证券代码：002821 证券简称：凯莱英 公告编号：2025-060 凯莱英医药集团（天津）股份有限公司（以下简称"公司"）第五届董事会 第三次会议通知于 2025 年 9 月 9 日以电子邮件和书面形式发送给各位董事及高 级管理人员，会议于 2025 年 9 月 15 日以通讯方式召开。公司应到董事 9 名，实 到董事 9 名，公司部分高级管理人员列席了本次会议。会议由公司董事长 HAO HONG 先生召集并主持，会议的召集和召开符合《公司法》及相关法律、法规以 及《公司章程》的有关规定。 二、董事会议案审议情况 会议采用通讯方式进行表决，经全体与会董事审议并表决，通过了如下决议： 1、审议通过了《关于使用部分暂时闲置募集资金进行现金管理的议案》 凯莱英医药集团（天津）股份有限公司 第五届董事会第三次会议决议的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 具体内容详见同日刊登于《中国证券报》、《证券时报》和巨潮资讯网 （http://www.cninfo.com.cn/）的公告信息。 三、备查文件 1、公司第五届董事会第三次会 ...

第一创业证券承销保荐有限责任公司 关于凯莱英医药集团（天津）股份有限公司 使用暂时闲置募集资金进行现金管理的核查意见 第一创业证券承销保荐有限责任公司（以下简称"一创投行"或"保荐机构"） 作为凯莱英医药集团（天津）股份有限公司（以下简称"凯莱英"或"公司"）的保 荐机构，根据《证券发行上市保荐业务管理办法》、《深圳证券交易所股票上市规 则》、《深圳证券交易所上市公司自律监管指引第 1 号——主板上市公司规范运 作》、《上市公司募集资金监管规则》等法律和规范性文件的要求，对凯莱英医 药集团（天津）股份有限公司使用暂时闲置募集资金进行现金管理情况进行了审 慎核查。具体情况如下： 一、募集资金基本情况 经中国证券监督管理委员会证监许可[2020]1912 号文《关于核准凯莱英医药 集团（天津）股份有限公司非公开发行股票的批复》核准，公司于 2020 年 9 月 向特定投资者发行人民币普通股（A 股）股票 10,178,731.00 股，每股发行价为 227.00 元/股，募集资金总额为人民币 2,310,571,937.00 元，扣除承销费用（不含 税）32,696,772.70 元，公司实际收到募集资金人民币 ...

Core Insights - Kailaiying's stock increased by 5.27% on September 15, reaching a price of 117.99 CNY per share, with a trading volume of 1.247 billion CNY and a turnover rate of 3.43%, resulting in a total market capitalization of 42.546 billion CNY [1] Company Overview - Kailaiying Pharmaceutical Group (Tianjin) Co., Ltd. is located in Tianjin Economic and Technological Development Zone, established on October 7, 1998, and listed on November 18, 2016 [1] - The company's main business involves providing CMO (Contract Manufacturing Organization) pharmaceutical outsourcing services, with revenue composition as follows: 76.19% from small molecule CDMO solutions, 23.71% from emerging services, and 0.10% from other sources [1] Fund Holdings - According to data from the top ten holdings of funds, one fund under Jiashi Fund has a significant position in Kailaiying. Jiashi Healthcare Stock Fund (000711) held 387,100 shares in the second quarter, accounting for 4.14% of the fund's net value, ranking as the eighth largest holding [2] - The Jiashi Healthcare Stock Fund was established on August 13, 2014, with a latest scale of 825 million CNY. Year-to-date returns are 41.32%, ranking 748 out of 4222 in its category; the one-year return is 53.88%, ranking 1833 out of 3802; and since inception, the return is 131.9% [2] - The fund manager, Hao Miao, has been in position for 6 years and 244 days, with total assets under management of 3.652 billion CNY. The best fund return during his tenure is 183.83%, while the worst is -28.36% [2]

Group 1 - The core point of the news is that Kailaiying's stock price increased by 5.27% to 117.99 CNY per share, with a trading volume of 1.245 billion CNY and a turnover rate of 3.43%, resulting in a total market capitalization of 42.546 billion CNY [1] - Kailaiying Pharmaceutical Group (Tianjin) Co., Ltd. is located in Tianjin Economic and Technological Development Zone and was established on October 7, 1998, with its listing date on November 18, 2016 [1] - The company's main business involves providing CMO (Contract Manufacturing Organization) pharmaceutical outsourcing services, with revenue composition being 76.19% from small molecule CDMO solutions, 23.71% from emerging services, and 0.10% from other sources [1] Group 2 - From the perspective of major fund holdings, one fund under China Ocean Fund has a significant position in Kailaiying, specifically the China Ocean Medical Mixed A Fund (000878), which increased its holdings by 73,900 shares in the second quarter, bringing the total to 224,300 shares, accounting for 6.25% of the fund's net value [2] - The China Ocean Medical Mixed A Fund (000878) was established on December 17, 2014, with a latest scale of 230 million CNY, achieving a year-to-date return of 29.89% and a one-year return of 41.89% [2] - The fund manager, Yao Wei, has been in position for 6 years and 281 days, with the fund's total asset scale at 456 million CNY, achieving the best return of 65.93% and the worst return of -38.1% during his tenure [2]

Group 1 - The core point of the news is that Kailaiying's stock price dropped by 5.86% to 104.50 CNY per share, with a trading volume of 282 million CNY and a turnover rate of 0.86%, resulting in a total market capitalization of 37.682 billion CNY [1] - Kailaiying Pharmaceutical Group (Tianjin) Co., Ltd. is located in Tianjin Economic and Technological Development Zone and was established on October 7, 1998, with its listing date on November 18, 2016 [1] - The company's main business involves providing CMO pharmaceutical outsourcing services, with revenue composition being 76.19% from small molecule CDMO solutions, 23.71% from emerging services, and 0.10% from other sources [1] Group 2 - From the perspective of Kailaiying's top ten circulating shareholders, Huabao Fund's ETF reduced its holdings by 1.0921 million shares in the second quarter, now holding 6.6467 million shares, which accounts for 1.93% of circulating shares [2] - The estimated floating loss for Huabao Zhongzheng Medical ETF today is approximately 43.2035 million CNY [2] - Huabao Zhongzheng Medical ETF was established on May 20, 2019, with a latest scale of 26.147 billion CNY, and has achieved a year-to-date return of 19.93% [2]

Core Viewpoint - The company is actively expanding its capabilities in the peptide CDMO sector, particularly in the weight loss area, and is well-positioned for future growth despite potential regulatory challenges in the U.S. market [1][2] Group 1: Peptide Capacity and Market Demand - The company's peptide CDMO business is primarily driven by the rapidly growing weight loss sector, with participation in over ten molecular collaborations [1] - Projects in the weight loss field are expected to enter the PPQ (Process Performance Qualification) stage next year, indicating a positive trajectory for capacity utilization [1] - The company’s capacity expansion plans are based not only on current utilization rates but also on anticipated future commercialization needs from clients [1] Group 2: Order Backlog and Revenue Growth - As of the disclosure date of the 2025 semi-annual report, the company has a total order backlog of nearly $1.1 billion, providing a solid foundation for annual performance growth [1] - The European market has shown exceptional performance, with revenue reaching 548 million yuan in the first half of the year, representing a year-on-year growth of over 200% [1] Group 3: Global Market Strategy and Regulatory Concerns - The company is focused on accelerating global market expansion and emerging business layouts to strengthen its competitive advantage in the chemical small molecule and peptide CDMO sectors [2] - Concerns regarding potential strict regulations on Chinese pharmaceuticals by the U.S. are deemed to have limited impact on the company's global business expansion [1] - The company aims to continuously enhance its overall competitiveness while closely monitoring external policy impacts [1]

Investment Rating - The investment rating for the company is "Outperform the Market" (首次覆盖) [1] Core Insights - The company, Kailaiying, is a leading, technology-driven one-stop CDMO service provider, established in 1998, and is the second-largest chemical drug CDMO enterprise in China, serving over 1,100 global clients including Pfizer and Merck [3][4] - The small molecule CDMO business serves as the foundation of the company, leveraging core technologies such as continuous flow chemistry and enzyme catalysis to maintain a competitive edge in oncology and antiviral services [4] - The company is diversifying its business into six emerging areas, including large molecule CDMO, formulation CDMO, clinical CRO, and synthetic biology, capitalizing on its established brand and technological advantages [5] - The company is expanding its global footprint with a collaborative network across the US, Europe, and China, enhancing its supply chain resilience and operational efficiency [6] Summary by Sections 1. Business Structure - The small molecule CDMO business remains the cornerstone, accounting for approximately 90% of revenue from 2018 to 2022, while emerging businesses are expected to grow to 15% and 21% of revenue in 2023 and 2024, respectively [13][14] 2. Financial Forecast and Valuation - Revenue projections for 2025-2027 are estimated at 6.68 billion, 7.53 billion, and 8.29 billion yuan, with year-on-year growth rates of 15%, 13%, and 10% respectively. The gross margin is expected to stabilize at 43% [7] - The current stock price corresponds to a PE ratio of 34, 30, and 26 for the years 2025, 2026, and 2027, respectively, indicating a price range of 113.07 to 129.84 yuan, suggesting a premium of 4-20% over the current price [7] 3. Market Dynamics - The global CDMO market is projected to grow from approximately $75 billion in 2023 to $133 billion by 2027, with the small molecule CDMO market expected to reach $106.7 billion by 2028, driven by increased R&D investments from large pharmaceutical companies [28][30] 4. Competitive Landscape - The company is positioned in a competitive landscape dominated by North America and Europe, which account for 70% of the global small molecule CDMO market, while emerging markets like China and India are rapidly growing [35] 5. Technological and Operational Advantages - The company has established a leading position in continuous reaction technology and enzyme engineering, supported by a robust quality management system that meets global standards [55][56] - The company’s profitability metrics, including a gross margin of 42.36% and a net profit margin of 16.35%, indicate strong operational efficiency compared to peers [56]

| 股份代號: | 06821 | | --- | --- | | 上市法國名稱: | 訓萊英醫藥集團(天津)股份有限公司 - H | | 日期 (日 / 月 / 年): | 11/08/2025 - 11/09/2025 | 格隆汇9月11日丨根据联交所最新权益披露资料显示，2025年9月5日，凯莱英(06821.HK)获JPMorgan Chase & Co.以每股均价92.6442港元增持好仓8.4万股， 涉资约778.21万港元。 增持后，JPMorgan Chase & Co.最新持好仓数目为1,669,746股，持好仓比例由5.75%上升至6.06%。 | 家福家 | 大船車/華車/最高行政人員名 作出披露的 貫入/ 朝出或法及的 每船的平均價 | | | | | | 持有權益的股份數目 佔已發行的 有關事件的日期 * | | --- | --- | --- | --- | --- | --- | --- | --- | | | | | 四十三十二 | | | 語學生 | 有技景裡版(日/月/年) | | | | | | | | | 位自分网 | | | | | | | | | 90 | | CS ...

Group 1 - The core point of the article is that Schroders PLC has increased its stake in Kailaiying (06821.HK) by purchasing 115,300 shares at an average price of HKD 97.5696 per share, amounting to approximately HKD 11.25 million [1] - Following this transaction, Schroders PLC's total shareholding in Kailaiying has risen to 5.3142 million shares, increasing its ownership percentage from 18.87% to 19.29% [1]

Group 1 - Schroders PLC increased its stake in Kelaiying (002821) by 115,300 shares at an average price of 97.5696 HKD per share, totaling approximately 11.2498 million HKD [1] - After the increase, Schroders PLC's total shareholding in Kelaiying reached 5.3142 million shares, representing a holding percentage of 19.29% [1]