技术授权收入独木难支，毛利率"不适用"藏隐忧 2025年6月25日，益方生物（688382）发布对上交所2024年年报问询函的回复公告，揭开了这家创新药 企的业绩困境与经营挑战。年报数据显示，公司全年营业收入1.69亿元，归母净利润亏损2.40亿元，亏 损同比扩大14.5%。尽管技术授权收入撑起营收，但核心产品贝福替尼1.8亿元里程碑款逾期、毛利 率"不适用"等异常指标引发监管关注。 2024年，益方生物96%的收入依赖技术授权及销售提成。其中，格索雷塞研发里程碑收入1.51亿元（占 比89%），贝福替尼销售提成1637.86万元（9.7%）。公司称收入确认符合会计准则，以产品获批上市 或销售完成时点为准。例如，格索雷塞因2024年11月获批上市，一次性确认正大天晴支付的1.6亿元里 程碑款。 然而，营业成本仅392.39万元，主要为贝福替尼2%的销售额分成支付给第三方技术授权费。由于收入 结构以一次性里程碑款为主，导致毛利率指标"不适用"，凸显业绩波动风险。 1.8亿应收逾期暴露合作方资金压力，坏账计提引质疑 公告披露，贝达药业因"资金安排"逾期支付贝福替尼里程碑款1.8亿元，占应收账款总额的77%。尽管公 ...

2025 年 6 月 17 日 医药: 超配 证券研究报告 / 公司更新报告 石药 (1093 HK, 买入, 目标价: HK$10.59) | 买入 | | --- | | 目标价: HK$10.59 | 当前股价: HK$8.84 | | --- | --- | | 股价上行/下行空间 | +20% | | 52 周最高/最低价 (HK$) | 9.48/4.27 | | 市值 (US$mn) | 13,462 | | 当前发行数量(百万股) | 11,954 | | 三个月平均日交易額 | 164 | | (US$mn) | | | 流通盘占比 (%) | 41 | | 主要股东 (%) | | | 鼎大集团有限公司 | 10 | | 联诚控股有限公司 | 8 | | 共成国际 | 6 | | 按 2025 年 6 月 13 日收市数据 | | | 资料来源: FactSet | | 主要调整 | | 现值 | 原值 | 变动 | | --- | --- | --- | --- | | 评级 | 买入 | 买入 | N/A | | 目标价 (HK$) | 10.59 | 8.88 | 19% | | 2 ...

Financial Data and Key Metrics Changes - Consolidated net revenue decreased by 7% year over year to $555 million [21] - Consolidated AOI declined by 30% to $104 million, with a 19% margin [21] - Adjusted EPS was reported at $0.52 [21] - Free cash flow for the quarter was $94 million, on track to achieve approximately $220 million for the full year [20][31] Business Line Data and Key Metrics Changes - Domestic operations revenue decreased by 7% to $486 million, with subscription revenue down by 3% due to a 12% decline in affiliate revenue, partially offset by 8% growth in streaming revenue [21][22] - Advertising revenue in domestic operations decreased by 15% year over year, primarily due to lower linear ratings [25] - International revenue for the first quarter was $70 million, down 7%, with subscription revenue decreasing by 12% due to the non-renewal with Movistar in Spain [27] Market Data and Key Metrics Changes - Streaming subscribers at the end of the quarter were 10.2 million, flat compared to the prior year, with a slight decline from 10.4 million at the end of 2024 [24] - Advertising revenue from streaming is still in the low single digits but provides incremental revenue opportunities [48][49] Company Strategy and Development Direction - The company is focused on programming, partnerships, and profitability, emphasizing the generation of free cash flow [5][32] - Strategic initiatives include launching ad-supported versions of AMC Plus and Shudder, and expanding partnerships with distributors like Charter and Comcast [7][10] - The company aims to enhance its content distribution ecosystem and improve viewer experience through partnerships [36][38] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's strategic direction despite macroeconomic uncertainties affecting the advertising market [32] - The company anticipates streaming revenue growth to accelerate as the year progresses, driven by pricing actions and new series debuts [25][31] - Management remains vigilant regarding potential impacts from the advertising market but has not seen meaningful indicators suggesting a material pullback [32][44] Other Important Information - The company has a healthy cash position with net debt of $1.5 billion and a consolidated net leverage ratio of 2.9 times [29] - The company has no bond maturities until 2029 and maintains over $1 billion in total liquidity [29] Q&A Session Summary Question: Can you tell us about the streaming subscribers coming in through bundled video packages? - Management is pleased with the integration with Charter and the anticipated take rates for embedded streaming services [35] Question: Are you seeing any risk of cannibalization on the a la carte side? - Management believes that expanding distribution will create a healthier video ecosystem and additional revenue opportunities [38] Question: How much of your advertising is coming from streaming? - Streaming advertising delivers incremental revenue, and the company is confident in its genre-based services [49] Question: When will you lap the subscription revenue issues from the Spanish drop? - Management anticipates growth in the Spanish market with other partners and is optimistic about future relationships with Movistar [50][51] Question: What do you expect content spend and content amortization to be this year? - Content amortization is expected to be slightly lower year over year, with cash content spend also down slightly [69]