延长健康寿命

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抗衰老公司NewLimit获1.3亿美元融资,硅谷亿万富翁创立,通过表观遗传重编程延长人类健康寿命
生物世界· 2025-05-07 07:30
Core Viewpoint - NewLimit aims to develop epigenetic reprogramming therapies to extend healthy lifespan and address aging-related diseases, having recently completed a $130 million Series B funding round, raising its valuation to $810 million [2][3]. Company Overview - NewLimit was founded in 2022 by experts including Blake Byers, Brian Armstrong, and Jacob Kimmel, focusing on epigenetic reprogramming to restore youthful functions in aging cells [2][3]. - The company has previously raised $150 million and is now valued at $810 million following the latest funding round [2]. Technology and Research Focus - NewLimit's primary goal is to develop drugs that reprogram aging cells to extend healthy lifespan, utilizing advanced technologies such as single-cell genomics, epigenetic editing, and machine learning [3]. - The company is currently working on a liver regeneration mRNA therapy aimed at treating aging-related diseases, with plans to advance it to clinical trials [3][7]. - The lead drug delivery method involves lipid nanoparticles (LNP) to deliver mRNA to liver cells, encoding transcription factors that rejuvenate cellular functions [7]. Long-term Vision and Market Strategy - NewLimit's long-term vision is to significantly extend human healthspan, with initial projects targeting the restoration of functions in aging liver, immune, and vascular systems [3]. - The company plans to follow a similar expansion strategy as GLP-1 drugs, starting with alcohol-related liver disease and potentially extending to broader metabolic syndrome treatments [4][7]. Industry Trends - The focus on extending "healthspan" is gaining traction, as evidenced by the recent launch of Etiome, a preventive medicine biotech company, which also aims to enhance human healthspan [8].