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John Jumper: AlphaFold and the Future of Science
Y Combinator· 2025-07-15 14:00
AI for Science & AlphaFold Overview - AI systems can accelerate scientific discovery and enable new breakthroughs, particularly in healthcare [1] - AlphaFold, a system developed for protein structure prediction, has been cited approximately 35,000 times, demonstrating its impact on scientific research [1] - The speaker's guiding principle is to build tools that enable scientists to make discoveries [1] Protein Structure Prediction & Biological Significance - Proteins, numbering around 20,000 different types in humans, perform nearly every function in a cell [1] - Determining protein structure is exceptionally difficult, often requiring years of effort and significant resources, costing around $100,000 [2] - There are approximately 200,000 known protein structures, with roughly 12,000 new structures being added annually [2] - Protein sequence discovery is happening approximately 3,000 times faster than protein structure determination [2] AlphaFold Development & Key Factors - AlphaFold's success was driven by data (200,000 protein structures), compute (128 TPU V3 cores for two weeks), and, most importantly, research and innovative ideas [2] - Research and novel ideas were approximately 100 times more valuable than the data used in training AlphaFold [3] - Mid-scale ideas, rather than just scaling transformers, are crucial for building transformative AI systems [2][3] Impact & Applications of AlphaFold - AlphaFold has enabled scientists to make discoveries in areas like vaccine and drug development, and understanding how the body works [1] - The release of the AlphaFold database, containing approximately 200 million protein structure predictions, significantly increased its adoption and impact [3] - Researchers are using AlphaFold in unexpected ways, such as predicting protein interactions and engineering proteins for targeted drug delivery [5][6] - AlphaFold is estimated to have accelerated the field of structural biology by approximately 5-10% [9]
Comscore Partners with HyphaMetrics to Launch Advanced Person-Level Audience Measurement and CTV Program-Level Reporting
Globenewswire· 2025-07-15 12:44
Core Insights - Comscore has announced a multi-year partnership with HyphaMetrics to enhance cross-platform measurement capabilities in the media industry [1][3] - The partnership will leverage HyphaMetrics' 'Unified Individual Media Metric' to provide a more precise understanding of audience behavior across various platforms [2][4] - This collaboration aims to deliver advanced reporting and insights into streaming behaviors, particularly for SVOD, AVOD, and FAST channels, in preparation for the 2026/2027 upfront season [3][4] Company Overview - Comscore is recognized as a global leader in measuring and analyzing consumer behaviors across digital, linear TV, and over-the-top platforms, providing reliable cross-platform measurement [5] - HyphaMetrics specializes in bridging the gap between TV and digital media through its proprietary technology that captures comprehensive audience behavior across all media consumption forms [6]
OppFi Soars 222% in a Year: Should Investors Buy, Hold, or Fold?
ZACKS· 2025-07-14 16:40
Core Insights - OppFi Inc. (OPFI) shares have surged 222.1% over the past year, significantly outperforming its industry growth of 10.3% and the Zacks S&P 500 Composite's 11% increase [1] - The stock has also shown strong performance over the last six months, increasing by 44.5%, compared to Mastercard's 6.3% and PayPal's 15.1% growth [4] Company Strategy - OppFi employs a bank-partner model that focuses on serving underbanked consumers with credit scores below 650, addressing a gap in traditional lending options [5] - The company has integrated AI and machine learning to enhance its service efficiency, achieving an auto-approval rate of 79% in Q1 2025, up from 73% in the same quarter the previous year [6][7] Customer Satisfaction - In Q1 2025, OppLoans received a 4.7 out of 5-star rating on Trustpilot from over 4,900 reviews, indicating strong customer satisfaction [8] - The company boasts a Net Promoter Score (NPS) of 78, reflecting a loyal customer base willing to promote the brand [8] Financial Metrics - OppFi shares are currently undervalued, trading at 9.27 times forward 12-month earnings per share, compared to the industry average of 21.68 times [9] - The trailing 12-month EV-to-EBITDA ratio for OPFI is 6.29 times, below the industry's average of 11.4 times [11] - The company's current ratio stands at 1.73 in Q1 2025, exceeding the industry average of 1.22, indicating strong liquidity [13] Revenue and Earnings Projections - The Zacks Consensus Estimate for OppFi's 2025 revenues is $578.4 million, reflecting a 10% year-over-year growth [15] - The consensus estimate for 2025 earnings per share is $1.23, implying a 29.5% year-over-year increase [15]
Why Shares of Nebius Group Are Rocketing Higher Today
The Motley Fool· 2025-07-14 16:16
Group 1 - The S&P 500 and Dow Jones Industrial Average are trending lower, while Nebius Group's stock is up 11.2% due to a favorable analyst outlook [1] - Goldman Sachs analyst Alexander Duval initiated coverage on Nebius with a buy rating and a price target of $68, indicating a potential upside of 53.5% from the previous closing price [3] - Nebius is recognized as a leader in the neocloud market, benefiting from its full stack software offerings and cost advantages, particularly for applications requiring high-performance infrastructure for GPUs [4] Group 2 - Nebius shares have risen nearly 100% in the first half of 2025, reflecting strong growth prospects in the AI sector [3][5] - Investing in Nebius is seen as a good opportunity for gaining exposure to AI, supported by the company's merits and growth potential [5]
ServiceNow's Workflow Adoption Rises: A Sign for More Upside?
ZACKS· 2025-07-14 15:56
Core Insights - ServiceNow (NOW) is experiencing growth due to increased adoption of its workflows by enterprises undergoing digital transformation [2] - The company secured 72 transactions exceeding $1 million in net new annual contract value (ACV) in Q1 2025, achieving a 20% year-over-year growth in its customer base with over $5 million in ACV [3][12] - ServiceNow is leveraging AI and machine learning to enhance its solutions, with its total addressable market projected to reach $275 billion by 2026 [4] Product Developments - In May 2025, ServiceNow launched its Core Business Suite, an AI-powered solution aimed at streamlining core business operations across various departments [5] - The frequent updates to the platform, occurring twice a year, are designed to simplify workflows and boost productivity for customers [4][12] Competitive Landscape - ServiceNow faces significant competition from Pegasystems and UiPath in the workflow automation space [7] - Pegasystems is gaining traction with its GenAI Blueprint solution, which is rapidly expanding, creating over 1,000 new Blueprints weekly [7][8] - UiPath continues to be a strong player in the Robotic Process Automation market, which is expected to grow substantially [9] Financial Performance - ServiceNow's shares have declined by 11.4% year to date, contrasting with a 7.5% return from the broader Zacks Computer & Technology sector [10] - The forward 12-month Price/Sales ratio for ServiceNow is 13.60X, significantly higher than the sector average of 6.59X [13] - The Zacks Consensus Estimate for Q2 2025 earnings is $3.54 per share, reflecting a 13.10% year-over-year increase, while the estimate for 2025 earnings is $16.54 per share, indicating an 18.43% growth [15]
Tevogen.AI Builds Alpha Version of PredicTcell™ Model with Microsoft and Databricks; Observes Drastic Time Reduction in Target Analysis Translating to Potential Savings of Billions in Drug Development Costs
Globenewswire· 2025-07-14 13:30
Core Viewpoint - Tevogen Bio Holdings Inc. has successfully developed the alpha version of its AI-driven PredicTcell™ model in collaboration with Microsoft and Databricks, aiming to revolutionize therapeutic development through enhanced target discovery and accelerated clinical research [1][3]. Group 1: Technology and Innovation - The PredicTcell model utilizes a terabyte-scale dataset with nearly a billion genetic and proteomic elements, significantly improving target discovery and reducing protein sequence analysis time from months to hours through advanced machine learning techniques [2][7]. - Tevogen.AI's initiatives are expected to streamline early-stage drug discovery, potentially generating billions in cost savings across the healthcare system and creating substantial top-line revenues for early adopters [7]. Group 2: Future Developments - The company plans to enhance the PredicTcell platform by expanding its datasets to include virology, oncology, and neurology, which may lead to improved accuracy and reduced time for wet lab testing [3][4]. - Additional advancements in clinical trial optimization and patient market analysis through the complementary AdapTcell™ model are anticipated to be announced in future communications [4].
How LLMs work for Web Devs: GPT in 600 lines of Vanilla JS - Ishan Anand
AI Engineer· 2025-07-13 17:30
Core Technology & Architecture - The workshop focuses on a GPT-2 inference implementation in Vanilla JS, providing a foundation for understanding modern AI systems like ChatGPT, Claude, DeepSeek, and Llama [1] - It covers key concepts such as converting raw text into tokens, representing semantic meaning through vector embeddings, training neural networks through gradient descent, and generating text with sampling algorithms [1] Educational Focus & Target Audience - The workshop is designed for web developers entering the field of ML and AI, aiming to provide a "missing AI degree" in two hours [1] - Participants will gain an intuitive understanding of how Transformers work, applicable to LLM-powered projects [1] Speaker Expertise - Ishan Anand, an AI consultant and technology executive, specializes in Generative AI and LLMs, and created "Spreadsheets-are-all-you-need" [1] - He has a background as former CTO and co-founder of Layer0 (acquired by Edgio) and VP of Product Management for Edgio, with expertise in web performance, edge computing, and AI/ML [1]
X @Avi Chawla
Avi Chawla· 2025-07-13 06:33
Product Overview - MindsDB is presented as a federated query engine with a built-in MCP server [1] - The platform supports querying data from over 200 sources, including Slack, Gmail, and social platforms [1] - MindsDB offers query capabilities in both SQL and natural language [1] - The platform is 100% open-source and has over 33 thousand stars [1]
Viewbix: Metagramm Unveils AI-Powered Grammar Solution for Enterprises Seeking Secure, Private, and Customized Language Models
Globenewswire· 2025-07-11 11:32
Core Insights - Viewbix Inc. announces the launch of an advanced on-premise grammar engine by its subsidiary Metagramm Software Ltd., aimed at enhancing linguistic accuracy for large organizations [1][3] - The new solution is designed to ensure data privacy and compliance with security regulations, differentiating it from generic cloud-based grammar tools [2][8] Company Overview - Metagramm specializes in AI-driven writing assistance tools, with its flagship product, Bubbl, focusing on personalized text generation [5] - Viewbix operates in digital advertising through subsidiaries, providing technological solutions for internet campaign automation and content creation across various platforms [6] Product Features - The grammar engine will be deployed on-premises, allowing total data control and privacy without external data sharing [8] - It will utilize custom language models trained on the user's internal documents and communication guidelines, ensuring industry-specific accuracy [8] - The solution supports multilingual capabilities and is tailored for sectors like finance, law, healthcare, and government, where precise communication is critical [8]
X @Avi Chawla
Avi Chawla· 2025-07-11 06:31
General Information - The content is a wrap-up and call to action to reshare the information [1] - The author shares tutorials and insights on Data Science (DS), Machine Learning (ML), Large Language Models (LLMs), and Retrieval Augmented Generation (RAGs) daily [1] Technical Focus - The author provides a clear explanation (with visuals) on how to sync GPUs in multi-GPU training [1]