证券代码：600538 证券简称：国发股份 公告编号：临 2023-028 北海国发川山生物股份有限公司 关于召开 2022 年度业绩说明会的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 会议召开时间：2023 年 5 月 19 日(星期五)下午 15:00-16:30 会 议 召 开 地 点 ： 上海证券 交 易 所 上 证 路 演 中 心 （ 网址： http://roadshow.sseinfo.com/） 会议召开方式：上证路演中心视频直播和网络互动 三、参加人员 投资者可于 2023 年 5 月 13 日(星期六)至 5 月 18 日(星期四)16:00 前登 录上证路演中心网站首页点击"提问预征集"栏目或通过公司邮箱 securities@gofar.com.cn 进行提问。公司将在说明会上对投资者普遍关注的 问题进行回答。 北海国发川山生物股份有限公司（以下简称"公司"）已于 2023 年 4 月 18 日发布公司 2022 年度报告，为便于广大投资者更全面深入地了解公司 2022 年 度 ...

Financial Performance - The company's operating revenue for Q1 2023 was ¥101,579,609.22, representing a decrease of 15.94% compared to the same period last year[3] - The net profit attributable to shareholders of the listed company was -¥2,646,847.55, a decline of 135.74% year-on-year[3] - The net profit attributable to shareholders after deducting non-recurring gains and losses was -¥3,089,888.09, down 144.02% from the previous year[3] - The basic earnings per share were -¥0.005, reflecting a decrease of 150.00% compared to the same period last year[3] - Net profit for Q1 2023 was a loss of ¥2,122,373.30, compared to a profit of ¥8,064,707.43 in Q1 2022, representing a significant decline[19] - The total comprehensive income attributable to the parent company was -2,646,847.55 CNY, compared to 7,406,463.37 CNY in the previous year[21] - The total comprehensive income for the period was -2,122,373.30 CNY, compared to 8,064,707.43 CNY in the previous year[21] Assets and Liabilities - The total assets at the end of the reporting period were ¥1,137,985,078.15, a decrease of 0.36% from the end of the previous year[4] - The company's total assets as of the end of Q1 2023 were ¥1,137,985,078.15, slightly down from ¥1,142,144,892.25 at the end of Q1 2022[17] - Total liabilities decreased to ¥180,127,941.32 in Q1 2023 from ¥182,165,382.12 in Q1 2022[17] - The total equity attributable to shareholders was ¥948,917,777.86 as of the end of Q1 2023, down from ¥951,564,625.41 in Q1 2022[17] Cash Flow - The company reported a net cash flow from operating activities of -¥29,405,928.68, which is not applicable for year-on-year comparison[3] - The net cash flow from operating activities was -29,405,928.68 CNY, a decline from -20,497,876.54 CNY year-over-year[21] - Cash inflow from operating activities totaled 85,107,320.59 CNY, down from 93,457,528.34 CNY in the same quarter last year[21] - The company’s cash and cash equivalents decreased from RMB 170,858,268.06 at the end of 2022 to RMB 147,578,019.16 as of March 31, 2023, representing a decline of approximately 13.6%[15] - Cash and cash equivalents at the end of the period were 126,184,836.92 CNY, down from 161,951,203.59 CNY at the end of the previous year[22] - The company received 10,000,000.00 CNY from investment recoveries during the quarter[22] - Total cash inflow from financing activities was 1,800,000.00 CNY, compared to 1,700,000.00 CNY in the previous year[22] - The company paid 366,127.64 CNY in cash outflows related to financing activities, down from 795,737.35 CNY year-over-year[22] Investments and Expenses - The company's investment in the Nanjing Huada Gongying No. 1 Venture Capital Partnership resulted in a loss increase of ¥3,665,800 due to the decline in stock prices of its listed projects[5] - The full subsidiary, Guangzhou Gaosheng Biotechnology Co., Ltd., experienced a decrease in executable contract amounts and gross profit margins, leading to a profit reduction of ¥5,974,500[6] - Research and development expenses for Q1 2023 were ¥1,664,937.32, an increase from ¥1,545,822.43 in Q1 2022[19] - The company reported an investment loss of ¥6,297,784.29 in Q1 2023, compared to a loss of ¥2,495,849.45 in Q1 2022[19] Shareholder Information - Shareholder Pan Libin has reduced his holdings by 665,100 shares, with a total reduction plan of up to 2.58 million shares[12] - The company’s major shareholders, Zhu Rongjuan and Peng Tao, hold a combined total of 107,673,242 shares, representing 20.55% of the total share capital, which are currently under judicial freeze[13] Strategic Plans - The company is enhancing market promotion and increasing internal discussions to adapt to new economic conditions, resulting in higher expenses[6] - The company plans to continue expanding its market presence and product offerings through strategic investments and partnerships[11] - The company's management indicated a focus on cost control and efficiency improvements in future operations[20]

Financial Performance - In 2022, the net profit attributable to shareholders was CNY 34.8612 million, with a cumulative distributable profit of CNY -390.4095 million at the end of the year[5]. - The company proposed no profit distribution for 2022 due to negative cumulative undistributed profits, failing to meet the cash dividend requirements[5]. - The company's operating revenue for 2022 was CNY 459,684,048.23, an increase of 8.23% compared to CNY 424,717,057.51 in 2021[18]. - The net profit attributable to shareholders for 2022 reached CNY 34,861,170.21, representing a significant increase of 232.44% from CNY 10,486,532.83 in 2021[18]. - The basic earnings per share for 2022 was CNY 0.07, up 250.00% from CNY 0.02 in 2021[19]. - The weighted average return on equity increased to 3.73% in 2022, up by 2.53 percentage points from 1.20% in 2021[19]. - The total assets of the company at the end of 2022 were CNY 1,142,144,892.25, a growth of 5.48% from CNY 1,082,774,790.94 at the end of 2021[18]. - The company reported a cash flow from operating activities of -CNY 15,741,511.89 for 2022, compared to -CNY 6,338,055.40 in 2021, indicating a worsening cash flow situation[18]. Investments and Subsidiaries - The company confirmed an investment income of CNY 13,034,400 from its 27.03% stake in Nanjing Huada Gongying No. 1 Venture Capital Partnership in 2022[19]. - The company invested 20 million RMB in Miracle Medicine Technology, establishing a long-term strategic partnership to promote mutual development[30]. - GaoSheng Bio, a subsidiary, reported a full-year revenue of 197 million RMB in 2022, a year-on-year growth of 10.78%, and a net profit of 38.49 million RMB, increasing by 20.74% compared to the previous year[25]. - The company confirmed an investment income of 13.03 million RMB from the Nanjing Huada Gongying No. 1 Investment Fund in 2022, which has successfully exited two projects that went public[28]. Market and Industry Trends - The pharmaceutical manufacturing industry in China faced challenges in 2022, with a 1.6% decline in revenue for large-scale enterprises, totaling 2.91 trillion RMB, and a 31.8% drop in total profit[31]. - The pharmaceutical circulation market in China showed steady growth, with a total sales volume of 2.6064 trillion RMB in 2021, reflecting an 8.5% year-on-year increase[32]. - The average profit margin in the pharmaceutical circulation sector decreased to 1.7% in 2021, indicating a trend towards lower profitability[32]. - The overall demand in the pharmaceutical industry is characterized by rigidity, with limited impact from macroeconomic fluctuations, indicating a stable market environment[48]. Operational Management - The company plans to continue expanding its market presence and enhancing operational management through its subsidiary, Guangzhou Gaosheng Biotechnology Co., Ltd.[19]. - The company actively expanded its market presence, increasing the number of automatic extraction detection workstations launched in 2022 by 6 units compared to the previous year[26]. - The company is focusing on the development of innovative products in the in vitro diagnostics sector, driven by increasing medical consumption levels and supportive national policies[37]. - The company is advancing its logistics capabilities by optimizing network layouts and enhancing service capabilities, particularly in rural areas[35]. Governance and Compliance - The company’s financial report has been audited by Tianjian Accounting Firm, which issued a standard unqualified opinion audit report[4]. - The company has established a cooperative model for medical imaging and radiotherapy centers, utilizing large medical equipment and providing technical support, with ongoing projects like the Jiangsu Suqian Imaging Center[45]. - The company has implemented a comprehensive internal control system that meets the requirements of relevant regulatory bodies, ensuring effective operation and compliance[150]. - The company has not reported any significant internal control deficiencies during the reporting period[151]. Environmental Responsibility - In 2022, the company invested 17.46 million yuan in environmental protection initiatives[154]. - The total wastewater discharge in 2022 was 36,636 tons, with biochemical oxygen demand (BOD) emissions of 252.788 kg and chemical oxygen demand (COD) emissions of 989.172 kg[155]. - The company has not reported any significant changes in research and development investment or major projects during the reporting period[90]. - The company has not faced any administrative penalties related to environmental issues during the reporting period[155]. Employee and Management Structure - The company has a board of directors consisting of 9 members, including 3 independent directors, ensuring a balanced governance structure[118]. - The total number of employees in the parent company is 179, while the main subsidiaries employ 322, resulting in a total of 501 employees[142]. - The company's salary structure consists of basic salary (20%), position salary (50-60%), performance salary (20-30%), and allowances[143]. - The company encourages employee training and development through various programs to enhance professional skills and knowledge[144]. Future Outlook - The company plans to achieve a sales revenue of no less than 470 million yuan in 2023, indicating a focus on sustained profit growth[106]. - The company is focusing on optimizing budget management and reducing financial risks through effective accounts receivable management[109]. - The company is committed to ongoing research and development to innovate new products and technologies[128]. - Future outlook includes potential market expansion and strategic acquisitions to drive growth[128].

北海国发川山生物股份有限公司 2022 年第三季度报告 证券代码：600538 证券简称：国发股份 北海国发川山生物股份有限公司 2022 年第三季度报告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真实、准确、完整， 不存在虚假记载、误导性陈述或重大遗漏，并承担个别和连带的法律责任。 (一)主要会计数据和财务指标 1 / 12 单位：元 币种：人民币 项目 本报告期 本报告期比上 年同期增减变 动幅度(%) 年初至报告期末 年初至报告期末 比上年同期增减 变动幅度(%) 营业收入 119,167,316.64 4.05 338,428,175.18 11.09 归属于上市公司股东的净利润 24,128,757.20 654.21 32,850,494.10 320.93 归属于上市公司股东的扣除非 经常性损益的净利润 24,081,678.05 759.87 31,830,274.16 352.11 经营活动产生的现金流量净额 -14,257, ...

Financial Performance - The company's operating revenue for the first half of 2022 was CNY 219,260,858.54, representing a 15.34% increase compared to CNY 190,098,259.43 in the same period last year[17]. - The net profit attributable to shareholders of the listed company reached CNY 8,721,736.90, an increase of 89.39% from CNY 4,605,070.88 in the previous year[17]. - The net profit attributable to shareholders after deducting non-recurring gains and losses was CNY 7,748,596.11, up 82.76% from CNY 4,239,797.10 in the same period last year[17]. - The basic earnings per share for the first half of 2022 was CNY 0.02, doubling from CNY 0.01 in the same period last year[18]. - The weighted average return on net assets increased to 0.95% from 0.54% in the previous year, reflecting improved profitability[18]. - The company achieved operating revenue of CNY 219.26 million in the first half of 2022, representing a year-on-year growth of 15.34%[41]. - The net profit attributable to shareholders was CNY 8.72 million, an increase of 89.39% compared to the same period last year[41]. Assets and Liabilities - The company's total assets at the end of the reporting period were CNY 1,082,491,905.11, a slight decrease of 0.03% compared to CNY 1,082,774,790.94 at the end of the previous year[17]. - The net assets attributable to shareholders of the listed company increased by 0.95% to CNY 925,425,192.10 from CNY 916,703,455.20 at the end of the previous year[17]. - Accounts receivable increased by 19.93% to CNY 233.52 million, indicating improved sales performance[47]. - Short-term borrowings rose by 93% to CNY 1.93 million, reflecting the need for additional working capital[48]. - The company's total liabilities increased, with accounts payable rising from ¥49,639,558.59 to ¥65,165,350.11, an increase of approximately 31.2%[110]. Market and Industry Insights - The company operates in the wholesale industry, specifically in pharmaceutical manufacturing and distribution, with a focus on regions such as Guangxi, Guangdong, Beijing, Chongqing, Jiangsu, and Shenzhen[22][23]. - The pharmaceutical industry is characterized by inelastic demand, showing resilience against macroeconomic fluctuations[30]. - The company emphasizes a strong market competitive advantage through extensive regional coverage and delivery capabilities[30]. - Seasonal sales fluctuations are noted, particularly during the Chinese New Year, affecting overall sales performance[30]. - The pharmaceutical manufacturing industry in China achieved operating revenue of CNY 1,400.78 billion, a decrease of 0.6% year-on-year, while operating costs increased by 10.3% to CNY 815.96 billion, resulting in a total profit of CNY 220.95 billion, down 27.6% year-on-year[31]. Subsidiaries and Business Segments - The company has a stable customer base with 7 direct stores, 53 franchise stores, and 4 licensed franchise stores in the North Bay area[27]. - The company’s subsidiary, Beijing Xiangya Medical Technology Co., focuses on molecular imaging and remote medical services, utilizing large medical equipment in collaboration with medical institutions[28]. - The DNA testing business under subsidiary GaoSheng Bio provides comprehensive solutions, including DNA extraction, amplification, and sequencing services[29]. - The subsidiary, Gaoseng Bio, completed 60.55% of its committed performance for the first half of 2022[41]. Research and Development - Research and development expenses increased by 12.21% to CNY 3.35 million compared to the previous year[46]. - The core technology advantage of the company in forensic DNA testing has been recognized with a first-class award in the Guangdong Provincial Science and Technology Progress Award for its automated DNA extraction technology[39]. Risks and Challenges - The company faces risks from industry policy changes, including the impact of national medical reforms and increased competition, necessitating timely adjustments in business strategies[54]. - Increased operational costs due to stricter environmental regulations and rising material costs pose additional risks to the company's profitability[60]. - The company faced significant challenges due to the ongoing COVID-19 pandemic, with disruptions in product delivery and increased costs in raw materials, labor, and logistics[61]. Environmental and Social Responsibility - The total wastewater discharge in the first half of 2022 was 8,716 tons, with chemical oxygen demand emissions of 78.444 kg and biochemical oxygen demand emissions of 22.662 kg[70]. - The company reported a total of 85.5 tons of general solid waste generated in the first half of 2022, including 66.24 tons of medicinal residue and 5.78 tons of cardboard[71]. - The company donated a total of RMB 180,000 worth of medical supplies to various hospitals in Beihai to support COVID-19 prevention efforts[91]. Shareholder and Equity Information - The actual controller and shareholders are restricted from transferring newly issued shares for 12 months post-issuance, effective until May 30, 2023[74]. - The largest shareholder, Zhu Rongjuan, holds 90,400,542 shares, accounting for 17.25% of total shares, with 66,500,000 shares pledged[99]. - The company has a total of 7 subsidiaries included in the consolidated financial statements[135]. Financial Reporting and Compliance - The financial statements of the company comply with accounting standards, accurately reflecting its financial position and operating results[139]. - The company’s financial statements are prepared based on the assumption of continuous operation[136]. - The company follows specific accounting methods for mergers and acquisitions, recognizing goodwill when the purchase cost exceeds the fair value of identifiable net assets[143].

Financial Performance - The company's operating revenue for Q1 2022 was CNY 120,839,345.28, representing a year-on-year increase of 28.53%[5] - The net profit attributable to shareholders for the same period was CNY 7,406,463.37, reflecting a significant increase of 74.53% compared to the previous year[5] - The net profit attributable to shareholders after deducting non-recurring gains and losses was CNY 7,019,309.23, up by 71.22% year-on-year[5] - The basic earnings per share for Q1 2022 was CNY 0.01, an increase of 25.00% from the same period last year[5] - Net profit for Q1 2022 reached CNY 8,064,707.43, representing a 114.5% increase from CNY 3,759,348.37 in Q1 2021[19] - The company reported a gross profit margin of approximately 10.1% for Q1 2022, compared to 10.1% in Q1 2021[18] Assets and Liabilities - The total assets at the end of the reporting period were CNY 1,084,923,898.28, showing a slight increase of 0.20% from the end of the previous year[5] - The company's current assets totaled RMB 517,104,524.31 as of March 31, 2022, up from RMB 508,824,738.93 at the end of 2021, reflecting a growth of approximately 1.5%[14] - Total liabilities decreased to RMB 154,045,045.33 from RMB 160,160,645.42, a reduction of approximately 3.8%[16] - The company's equity attributable to shareholders increased to RMB 924,109,918.57 from RMB 916,703,455.20, reflecting a growth of about 0.2%[16] Cash Flow - The net cash flow from operating activities was negative at CNY -20,497,876.54, indicating a significant cash outflow[5] - The net cash flow from operating activities for Q1 2022 was -CNY 20,497,876.54, an improvement from -CNY 28,765,844.61 in Q1 2021[22] - Cash and cash equivalents decreased to RMB 169,273,773.04 from RMB 190,402,776.13, representing a decline of about 11.1%[14] - Cash and cash equivalents at the end of Q1 2022 totaled CNY 161,951,203.59, compared to CNY 138,263,129.46 at the end of Q1 2021[23] - The company experienced a net cash outflow from investing activities of CNY 4,506,760.17 in Q1 2022, compared to an outflow of CNY 34,898,373.96 in Q1 2021[23] Shareholder Information - The total number of ordinary shareholders at the end of the reporting period was 38,293[8] - The largest shareholder, Zhu Rongjuan, held 90,400,542 shares, representing 17.25% of the total shares, with a portion pledged[9] - The company had 12,427,005 shares of restricted stock released for trading on January 28, 2022[11] Operating Costs and Expenses - Total operating costs for Q1 2022 were CNY 108,396,295.24, up 22.8% from CNY 88,261,627.56 in Q1 2021[18] - Research and development expenses for Q1 2022 were CNY 1,545,822.43, slightly down from CNY 1,634,607.66 in Q1 2021[18] - The company recorded an investment loss of CNY 2,495,849.45 in Q1 2022, compared to a loss of CNY 782,493.86 in Q1 2021[18] Equity and Return Metrics - The weighted average return on equity increased by 0.30 percentage points to 0.80%[5] - Basic and diluted earnings per share for Q1 2022 were both CNY 0.01, unchanged from Q1 2021[19] Accounts Receivable and Inventory - Accounts receivable increased significantly to RMB 230,926,549.99 from RMB 194,704,331.66, marking an increase of approximately 18.6%[14] - Inventory rose to RMB 82,354,705.86 from RMB 73,192,654.70, indicating an increase of about 12.5%[14]

Financial Performance - The net profit attributable to shareholders for 2020 was CNY 3,200,573.27, with a cumulative profit available for distribution at the end of 2020 being CNY -435,757,212.81[5] - The company's capital reserve at the end of 2020 was CNY 735,508,718.82[5] - The company will not distribute profits or increase capital reserves for the year 2020 due to negative cumulative undistributed profits[5] - The company's operating revenue for 2020 was CNY 267,699,833.56, representing a 6.59% increase compared to CNY 251,153,525.23 in 2019[19] - The net profit attributable to shareholders decreased by 44.56% to CNY 3,200,573.27 from CNY 5,772,938.14 in the previous year[19] - The net cash flow from operating activities improved significantly to CNY 26,844,785.64, compared to a negative cash flow of CNY -5,442,980.17 in 2019[19] - The total assets increased by 42.09% to CNY 1,065,713,192.47 at the end of 2020, up from CNY 750,047,508.16 in 2019[19] - The company's net assets attributable to shareholders rose by 30.79% to CNY 844,417,226.94 from CNY 645,608,650.70 in the previous year[19] - Basic earnings per share decreased by 41.67% to CNY 0.007 in 2020, down from CNY 0.012 in 2019[20] - The weighted average return on net assets was 0.49%, a decrease of 0.41 percentage points from 0.90% in 2019[20] - The company reported a significant increase in net profit after deducting non-recurring gains, reaching CNY 1,667,096.30, compared to a loss of CNY -10,728,072.87 in 2019[19] - The fourth quarter of 2020 saw the highest quarterly revenue of CNY 86,358,044.86, contributing to a recovery in profitability[23] Acquisitions and Investments - The company completed the acquisition of Gaosheng Biology, which contributed to the increase in total assets and net assets[21] - The acquisition of Gaosong Biological was completed on December 23, 2020, and its balance sheet was included in the consolidated financial statements, although its income statement was not[29] - The company acquired 99.9779% of Gaosheng Biological for a total transaction amount of 355.6932 million RMB, with cash consideration of 158.1597 million RMB and share consideration of 197.5336 million RMB[46] - The company completed the acquisition of GaoSheng Bio, enhancing its sustainable development capabilities and entering the in vitro diagnostic industry[53] - The company has established a joint venture, Shanghai Hanhu Bio-pharmaceutical Co., Ltd., with a registered capital of RMB 30 million, in which the company holds a 15% stake[167] - The company acquired an additional 50% stake in Guangdong Gaosong Forensic Technology Co., Ltd., increasing its ownership to 100% and changing the company's name to Guangdong Gaosong Information Technology Co., Ltd.[182] Operational Risks and Management - There were no significant risks that materially affected the company's operations during the reporting period[6] - The company has not engaged in non-operational fund occupation by controlling shareholders or related parties[6] - The company has not violated decision-making procedures for external guarantees[6] - The company has detailed various operational risks and corresponding countermeasures in the report[6] - The integration of GaoSheng Bio's management and financial systems is ongoing, with plans to optimize internal controls and improve management levels in 2021[54] - The company aims to enhance internal control systems to ensure legal and compliant operations[126] - The company will optimize management and control systems to improve operational efficiency and decision-making processes[130] Market and Industry Trends - The pharmaceutical industry is characterized by inelastic demand, with limited cyclical fluctuations, and the company benefits from strong regional distribution capabilities[39] - The ongoing national medical reform and cost control measures are pressuring pharmaceutical companies to shift towards high-quality development[45] - The medical industry is expected to grow due to economic recovery and increased health awareness post-COVID-19, despite challenges from price procurement policies[119] - The forensic DNA testing industry is experiencing rapid growth, with judicial identification cases increasing approximately 7.85 times from 2005 to 2018, with a CAGR of 17.91%[122] Social Responsibility and Environmental Impact - The company emphasizes maintaining shareholder rights and has established a comprehensive internal control system to protect the interests of all shareholders[185] - The company actively engages in social responsibility initiatives, particularly in response to the COVID-19 pandemic[186] - The company has implemented a clean production and energy management strategy to enhance its environmental responsibility[186] - The company donated a total of 150,000 bottles of 100ML ethanol disinfectant to various hospitals for COVID-19 prevention efforts[186] - The company reported a total wastewater discharge of 42,164 tons in 2020, with biochemical oxygen demand (BOD) emissions of 105.41 kg and chemical oxygen demand (COD) emissions of 421.64 kg[188] Shareholder and Dividend Policies - The company has a commitment from shareholders regarding the lock-up period for newly issued shares, which lasts for 12 months from the completion of the issuance[148] - The cash dividend policy stipulates that the company should distribute at least 30% of the average distributable profit over the last three years if there are positive retained earnings[145] - The company has not proposed any cash profit distribution plans despite having positive profits available for distribution to ordinary shareholders[147] - The cash dividend distribution is contingent upon the company having positive retained earnings and not planning significant investments or cash expenditures[145] Financial Reporting and Audit - The company received a standard unqualified audit report from Tianjian Accounting Firm[4] - The company appointed Tianjian Accounting Firm for the 2020 financial statement audit, with an audit fee of RMB 400,000[161] - The company executed the new revenue recognition standard starting January 1, 2020, impacting the financial statements without adjusting prior periods[158] - The company has no significant accounting errors or changes in accounting policies that would affect the financial statements[159] Research and Development - Research and development expenses decreased by 33.66% compared to the previous year, amounting to 50,134 RMB[59] - The company’s research and development expenses totaled CNY 50,133.53, accounting for 0.02% of total revenue, with a decrease in R&D investment compared to the previous year[69][70] Customer and Sales Performance - The company has established a stable customer base with 7 direct stores and 58 franchise stores in the North Bay area[35] - The company achieved operating revenue of 268 million RMB in 2020, with pharmaceutical manufacturing sales accounting for 15.11% and pharmaceutical distribution sales for 74.27% of total sales[31] - The sales revenue for ethanol disinfectant in 2020 amounted to 22.67 million yuan[100] - The company’s revenue from ophthalmic drugs (Pearl Eye Drops) decreased by 44.4% compared to the previous year, with a gross margin of 69.84%[104] - The revenue from gastrointestinal drugs (Gastrointestinal Ning Granules) decreased by 15.18%, with a gross margin of -39.27%[104]

Financial Performance - The net profit attributable to shareholders for 2021 was CNY 10,486,532.83, with a cumulative profit available for distribution to investors at the end of 2021 being CNY -425,270,679.98[6] - The company has proposed not to distribute profits for the year 2021 due to negative retained earnings, which does not meet the conditions for cash dividends[6] - The company's operating revenue for 2021 was CNY 424,717,057.51, representing a year-on-year increase of 58.65% compared to CNY 267,699,833.56 in 2020[22] - The net profit attributable to shareholders for 2021 was CNY 10,486,532.83, a significant increase of 227.65% from CNY 3,200,573.27 in 2020[22] - The net profit after deducting non-recurring gains and losses was CNY 7,021,239.21, up 321.17% from CNY 1,667,096.30 in 2020[22] - The company's total assets at the end of 2021 were CNY 1,082,774,790.94, reflecting a 1.60% increase from CNY 1,065,713,192.47 at the end of 2020[22] - The basic earnings per share for 2021 was CNY 0.02, an increase of 185.71% compared to CNY 0.007 in 2020[23] - The weighted average return on equity for 2021 was 1.20%, an increase of 0.71 percentage points from 0.49% in 2020[23] - The company reported a cash flow from operating activities net amount of CNY -6,338,055.40 for 2021, a decrease of 123.61% from CNY 26,844,785.64 in 2020[22] - The company achieved a sales revenue of 425 million RMB in 2021, representing a year-on-year increase of 58.65%[55] - The net profit attributable to shareholders reached 10.49 million RMB, up 227.65% compared to the previous year[55] - The net profit after deducting non-recurring gains and losses was 7.02 million RMB, reflecting a growth of 321.17% year-on-year[55] Acquisitions and Investments - The company completed the acquisition of GaoSheng Bio's equity at the end of 2020, which significantly contributed to the revenue and profit in 2021[24] - The company completed the acquisition of Guangzhou Gaoshen Bio, successfully implementing a major asset restructuring, raising 68.1 million RMB through a private placement of 12,427,005 shares[31] - The company invested 100 million RMB in the BGI Win-Win Fund, receiving a distribution of 4.7195 million RMB during the reporting period[32] - The company invested in the development of an automated micro DNA extraction and detection centrifuge module, completing the R&D and production launch in November 2021[76] - The company is focusing on strategic mergers and acquisitions to accelerate industry integration and resource complementarity[121] Market and Industry Trends - The pharmaceutical manufacturing industry in China achieved a revenue of 2,928.85 billion RMB in 2021, with a year-on-year growth of 20.1%[35] - The domestic in vitro diagnostic market reached a scale of 89 billion RMB in 2020, driven by technological innovation and increasing healthcare spending[40] - The pharmaceutical retail market in China was valued at 511.9 billion RMB in 2020, with a year-on-year growth of 10.1%[38] - The company is responding to significant policy changes in the pharmaceutical industry, including the institutionalization of volume-based procurement and the ongoing evaluation of generic drug consistency[83] Operational Efficiency and Internal Control - The company actively managed its internal control systems and governance structures, revising 10 internal regulations to enhance compliance and operational efficiency[34] - The company has established a mature supplier selection and review mechanism for raw materials, ensuring compliance with GMP standards[44] - The company has implemented a performance evaluation mechanism for senior management, linking compensation to annual performance[172] - The company has established a reasonable internal control system that meets the requirements of the Ministry of Finance and the China Securities Regulatory Commission, ensuring effective management and development[174] Governance and Compliance - The company maintains a strict governance structure in compliance with the Company Law and relevant regulations, ensuring clear responsibilities among shareholders, the board of directors, and the supervisory board[141] - The board of directors consists of 9 members, including 3 independent directors, and operates under established rules to ensure democratic and scientific decision-making[142] - The supervisory board, comprising 3 members, actively supervises the board's operations and financial activities to protect shareholder interests[143] - The company emphasizes investor relations, utilizing multiple channels to engage with shareholders and protect the rights of minority shareholders[143] Research and Development - Research and development expenses increased to 9.14 million RMB, a substantial rise of 18,139.04% year-on-year, primarily due to GaoSheng Bio's R&D investments[57] - The company is responding to the increasing demand for precision diagnostics in the in vitro diagnostics industry, aiming to develop innovative products with independent intellectual property rights[121] - The company is focusing on the development of new products, including the revitalization of blood-nourishing products and the optimization of existing product structures[126] Environmental and Social Responsibility - The company aims to reduce carbon emissions per unit of GDP by 18% by 2025, compared to 2020 levels, as part of its commitment to environmental policies[98] - The company promotes clean production and energy management, conducting regular safety and environmental drills to mitigate risks[184] - The wastewater discharge in 2021 totaled 28,194 tons, with biochemical oxygen demand emissions of 101.498 kg and chemical oxygen demand emissions of 479.298 kg, all meeting national standards[181] Future Outlook and Strategic Goals - The company provided a positive outlook for the next fiscal year, projecting a revenue growth of 25% based on new product launches and market expansion strategies[149] - The company aims to achieve sales revenue of no less than 460 million yuan in 2022, with steady profit growth[123] - The company plans to enhance market penetration in regions such as Guangxi, Yunnan, and Beijing, while expanding into new markets like Sichuan, Hunan, and Anhui[126]

Financial Performance - The company's operating revenue for Q3 2021 was CNY 114,533,611.38, representing a year-on-year increase of 79.27%[5]. - The net profit attributable to shareholders for the same period was CNY 3,199,199.99, with a year-to-date net profit of CNY 7,804,270.87, reflecting a significant increase due to the acquisition of GaoSheng Bio[5][9]. - Total operating revenue for the first three quarters of 2021 reached ¥304,631,870.81, a significant increase of 68% compared to ¥181,341,788.70 in the same period of 2020[25]. - The net profit for the third quarter of 2021 was CNY 8,304,358.54, a significant recovery from a net loss of CNY 5,301,691.17 in the same period of 2020, representing a turnaround of over 200%[27]. - Operating profit for the third quarter reached CNY 12,474,974.14, compared to an operating loss of CNY 3,305,567.72 in Q3 2020, indicating a strong operational improvement[27]. - The total profit for the third quarter was CNY 12,790,001.66, a significant increase from a total loss of CNY 3,472,346.58 in Q3 2020, indicating a strong recovery in profitability[27]. Assets and Liabilities - Total assets at the end of the reporting period were CNY 1,070,138,391.85, a slight increase of 0.11% compared to the end of the previous year[6]. - Total liabilities decreased to ¥147,920,453.49 as of September 30, 2021, down from ¥217,265,963.49 at the end of 2020, a reduction of approximately 32%[24]. - The company's total assets stood at ¥1,070,138,391.85 as of September 30, 2021, slightly up from ¥1,068,937,499.81 at the end of 2020[23]. - Total current liabilities were approximately CNY 216.57 million, with accounts payable at CNY 44.19 million[36]. - Total liabilities amounted to approximately CNY 219.21 million, indicating a minor increase[36]. Shareholder Information - The total number of common shareholders at the end of the reporting period is 15,756[11]. - The largest shareholder, Zhu Rongjuan, holds 105,110,542 shares, accounting for 20.05% of total shares, with 104,960,000 shares pledged[11]. - Shareholder Yao Fangyuan reduced her holdings by 7 million shares, representing 1.34% of the total share capital[16]. - Chairman Pan Libin plans to reduce his holdings by up to 3,450,000 shares, which is 0.675% of the total share capital[17]. - As of September 30, 2021, the total number of pledged shares by major shareholders is 104,960,000 shares[19]. - The company’s major shareholder, Guangxi Guofa Investment Group, has pledged 27,325,000 shares[19]. Cash Flow and Investments - Cash flow from operating activities showed a negative net amount of CNY -46,142,961.55 year-to-date, indicating a decrease in cash inflow[5][9]. - The cash flow from operating activities showed a net outflow of CNY 46,142,961.55 in the first nine months of 2021, contrasting with a net inflow of CNY 3,346,151.16 in the same period of 2020[31]. - The company experienced a net cash outflow from investing activities of CNY 89,303,266.00 in the first nine months of 2021, compared to a net outflow of CNY 31,134,322.39 in the same period of 2020[32]. - The company raised CNY 67,799,987.40 from financing activities in the first nine months of 2021, compared to a net outflow of CNY 2,430,991.60 in the same period of 2020[32]. - The company invested RMB 10 million in Youfeng (Beijing) Biotechnology Co., Ltd., acquiring a 1% stake[15]. Operational Metrics - The company reported a significant increase in accounts receivable, up 252.78%, primarily due to receiving more commercial acceptance bills[8]. - The increase in operating costs year-to-date was 55.61%, attributed to the consolidation of GaoSheng Bio's financials[8]. - The company's basic earnings per share for Q3 2021 was CNY 0.01, unchanged from the previous year[5]. - The company’s weighted average return on equity was 0.29% for the quarter[5]. - The gross profit margin for the first three quarters of 2021 was approximately 5.3%, compared to 0.1% in the same period of 2020[25]. - Research and development expenses for the first three quarters of 2021 were ¥5,110,633.85, significantly higher than ¥22,844.21 in the same period of 2020, indicating a strategic focus on innovation[25]. Capital Structure - The company completed a private placement of 12,427,005 shares, raising a net amount of RMB 61,799,695.43, increasing registered capital to RMB 524,198,348[13]. - The company completed a non-public offering to raise funds, which contributed to its financing activities[9]. - The company has completed the registration procedures for the newly issued shares on July 28, 2021[13].

Financial Performance - The company's operating revenue for the first half of 2021 reached ¥190,098,259.43, representing a 61.85% increase compared to ¥117,452,542.53 in the same period last year[19]. - The net profit attributable to shareholders of the listed company was ¥4,605,070.88, a significant turnaround from a loss of ¥3,801,696.53 in the previous year[19]. - The net profit after deducting non-recurring gains and losses was ¥4,239,797.10, compared to a loss of ¥3,919,213.09 in the same period last year[20]. - Basic earnings per share for the reporting period is CNY 0.01, compared to CNY -0.01 in the same period last year[21]. - Diluted earnings per share for the reporting period is CNY 0.01, compared to CNY -0.01 in the same period last year[21]. - The weighted average return on equity increased by 1.13 percentage points to 0.54% from -0.59% year-on-year[21]. - The company reported a significant increase in revenue, achieving a total of 1.5 billion RMB for the first half of 2021, representing a year-on-year growth of 25%[85]. - The company provided a positive outlook for the second half of 2021, projecting a revenue growth of 20% to 30% based on current market trends[85]. Cash Flow and Assets - The net cash flow from operating activities was -¥43,656,346.65, a decline from ¥2,606,986.61 in the previous year[20]. - The total assets decreased by 7.23% to ¥991,675,736.71 from ¥1,068,937,499.81 at the end of the previous year[20]. - The company's cash and cash equivalents decreased by 57.91% to RMB 88.9 million due to the payment for the acquisition of GaoSheng Bio[53]. - The accounts receivable increased by 19.96% to RMB 261.6 million, indicating a rise in outstanding payments from customers[54]. - The cash flow from operating activities showed a net outflow of CNY 43,656,346.65, a significant decline from a net inflow of CNY 2,606,986.61 in the first half of 2020[148]. - Cash and cash equivalents at the end of the first half of 2021 were CNY 87,214,235.75, down from CNY 225,652,264.88 at the end of the first half of 2020[148]. Acquisitions and Investments - The company completed a significant asset restructuring by acquiring 100% of Gaoseng Biological, which contributed to the substantial growth in revenue and net profit[20]. - The acquisition of GaoSheng Bio was finalized at the end of 2020, and its financial results have been consolidated into the company's financial statements, leading to significant changes in revenue and costs[52]. - The company completed a private placement of 12,427,005 shares, raising a total of RMB 68.1 million, with a net amount of RMB 61.8 million after deducting issuance costs[45]. - The company has invested RMB 100 million in the BGI Win-Win Fund, which has successfully invested in 15 projects, including GaoSheng Bio[48]. Market and Industry Trends - The pharmaceutical manufacturing industry in China achieved a main business revenue of CNY 1,404.69 billion in the first half of 2021, representing a year-on-year growth of 28% and a total profit of CNY 300.04 billion, up 88% year-on-year[35]. - The national pharmaceutical circulation market sales reached CNY 2,414.9 billion in 2020, with a year-on-year growth of 2.4%, a slowdown of 6.2 percentage points compared to the previous year[36]. - The online pharmaceutical sales experienced significant growth due to the COVID-19 pandemic, with over 1,100 internet hospitals established by March 2021, enhancing online medical consultation and drug purchasing habits[38]. - The pharmaceutical industry is transitioning from high-speed growth to high-quality development, driven by national policy support and healthcare system reforms[34]. Risks and Challenges - The company is facing risks from long accounts receivable cycles in the pharmaceutical distribution industry, which may pressure cash flow and increase the risk of bad debts[63]. - High reliance on upstream suppliers in the DNA testing industry poses a risk due to the high concentration of suppliers and the advanced technology requirements[65]. - The pharmaceutical distribution companies are facing increasing operational pressure due to intensified market competition and policies such as "zero markup" and centralized procurement[42]. Environmental Compliance - The company has not faced any administrative penalties due to environmental issues during the reporting period[79]. - The wastewater treatment system upgrade at Guofa Pharmaceutical Plant is expected to be completed and operational by September 2021[79]. - The company has adhered to environmental protection laws and has not been classified as a key pollutant discharge unit[80]. Shareholder and Governance - The actual controller and shareholders have committed to not transferring newly issued shares for 12 months post-issuance[82]. - The company has committed to maintaining independence and ensuring no adverse effects on its operations from controlling shareholders[87]. - There were no significant lawsuits or arbitration matters during the reporting period[89]. - The company has not disclosed any new product developments or market expansion strategies in the provided content[120].