Core Viewpoint - The company, Innocare Pharma, will hold an investor briefing on November 14, 2025, to discuss its Q3 2025 financial results and address investor inquiries [2][3][4]. Group 1: Meeting Details - The investor briefing is scheduled for November 14, 2025, from 11:00 AM to 12:00 PM [4]. - The meeting will take place at the Shanghai Stock Exchange Roadshow Center, accessible online [4]. - Investors can participate in the meeting through the internet and submit questions in advance via the Roadshow Center or the company's email [5][6]. Group 2: Participants - Key participants in the meeting will include Dr. Jisong Cui (Chairman and CEO), Ms. Hu Lan (Independent Non-Executive Director), and Mr. Fu Xin (CFO) [4]. - The company may adjust the list of attendees based on special circumstances [4]. Group 3: Investor Interaction - Investors can submit questions from November 7 to November 13, 2025, before 4:00 PM [5]. - The company will respond to commonly asked questions during the briefing [3][5]. Group 4: Contact Information - For inquiries, investors can contact the domestic securities affairs department via phone or email [6]. - The details of the meeting and its main content will be available on the Roadshow Center after the event [6].

Core Insights - The company, Innovent Biologics, announced that its newly developed BCL2 inhibitor Mesutoclax and BTK inhibitor Orelabrutinib have over 20 research results selected for the 67th American Society of Hematology (ASH) Annual Meeting, including 2 oral presentations and 20 poster displays [1][2][4]. Group 1: Mesutoclax Research Highlights - Mesutoclax has three studies selected for the ASH meeting, with one oral presentation focused on its efficacy in treating relapsed/refractory mantle cell lymphoma (MCL) showing high remission rates even in patients previously resistant to BTK inhibitors [1]. - The oral presentation titled "Efficacy and tolerability of mesutoclax monotherapy in Relapsed/Refractory Mantle Cell Lymphoma patients" is scheduled for December 8, 2025 [1]. - Two poster presentations include studies on Mesutoclax's activity in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and myeloid malignancies, demonstrating encouraging efficacy and safety [2][3]. Group 2: Orelabrutinib Research Highlights - Orelabrutinib has over 20 studies selected for the ASH meeting, including one oral presentation and multiple poster displays covering various diseases such as marginal zone lymphoma (MZL) and diffuse large B-cell lymphoma (DLBCL) [4][5]. - The oral presentation titled "Mid-treatment CSF ctdna and MYD88 clearance outperform PET-CT in predicting response and survival to orelabrutinib-based induction in newly diagnosed PCNSL" is scheduled for December 6, 2025 [4]. - Key poster presentations include studies on Orelabrutinib combined with other therapies for treating marginal zone lymphoma and DLBCL, indicating promising results [5][6][7]. Group 3: Company Overview - Innovent Biologics is a commercial-stage biopharmaceutical company focused on developing innovative drugs for oncology and autoimmune diseases, with multiple products in commercialization, clinical, and preclinical stages [10]. - The company has branches in major cities including Beijing, Nanjing, Shanghai, Guangzhou, Hong Kong, and the United States [10].

Core Points - The company, Innovent Biologics (09969.HK), announced that it will release its Q3 2025 report on November 14, 2025 [1] - To provide investors with a comprehensive understanding of its Q3 2025 operational results and financial status, the company plans to hold a performance briefing on the same day from 11:00 AM to 12:00 PM [1] - The briefing will address questions of interest to investors [1]

Core Insights - The pharmaceutical and biotechnology sectors are experiencing a downturn, with the pharmaceutical index dropping 2.81% from October 27 to October 31, underperforming the Shanghai Composite Index by 2 percentage points, marking six consecutive weeks of underperformance [4] - Jiangsu Dingtai Pharmaceutical Research Group has submitted its IPO application to the Hong Kong Stock Exchange, shifting its strategy from A-share listing to Hong Kong due to unfavorable IPO conditions [5] - The approval of the first EGFR ADC (antibody-drug conjugate) in China by Lepu Biotech for treating recurrent/metastatic nasopharyngeal carcinoma marks a significant milestone in the domestic ADC market [10][11] Industry Trends - The pharmaceutical index has shown a consistent decline, indicating a challenging environment for the sector [4] - The clinical trial landscape is active, with 64 new clinical trial registrations reported by the National Medical Products Administration, including 16 innovative drug trials in advanced stages [7] - The approval of Sibeprenlimab by Otsuka Pharmaceutical for IgA nephropathy highlights the growing focus on targeted therapies in chronic kidney diseases [12][13] Company Developments - Dingtai Pharmaceutical's revenue is projected to exceed 700 million yuan from 2022 to 2024, with a turnaround to profitability expected in the first half of 2025 [5] - Lepu Biotech's newly approved drug, Weibeiketuotai monoclonal antibody, shows promising clinical results, with an objective response rate of 30.2% in previously treated nasopharyngeal cancer patients [11] - Otsuka's Sibeprenlimab is positioned to potentially become a first-line treatment option for IgA nephropathy, addressing significant unmet clinical needs [12][13]

Core Viewpoint - The company, Innovent Biologics (09969.HK), announced that it will release its Q3 2025 financial report on November 14, 2025, and will hold a performance briefing to discuss the results and address investor concerns [1] Group 1 - The company plans to hold a performance briefing on November 14, 2025, from 11:00 AM to 12:00 PM [1] - The briefing aims to provide investors with a comprehensive understanding of the company's Q3 2025 operational results and financial status [1] - The event will facilitate communication regarding issues of interest to investors [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因倚賴該等內容而引致的任何損失承擔任何責任。 InnoCare Pharma Limited 諾誠健華醫藥有限公司 （ 於 開 曼 群 島 註 冊 成 立 的 有 限 公 司 ） （股份代號：9969） 诺诚健华医药有限公司 海外監管公告 本公告乃諾誠健華醫藥有限公司（「本公司」）根據香港聯合交易所有限公司證 券上市規則第13.10B條作出。 茲載列本公司於上海證券交易所網站刊登之《關於召開2025年第三季度業績說 明會的公告》。 承董事會命 諾誠健華醫藥有限公司 主席兼執行董事 崔霽松博士 香港，二零二五年十一月五日 於本公告日期，董事會包括主席兼執行董事崔霽松博士；執行董事趙仁濱博士；非執行董事 施一公博士及謝榕剛先生；以及獨立非執行董事胡蘭女士、董丹丹博士及管坤良教授。 | A | 股代码：688428 | 股简称：诺诚健华 A | 公告编号：2025-037 | | --- | --- | --- | --- | | 港股代码：09969 ...

致：香港交易及結算所有限公司 公司名稱: 諾誠健華醫藥有限公司（於開曼群島註冊成立的有限公司） 呈交日期: 2025年11月5日 FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年10月31日 狀態: 新提交 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 09969 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 25,000,000,000 | USD | | 0.000002 | USD | | 50,000 | | 增加 / 減少 (-) | | | | | | | USD | | | | 本月底結存 | | | 25,000,000,000 | USD | | 0.000002 | U ...

Core Insights - The Science and Technology Innovation Board (STAR Market) has successfully gathered 592 listed companies by October 2025, with a cumulative IPO fundraising scale of 934.6 billion yuan and total financing exceeding 1.1 trillion yuan, becoming a key force in nurturing new productive forces and upgrading the modern industrial system [1][2] - Over the past five years, STAR Market companies have shown strong growth, with a compound annual growth rate of 18% in operating income and 9% in net profit attributable to shareholders, indicating robust growth potential [2][3] - The STAR Market has established a virtuous cycle ecosystem of "technology - industry - capital," effectively promoting the efficient allocation of innovative resources and attracting talent and investment [6][8] Group 1: Financial Performance - By October 2025, the STAR Market has raised a total of 934.6 billion yuan through IPOs, with total financing surpassing 1.1 trillion yuan [1] - The compound annual growth rates for operating income and net profit attributable to shareholders for STAR Market companies are 18% and 9%, respectively, since 2019 [2] - In the integrated circuit sector, 119 disclosed companies reported a revenue growth of 27% and a net profit growth of 83% year-on-year for the first three quarters of 2025 [3] Group 2: Industry Focus and Innovation - The STAR Market has maintained a focus on "hard technology," with over 80% of listed companies in emerging industries such as new-generation information technology, biomedicine, and high-end equipment manufacturing [3] - The STAR Market has seen significant advancements in key technologies, with companies like He Yuan Bio and Guo Dun Quantum achieving breakthroughs in innovative drugs and semiconductor technologies [4] - As of 2025, STAR Market companies have formed over 130,000 invention patents, with an average of 230 patents per company, showcasing a strong emphasis on innovation [4][5] Group 3: Ecosystem and Market Dynamics - The STAR Market has successfully attracted over 60% of its founding teams from scientific and engineering backgrounds, fostering a culture of innovation [6] - Approximately 90% of STAR Market companies received venture capital investment before going public, indicating strong investor confidence [6] - The STAR Market has developed a comprehensive index system with 33 indices, and the total scale of STAR Market-related index tracking products exceeds 330 billion yuan [6][7] Group 4: Regulatory and Institutional Innovations - The STAR Market has pioneered various institutional innovations, including multi-dimensional listing standards and a small-scale rapid financing mechanism, providing valuable lessons for other market segments [8] - Recent reforms, such as the "1+6" initiative, have further enhanced the inclusivity of the STAR Market, allowing for the expansion of standards to cover cutting-edge fields like artificial intelligence [8] - The Shanghai Stock Exchange aims to leverage the STAR Market's role as a "testing ground" to better identify high-quality technology enterprises and support their listing [9]

FF301 股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2025年10月31日 狀態: 新提交 致：香港交易及結算所有限公司 呈交日期: 2025年11月5日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | 不適用 | | 於香港聯交所上市 (註1) | | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 09969 | 說明 | | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | | 法定/註冊股本 | | | 上月底結存 | | | 25,000,000,000 | USD | | 0.000002 | USD | | 50,000 | | 增加 / 減少 (-) | | | | | | | USD | | | | 本月底結存 | | | 25,000,000,000 | USD | | 0.000002 | USD | | 50,000 | 本月底法定/註冊股本總額： USD ...

Core Insights - A total of 77 stocks in the Shanghai and Shenzhen markets have experienced net inflows of main funds for five consecutive days or more as of November 5, with Cambricon Technologies (寒武纪-U) leading with 50 days of continuous inflow [1] - The total net inflow of main funds for Cambricon Technologies reached 6.325 billion yuan, followed by Shanghai Pudong Development Bank with a net inflow of 777 million yuan over five days [1] - In terms of the proportion of net inflow to trading volume, *ST Baoying ranks first, with a 47.72% increase over the past eight days [1] Summary by Category Stocks with Continuous Net Inflows - Cambricon Technologies (688256) has seen net inflows for 50 days totaling 6.325 billion yuan, with a price increase of 44.33% [1] - Shanghai Pudong Development Bank (600000) recorded net inflows of 777 million yuan over five days, with a price increase of 0.42% [1] - CITIC Bank (601998) had net inflows of 439 million yuan over six days, with a price increase of 3.85% [1] Notable Performers - *ST Baoying had the highest net inflow ratio, with a significant price increase of 47.72% over the last eight days [1] - Other notable stocks include Jiangsu Bank (600919) with a net inflow of 342 million yuan and a price increase of 5.70%, and Yaxing Anchor Chain (601890) with a net inflow of 331 million yuan and a price increase of 10.16% [1] Additional Stocks with Inflows - Other stocks with notable net inflows include: - China Shenhua (601088) with 314 million yuan and a 3.42% increase [1] - Haotian Co., Ltd. (603759) with 166 million yuan and a 64.35% increase over 11 days [1] - Microelectronic Physiology (688351) with 140 million yuan and a 12.94% increase [1]