香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因依賴該等內容而引致之任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B條作出。 茲載列本公司在上海證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 無錫藥明康德新藥開發股份有限公司 董事長 李革博士 香港，2025年12月15日 截至本公告日期，本公司董事會包括執行董事李革博士、陳民章博士、楊青博士及張朝暉先生； 非執行董事童小幪先生及吳亦兵博士；以及獨立非執行董事盧韶華女士、俞衛博士、張新博士、 詹智玲女士及冷雪松先生。 * 僅供識別 证券代码：603259 证券简称：药明康德 公告编号：临2025-073 无锡药明康德新药开发股份有限公司 关于出售资产进展公告 无锡药明康德新药开发股份有限公司董事会 2025 年 12 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並表明概不就因本公告全部或任何部份內容而產生或因倚賴 該等內容而引致的任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 有關出售附屬公司完成交割 的業務發展最新情況 茲提述無錫藥明康德新藥開發股份有限公司（「本公司」）日期為2025年10月24日 的公告（「該公告」），內容有關上海藥明出售而高瓴購買康德弘翼及津石醫藥 的所有股份。除非文意另有所指，否則本公告所用詞彙與該公告所定義詞彙具 有相同涵義。 截至本公告日期，上海藥明已收到高瓴按股權轉讓協議約定足額支付的第一 期轉讓對價人民幣15.4億元，股權轉讓協議約定的交割先決條件已滿足，本次 交易已完成交割，康德弘翼及津石醫藥不再納入本公司合併報表範圍。康德弘 翼及津石醫藥及其他相關各方將按股權轉讓協定約定辦理本次交易涉及康德 弘翼及津石醫藥的股權變更登記手續，並預計在2025年12月31日之前完成變更 登記。 經本公司財務部門按中 ...

Core Viewpoint - WuXi AppTec is accelerating the divestiture of non-core assets, focusing on its CRDMO (Contract Research, Development, and Manufacturing Organization) business model to enhance drug discovery, laboratory testing, and production services [5][10]. Summary by Sections Asset Sale - WuXi AppTec completed the sale of two subsidiaries for a total of 2.8 billion RMB, with a tax-adjusted net profit increase of approximately 960 million RMB expected [1][3]. - The subsidiaries, which contributed limited revenue, generated about 1.16 billion RMB in revenue, accounting for 3.5% of WuXi AppTec's total revenue for the same period [4][13]. Strategic Focus - The company aims to concentrate resources on its core CRDMO business, enhancing global capabilities and production capacity [4][10]. - Recent asset sales include the divestiture of various non-core businesses, such as clinical research and drug testing, to focus on high-value segments [6][14]. Financial Performance - WuXi AppTec reported a significant increase in profits, with total profit up 96.20% and net profit attributable to shareholders up 101.92% in the first half of 2025 [7][14]. - The revenue breakdown shows that chemical business revenue reached 16.30 billion RMB, a 33.51% increase, while other segments experienced declines [15][16]. Market Outlook - The global pharmaceutical R&D market is projected to grow from 260.6 billion USD in 2023 to 359.2 billion USD by 2028, with a compound annual growth rate (CAGR) of approximately 6.6% [9][17]. - The demand for integrated outsourcing services is expected to rise, particularly among small to medium-sized pharmaceutical companies lacking in-house capabilities [9][17].

Group 1 - Unicom Guowei has established a Central Research Institute focusing on the development of edge AI chips for applications in autonomous driving, embodied robots, and low-altitude flying vehicles [2] - The research will also include new types of storage devices based on two-dimensional materials and high-performance special sensor chips [2] - Aerospace Electronics plans to increase its investment in Aerospace Long March Rocket Technology Co., Ltd. by 728 million yuan, maintaining the existing shareholding structure [3] Group 2 - Aerospace Rainbow successfully completed the first flight test of its self-developed Rainbow-7 high-altitude, high-speed, long-endurance drone, achieving all preset parameters [4] - The project is still in the research and testing phase, with further rigorous testing and validation required before mass production [4] Group 3 - Changchun High-tech's subsidiary signed an exclusive licensing agreement for the GenSci098 injection project, potentially earning up to 1.365 billion USD in milestone payments [5] - The agreement includes an initial payment of 120 million USD and additional milestone payments related to development and commercialization [5] Group 4 - TCL Technology plans to acquire a 10.7656% stake in Shenzhen Huaxing Semiconductor for 6.045 billion yuan, increasing its ownership from 84.2105% to 94.9761% [26] - This acquisition aims to enhance TCL's competitiveness and profitability in the semiconductor display industry [26] Group 5 - Zhongmin Resources announced the successful ignition of its Tsumeb smelting plant's multi-metal comprehensive recycling project, with an annual processing capacity of 80,000 tons [11] - The project will produce various products, including germanium ingots and zinc ingots, with a design capacity of 33 tons/year for germanium [11] Group 6 - Xinhua Insurance reported a 16% year-on-year increase in original insurance premium income, totaling 188.85 billion yuan from January to November 2025 [43] - This growth reflects the company's strong performance in the insurance market [43]

Core Viewpoint - WuXi AppTec announced the completion of a transaction involving the sale of 100% equity in two subsidiaries for a total consideration of 2.8 billion yuan, which is expected to generate a net profit of approximately 960 million yuan, representing over 10% of the company's audited net profit for the fiscal year 2024 [1] Group 1 - The company’s wholly-owned subsidiary, Shanghai WuXi AppTec New Drug Development Co., Ltd., transferred its holdings in Shanghai Kangde Hongyi Medical Clinical Research Co., Ltd. and Shanghai WuXi Jinshi Pharmaceutical Technology Co., Ltd. [1] - The first payment of 1.54 billion yuan has been received from the acquirers, and the transaction has been completed with the target companies no longer included in the company’s consolidated financial statements [1] - The transaction is subject to the fulfillment of various agreements outlined in the equity transfer agreement by all parties involved [1]

证券代码：603259 证券简称：药明康德 公告编号：临2025-073 无锡药明康德新药开发股份有限公司 关于出售资产进展公告 二、交易进展 截至本公告日，转让方已收到受让方按《股权转让协议》约定足额支付的第 一期股权转让价款人民币 15.4 亿元，《股权转让协议》约定的交割先决条件已 满足，本次交易已完成交割，目标公司不再纳入公司合并报表范围。目标公司及 相关各方将按《股权转让协议》约定办理本次交易涉及的目标公司的市监局变更 登记手续，预计 2025 年 12 月 31 日之前完成变更登记。 经公司财务部门按中国企业会计准则初步核算，截至本公告日本次交易预计 产生税后净利润约 9.6 亿元，占公司最近一期（2024 年度）经审计归母股东净利 润的比例超过 10%。公司将根据中国企业会计准则与国际财务报告准则等有关需 适用的规定对投资收益进行会计处理，具体影响金额以注册会计师年度审计确认 后的结果为准。后续各方仍需继续履行《股权转让协议》项下的各项约定。敬请 投资者注意投资风险。 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任 ...

Group 1 - BlackRock's long position in Wuxi AppTec Co., Ltd. H-shares decreased from 5.24% to 4.57% as of December 9, 2025 [1]

Core Viewpoint - The revised version of the Biological Safety Act has been incorporated into the National Defense Authorization Act (NDAA) for fiscal year 2026, marking a significant legislative step since its introduction in 2024 [2]. Group 1: Legislative Changes - The revised act eliminates direct naming of specific companies, such as WuXi AppTec and BGI, and instead allows the White House and the Office of Management and Budget (OMB) to create a dynamic list of "biotechnology companies of concern" within one year after the act's passage [3]. - A three-year grace period is established for existing contracts to avoid immediate impacts, and Medicare Part B is explicitly exempted from restrictions, reducing opposition from large pharmaceutical companies [3]. - The act limits its scope to contracts governed by the Federal Acquisition Regulation (FAR), excluding commercial retail or non-federal funding transactions [3]. Group 2: Immediate and Long-term Implications - The removal of direct naming helps avoid "labeling" companies, providing them time to adjust their supply chains, while the grace period and existing contract exemptions lessen the act's immediate impact on current operations [4]. - However, long-term risks remain as the dynamic list created by the OMB may still include Chinese companies, which would prevent them from participating in federal direct procurement contracts [4]. - The core aim of the act is to "cut off federal funding to identified 'biotechnology companies of concern'," which could still affect Chinese firms due to potential associations with foreign adversaries [4]. - The act may trigger a ripple effect, leading to restrictions on Chinese companies in other sectors, such as medical IT and biological data [4].

Core Viewpoint - WuXi AppTec announced the completion of the equity transfer of its subsidiary, with an initial payment of 1.54 billion yuan, resulting in a significant impact on the company's financials [1] Group 1: Transaction Details - The equity transfer agreement has been fulfilled, and the transaction has been completed, leading to the target company being excluded from the consolidated financial statements of WuXi AppTec [1] - The expected after-tax net profit from this transaction is approximately 960 million yuan, which represents over 10% of the company's latest audited net profit attributable to shareholders for the fiscal year 2024 [1] Group 2: Future Actions - The target company and related parties will proceed with the registration changes as stipulated in the agreement, with an expected completion date before December 31, 2025 [1]

Investment Rating - The report maintains an "Outperform" rating for several companies in the innovative drug and medical device industry, including Jiangsu Heng Rui Medicine, Hansoh Pharmaceutical Group, 3SBio, Sichuan Kelun Pharmaceutical, and Jiangsu Nhwa Pharmaceutical [5][6][25]. Core Insights - The report emphasizes the high prosperity in innovative drugs and continues to recommend companies with innovative pipelines that are entering a volume increase phase, maintaining "Outperform" ratings for various Biopharma/Biotech companies [5][25]. - The National Healthcare Security Administration announced the 2025 insurance drug list, which added 114 drugs, including 50 innovative drugs, further validating insurance support for innovation and indicating promising domestic demand [26][27]. Summary by Sections 1. Continuous Recommendation of Innovative Drugs and Industry Chain - The report highlights the ongoing recommendation of innovative drugs and the industry chain, with a focus on companies expected to see a revaluation due to their innovative pipelines [5][25]. - Specific companies mentioned include WuXi AppTec, WuXi XDC Cayman, Hangzhou Tigermed Consulting, and leading medical equipment companies like Beijing Chunlizhengda Medical Instruments and Lepu Medical, all rated "Outperform" [5][25]. 2. Performance of A-Shares Pharmaceutical Sector - In the second week of December 2025, the A-Shares pharmaceutical sector underperformed the market, with the SW Pharma and Biotech index falling by 1.0% compared to a 0.3% decline in the SHCOMP [8][27]. - The report notes that the premium level of the pharmaceutical sector relative to all A-Shares is at a normal level, with a current relative premium rate of 69.8% [16][27]. 3. Performance of Hong Kong and U.S. Pharmaceutical Sectors - The Hong Kong stock pharmaceutical sector underperformed the market, with the Hang Seng Healthcare index falling by 2.3%, while the U.S. stock pharmaceutical sector outperformed, with the S&P 500 Healthcare Select Sector Index rising by 0.4% [28][27].