Core Viewpoint - Eli Lilly and Company has announced a definitive agreement to acquire Ventyx Biosciences for $14.00 per share, totaling approximately $1.2 billion, to enhance its capabilities in treating inflammatory-mediated diseases [1][3][4]. Company Overview - Eli Lilly is a biopharmaceutical company focused on innovative therapies for various health challenges, including diabetes, obesity, Alzheimer's disease, and immune system disorders [8]. - Ventyx Biosciences is a clinical-stage biopharmaceutical company developing oral therapies targeting inflammation-mediated diseases, with a focus on small molecule therapeutics [9]. Acquisition Details - The acquisition price represents a 62% premium over Ventyx's 30-day volume-weighted average trading price as of January 5, 2026 [4]. - The transaction is expected to close in the first half of 2026, pending approval from Ventyx stockholders and regulatory approvals [3][4]. - Entities affiliated with New Science Ventures and Ventyx's directors and officers have signed agreements to support the transaction, representing about 10% of Ventyx's outstanding common stock [5]. Clinical Pipeline - Ventyx's pipeline includes NLRP3 inhibitors aimed at treating chronic inflammation across various disease states, including cardiometabolic disorders and neurodegenerative diseases [2][3]. - The company's lead candidates include VTX2735, a Phase 2 NLRP3 inhibitor for recurrent pericarditis, and VTX3232, which has shown promise in reducing cardiovascular risk factors and is also being studied in early-stage Parkinson's disease [9]. Strategic Importance - The acquisition is seen as a strategic move for Lilly to strengthen its portfolio in addressing chronic inflammation, which is increasingly recognized as a key driver of many chronic diseases [3][4]. - Lilly's commitment to advancing innovative oral drugs aligns with Ventyx's focus on unmet medical needs in inflammatory diseases [3].

Market Overview - U.S. stocks showed mixed performance, with the Dow Jones index declining approximately 0.2% on Wednesday [1] Company Highlights - Monte Rosa Therapeutics Inc (NASDAQ:GLUE) experienced a significant increase in share price, rising 45.2% to $23.25 after announcing interim data from a Phase 1 clinical study for MRT-8102 [1] - Ventyx Biosciences Inc (NASDAQ:VTYX) shares surged 37.5% to $13.82 following reports of advanced acquisition talks with Eli Lilly & Co. (NYSE:LLY) for over $1 billion [2] - Neumora Therapeutics Inc (NASDAQ:NMRA) saw a rise of 24.7% to $2.27 [2] - Regencell Bioscience Holdings Ltd (NASDAQ:RGC) increased by 21.1% to $40.00 [2] - Erasca Inc (NASDAQ:ERAS) rose 17.1% to $4.25, with Piper Sandler initiating coverage with an Overweight rating and a price target of $5 [2] - Anywhere Real Estate Inc (NYSE:HOUS) gained 15.6% to $16.71 [2] - AXT Inc (NASDAQ:AXTI) increased by 13.8% to $22.96 [2] - Immuneering Corp (NASDAQ:IMRX) rose 13.1% to $7.60 [2] - Compass Therapeutics Inc. (NASDAQ:CMPX) gained 13.1% to $5.56 [2] - MBX Biosciences Inc (NASDAQ:MBX) rose 11.2% to $31.90 [2] - Rezolve AI PLC (NASDAQ:RZLV) increased by 10.8% to $3.36 [2] - United Microelectronics Corp (NYSE:UMC) gained 10.4% to $8.96 after reporting sales growth for December and the full year [2] - PBF Energy Inc (NYSE:PBF) rose 9.2% to $29.73 [2] - Navan Inc (NASDAQ:NAVN) increased by 8.3% to $18.42 [2] - Ascentage Pharma Group International (NASDAQ:AAPG) gained 8.3% to $28.17 after announcing IND clearance for BTK Degrader APG-3288 by the U.S. FDA [2] - Intel Corp (NASDAQ:INTC) rose 6.4% to $42.60 as the company is enhancing its gaming strategy by developing a new chip for handheld gaming devices [2]

此外，Ventyx的一款实验性药物目前正处于中期临床阶段，用于治疗一种与肥胖相关的心血管疾病，被 视为其管线中的重要潜力项目。 周三，Ventyx Biosciences(VTYX.US)股价暴涨，截至发稿，该股涨超37%，报13.79美元。据悉礼来 (LLY.US)接近达成以超10亿美元收购该公司的交易。若该交易达成，将为礼来在研管线新增炎症性肠病 相关药物，包括克罗恩病和溃疡性结肠炎治疗项目，同时还将补充帕金森病等疾病领域的研发资产。 ...

智通财经APP获悉，周三，Ventyx Biosciences(VTYX.US)股价暴涨，截至发稿，该股涨超37%，报13.79 美元。据悉礼来(LLY.US)接近达成以超10亿美元收购该公司的交易。若该交易达成，将为礼来在研管线 新增炎症性肠病相关药物，包括克罗恩病和溃疡性结肠炎治疗项目，同时还将补充帕金森病等疾病领域 的研发资产。 此外，Ventyx的一款实验性药物目前正处于中期临床阶段，用于治疗一种与肥胖相关的心血管疾病，被 视为其管线中的重要潜力项目。 ...

Market Overview - As of January 7, U.S. stock index futures showed mixed results, with Dow futures up by 0.04%, S&P 500 futures down by 0.08%, and Nasdaq futures down by 0.24% [1] - European indices also displayed varied performance, with Germany's DAX up by 0.55%, the UK's FTSE 100 down by 0.65%, and France's CAC40 down by 0.15% [2][3] - WTI crude oil prices fell by 0.37% to $56.92 per barrel, while Brent crude oil decreased by 0.10% to $60.64 per barrel [3][4] Economic Data and Predictions - The U.S. is set to release key employment data, including the December ADP employment report, which is expected to show an increase of 47,000 jobs, rebounding from a previous negative forecast of 32,000 jobs [5] - The JOLTs report is anticipated to show a slight decline in job openings to 7.6 million for November [5] - In the options market, traders are increasingly betting that the 10-year U.S. Treasury yield will drop below 4% in the coming weeks, reflecting a bullish sentiment [6] Company News - Warner Bros. rejected a revised acquisition proposal from Paramount, reaffirming its support for a merger with Netflix, which it believes is a superior option [9] - United Microelectronics Corporation (UMC) reported a 2.26% year-over-year revenue growth for 2025, reaching NT$237.55 billion, marking the second-highest revenue in its history [9] - Meta announced a significant demand for its AI smart glasses in the U.S., leading to a delay in its global expansion plans due to inventory constraints [10] - NVIDIA's CFO indicated that the company's revenue will likely exceed the previously projected $500 billion by the end of 2026, driven by strong demand in the data center business [11] - Ventyx Biosciences shares surged by 56.22% following reports of a potential $1 billion acquisition by Eli Lilly, aimed at expanding its immunology portfolio [12] - Chevron is reportedly collaborating with Quantum Energy Partners to acquire international assets from Lukoil, valued at $22 billion [13]

Core Viewpoint - Premarket trading is showing significant activity with notable price movements indicating potential investment opportunities before the market opens [1] Premarket Gainers - Ventyx Biosciences, Inc. (VTYX) increased by 57% to $15.79 [3] - Cardio Diagnostics Holdings, Inc. (CDIO) rose by 36% to $4.02 [3] - Monte Rosa Therapeutics, Inc. (GLUE) saw a 28% increase to $20.54 [3] - Momentus Inc. (MNTS) gained 27% reaching $12.50 [3] - BioAge Labs, Inc. (BIOA) went up by 13% to $17.50 [3] - Neumora Therapeutics, Inc. (NMRA) increased by 11% to $2.03 [3] - Mobileye Global Inc. (MBLY) rose by 10% to $13.45 [3] - Society Pass Incorporated (SOPA) increased by 10% to $3.47 [3] - SU Group Holdings Limited (SUGP) saw an 8% rise to $6.32 [3] - Critical Metals Corp. (CRML) gained 7% reaching $12.73 [3] Premarket Losers - Evolution Metals & Technologies Corp. (EMAT) decreased by 28% to $15.20 [4] - Ascent Solar Technologies, Inc. (ASTI) fell by 12% to $4.65 [4] - Apogee Enterprises, Inc. (APOG) saw a 10% decline to $33.30 [4] - Next Technology Holding Inc. (NXTT) dropped by 8% to $8.49 [4] - AST SpaceMobile, Inc. (ASTS) decreased by 7% to $90.45 [4] - Nomadar Corp. (NOMA) fell by 7% to $3.66 [4] - EZGO Technologies Ltd. (EZGO) decreased by 7% to $1.99 [4] - Cohen & Company Inc. (COHN) saw a 6% decline to $28.30 [4] - PMGC Holdings Inc. (ELAB) dropped by 4% to $5.34 [4] - Anghami Inc. (ANGH) decreased by 3% to $4.49 [4]

美国生物制药公司Ventyx Biosciences(VTYX.US)盘前飙升70%，报17.11美元。据华尔街日报引述消息 称，礼来就拟以超过10亿美元收购Ventyx Biosciences的交易进行深入谈判。潜在收购Ventyx将为礼来的 产品管线增加治疗炎症性肠病的药物，以及治疗帕金森等疾病的药物。此外，Ventyx的一种实验性药物 目前正在中期开发阶段，用于治疗与肥胖相关的心血管疾病。(格隆汇) ...

Ventyx Biosciences Inc. (NASDAQ:VTYX) shares are trending on Wednesday. Check out the current price of VTVX stock here. Shares of the biopharma company jumped 62.59% to $16.34 in after-hours trading on Tuesday, following reports that Indianapolis-based Eli Lilly & Co. (NYSE:LLY) is in advanced talks to acquire the company for more than $1 billion, according to The Wall Street Journal.The report, citing sources, said a deal could be announced imminently.Ventyx and Eli Lilly did not immediately respond to Ben ...

智通财经APP获悉，据报道，礼来(LLY.US)正就以超过10亿美元的价格收购Ventyx Biosciences(VTYX.US)进行深入谈判，以拓展其在免疫学领域的业务。截至发稿，Ventyx股价在美股夜 盘交易中上涨62.59%，至16.34美元。这家总部位于圣地亚哥的生物技术公司专注于研发治疗克罗恩病 和类风湿性关节炎等炎症性疾病的药物，按此价格计算，其市值将增加4.339亿美元。Ventyx收购案的 报道正值制药行业准备参加在旧金山举行的摩根大通医疗保健大会之际，该大会历来是并购交易的热门 场所。 礼来公司表示，免疫学是其关键增长领域，该公司希望在糖尿病和肥胖症治疗领域取得巨大成功的基础 上，进一步拓展业务。这些成功吸引了投资者和患者的关注。该公司目前已销售多种治疗关节炎和银屑 病等炎症性疾病的药物，包括Taltz，但Taltz的关键专利保护将在未来几年内到期。 与此同时，该公司正在寻求收购以扩充其产品线。2024年，该公司以32亿美元收购了Morphic Therapeutics，获得了一种用于治疗炎症性肠病的实验性药物。此外，该公司还斥资24亿美元收购了 Dice Therapeutics，后者 ...

与此同时，该公司正在寻求收购以扩充其产品线。2024年，该公司以32亿美元收购了Morphic Therapeutics，获得了一种用于治疗炎症性肠病的实验性药物。此外，该公司还斥资24亿美元收购了 Dice Therapeutics，后者是一家开发口服银屑病疗法的公司。 礼来公司表示，免疫学是其关键增长领域，该公司希望在糖尿病和肥胖症治疗领域取得巨大成功的基础 上，进一步拓展业务。这些成功吸引了投资者和患者的关注。该公司目前已销售多种治疗关节炎和银屑 病等炎症性疾病的药物，包括Taltz，但Taltz的关键专利保护将在未来几年内到期。 据报道，礼来(LLY.US)正就以超过10亿美元的价格收购Ventyx Biosciences(VTYX.US)进行深入谈判，以 拓展其在免疫学领域的业务。截至发稿，Ventyx股价在美股夜盘交易中上涨62.59%，至16.34美元。这 家总部位于圣地亚哥的生物技术公司专注于研发治疗克罗恩病和类风湿性关节炎等炎症性疾病的药物， 按此价格计算，其市值将增加4.339亿美元。Ventyx收购案的报道正值制药行业准备参加在旧金山举行 的摩根大通医疗保健大会之际，该大会历来是并购交易 ...