading, aiming for a third consecutive daily gain [1]. Company Highlights - Crystal Tech Holdings (晶泰控股) announced a pipeline collaboration agreement with DoveTree, with a total order scale of approximately HKD 470 billion (USD 59.9 billion), marking one of the largest business development transactions in China's AI pharmaceutical sector by 2025 [2][3]. - Crystal Tech has received an initial payment of USD 51 million under the final agreement and is entitled to further payments of USD 49 million (to be paid within 180 days), as well as potential milestone payments of up to USD 5.89 billion based on regulatory and commercial achievements, along with royalties based on annual net sales [3]. Industry Trends - The National Medical Products Administration reported that 43 innovative drugs were approved in the first half of the year, a 59% year-on-year increase, nearing the total of 48 for the entire year of 2024 [3]. - According to China International Capital Corporation (中金公司), the long-term development trend of the innovative pharmaceutical industry is promising, supported by domestic engineering talent, abundant clinical resources, and favorable policies [3]. - The innovative drug sector is transitioning from a follower to a leader in innovation, with domestic products expected to significantly participate in the global market over the next decade [3]. Market Performance - The Hang Seng Stock Connect Innovative Drug ETF (520880) is the first ETF to passively track the Hang Seng Stock Connect Innovative Drug Select Index, focusing on the innovative drug industry chain with a high concentration of leading stocks [5]. - As of July 31, the Hang Seng Stock Connect Innovative Drug Select Index has risen by 101.58% year-to-date, outperforming the Hang Seng Index (23.50%) and the Hang Seng Technology Index (22.05%) by 78.08 and 79.53 percentage points, respectively [6].