研究报告 Research Report 9 Feb 2026 香港医疗 Hong Kong Health Care 医药行业周报（2026.02.02-2026.02.06）：市场情绪回暖；看好基本面表现强劲的创新药产业链龙头 Healthcare Weekly (2026.02.02-2026.02.06): Market Sentiment Warms; Bullish on Leaders in Innovative Drug Chain with Strong Fundamentals [Table_yemei1] 观点聚焦 Investment Focus | [Table_Info] | | | | | --- | --- | --- | --- | | 股票名称 | 评级 | 股票名称 | 评级 | | 百济神州 | Outperform 华润医药 | | Outperform | | 京东健康 | Outperform 国药控股 | | Neutral | | 药明生物 | Outperform 映恩生物 | | Outperform | | 信达生物 | Outperform 金斯瑞生物科 ...

Core Insights - Neuroscience has historically been viewed as a high-risk area in pharmaceutical R&D, particularly for conditions like Alzheimer's disease and schizophrenia, due to complex pathophysiological mechanisms leading to high failure rates [1] - Recently, there has been a notable shift as the neuroscience sector is gaining momentum, driven by commercial success in Alzheimer's treatments and advancements in technologies such as small molecules, RNAi, cell therapy, and AI [1][6] - The combination of technological breakthroughs and market confidence is prompting multinational corporations (MNCs) to engage in mergers, acquisitions, and collaborations, signaling a potential "gold rush" in neuroscience [1] Industry Trends - The number of clinical trials and transactions in the neuroscience field is increasing, with 138 new drugs currently undergoing 182 clinical trials for Alzheimer's disease, marking a 9% increase from 2024 [2] - Over the past five years, more than 200 new clinical trials have been initiated for Alzheimer's disease, depression, and Parkinson's disease, indicating a growing interest in these areas [5] Market Developments - Confidence in the sector is rising, particularly due to breakthroughs in Alzheimer's treatments, such as Biogen's Leqembi, which achieved sales of $214 million in 2024 and $121 million in Q3 2025, reflecting an 82% year-over-year increase [6] - The approval of diagnostic methods, such as the Elecsys® pTau181 blood test by Roche and Eli Lilly, is enhancing the efficiency of Alzheimer's diagnosis and treatment [7] Technological Innovations - Emerging technologies like brain-computer interfaces and brain stimulation devices are becoming part of the investment narrative in neuroscience, with companies like Neuralink and Synchron conducting human clinical trials [8] - Advances in biomarkers and imaging agents are improving patient stratification in drug development, enhancing predictability of treatment efficacy [8] Policy Support - Significant government investments in brain science initiatives, such as the U.S. "Brain Initiative" with over $4 billion funding from 2014 to 2023, and China's brain plan with a budget exceeding 5 billion yuan, are fostering growth in the sector [8] Treatment Paradigms - The treatment landscape for Alzheimer's is evolving, with new therapies targeting Tau proteins gaining prominence over traditional Aβ-targeting approaches [9] - Innovations in drug delivery methods, such as brain-penetrating antibodies and RNAi technologies, are redefining treatment boundaries in neuroscience [11][12] Conclusion - After decades of exploration, the neuroscience field is experiencing unprecedented research intensity and commercialization, marking the onset of a new "gold rush" in the industry [13]

事件 群益证券发布研报称，预计复星医药（600196）(02196)2025-2027年分别实现净利润33.2亿元、46.8亿 元、47.7亿元，YOY分别+19.9%、+40.8%、+2.1%，EPS分别为1.2元、1.8元、1.8元，对应H股PE分别 为15X/11X/11X，H股估值偏低，看好其长期发展，维持"买进"的投资评级。 群益证券主要观点如下： 公司控股子公司复宏汉霖授予日本卫材Eisai(东京交易所上市，代码4523.T)于日本用于肿瘤适应症治疗 的开发、生产及商业化斯鲁利单抗注射液的权利。根据约定，Eisai应就许可产品向复宏汉霖支付至多 15501万美元不可退还的首付款、监管里程碑款项，其中首付款7500万美元，至多8001万美元监管里程 碑付款。此外，公司还将基于许可区域日本年度的净销额达成情况，至多获得23333万美元的销售里程 碑付款，并可基于产品销售额，获得双位元数比例的销售提成。 风险提示：新产品研发进度及销售不及预期，药品集采及国谈降价超预期，商誉减值风险。 新市场及新适应症持续开拓中 斯鲁利单抗联合化疗一线治疗ES-SCLC的美国桥接试验正在有序进行，在日本的桥接试验也在稳步 ...

Group 1 - The core viewpoint of the report is that Fosun Pharma (02196) is expected to achieve net profits of 3.32 billion yuan, 4.68 billion yuan, and 4.77 billion yuan from 2025 to 2027, with year-over-year growth rates of +19.9%, +40.8%, and +2.1% respectively, indicating a positive long-term outlook and a "buy" rating maintained by Yuanta Securities [1] - The company’s subsidiary, Fuhong Hanlin, has granted Eisai the rights for the development, production, and commercialization of the PD-1 monoclonal antibody, Surulitinib, in Japan, with a total upfront payment and milestone payments potentially reaching up to $155.01 million [1] - The upfront payment includes $75 million and up to $80.01 million in regulatory milestone payments, along with potential sales milestone payments of up to $23.33 million based on annual net sales in Japan [1] Group 2 - Surulitinib, a PD-1 monoclonal antibody developed by the company, was launched in China in March 2022 and is expected to generate revenue of 1.31 billion yuan in 2024, reflecting a year-over-year growth of +17.2% [2] - The product has received EU approval for first-line treatment of SCLC in February 2025, making it the first PD-1 monoclonal antibody approved in the EU for this indication, and has also been approved in several other countries, enhancing its international market presence [2] - The company is actively expanding into new markets and indications, with ongoing clinical trials for Surulitinib in various cancers and a new application for gastric cancer treatment expected to be accepted by the Chinese regulatory authority by December 2025 [3]

2026 年 02 月 06 日 | C0062@capital.com.tw | | | --- | --- | | 王睿哲 目标价(港元) | 26.5 | 公司基本资讯 | 产业别 | | 医药生物 | | --- | --- | --- | | H 股价(2026/2/5) | | 20.52 | | 恒生指数(2026/2/5) | | 26,885.24 | | 股价 12 个月高/低 | | 28.80/12.61 | | 总发行股数(百万) | | 2,670.43 | | H 股数(百万) | | 540.97 | | H 市值(亿港元) | | 111.01 | | | | 上海复星高科技 | | 主要股东 | | (集团)有限公司 | | | | (36.15%) | | 每股净值(元) | | 18.06 | | 股价/帐面净值 | | 1.14 | | | 一个月 | 三个月 一年 | | 股价涨跌(%) | -0.97% | -9.92% 62.68% | 近期评等 | 出刊日期 | 前日收盘 | 评等 | | --- | --- | --- | | 2025/12/10 | 21 ...

2026 年 02 月 06 日 | C0062@capital.com.tw | | | --- | --- | | 王睿哲 目标价(港元) | 26.5 | 公司基本资讯 | 产业别 | | 医药生物 | | --- | --- | --- | | H 股价(2026/2/5) | | 20.52 | | 恒生指数(2026/2/5) | | 26,885.24 | | 股价 12 个月高/低 | | 28.80/12.61 | | 总发行股数(百万) | | 2,670.43 | | H 股数(百万) | | 540.97 | | H 市值(亿港元) | | 111.01 | | | | 上海复星高科技 | | 主要股东 | | (集团)有限公司 | | | | (36.15%) | | 每股净值(元) | | 18.06 | | 股价/帐面净值 | | 1.14 | | | 一个月 | 三个月 一年 | | 股价涨跌(%) | -0.97% | -9.92% 62.68% | 近期评等 C o m p a n y U p d a t e C h i n a R e s e a r c h D e p ...

据悉，斯鲁利单抗是复宏汉霖自主研发的一款创新抗PD-1单克隆抗体。在中国，斯鲁利单抗已获批用 于多项适应症，包括鳞状非小细胞肺癌(sqNSCLC)、广泛期小细胞肺癌(ES-SCLC)、非鳞状非小细胞肺 癌(nsqNSCLC)以及食管鳞状细胞癌(ESCC)。在欧盟，斯鲁利单抗已获批用于ES-SCLC适应症，并成为 全球首个用于ES-SCLC一线治疗的抗PD-1单抗。 复宏汉霖(02696)早盘涨超5%，截至发稿，涨4.64%，报63.15港元，成交额3262.22万港元。 消息面上，复宏汉霖公告，公司将抗PD-1单抗H药汉斯状(斯鲁利单抗)日本权益授权给卫材。卫材将向 复宏汉霖支付7,500万美元的首付款，并在此基础上，支付最高不超过8,001万美元的监管里程碑付款， 以及最高不超过2.333亿美元的销售里程碑付款。此外，复宏汉霖还将基于产品销售额获得双位数比例 的销售提成。 ...

据悉，斯鲁利单抗是复宏汉霖自主研发的一款创新抗PD-1单克隆抗体。在中国，斯鲁利单抗已获批用 于多项适应症，包括鳞状非小细胞肺癌(sqNSCLC)、广泛期小细胞肺癌(ES-SCLC)、非鳞状非小细胞肺 癌(nsqNSCLC)以及食管鳞状细胞癌(ESCC)。在欧盟，斯鲁利单抗已获批用于ES-SCLC适应症，并成为 全球首个用于ES-SCLC一线治疗的抗PD-1单抗。 消息面上，复宏汉霖公告，公司将抗PD-1单抗H药汉斯状(斯鲁利单抗)日本权益授权给卫材。卫材将向 复宏汉霖支付7,500万美元的首付款，并在此基础上，支付最高不超过8,001万美元的监管里程碑付款， 以及最高不超过2.333亿美元的销售里程碑付款。此外，复宏汉霖还将基于产品销售额获得双位数比例 的销售提成。 智通财经APP获悉，复宏汉霖(02696)早盘涨超5%，截至发稿，涨4.64%，报63.15港元，成交额3262.22 万港元。 ...

2月5日，复宏汉霖与卫材共同宣布，双方已就抗PD-1单抗斯鲁利单抗，在日本达成一项独家商业化及 共同独家开发与生产许可协议。 根据协议，卫材将获得斯鲁利单抗在日本的独家商业化权益。除用于广泛期小细胞肺癌和非微卫星高度 不稳定型转移性结直肠癌的治疗外，复宏汉霖还计划在日本开展斯鲁利单抗用于胃癌围手术期治疗的临 床研究，并将承担该产品在日本的上市许可持有人（MAH）责任。 在日本， 广泛期小细胞肺癌与非微卫星高度不稳定型转移性结直肠癌患者群体规模分别约有1.3万与2.8 万人，这两类疾病均存在着高度未满足的临床需求。 Copyright © 2025 PHARMCUBE. All Rights Reserved. 免责申明：本微信文章中的信息仅供一般参考之 用，不可直接作为决策内容，医药魔方不对任何主体因使用本文内容而导致的任何损失承担责任。 2月5日，复宏汉霖与卫材共同宣布，双方已就抗PD-1单抗斯鲁利单抗，在日本达成一项独家商业化及 共同独家开发与生产许可协议。 卫材将向复宏汉霖支付7,500万美元的首付款（约合116亿日元*），并在此基础上，支付最高不超过 8,001万美元的监管里程碑付款（约合124亿日元 ...

Core Viewpoint - The article discusses the implementation and sales performance of the newly established commercial insurance innovative drug directory, highlighting the concentration of sales in major cities and the challenges faced in expanding access to these drugs across the country [3][7]. Summary by Sections Sales Performance of New Drug Directories - As of January 20, 2026, 99 new drugs from the basic medical insurance directory have been sold in 12,198 designated medical institutions, while 14 drugs from the commercial insurance innovative drug directory have been sold in 223 institutions [3][4]. - Over 70% of the commercial insurance innovative drugs have recorded sales, with Alzheimer's disease treatments showing the highest penetration in the hospital market [4][5]. Specific Drug Sales Insights - The drug Lecanemab, developed by Eisai, has been sold in 158 institutions, while Eli Lilly's Donanemab has been recorded in 46 institutions [4]. - The number of patients with mild cognitive impairment or mild dementia due to Alzheimer's disease in China is projected to reach 17 million by 2024, indicating a broad patient base for these treatments [5]. Challenges in Rare Disease Drug Sales - Rare disease drugs face challenges due to their limited patient populations and the concentration of prescriptions in specialized hospitals, resulting in sparse sales data [5][6]. - For instance, Takeda's drug for short bowel syndrome has only been sold in one designated pharmacy in Shenzhen this year [5]. Market Access and Policy Implications - Five innovative drugs have yet to achieve sales in designated medical institutions, including CAR-T products priced between 990,000 to 1.3 million yuan per injection [6]. - The National Healthcare Security Administration has implemented a "three exclusions" policy to facilitate the entry of high-cost drugs into hospitals, but the transition from "entry" to "sales" remains complex due to various factors [6][7]. Regional Disparities in Sales - Sales of commercial insurance innovative drugs are still concentrated in major provinces like Beijing, Shanghai, Jiangsu, and Guangdong, with retail pharmacies accounting for less than 10% of sales [7][8]. - Some regions, such as Guangdong and Chongqing, have begun to support the prescription flow of commercial insurance innovative drugs, but broader implementation is needed [8].